DAPAGZA L 10MG/5MG TABLET 10'S

How DAPAGZA L 10MG/5MG TABLET 10'S Works

• DAPAGZA L 10MG/5MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Dapagliflozin and Linagliptin, each working through distinct mechanisms to improve glycemic control.
• Dapagliflozin belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin works by selectively inhibiting SGLT2. By blocking SGLT2, Dapagliflozin reduces the reabsorption of glucose in the kidneys, allowing excess glucose to be excreted through urine. This action lowers blood glucose levels without directly affecting insulin secretion. Furthermore, the excretion of glucose also leads to a loss of calories, which can contribute to weight loss.
• Linagliptin, on the other hand, is a Dipeptidyl Peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (Glucagon-like peptide-1) and GIP (Glucose-dependent insulinotropic polypeptide), are released from the gut in response to food intake. They stimulate insulin release from the pancreas and decrease glucagon secretion from the liver, both of which help lower blood glucose levels. By inhibiting DPP-4, Linagliptin prolongs the activity of incretin hormones, thereby increasing insulin secretion and decreasing glucagon secretion in a glucose-dependent manner. This means that Linagliptin's effects are more pronounced when blood glucose levels are high, reducing the risk of hypoglycemia (low blood sugar).
• In summary, DAPAGZA L 10MG/5MG TABLET 10'S works through a dual mechanism: Dapagliflozin reduces glucose reabsorption in the kidneys, leading to glucose excretion, while Linagliptin enhances the effects of incretin hormones, promoting insulin release and suppressing glucagon secretion. The combination of these two drugs provides complementary actions to effectively lower blood glucose levels in patients with type 2 diabetes.
• It is crucial to use DAPAGZA L 10MG/5MG TABLET 10'S as directed by your healthcare provider. They will determine the appropriate dosage based on your individual needs and monitor your response to the medication. Always inform your doctor about any other medications you are taking and any existing medical conditions you have before starting this medication.

The following side effects have been reported with DAPAGZA L 10MG/5MG TABLET. Common side effects include: Hypoglycemia (low blood glucose), Genital infection, Urinary tract infection, Increased urination, Changes in cholesterol levels, Nausea, Vomiting, Diarrhea, Constipation, Thirst, Increased uric acid in blood, Dizziness, Headache, Back pain, Joint pain. Less common or rare side effects may include: Diabetic ketoacidosis (a serious complication of diabetes), Kidney problems, Allergic reactions (rash, itching, swelling), and Liver problems. Consult your doctor if you experience any persistent or worsening side effects.

• If you miss a dose of DAPAGZA L 10MG/5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DAPAGZA L 10/5MG TAB 1X10 away from the reach of children and pets.
• Store DAPAGZA L 10/5MG TAB 1X10 at room temperature.

• **Take DAPAGZA L 10MG/5MG TABLET 10'S exactly as prescribed by your doctor.** Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once daily, with or without food, preferably at the same time each day to maintain consistent blood levels and maximize its effectiveness in managing your blood sugar.
• **Stay hydrated while taking DAPAGZA L 10MG/5MG TABLET 10'S.** Drink plenty of water throughout the day, especially during hot weather or when exercising. This helps prevent dehydration, which can sometimes occur with this medication due to its diuretic effect. Adequate hydration supports kidney function and overall health while managing your diabetes.
• **Monitor your blood sugar levels regularly as directed by your doctor.** DAPAGZA L 10MG/5MG TABLET 10'S helps control blood sugar, but regular monitoring is essential to ensure the medication is working effectively and to adjust your treatment plan if needed. Keep a log of your blood sugar readings and share it with your healthcare provider during your appointments.
• **Be aware of the symptoms of low blood sugar (hypoglycemia).** Although DAPAGZA L 10MG/5MG TABLET 10'S has a low risk of causing hypoglycemia when used alone, it can occur when combined with other diabetes medications, insulin, or changes in diet or exercise. Common symptoms include shakiness, sweating, dizziness, confusion, and hunger. If you experience these symptoms, check your blood sugar and follow your doctor's instructions for treating hypoglycemia.
• **Inform your doctor about all other medications you are taking, including over-the-counter drugs, supplements, and herbal remedies.** Drug interactions can affect how DAPAGZA L 10MG/5MG TABLET 10'S works or increase your risk of side effects. Your doctor needs a complete list of your medications to ensure safe and effective treatment.
• **Maintain a healthy lifestyle while taking DAPAGZA L 10MG/5MG TABLET 10'S.** This includes following a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. Lifestyle modifications can significantly improve your blood sugar control and overall health, complementing the effects of the medication. Work with a registered dietitian or certified diabetes educator to develop a personalized plan.

• Dapagza L 10mg/5mg Tablet 10's can be taken with or without food. Food does not significantly affect the absorption or efficacy of this medication. Follow your doctor's instructions regarding dosage and timing.