DAPAVEL L 10/5MG TABLET 10'S
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DAPAVEL L 10/5MG TABLET 10'SDAPAVEL L 10/5MG TABLET 10'SDAPAVEL L 10/5MG TABLET 10'SDAPAVEL L 10/5MG TABLET 10'S
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DAPAVEL L 10/5MG TABLET 10'S

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DAPAVEL L 10/5MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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186.75

₹158.74

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About DAPAVEL L 10/5MG TABLET 10'S

  • DAPAVEL L 10/5MG TABLET 10'S is a combination medication designed to manage blood sugar levels in adults with type 2 diabetes. It combines two powerful active ingredients: Dapagliflozin and Linagliptin, working synergistically to provide comprehensive glycemic control.
  • Dapagliflozin belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated through urine, effectively lowering blood sugar levels. This mechanism is particularly beneficial as it reduces the risk of hypoglycemia (low blood sugar) compared to some other diabetes medications.
  • Linagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It enhances the levels of incretin hormones in the body. Incretins are naturally produced hormones that stimulate insulin release from the pancreas and decrease the secretion of glucagon (a hormone that raises blood sugar) after meals. By increasing incretin levels, Linagliptin helps to regulate blood sugar in a glucose-dependent manner.
  • DAPAVEL L 10/5MG is typically prescribed as an adjunct to diet and exercise to improve glycemic control in patients whose diabetes is not adequately controlled with either Dapagliflozin or Linagliptin alone. It is taken orally once daily, with or without food. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment.
  • Before taking DAPAVEL L 10/5MG, inform your doctor about any existing medical conditions, especially kidney problems, liver problems, heart failure, or a history of pancreatitis. Also, disclose all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions. Common side effects may include urinary tract infections, genital infections, and increased urination. It's important to stay well-hydrated while taking this medication.
  • This medication is a prescription drug and should be taken under the guidance of a healthcare professional. Regular monitoring of blood sugar levels and kidney function is recommended during treatment. If you experience any unusual or severe side effects, consult your doctor promptly.

Uses of DAPAVEL L 10/5MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing the risk of heart failure (in some patients)
  • Slowing the progression of kidney disease (in some patients)
  • Reducing cardiovascular risk (in high-risk patients)

How DAPAVEL L 10/5MG TABLET 10'S Works

  • DAPAVEL L 10/5MG TABLET 10'S is a combination medication containing dapagliflozin and linagliptin, designed to manage blood sugar levels in adults with type 2 diabetes. It works through complementary mechanisms to improve glycemic control.
  • Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. By inhibiting SGLT2, dapagliflozin reduces the reabsorption of glucose, causing excess glucose to be excreted in the urine. This lowers blood sugar levels and can also lead to modest weight loss.
  • Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that inactivates incretin hormones. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released from the gut in response to food intake. They stimulate insulin release from the pancreas and decrease glucagon secretion from the liver, both of which help lower blood sugar levels. By inhibiting DPP-4, linagliptin increases the levels of active incretins in the body, thereby enhancing insulin secretion and reducing glucagon secretion in a glucose-dependent manner.
  • In summary, DAPAVEL L 10/5MG TABLET 10'S works by a dual mechanism: dapagliflozin promotes glucose excretion through the kidneys, while linagliptin enhances the body's natural ability to regulate blood sugar by increasing incretin activity. This combination helps to effectively lower blood glucose levels in individuals with type 2 diabetes, particularly when diet and exercise alone are not sufficient. It's crucial to take this medication as prescribed by your healthcare provider and to continue following a healthy lifestyle, including a balanced diet and regular physical activity, to achieve optimal blood sugar control. Always consult with your doctor or pharmacist if you have any questions or concerns regarding this medication.

Side Effects of DAPAVEL L 10/5MG TABLET 10'SArrow

Possible side effects of DAPAVEL L 10/5MG TABLET may include: * Hypoglycemia (low blood sugar) * Urinary tract infections (UTIs) * Genital yeast infections (thrush) * Increased urination * Increased thirst * Dizziness * Lightheadedness * Nausea * Constipation * Headache * Upper respiratory tract infection * Back pain * Increased cholesterol levels * Allergic reactions (rash, itching, swelling) * Ketoacidosis (build-up of acid in the blood). Rare but serious. * Fournier's gangrene (a rare but serious infection of the genitals and perineum)

Safety Advice for DAPAVEL L 10/5MG TABLET 10'SArrow

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Allergies

Allergies

Do not use DAPAVEL L 10/5MG TABLET if you are allergic to it.

Dosage of DAPAVEL L 10/5MG TABLET 10'SArrow

  • The recommended dosage of DAPAVEL L 10/5MG TABLET 10'S is typically one tablet daily, taken orally. It is crucial to adhere strictly to your physician's instructions regarding dosage and timing. The tablet should be swallowed whole with a glass of water, and it can be taken with or without food. However, maintaining consistency in how you take the medication each day (either always with food or always without) is advisable for optimal absorption and effect.
  • Your doctor will determine the appropriate dosage based on your individual medical condition, kidney function, other medications you may be taking, and response to treatment. It is essential not to exceed the prescribed dose or discontinue the medication without consulting your healthcare provider. Doing so can lead to undesirable side effects or a worsening of your condition.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up. If you have any concerns or questions regarding your dosage, consult your physician or pharmacist for clarification. Regular monitoring and follow-up appointments with your doctor are important while taking DAPAVEL L 10/5MG TABLET 10'S to assess its effectiveness and adjust the dosage if necessary. Take 'DAPAVEL L 10/5MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DAPAVEL L 10/5MG TABLET 10'S?Arrow

  • If you miss a dose of DAPAVEL L 10/5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store DAPAVEL L 10/5MG TABLET 10'S?Arrow

  • Keep DAPAVEL L 10/5MG TAB 1X10 away from the reach of children and pets.
  • Store DAPAVEL L 10/5MG TAB 1X10 at room temperature.

Benefits of DAPAVEL L 10/5MG TABLET 10'SArrow

  • DAPAVEL L 10/5MG TABLET 10'S is a combination medication specifically designed to manage blood sugar levels in adults diagnosed with type 2 diabetes. It combines two active ingredients: dapagliflozin and linagliptin, each working through different mechanisms to achieve optimal glycemic control. Dapagliflozin belongs to a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors, while linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. This dual action helps to address multiple aspects of type 2 diabetes.
  • One of the primary benefits of DAPAVEL L is its ability to lower blood sugar levels effectively. Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine. This process not only reduces blood sugar but can also lead to modest weight loss, which is beneficial for many individuals with type 2 diabetes who are often overweight or obese. Linagliptin, on the other hand, enhances the levels of incretin hormones in the body. These hormones stimulate the release of insulin when blood sugar is high and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By improving insulin secretion and reducing glucagon, linagliptin helps to regulate blood sugar levels throughout the day, especially after meals.
  • Beyond glycemic control, DAPAVEL L offers additional cardiovascular benefits. Studies have shown that SGLT2 inhibitors like dapagliflozin can reduce the risk of heart failure and cardiovascular death in patients with type 2 diabetes and established cardiovascular disease. This makes DAPAVEL L a valuable option for individuals who need both blood sugar management and heart protection. Furthermore, the medication is generally well-tolerated, with most side effects being mild and manageable. Common side effects associated with dapagliflozin may include urinary tract infections and genital infections due to the increased glucose in the urine. Linagliptin is typically associated with a low risk of hypoglycemia (low blood sugar) when used alone, but caution is advised when combined with other diabetes medications that can lower blood sugar.
  • DAPAVEL L offers a convenient once-daily oral administration, making it easier for patients to adhere to their treatment plan. Its dual mechanism of action provides comprehensive blood sugar control, addressing both fasting and postprandial glucose levels. The added benefits of potential weight loss and cardiovascular protection make it a compelling choice for many individuals with type 2 diabetes. However, it's essential to consult with a healthcare professional to determine if DAPAVEL L is the right medication, considering individual health status, other medications being taken, and potential risks and benefits. Regular monitoring of kidney function and blood sugar levels is recommended while taking DAPAVEL L to ensure its safety and effectiveness.

How to use DAPAVEL L 10/5MG TABLET 10'SArrow

  • DAPAVEL L 10/5MG TABLET 10'S should be taken orally, usually once daily, preferably in the morning. This helps maintain consistent levels of the medication in your body throughout the day. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed.
  • It's important to take DAPAVEL L 10/5MG TABLET 10'S at the same time each day to help you remember and to maintain a steady state of the medication in your system. Consistency is key for optimal results in managing your condition. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • DAPAVEL L 10/5MG TABLET 10'S can be taken with or without food. However, if you experience any stomach upset, taking it with food may help alleviate these symptoms. Follow your doctor's instructions regarding dietary considerations, as certain foods or beverages may interact with the medication.
  • Continue taking DAPAVEL L 10/5MG TABLET 10'S even if you feel well. Many people with diabetes or hypertension don't experience noticeable symptoms, so it's crucial to adhere to your prescribed treatment plan. Do not stop taking the medication without consulting your doctor, as this could lead to a worsening of your condition.
  • Your doctor may adjust your dosage of DAPAVEL L 10/5MG TABLET 10'S based on your individual response to the medication and your overall health status. Regular check-ups and monitoring of your blood sugar levels and blood pressure are essential to ensure the medication is working effectively and to make any necessary adjustments to your treatment plan. Always follow your doctor's specific instructions regarding dosage and administration.
  • Store DAPAVEL L 10/5MG TABLET 10'S at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Properly dispose of any unused medication to prevent accidental ingestion or misuse. Consult your pharmacist or local waste disposal company for information on how to safely dispose of unused medication.

Quick Tips for DAPAVEL L 10/5MG TABLET 10'SArrow

  • Take DAPAVEL L 10/5MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your healthcare provider. Consistent adherence to the prescribed regimen maximizes its effectiveness in managing your blood sugar levels and blood pressure.
  • DAPAVEL L 10/5MG TABLET 10'S is most effective when combined with a healthy lifestyle. Follow a balanced diet low in sugars, saturated fats, and processed foods. Regular physical activity, such as brisk walking, jogging, or swimming, for at least 30 minutes most days of the week can significantly improve your overall health and help manage your conditions more effectively. Consult a nutritionist or a certified fitness trainer for personalized guidance.
  • Monitor your blood sugar and blood pressure levels regularly as advised by your doctor. Keep a record of these measurements and share them with your healthcare provider during your appointments. This helps in assessing the effectiveness of DAPAVEL L 10/5MG TABLET 10'S and allows for timely adjustments to your treatment plan if needed.
  • Be aware of the potential side effects of DAPAVEL L 10/5MG TABLET 10'S, such as dizziness, lightheadedness, or gastrointestinal issues. If you experience any persistent or bothersome side effects, inform your doctor promptly. Do not self-treat; seek medical advice to manage the side effects appropriately.
  • Store DAPAVEL L 10/5MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date before using the medicine and dispose of any expired tablets properly. Proper storage ensures the medication remains effective and safe for use.

Food Interactions with DAPAVEL L 10/5MG TABLET 10'SArrow

  • DAPAVEL L 10/5MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels of the medicine.

FAQs

What is DAPAVEL L 10/5MG TABLET 10'S?Arrow

DAPAVEL L 10/5MG TABLET 10'S is a combination of two medicines: Dapagliflozin and Linagliptin. It is used to control high blood sugar levels in adults with type 2 diabetes.

What is DAPAVEL L 10/5MG TABLET 10'S used for?Arrow

It is used to improve blood sugar levels in adults with type 2 diabetes along with proper diet and exercise.

How does DAPAVEL L 10/5MG TABLET 10'S work?Arrow

Dapagliflozin works by increasing the amount of glucose that is passed out in your urine, while Linagliptin works by increasing the amount of insulin your body produces after a meal.

What are the common side effects of DAPAVEL L 10/5MG TABLET 10'S?Arrow

Common side effects may include genital infections, urinary tract infections, sore throat or runny nose, and diarrhea.

Can DAPAVEL L 10/5MG TABLET 10'S cause kidney problems?Arrow

In rare cases, DAPAVEL L 10/5MG TABLET 10'S can cause kidney problems. It's important to tell your doctor if you have a history of kidney disease.

Can I drink alcohol while taking DAPAVEL L 10/5MG TABLET 10'S?Arrow

It is not recommended to drink alcohol while taking DAPAVEL L 10/5MG TABLET 10'S as it can lower blood sugar levels and increase the risk of side effects.

What happens if I miss a dose of DAPAVEL L 10/5MG TABLET 10'S?Arrow

If you miss a dose of DAPAVEL L 10/5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Is DAPAVEL L 10/5MG TABLET 10'S safe during pregnancy?Arrow

The safety of DAPAVEL L 10/5MG TABLET 10'S during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

How to store DAPAVEL L 10/5MG TABLET 10'S?Arrow

Store DAPAVEL L 10/5MG TABLET 10'S at room temperature, away from heat and moisture. Keep out of reach of children and pets.

Can DAPAVEL L 10/5MG TABLET 10'S interact with other medications?Arrow

DAPAVEL L 10/5MG TABLET 10'S can interact with certain other medications, such as insulin and sulfonylureas. It's important to tell your doctor if you are taking any other medications.

Is DAPAVEL L 10/5MG TABLET 10'S good for heart health?Arrow

Some studies have shown that dapagliflozin may have benefits for heart health, but more research is needed.

Can I take DAPAVEL L 10/5MG TABLET 10'S with Metformin?Arrow

DAPAVEL L 10/5MG TABLET 10'S can be taken with Metformin, but this should be as directed by your doctor.

What dietary precautions should I follow while taking DAPAVEL L 10/5MG TABLET 10'S?Arrow

It is important to eat a balanced diet and be mindful of your carbohydrate intake. Follow any dietary advice given by your doctor or a dietician.

Can I break or chew DAPAVEL L 10/5MG TABLET 10'S?Arrow

DAPAVEL L 10/5MG TABLET 10'S should be swallowed whole, not broken or chewed.

What should I do if I experience severe side effects after taking DAPAVEL L 10/5MG TABLET 10'S?Arrow

If you experience severe side effects after taking DAPAVEL L 10/5MG TABLET 10'S, seek immediate medical attention.

References

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FDA - QTERN (dapagliflozin and saxagliptin) tablets, for oral use. Full prescribing information. Highlights of prescribing information: QTERN contains two oral antihyperglycemic drugs, dapagliflozin and saxagliptin. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor and saxagliptin is a dipeptidyl peptidase-4 (DPP4) inhibitor.

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DrugBank - Dapagliflozin. Dapagliflozin is a selective and reversible inhibitor of sodium-glucose co-transporter 2 (SGLT2), the major transporter involved in renal glucose reabsorption. By inhibiting SGLT2, dapagliflozin reduces renal glucose reabsorption and increases urinary glucose excretion, leading to a reduction in blood glucose levels.

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DrugBank - Linagliptin. Linagliptin is a selective inhibitor of dipeptidyl peptidase-4 (DPP-4), an enzyme that degrades incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By inhibiting DPP-4, linagliptin increases the levels of active incretin hormones, which stimulate insulin release and decrease glucagon secretion in a glucose-dependent manner.

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European Medicines Agency - Xigduo. Xigduo contains dapagliflozin and metformin and is used to treat adults with type 2 diabetes. It can be used on its own in patients who cannot take metformin or together with other diabetes medicines when these do not provide adequate blood sugar control.

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National Center for Biotechnology Information (NCBI) - Efficacy and safety of dapagliflozin as add-on therapy to linagliptin in patients with inadequately controlled type 2 diabetes mellitus: A randomized, double-blind, phase III study

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American Journal of Obstetrics & Gynecology - A randomized trial of metformin and/or linagliptin for the treatment of gestational diabetes (GLITAZONE): An International Multicenter Study

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National Center for Biotechnology Information (NCBI) - Dapagliflozin: A review of its use in the treatment of type 2 diabetes mellitus

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DAPAVEL L 10/5MG TABLET 10'S

DAPAVEL L 10/5MG TABLET 10'S

MRP

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₹158.74

15 % OFF

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