JUSLINA D 5/10 TABLET 10'S
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JUSLINA D 5/10 TABLET 10'S
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JUSLINA D 5/10 TABLET 10'S

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JUSLINA D 5/10 TABLET 10'S

By MANKIND PHARMA LIMITED

MRP

141.59

₹120.35

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10

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About JUSLINA D 5/10 TABLET 10'S

  • JUSLINA D 5/10 Tablet is a combination medication designed to effectively manage blood sugar levels in individuals diagnosed with type 2 diabetes. This oral anti-diabetic medicine combines two powerful active ingredients to provide comprehensive glycemic control.
  • The first key ingredient, Vildagliptin, belongs to a class of drugs known as DPP-4 inhibitors. Vildagliptin works by increasing the amount of insulin released by the pancreas after meals and decreasing the amount of glucagon produced by the liver. Glucagon is a hormone that raises blood sugar levels, so by reducing its production, Vildagliptin helps to lower blood sugar levels.
  • The second active ingredient, Dapagliflozin, is an SGLT2 inhibitor. It functions by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated from the body through urine, which helps to lower blood sugar levels.
  • Together, Vildagliptin and Dapagliflozin offer a dual-action approach to managing type 2 diabetes. By targeting different mechanisms in the body, they provide synergistic benefits in controlling blood sugar levels. This combination helps to improve glycemic control, reduce the risk of diabetes-related complications, and enhance overall well-being for individuals with type 2 diabetes.
  • JUSLINA D 5/10 Tablet is typically taken once daily, preferably in the morning, with or without food. However, it is essential to follow your doctor's instructions regarding dosage and timing. Regular monitoring of blood sugar levels, along with a healthy diet and regular exercise, is crucial for optimal diabetes management while taking this medication. It is important to consult with your healthcare provider for personalized advice and to address any concerns or potential side effects.

Uses of JUSLINA D 5/10 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Increasing insulin sensitivity
  • Managing diabetes in patients with kidney disease (at doctor's discretion)

How JUSLINA D 5/10 TABLET 10'S Works

  • JUSLINA D 5/10 TABLET 10'S is a combination medication containing two active ingredients: Dapagliflozin and Vildagliptin. These medications work through complementary mechanisms to lower blood sugar levels in individuals with type 2 diabetes. Dapagliflozin belongs to a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors, while Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
  • Dapagliflozin works primarily in the kidneys. In healthy individuals, the kidneys filter glucose from the blood, and then reabsorb it back into the bloodstream. Dapagliflozin blocks the action of SGLT2, a protein in the kidneys responsible for reabsorbing glucose. By inhibiting SGLT2, Dapagliflozin reduces the reabsorption of glucose, leading to increased glucose excretion in the urine. This process effectively lowers blood glucose levels. Because it works independently of insulin, Dapagliflozin carries a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications. Furthermore, the excretion of glucose through urine can also contribute to modest weight loss in some patients.
  • Vildagliptin, on the other hand, works by enhancing the activity of incretin hormones. Incretins are hormones released by the gut in response to food intake. They stimulate the release of insulin from the pancreas and reduce the secretion of glucagon, another hormone that raises blood sugar. DPP-4 is an enzyme that breaks down incretin hormones, reducing their effectiveness. Vildagliptin inhibits DPP-4, thereby increasing the levels of active incretin hormones in the body. This leads to increased insulin secretion (when blood sugar is high) and decreased glucagon secretion, both of which contribute to lower blood sugar levels. Vildagliptin's mechanism of action is glucose-dependent, meaning it primarily affects insulin and glucagon secretion when blood sugar is elevated, further minimizing the risk of hypoglycemia.
  • In combination, Dapagliflozin and Vildagliptin provide a dual-pronged approach to managing blood sugar. Dapagliflozin reduces glucose reabsorption in the kidneys, while Vildagliptin enhances incretin activity, improving insulin secretion and reducing glucagon secretion. This synergistic effect can lead to better glycemic control compared to using either medication alone. This combination helps to improve glycemic control, reduce the risk of cardiovascular events, and promote overall well-being in patients with type 2 diabetes, when used in conjunction with diet and exercise.
  • It's important to note that JUSLINA D 5/10 TABLET 10'S is typically prescribed as part of a comprehensive diabetes management plan, which includes lifestyle modifications such as diet and exercise. Regular monitoring of blood sugar levels is essential to ensure the medication is working effectively and to adjust the dosage if needed. Patients should also be aware of potential side effects and discuss any concerns with their healthcare provider.

Side Effects of JUSLINA D 5/10 TABLET 10'SArrow

Like all medicines, JUSLINA D 5/10 TABLET 10'S can cause side effects, although not everybody gets them.\n\n**Common Side Effects:**\n\n* Hypoglycemia (low blood sugar) - Symptoms may include sweating, shakiness, anxiety, blurred vision, rapid heartbeat, dizziness, or headache.\n* Gastrointestinal issues like nausea, vomiting, diarrhea, or constipation.\n* Headache\n* Dizziness\n* Upper respiratory tract infection\n* Urinary tract infection\n* Peripheral edema (swelling in the extremities)\n* Weight gain\n\n**Uncommon Side Effects:**\n\n* Joint pain (Arthralgia)\n* Muscle pain (Myalgia)\n* Back pain\n* Increased liver enzymes\n* Allergic reactions (rash, itching, hives)\n* Anemia\n\n**Rare Side Effects:**\n\n* Pancreatitis (inflammation of the pancreas) - Symptoms include severe abdominal pain, nausea, and vomiting.\n* Severe allergic reactions (anaphylaxis) - Symptoms include difficulty breathing, swelling of the face, lips, tongue, or throat, and a rapid heartbeat.\n* Kidney problems\n* Liver problems\n\n**Important Note:** This is not an exhaustive list. If you experience any unusual or concerning symptoms while taking JUSLINA D 5/10 TABLET 10'S, stop taking the medicine and consult your doctor immediately. It's crucial to promptly report any potential side effects to your healthcare provider.

Safety Advice for JUSLINA D 5/10 TABLET 10'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it or any of its ingredients.

Dosage of JUSLINA D 5/10 TABLET 10'SArrow

  • The recommended dosage of JUSLINA D 5/10 TABLET 10'S is highly individualized and depends on various factors, including the patient's specific condition, the severity of their diabetes, their kidney function, other medications they may be taking, and their overall health status. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule. Never self-adjust the dose or discontinue the medication without consulting your healthcare provider.
  • Typically, JUSLINA D 5/10 is taken once daily, usually in the morning with or without food. Consistent timing helps maintain steady blood glucose levels throughout the day. Your doctor will likely start you on a low dose and gradually increase it as needed to achieve optimal glycemic control while minimizing the risk of side effects, such as hypoglycemia (low blood sugar).
  • If you miss a dose of JUSLINA D 5/10 TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Regular monitoring of blood glucose levels is essential while taking JUSLINA D 5/10 TABLET 10'S. Your doctor will advise you on how frequently to check your blood sugar and what to do if your blood sugar levels are too high or too low.
  • Take 'JUSLINA D 5/10 TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of JUSLINA D 5/10 TABLET 10'S?Arrow

  • If you miss a dose of JUSLINA D 5/10 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store JUSLINA D 5/10 TABLET 10'S?Arrow

  • Keep JUSLINA D 5/10MG TAB 1X10 away from the reach of children and pets.
  • Store JUSLINA D 5/10MG TAB 1X10 at room temperature.

Benefits of JUSLINA D 5/10 TABLET 10'SArrow

  • JUSLINA D 5/10 Tablet 10's offers a dual-action approach to managing type 2 diabetes. By combining two active ingredients, it provides a more comprehensive control over blood sugar levels than using a single medication. This synergistic effect helps in achieving and maintaining target glucose levels, reducing the risk of long-term complications associated with diabetes.
  • One of the primary benefits of JUSLINA D 5/10 is its ability to improve insulin sensitivity. This means that the body becomes more responsive to the insulin it produces, allowing glucose to be utilized more effectively by cells for energy. This is particularly beneficial for individuals with insulin resistance, a common characteristic of type 2 diabetes.
  • JUSLINA D 5/10 also helps to reduce the amount of glucose produced by the liver. In individuals with diabetes, the liver often produces excessive amounts of glucose, contributing to high blood sugar levels. By inhibiting this process, JUSLINA D 5/10 helps to lower fasting blood sugar levels and improve overall glycemic control.
  • Furthermore, JUSLINA D 5/10 aids in slowing down the absorption of glucose from the intestines after meals. This helps to prevent rapid spikes in blood sugar levels following food intake, which is crucial for managing postprandial hyperglycemia.
  • Another significant advantage of JUSLINA D 5/10 is its potential to protect pancreatic beta cells. By improving glycemic control and reducing the workload on the pancreas, it can help preserve the function of these cells, which are responsible for producing insulin. This can slow down the progression of diabetes and reduce the need for higher doses of medication over time.
  • JUSLINA D 5/10 can also contribute to weight management. Some individuals with type 2 diabetes experience weight gain as a result of their condition or medications. JUSLINA D 5/10 may have a more neutral effect on weight, or even promote modest weight loss, which can further improve glycemic control and reduce cardiovascular risk factors.
  • The use of JUSLINA D 5/10 can lead to a reduction in HbA1c levels, a measure of average blood sugar control over the past 2-3 months. Lowering HbA1c levels is associated with a decreased risk of developing diabetes-related complications, such as heart disease, kidney disease, nerve damage, and eye damage.
  • JUSLINA D 5/10 offers the convenience of a single tablet containing two medications, which can improve adherence to treatment. This simplifies the medication regimen and reduces the burden on patients, making it easier to manage their diabetes effectively. Improved adherence translates to better blood sugar control and improved overall health outcomes.
  • By effectively managing blood sugar levels, JUSLINA D 5/10 helps in reducing the risk of cardiovascular events, such as heart attacks and strokes. People with diabetes are at an increased risk of these complications, and controlling blood sugar is a crucial step in mitigating this risk.
  • Finally, JUSLINA D 5/10 can improve the overall quality of life for individuals with type 2 diabetes. By helping to control blood sugar levels, it can reduce symptoms such as fatigue, frequent urination, and excessive thirst, allowing individuals to lead more active and fulfilling lives.

How to use JUSLINA D 5/10 TABLET 10'SArrow

  • JUSLINA D 5/10 TABLET 10'S should be taken orally, usually once daily, preferably in the morning. This helps maintain consistent blood sugar levels throughout the day. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment. It's crucial to follow their instructions precisely.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. Taking it with water ensures proper absorption.
  • You can take JUSLINA D 5/10 TABLET 10'S with or without food. However, if you experience any stomach upset, taking it with a meal may help. Consistency is key, so try to take it around the same time each day, regardless of whether you eat or not.
  • Continue taking JUSLINA D 5/10 TABLET 10'S even if you feel well. Many people with type 2 diabetes don't experience noticeable symptoms, so it's important to adhere to your prescribed treatment plan. Do not stop taking the medication without consulting your doctor, as this could lead to a rise in blood sugar levels.
  • It is essential to combine JUSLINA D 5/10 TABLET 10'S with a healthy diet and regular exercise. This medication works best when combined with lifestyle modifications. Follow a balanced diet low in sugar and saturated fats, and engage in at least 30 minutes of moderate-intensity exercise most days of the week.
  • If you miss a dose of JUSLINA D 5/10 TABLET 10'S, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Store JUSLINA D 5/10 TABLET 10'S at room temperature, away from heat, light, and moisture. Keep the medication out of reach of children. If you have any questions or concerns about using JUSLINA D 5/10 TABLET 10'S, consult your doctor or pharmacist.

Quick Tips for JUSLINA D 5/10 TABLET 10'SArrow

  • Take JUSLINA D 5/10 TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this can affect your blood sugar levels.
  • Monitor your blood sugar levels regularly while taking JUSLINA D 5/10 TABLET 10'S. Keep a record of your blood glucose readings and share them with your doctor. This will help in assessing how well the medication is working for you and whether any adjustments are needed.
  • Follow a healthy diet and exercise regularly while using JUSLINA D 5/10 TABLET 10'S. This medication works best when combined with lifestyle changes. Focus on incorporating fiber-rich foods, lean protein, and healthy fats into your diet. Regular physical activity can also improve your body's response to the medication.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). Hypoglycemia symptoms can include shakiness, sweating, dizziness, and confusion. Hyperglycemia symptoms can include increased thirst, frequent urination, and blurred vision. Knowing these symptoms will help you take prompt action if your blood sugar levels become too low or too high.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting JUSLINA D 5/10 TABLET 10'S. Some medications can interact with this drug, potentially affecting its efficacy or increasing the risk of side effects. This includes over-the-counter medications and herbal remedies.

Food Interactions with JUSLINA D 5/10 TABLET 10'SArrow

  • While taking JUSLINA D 5/10 TABLET 10'S, it's generally recommended to maintain a consistent dietary pattern. This medication can be taken with or without food. However, if you experience stomach upset, taking it with food might help. Avoid excessive alcohol consumption, as it can potentially increase the risk of side effects or affect blood sugar control. Always follow your doctor's specific instructions regarding diet and medication timing.

FAQs

What is JUSLINA D 5/10 TABLET used for?Arrow

JUSLINA D 5/10 TABLET is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does JUSLINA D 5/10 TABLET work?Arrow

JUSLINA D 5/10 TABLET contains dapagliflozin and sitagliptin. Dapagliflozin works by blocking the reabsorption of sugar by the kidneys, causing more sugar to be excreted in the urine. Sitagliptin works by inhibiting the DPP-4 enzyme, increasing insulin production and decreasing sugar production.

What are the common side effects of JUSLINA D 5/10 TABLET?Arrow

Common side effects of JUSLINA D 5/10 TABLET include genital infections, urinary tract infections, nausea, and headache.

Does JUSLINA D 5/10 TABLET cause weight loss?Arrow

JUSLINA D 5/10 TABLET may cause weight loss in some patients, but it is not a common side effect.

How should I store JUSLINA D 5/10 TABLET?Arrow

Store JUSLINA D 5/10 TABLET at room temperature, away from moisture and light. Keep it out of reach of children and pets.

Is JUSLINA D 5/10 TABLET safe during pregnancy?Arrow

The safety of JUSLINA D 5/10 TABLET during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is JUSLINA D 5/10 TABLET safe during breastfeeding?Arrow

It is not known whether JUSLINA D 5/10 TABLET is excreted in breast milk. Consult your doctor before using it during breastfeeding.

Is JUSLINA D 5/10 TABLET safe for patients with kidney disease?Arrow

JUSLINA D 5/10 TABLET should be used with caution in patients with kidney disease. Your doctor may need to adjust your dosage.

Is JUSLINA D 5/10 TABLET safe for patients with liver disease?Arrow

JUSLINA D 5/10 TABLET should be used with caution in patients with liver disease. Your doctor may need to adjust your dosage.

What are the symptoms of an overdose of JUSLINA D 5/10 TABLET?Arrow

Symptoms of an overdose of JUSLINA D 5/10 TABLET may include nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it can cause hypoglycemia (low blood sugar).

Can JUSLINA D 5/10 TABLET interact with other medications?Arrow

JUSLINA D 5/10 TABLET can interact with certain other medications, such as insulin and sulfonylureas. Tell your doctor about all the medications you are taking.

How long should I take JUSLINA D 5/10 TABLET?Arrow

Take JUSLINA D 5/10 TABLET exactly as prescribed by your doctor. It is usually taken for a long period.

What happens if I miss a dose of JUSLINA D 5/10 TABLET?Arrow

If you miss a dose of JUSLINA D 5/10 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can I drink alcohol while taking JUSLINA D 5/10 TABLET?Arrow

Drinking alcohol while taking JUSLINA D 5/10 TABLET can increase the risk of hypoglycemia (low blood sugar). It is best to limit alcohol consumption.

Are there any serious side effects of JUSLINA D 5/10 TABLET?Arrow

Serious side effects of JUSLINA D 5/10 TABLET can include ketoacidosis (build-up of ketones in the blood), acute pancreatitis (inflammation of the pancreas), and severe allergic reactions in rare cases. Seek immediate medical attention if you experience any serious side effects.

References

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DrugBank: Dapagliflozin. Provides detailed chemical, pharmacological, and clinical information on Dapagliflozin, an ingredient in JUSLINA D.

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FDA Prescribing Information: Farxiga (dapagliflozin) tablets. This is the official FDA label for dapagliflozin, offering comprehensive details.

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European Medicines Agency (EMA): Forxiga. EPAR provides scientific discussion and regulatory information about dapagliflozin.

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FDA Prescribing Information: Metformin Hydrochloride. Contains prescribing information for Metformin Hydrochloride.

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DrugBank: Metformin. Provides detailed information regarding the mechanism of action, pharmacology, and uses of metformin.

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Marketer / Manufacturer Details

MANKIND PHARMA LIMITED

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India

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