SITANORM DM 1000 TABLET 15'S

How SITANORM DM 1000 TABLET 15'S Works

• SITANORM DM 1000 TABLET 15'S is a combination medication containing Sitagliptin and Metformin. It is prescribed to manage blood sugar levels in adults with type 2 diabetes, especially when diet and exercise alone are not sufficient. To understand how SITANORM DM 1000 works, it's essential to consider the individual actions of its two active ingredients: Sitagliptin and Metformin.
• **Sitagliptin:** Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar levels. They stimulate insulin release from the pancreas when blood sugar is high and reduce glucagon secretion (a hormone that raises blood sugar) from the liver. Sitagliptin works by inhibiting the DPP-4 enzyme, which prevents the breakdown of incretin hormones. This, in turn, increases the levels of active incretin hormones in the body. As a result, there is enhanced insulin secretion when blood sugar is elevated and reduced glucagon secretion, leading to better blood sugar control.
• **Metformin:** Metformin is a biguanide and works through several mechanisms to lower blood sugar levels. Firstly, it decreases glucose production in the liver by suppressing hepatic gluconeogenesis (the process by which the liver produces glucose). Secondly, Metformin increases insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. This means that the body's cells become more responsive to insulin, facilitating glucose uptake from the bloodstream. Thirdly, Metformin slows down the absorption of glucose from the intestines after a meal, which helps to prevent rapid spikes in blood sugar levels after eating.
• **Synergistic Effect:** When Sitagliptin and Metformin are combined in SITANORM DM 1000, they work synergistically to provide comprehensive blood sugar control. Sitagliptin enhances insulin secretion and reduces glucagon secretion, while Metformin reduces glucose production in the liver, improves insulin sensitivity, and slows down glucose absorption. This combined action helps to lower both fasting and postprandial (after-meal) blood sugar levels. It's important to note that SITANORM DM 1000 is most effective when used in conjunction with a healthy diet and regular exercise. It is also essential to follow your doctor's instructions carefully regarding dosage and timing of medication. Regular monitoring of blood sugar levels is necessary to assess the effectiveness of the treatment and make any necessary adjustments.
• In summary, SITANORM DM 1000 effectively manages type 2 diabetes by utilizing the complementary actions of Sitagliptin to enhance incretin activity and Metformin to reduce glucose production and improve insulin sensitivity, leading to balanced and controlled blood sugar levels.

SITANORM DM 1000 TABLET 15'S may cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, and metallic taste in the mouth. Less common but potentially serious side effects include lactic acidosis (symptoms include feeling cold, dizziness, muscle pain, severe drowsiness, slow or irregular heartbeat, and trouble breathing), pancreatitis (severe abdominal pain that may radiate to your back), and allergic reactions (rash, itching, swelling, and difficulty breathing). Other possible side effects are hypoglycemia (low blood sugar) when used with other diabetes medications, and vitamin B12 deficiency with long-term use, leading to symptoms like fatigue, weakness, and neurological problems. Consult your doctor if you experience any persistent or severe side effects.

• If you miss a dose of SITANORM DM 1000 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITANORM DM 1000MG TAB 1X15 away from the reach of children and pets.
• Store SITANORM DM 1000MG TAB 1X15 at room temperature.

• Take SITANORM DM 1000 TABLET 15'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a full glass of water, preferably with meals to reduce gastrointestinal side effects. Consistent timing helps maintain stable blood sugar levels.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. Keep a record of your readings and share them with your doctor during appointments. This helps in assessing the effectiveness of the medication and making necessary adjustments to your treatment plan.
• Follow a balanced diet and engage in regular physical activity while taking SITANORM DM 1000 TABLET 15'S. A healthy diet rich in fiber, fruits, and vegetables, combined with at least 30 minutes of moderate-intensity exercise most days of the week, can significantly improve blood sugar control.
• Be aware of the symptoms of hypoglycemia (low blood sugar) such as shakiness, sweating, dizziness, and confusion. Carry a source of fast-acting glucose, like glucose tablets or fruit juice, with you at all times to treat hypoglycemia promptly. Inform your family and friends about how to recognize and treat hypoglycemia.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Some medications can interact with SITANORM DM 1000 TABLET 15'S, affecting its efficacy or increasing the risk of side effects. It is especially important to mention any medications for high blood pressure, heart conditions, or kidney problems.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function and helps in the excretion of excess glucose. Limit your intake of sugary beverages and alcohol, as they can negatively impact blood sugar levels.
• Attend all scheduled appointments with your doctor and undergo regular check-ups, including blood tests and kidney function tests. These tests help in monitoring your overall health and detecting any potential complications early. Adherence to follow-up appointments is crucial for effective diabetes management.

• SITANORM DM 1000 TABLET 15'S can be taken with or without food, as food does not significantly affect its absorption or effectiveness. However, taking it with food might help reduce potential gastrointestinal side effects like nausea or stomach upset.