SITACIP DM 100/10/1000MG TABLET 10'S
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SITACIP DM 100/10/1000MG TABLET 10'S
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SITACIP DM 100/10/1000MG TABLET 10'S

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SITACIP DM 100/10/1000MG TABLET 10'S

By CIPLA PHARMACEUTICAL COMPANY LIMITED

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242

₹205.7

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About SITACIP DM 100/10/1000MG TABLET 10'S

  • SITACIP DM 100/10/1000MG TABLET 10'S is a combination medication meticulously formulated to manage blood sugar levels in adults diagnosed with type 2 diabetes. This powerful combination therapy incorporates three active ingredients: Sitagliptin, Dapagliflozin, and Metformin.
  • Sitagliptin belongs to a class of drugs known as DPP-4 inhibitors. It functions by enhancing the levels of incretin hormones, which play a crucial role in regulating blood sugar. By increasing incretin levels, Sitagliptin stimulates insulin release after meals and reduces the amount of sugar produced by the liver.
  • Dapagliflozin is an SGLT2 inhibitor. It works by preventing the kidneys from reabsorbing glucose back into the bloodstream. Instead, the excess glucose is eliminated from the body through urine, effectively lowering blood sugar levels.
  • Metformin is a biguanide that decreases glucose production in the liver, reduces glucose absorption in the intestines, and improves insulin sensitivity. It's a cornerstone medication in the treatment of type 2 diabetes, often prescribed as a first-line therapy.
  • This triple combination offers a comprehensive approach to managing blood sugar levels, targeting multiple pathways involved in glucose regulation. It is typically prescribed when diet, exercise, and single or dual therapy with other diabetes medications are insufficient to achieve adequate glycemic control. SITACIP DM helps to lower A1C (average blood sugar levels) and also helps to prevent complications associated with diabetes.
  • Always take SITACIP DM 100/10/1000MG TABLET 10'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. It is important to adhere to your prescribed diet and exercise regimen while taking this medication to maximize its effectiveness. Regular monitoring of blood sugar levels is also essential to ensure optimal management of your diabetes.

Uses of SITACIP DM 100/10/1000MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Controlling high blood sugar levels
  • Improving blood sugar control
  • Increasing insulin sensitivity
  • Lowering post-meal blood sugar levels
  • Preventing kidney damage
  • Preventing blindness
  • Preventing nerve problems
  • Preventing loss of limbs
  • Preventing heart disease

How SITACIP DM 100/10/1000MG TABLET 10'S Works

  • SITACIP DM 100/10/1000MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: Sitagliptin, Dapagliflozin, and Metformin. Each component works through different mechanisms to lower blood sugar levels and improve glycemic control.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood sugar is high and reduce glucagon secretion from the liver when blood sugar is low. By inhibiting DPP-4, Sitagliptin increases the levels of active incretins in the body. This results in enhanced insulin secretion in response to elevated blood glucose and reduced glucagon secretion, ultimately lowering blood sugar levels. Sitagliptin's action is glucose-dependent, meaning it primarily works when blood sugar is high, reducing the risk of hypoglycemia (low blood sugar).
  • Dapagliflozin is an SGLT2 inhibitor (sodium-glucose cotransporter-2 inhibitor). SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. By blocking SGLT2, Dapagliflozin prevents the kidneys from reabsorbing glucose, causing excess glucose to be excreted in the urine. This lowers blood sugar levels and can also lead to weight loss as calories are lost through the urine. Dapagliflozin also offers cardiovascular benefits by reducing blood pressure and improving heart function in some patients with type 2 diabetes.
  • Metformin is a biguanide that works primarily by reducing glucose production in the liver. It also improves insulin sensitivity in the body's tissues, allowing cells to use glucose more effectively. Metformin decreases the amount of glucose absorbed from the intestines and enhances glucose uptake and utilization in peripheral tissues like muscles. Unlike some other diabetes medications, Metformin does not stimulate insulin release, so it carries a lower risk of causing hypoglycemia when used alone. Metformin is often the first-line treatment for type 2 diabetes due to its effectiveness, safety, and potential cardiovascular benefits.
  • In summary, SITACIP DM 100/10/1000MG TABLET 10'S works by combining the complementary actions of Sitagliptin, Dapagliflozin, and Metformin. Sitagliptin enhances insulin secretion and reduces glucagon secretion, Dapagliflozin promotes glucose excretion through the kidneys, and Metformin reduces glucose production in the liver and improves insulin sensitivity. This triple combination approach helps to effectively manage blood sugar levels in people with type 2 diabetes, improving their overall health and reducing the risk of diabetes-related complications. It is essential to take this medication as prescribed by your healthcare provider and to follow a healthy diet and exercise plan for optimal results.

Side Effects of SITACIP DM 100/10/1000MG TABLET 10'SArrow

Possible side effects of SITACIP DM 100/10/1000MG Tablet may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, hypoglycemia (low blood sugar), skin rash, itching. * **Uncommon:** Constipation, flatulence, dizziness, drowsiness, weakness, upper respiratory tract infection, blurred vision, increased sweating. * **Rare:** Severe allergic reactions (anaphylaxis), pancreatitis, liver problems (hepatitis), kidney problems, lactic acidosis (build-up of lactic acid in the blood), Stevens-Johnson syndrome (severe skin reaction), decreased Vitamin B12 absorption, joint pain, muscle pain. This is not an exhaustive list, and other side effects may occur. If you experience any unusual symptoms while taking this medication, consult your doctor immediately.

Safety Advice for SITACIP DM 100/10/1000MG TABLET 10'SArrow

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Allergies

Consult a Doctor

Do not use Sitacip DM 100/10/1000MG TABLET if you are allergic to sitagliptin, metformin or any of the ingredients in this medicine.

Dosage of SITACIP DM 100/10/1000MG TABLET 10'SArrow

  • The recommended dosage of SITACIP DM 100/10/1000MG TABLET 10'S varies depending on individual patient needs, pre-existing medical conditions, and response to treatment. It is crucial to adhere strictly to the dosage prescribed by your healthcare provider. The usual starting dose is one tablet taken orally once or twice daily, typically with meals to help reduce gastrointestinal side effects. Your doctor may adjust the dosage gradually based on your blood glucose levels and overall health.
  • The maximum daily dose of SITACIP DM 100/10/1000MG TABLET 10'S should not exceed the amounts specified by your doctor. It is important to maintain a consistent schedule for taking your medication, ideally at the same time(s) each day, to optimize its effectiveness. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
  • SITACIP DM 100/10/1000MG TABLET 10'S is typically prescribed as part of a comprehensive diabetes management plan that includes diet and exercise. Continue to follow your diet and exercise recommendations as advised by your doctor or dietician. Regular monitoring of blood glucose levels is essential to assess your response to SITACIP DM 100/10/1000MG TABLET 10'S and to guide dosage adjustments. Take 'SITACIP DM 100/10/1000MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of SITACIP DM 100/10/1000MG TABLET 10'S?Arrow

  • If you miss a dose of SITACIP DM 100/10/1000MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store SITACIP DM 100/10/1000MG TABLET 10'S?Arrow

  • Keep SITACIP DM 100/10/1000MG TAB 1X10 away from the reach of children and pets.
  • Store SITACIP DM 100/10/1000MG TAB 1X10 at room temperature.

Benefits of SITACIP DM 100/10/1000MG TABLET 10'SArrow

  • SITACIP DM 100/10/1000MG TABLET 10'S is a combination medication designed to effectively manage type 2 diabetes. It combines three active ingredients – Sitagliptin, Dapagliflozin and Metformin – each working through different mechanisms to control blood sugar levels. This comprehensive approach offers multiple benefits for individuals with type 2 diabetes.
  • One of the primary benefits of SITACIP DM is its ability to lower HbA1c levels. HbA1c is a measure of average blood sugar control over the past 2-3 months. By targeting multiple pathways involved in glucose regulation, SITACIP DM helps to achieve and maintain better glycemic control, reducing the risk of long-term complications associated with diabetes, such as nerve damage, kidney disease, and vision problems.
  • Sitagliptin, a DPP-4 inhibitor, enhances the incretin system, which naturally stimulates insulin release after meals and reduces glucagon secretion (a hormone that raises blood sugar). Dapagliflozin, an SGLT2 inhibitor, works by preventing the kidneys from reabsorbing glucose back into the blood, leading to excess glucose being eliminated through urine. Metformin, a biguanide, decreases glucose production in the liver and improves insulin sensitivity.
  • Beyond blood sugar control, SITACIP DM may offer additional benefits. Dapagliflozin has been shown to promote weight loss in some individuals, which can be beneficial for overweight or obese patients with type 2 diabetes. Furthermore, some studies suggest that SGLT2 inhibitors like Dapagliflozin may have cardiovascular benefits, reducing the risk of heart failure and other cardiovascular events. Metformin has also been associated with improvements in cholesterol levels.
  • SITACIP DM's triple-action formula can simplify diabetes management. Instead of taking multiple pills throughout the day, patients can often achieve better blood sugar control with a single combination tablet, which can improve adherence to treatment. Its efficacy in controlling blood sugar, potential weight loss benefits, possible cardiovascular protection, and convenience of dosage make SITACIP DM 100/10/1000MG TABLET 10'S an important option for managing type 2 diabetes, always under the guidance of a healthcare professional. Always consult your doctor to determine if SITACIP DM is right for you, considering your overall health condition and other medications you may be taking.

How to use SITACIP DM 100/10/1000MG TABLET 10'SArrow

  • SITACIP DM 100/10/1000MG TABLET 10'S is an oral medication used to manage type 2 diabetes. It combines three active ingredients: Sitagliptin, Dapagliflozin and Metformin. Always adhere to your doctor's instructions regarding dosage and timing.
  • This medication is typically taken once or twice daily with meals to minimize gastrointestinal side effects associated with metformin. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system.
  • Consistency is key. Try to take SITACIP DM at the same time(s) each day to maintain stable blood sugar levels. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Your doctor will likely start you on a low dose of SITACIP DM and gradually increase it based on your blood sugar levels and tolerance to the medication. It's crucial to monitor your blood sugar regularly as directed by your healthcare provider and report any unusual symptoms or side effects.
  • SITACIP DM is most effective when combined with a healthy diet and regular exercise. Follow your doctor's or a registered dietitian's recommendations for a diabetic-friendly meal plan, and aim for at least 30 minutes of moderate-intensity exercise most days of the week. Store SITACIP DM at room temperature, away from moisture and heat, and keep it out of reach of children.
  • Before starting SITACIP DM, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Also, disclose any existing medical conditions, especially kidney or liver problems, heart failure, or a history of pancreatitis. This information is crucial to ensure the safe and effective use of SITACIP DM.
  • Be aware of potential side effects, such as nausea, vomiting, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). If you experience any severe or persistent side effects, contact your doctor immediately. It is also important to stay hydrated while taking this medication, especially during hot weather or intense physical activity. Report any signs of dehydration to your physician.

Quick Tips for SITACIP DM 100/10/1000MG TABLET 10'SArrow

  • Take SITACIP DM 100/10/1000MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your physician. This medication is typically taken orally, usually once or twice daily with meals to help reduce stomach upset and aid in better absorption. Consistency is key; try to take it at the same time(s) each day to maintain steady blood sugar levels. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Never double up on doses to compensate for a missed one.
  • Before starting SITACIP DM 100/10/1000MG TABLET 10'S, inform your doctor about any pre-existing medical conditions you have, especially kidney or liver problems, heart issues, or a history of pancreatitis. Also, disclose all other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, as interactions can occur. Pay close attention to any potential side effects, such as nausea, vomiting, diarrhea, or abdominal pain. If you experience persistent or severe side effects, seek medical attention promptly. Regular monitoring of kidney function and blood sugar levels is essential while on this medication.
  • While taking SITACIP DM 100/10/1000MG TABLET 10'S, it's crucial to adhere to a healthy lifestyle. This includes following a balanced diet low in sugars and refined carbohydrates, engaging in regular physical activity, and maintaining a healthy weight. These lifestyle modifications can significantly improve blood sugar control and overall health. Avoid excessive alcohol consumption, as it can interfere with the medication's effectiveness and increase the risk of side effects. Stay hydrated by drinking plenty of water throughout the day.
  • Be aware of the signs and symptoms of both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). Hypoglycemia symptoms may include shakiness, sweating, dizziness, confusion, and rapid heartbeat. If you experience these symptoms, consume a quick source of sugar, such as fruit juice, honey, or glucose tablets, and check your blood sugar levels. Hyperglycemia symptoms may include increased thirst, frequent urination, blurred vision, and fatigue. If you experience these symptoms, contact your doctor for guidance on adjusting your medication or treatment plan. Always carry a form of identification indicating that you have diabetes and a list of your medications.
  • Store SITACIP DM 100/10/1000MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Regularly check the expiration date and discard any expired medication properly. Do not flush medications down the toilet or pour them down the drain unless instructed to do so. Consult your pharmacist or local waste disposal company for proper disposal methods. If you have any questions or concerns about your medication, do not hesitate to ask your doctor or pharmacist.

Food Interactions with SITACIP DM 100/10/1000MG TABLET 10'SArrow

  • SITACIP DM 100/10/1000MG TABLET 10'S can generally be taken with or without food. However, it is recommended to take it at the same time each day to maintain consistent blood sugar levels. If you experience stomach upset, taking it with food may help. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of low blood sugar (hypoglycemia) and other side effects. Consult your doctor or pharmacist for specific dietary advice related to your condition and medication.

FAQs

What is the use of Sitacip DM 100/10/1000mg Tablet?Arrow

Sitacip DM 100/10/1000mg Tablet is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

What are the active ingredients in Sitacip DM 100/10/1000mg Tablet?Arrow

Sitacip DM 100/10/1000mg Tablet contains Sitagliptin, Dapagliflozin, and Metformin.

What are the common side effects of Sitacip DM 100/10/1000mg Tablet?Arrow

Common side effects of Sitacip DM 100/10/1000mg Tablet include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is Sitacip DM 100/10/1000mg Tablet safe for patients with kidney problems?Arrow

Patients with kidney problems should use Sitacip DM 100/10/1000mg Tablet with caution and consult a doctor.

How should I store Sitacip DM 100/10/1000mg Tablet?Arrow

Store Sitacip DM 100/10/1000mg Tablet at room temperature, away from direct sunlight and moisture.

Should Sitacip DM 100/10/1000mg Tablet be taken with food?Arrow

Sitacip DM 100/10/1000mg Tablet can be taken with or without food, but it is best to take it at the same time each day.

What happens if I miss a dose of Sitacip DM 100/10/1000mg Tablet?Arrow

If you miss a dose of Sitacip DM 100/10/1000mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can Sitacip DM 100/10/1000mg Tablet interact with other medications?Arrow

Sitacip DM 100/10/1000mg Tablet can interact with certain medications. Therefore, it is important to tell your doctor about all the medications you are taking.

Is Sitacip DM 100/10/1000mg Tablet safe for pregnant women?Arrow

The safety of Sitacip DM 100/10/1000mg Tablet for pregnant women has not been established. Therefore, it is important to consult a doctor before using it during pregnancy.

Is Sitacip DM 100/10/1000mg Tablet safe for breastfeeding women?Arrow

It is not known whether Sitacip DM 100/10/1000mg Tablet is excreted in breast milk. Therefore, it is important to consult a doctor before using it during breastfeeding.

What are the symptoms of an overdose of Sitacip DM 100/10/1000mg Tablet?Arrow

Symptoms of an overdose of Sitacip DM 100/10/1000mg Tablet may include nausea, vomiting, stomach pain, diarrhea, and hypoglycemia (low blood sugar).

What should I do if I overdose on Sitacip DM 100/10/1000mg Tablet?Arrow

If you overdose on Sitacip DM 100/10/1000mg Tablet, seek immediate medical attention.

Can I drink alcohol while taking Sitacip DM 100/10/1000mg Tablet?Arrow

You should avoid drinking alcohol while taking Sitacip DM 100/10/1000mg Tablet, as it may increase the risk of hypoglycemia.

How long does it take for Sitacip DM 100/10/1000mg Tablet to work?Arrow

It may take a few days for Sitacip DM 100/10/1000mg Tablet to start lowering blood sugar levels.

Does Sitacip DM 100/10/1000mg Tablet cause weight gain?Arrow

Sitacip DM 100/10/1000mg Tablet is less likely to cause weight gain, but it can happen in some individuals.

References

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FDA - JANUVIA (sitagliptin) tablets - Medical Review(see section on Clinical Pharmacology for Sitagliptin)

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DrugBank - Sitagliptin

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FDA - Metformin Hydrochloride Label (see Clinical Pharmacology section for Metformin)

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DrugBank - Metformin

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European Medicines Agency - Velmetia (sitagliptin / metformin hydrochloride)

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PubMed - Search for Sitagliptin and Metformin clinical trials and research

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SITACIP DM 100/10/1000MG TABLET 10'S

SITACIP DM 100/10/1000MG TABLET 10'S

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₹205.7

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