DAXIGA L TABLET 10'S

How DAXIGA L TABLET 10'S Works

• DAXIGA L TABLET 10'S is a combination medication containing dapagliflozin and metformin, each contributing uniquely to its mechanism of action in managing type 2 diabetes. Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin works by selectively inhibiting SGLT2, thereby reducing the reabsorption of glucose and promoting its excretion in the urine. This action lowers blood glucose levels.
• Specifically, when blood glucose levels are high, the kidneys filter more glucose. Dapagliflozin prevents the kidneys from reabsorbing this excess glucose, allowing it to be eliminated through urine. This mechanism is insulin-independent, meaning it works regardless of insulin levels or insulin resistance. As a result, it can be effective even in individuals with impaired insulin function. Additionally, the excretion of glucose in the urine leads to a calorie loss, which can contribute to weight loss.
• Metformin, on the other hand, is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. In the liver, metformin inhibits gluconeogenesis, the process by which glucose is produced from non-carbohydrate sources. By reducing gluconeogenesis, metformin lowers the amount of glucose released into the bloodstream.
• Furthermore, metformin enhances insulin sensitivity in peripheral tissues, such as muscle and fat. This means that cells are more responsive to insulin's signal to take up glucose from the blood. Consequently, more glucose is absorbed by these tissues, further reducing blood glucose levels. Metformin also has a modest effect on reducing glucose absorption from the intestines.
• The combination of dapagliflozin and metformin in DAXIGA L TABLET 10'S offers a dual approach to managing blood glucose levels. Dapagliflozin reduces glucose reabsorption in the kidneys, while metformin decreases glucose production in the liver and improves insulin sensitivity. This synergistic action provides more effective glycemic control compared to either drug used alone. Additionally, the complementary mechanisms can help minimize the risk of side effects associated with high doses of either individual medication. DAXIGA L TABLET 10'S should be used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Common side effects of DAXIGA L Tablet may include: Genital fungal infections (both in men and women), Urinary tract infections (UTIs), Increased urination, Thirst, Nausea, Constipation. Less common but potentially serious side effects may include: Diabetic ketoacidosis (DKA), Kidney problems, Hypoglycemia (low blood sugar, especially when taken with other diabetes medications), Allergic reactions (rash, itching, swelling), Fournier's gangrene (a rare but serious infection of the genitals). Increased cholesterol levels. Serious allergic reaction. This is not an exhaustive list. It's crucial to consult your doctor or pharmacist for a complete list and to report any unusual symptoms while taking DAXIGA L Tablet.

• If you miss a dose of DAXIGA L TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep DAXIGA L TAB 1X10 away from the reach of children and pets.
• Store DAXIGA L TAB 1X10 at room temperature.

• Take DAXIGA L Tablet 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed dosage is crucial for managing your blood sugar levels and preventing potential complications.
• DAXIGA L Tablet 10'S is most effective when taken in conjunction with a healthy diet and regular exercise. Focus on incorporating balanced meals rich in fiber, lean protein, and healthy fats. Engage in at least 30 minutes of moderate-intensity exercise most days of the week to improve insulin sensitivity and overall well-being.
• Stay well-hydrated by drinking plenty of water throughout the day while taking DAXIGA L Tablet 10'S. Adequate hydration supports kidney function and helps to eliminate excess glucose from your body through urine, which is part of how Dapagliflozin works. Aim for at least 8 glasses of water daily.
• Monitor your blood sugar levels regularly as directed by your doctor while on DAXIGA L Tablet 10'S. Keeping track of your blood glucose readings will help you and your healthcare provider assess how well the medication is working and make any necessary adjustments to your treatment plan. Use a reliable blood glucose meter and keep a log of your results.
• Be aware of the potential side effects of DAXIGA L Tablet 10'S, such as urinary tract infections, yeast infections, and dehydration. Contact your doctor immediately if you experience any unusual symptoms or suspect you have a side effect. Prompt medical attention can help prevent complications and ensure your safety.

• Daxiga L Tablet 10'S can be taken with or without food. Food does not significantly affect the absorption of this medication.