DAPASACH MS 10/100/1000MG TABLET 10'S

How DAPASACH MS 10/100/1000MG TABLET 10'S Works

• DAPASACH MS 10/100/1000MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Dapagliflozin, Metformin Hydrochloride (SR), and Sitagliptin. Each component works through a distinct mechanism to achieve comprehensive glycemic control.
• Dapagliflozin belongs to a class of drugs called Sodium-Glucose Co-transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin inhibits SGLT2, reducing glucose reabsorption. This allows excess glucose to be excreted through urine, thereby lowering blood sugar levels. By reducing glucose reabsorption, dapagliflozin also provides a mild diuretic effect, which can contribute to blood pressure reduction and potential weight loss.
• Metformin Hydrochloride (SR) is a biguanide that works primarily by decreasing glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Metformin also enhances insulin sensitivity in peripheral tissues, such as muscles, allowing cells to utilize glucose more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines, further contributing to its blood sugar-lowering effect. The 'SR' designation indicates a sustained-release formulation, which allows for a slower and more gradual release of Metformin, reducing the incidence of gastrointestinal side effects and allowing for once-daily dosing.
• Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that breaks down incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). Incretin hormones stimulate insulin release from the pancreas in response to food intake and also suppress glucagon secretion, a hormone that raises blood sugar. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones, leading to increased insulin release and decreased glucagon secretion, both of which help lower blood glucose levels, especially after meals.
• In summary, DAPASACH MS works through three complementary mechanisms: Dapagliflozin eliminates excess glucose via the kidneys, Metformin reduces glucose production in the liver and enhances insulin sensitivity, and Sitagliptin increases insulin release and reduces glucagon secretion. This triple-action approach provides comprehensive glycemic control in patients with type 2 diabetes, addressing multiple aspects of the disease's pathophysiology. It is important to take this medication as prescribed by your doctor and to follow dietary and exercise recommendations for optimal results.

Common side effects of DAPASACH MS 10/100/1000MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, and fatigue. Less common but potentially serious side effects can include peripheral neuropathy (numbness, tingling, or pain in the hands and feet), liver problems (such as elevated liver enzymes or jaundice), kidney problems, lactic acidosis (a buildup of lactic acid in the body), pancreatitis, and allergic reactions (rash, itching, swelling, or difficulty breathing). Changes in blood sugar levels (both hypoglycemia and hyperglycemia) may also occur. Some patients may experience skin reactions, such as photosensitivity or Stevens-Johnson syndrome (a severe skin rash). Musculoskeletal issues like muscle pain or weakness have also been reported. It's important to contact your doctor immediately if you experience any unusual or severe symptoms while taking this medication.

• If you miss a dose of DAPASACH MS 10/100/1000MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep DAPASACH MS 10/100/1000MG TAB 1X10 away from the reach of children and pets.
• Store DAPASACH MS 10/100/1000MG TAB 1X10 at room temperature.

• Take DAPASACH MS exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures the medication works effectively and minimizes potential side effects. It's crucial for maintaining stable blood sugar levels.
• DAPASACH MS should be taken with food, preferably with your first main meal of the day. This helps to reduce stomach upset and improves the absorption of the medication. Consistent timing with meals maximizes its benefit in controlling blood sugar.
• Regularly monitor your blood sugar levels while taking DAPASACH MS. Keep a log of your readings and share them with your healthcare provider. This helps them to adjust your dosage if needed and ensures optimal blood sugar control. This also helps you understand how your body is responding to the medication.
• Stay well-hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function, which is important when taking medications like DAPASACH MS. Dehydration can exacerbate side effects and impact overall health.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Some substances can interact with DAPASACH MS, potentially affecting its efficacy or increasing the risk of side effects. A complete medication list ensures your doctor can manage your treatment safely.
• Follow a balanced diet and engage in regular physical activity. DAPASACH MS works best when combined with a healthy lifestyle. A proper diet and exercise regimen can significantly improve blood sugar control and overall well-being. Consult a dietitian or certified trainer for personalized guidance.

• DAPASACH MS 10/100/1000MG TABLET 10'S is generally safe to take with or without food. However, it's best to take it at a consistent time each day to maintain stable blood sugar levels. If you experience any stomach upset, taking it with food may help. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of side effects and interfere with blood sugar control. Consult your doctor or pharmacist for personalized advice based on your individual health condition and dietary habits.