SITAGLYN DM 100/1000MG TABLET 10'S

How SITAGLYN DM 100/1000MG TABLET 10'S Works

• SITAGLYN DM 100/1000MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: sitagliptin and metformin, each working through different mechanisms to achieve optimal glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar levels. They stimulate insulin release from the pancreas when blood sugar is high and reduce glucagon secretion from the liver, which decreases glucose production. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This leads to enhanced insulin secretion in response to meals and reduced glucagon secretion, ultimately lowering blood sugar levels.
• Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver. The liver is a major source of glucose in the body, and in individuals with type 2 diabetes, it often produces excessive amounts of glucose, contributing to high blood sugar levels. Metformin suppresses this hepatic glucose production through several mechanisms, including inhibiting gluconeogenesis (the process of making glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose).
• Additionally, metformin improves insulin sensitivity in peripheral tissues, such as muscles. This means that the body's cells become more responsive to insulin, allowing them to take up glucose from the bloodstream more effectively. This increased glucose uptake further helps to lower blood sugar levels. Metformin also slows down the absorption of glucose from the intestines after a meal, which can help prevent spikes in blood sugar levels.
• The combination of sitagliptin and metformin in SITAGLYN DM 100/1000MG TABLET 10'S provides a dual-action approach to managing blood sugar. Sitagliptin enhances insulin secretion and reduces glucagon secretion, while metformin reduces hepatic glucose production, improves insulin sensitivity, and slows down glucose absorption. This synergistic effect helps to achieve better glycemic control than either medication alone.
• In summary, SITAGLYN DM 100/1000MG TABLET 10'S works by: 1. Increasing incretin hormone levels, leading to enhanced insulin release and reduced glucagon secretion (sitagliptin). 2. Decreasing glucose production in the liver (metformin). 3. Improving insulin sensitivity in peripheral tissues (metformin). 4. Slowing down glucose absorption from the intestines (metformin). These combined actions help to lower blood sugar levels and improve overall glycemic control in individuals with type 2 diabetes.

The following side effects may occur while taking SITAGLYN DM 100/1000MG TABLET. Common side effects include nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are upper respiratory tract infection, headache, and allergic reactions such as rash, itching, or hives. In rare cases, serious side effects like pancreatitis, severe joint pain, kidney problems, and lactic acidosis may occur. Contact your doctor immediately if you experience persistent or severe side effects.

• If you miss a dose of SITAGLYN DM 100/1000MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep SITAGLYN DM 100/1000MG TAB 1X10 away from the reach of children and pets.
• Store SITAGLYN DM 100/1000MG TAB 1X10 at room temperature.

• Take SITAGLYN DM 100/1000MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this can affect your blood sugar levels.
• It is best to take SITAGLYN DM 100/1000MG TABLET 10'S with food to help prevent stomach upset. Swallow the tablet whole with a glass of water, and do not crush or chew it.
• Regularly monitor your blood sugar levels as directed by your doctor while taking SITAGLYN DM 100/1000MG TABLET 10'S. Keep a record of your blood sugar readings to share with your healthcare provider during your check-ups. This information helps them adjust your treatment plan as needed.
• SITAGLYN DM 100/1000MG TABLET 10'S can cause low blood sugar (hypoglycemia), especially when taken with other diabetes medications or insulin. Be aware of the symptoms of low blood sugar, such as sweating, shaking, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times to treat hypoglycemia.
• Maintain a healthy lifestyle by following a balanced diet and getting regular exercise. These habits, along with SITAGLYN DM 100/1000MG TABLET 10'S, can help you manage your blood sugar levels effectively. Talk to your doctor or a registered dietitian for guidance on meal planning and exercise routines suitable for you.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports overall health and helps your kidneys function properly, which is important when taking medications like SITAGLYN DM 100/1000MG TABLET 10'S.
• Inform your doctor about all the other medications, supplements, and herbal products you are taking. Some medications can interact with SITAGLYN DM 100/1000MG TABLET 10'S and affect its effectiveness or increase the risk of side effects.
• If you experience any persistent or bothersome side effects, such as nausea, vomiting, diarrhea, or abdominal pain, consult your doctor promptly. They can assess your condition and recommend appropriate management strategies.
• Attend all scheduled appointments with your doctor and undergo regular check-ups, including blood tests to monitor your kidney function and other relevant health parameters. These evaluations help ensure that SITAGLYN DM 100/1000MG TABLET 10'S is working effectively and safely for you.
• Store SITAGLYN DM 100/1000MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Properly dispose of any expired or unused medication according to local regulations.

• SITAGLYN DM 100/1000MG TABLET 10'S can be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood sugar levels. If you experience nausea or stomach upset, taking it with food may help. Avoid excessive alcohol consumption as it can increase the risk of low blood sugar (hypoglycemia).