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ISTAMET D XR 1000MG TABLET 7'S

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ISTAMET D XR 1000MG TABLET 7'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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168

₹142.8

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About ISTAMET D XR 1000MG TABLET 7'S

  • Istamet D XR 1000 mg Tablet is a three-drug combination medicine used to treat type 2 diabetes mellitus. It combines dapagliflozin 10 mg, metformin hydrochloride 1000 mg (sustained release), and sitagliptin 100 mg, and helps control blood sugar in adults when diet and exercise alone — or fewer medicines — are not sufficient. The three ingredients lower glucose through three complementary mechanisms.
  • Metformin is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues, allowing better glucose uptake. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the levels of incretin hormones, which help regulate blood sugar by increasing insulin release after a meal and decreasing the glucose produced by the liver. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works in the kidneys to remove excess glucose from the body through the urine, lowering blood sugar independently of insulin and often supporting modest weight and blood-pressure reduction.
  • Istamet D XR is an extended-release formulation, meaning it releases the medicine slowly over time, helping maintain stable blood sugar through the day and often reducing how often it needs to be taken; it is typically taken once daily, preferably with the evening meal. By addressing liver glucose production, insulin release, and glucose removal by the kidneys together, this triple combination offers comprehensive glycaemic control.
  • It is important to use Istamet D XR alongside a healthy diet and regular exercise for the best results, and to monitor your blood sugar regularly to assess how well it is working and guide any adjustments. Always consult your doctor to determine whether it is right for you, and discuss your complete medical history and all other medicines you take before starting.
  • Common side effects may include nausea, diarrhoea, stomach upset, and headache; because of the SGLT2 component, genital and urinary tract infections can occur, so stay well hydrated and maintain good hygiene. A rare but serious condition called diabetic ketoacidosis is possible, so seek urgent medical care for symptoms such as severe stomach pain, vomiting, difficulty breathing, or unusual drowsiness, and tell your doctor about any kidney or liver problems, as kidney function may be checked before and during treatment.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Istamet D XR 1000mg Tablet 7's that is Dapagliflozin 10 Mg+metformin Hydrochloride 1000 MG Sustained Release+sitagliptin 100 MG. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of ISTAMET D XR 1000MG TABLET 7'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Aiding in blood sugar control
  • Management of insulin resistance associated with polycystic ovary syndrome (PCOS) (off-label use)

How ISTAMET D XR 1000MG TABLET 7'S Works

  • ISTAMET D XR 1000MG TABLET 7'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: metformin and a dipeptidyl peptidase-4 (DPP-4) inhibitor. Each component works through different mechanisms to achieve better glycemic control.
  • Metformin, the primary ingredient, primarily works by decreasing glucose production in the liver. It reduces hepatic gluconeogenesis, which is the process by which the liver converts non-carbohydrate sources into glucose. By inhibiting this process, metformin lowers the amount of glucose released into the bloodstream, particularly during fasting periods and overnight. Metformin also enhances insulin sensitivity in peripheral tissues, such as muscles and fat. This means that cells become more responsive to insulin, allowing them to uptake glucose more efficiently from the blood. This improved insulin sensitivity further contributes to lower blood sugar levels, especially after meals. Additionally, Metformin slows down the absorption of glucose from the intestines into the bloodstream, reducing the postprandial (after-meal) glucose spike. This helps in maintaining stable blood sugar levels throughout the day. The 'XR' in ISTAMET D XR stands for extended-release, meaning that the medication is released slowly into the body over a longer period, providing a more consistent effect and reducing the frequency of dosage.
  • The DPP-4 inhibitor component in ISTAMET D XR works by increasing the levels of incretin hormones in the body. Incretins, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released from the intestines in response to food intake. These hormones stimulate insulin release from the pancreas in a glucose-dependent manner, meaning that insulin is released only when blood sugar levels are high. They also suppress glucagon secretion, a hormone that raises blood sugar levels. By inhibiting DPP-4, the enzyme that breaks down incretin hormones, ISTAMET D XR prolongs the action of GLP-1 and GIP. This leads to increased insulin secretion, decreased glucagon secretion, and ultimately, better blood sugar control, particularly after meals. The combined effect of metformin reducing glucose production and improving insulin sensitivity, along with the DPP-4 inhibitor enhancing incretin activity, results in a synergistic action that effectively lowers blood sugar levels in individuals with type 2 diabetes. Regular monitoring of blood sugar levels and adherence to a healthy diet and exercise plan are crucial for optimizing the benefits of ISTAMET D XR 1000MG TABLET 7'S.

Side Effects of ISTAMET D XR 1000MG TABLET 7'SArrow

The following side effects may occur while using ISTAMET D XR 1000MG TABLET 7'S. It is important to consult your doctor if you experience any of these or other concerning symptoms: **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Headache * Weakness **Uncommon Side Effects:** * Hypoglycemia (low blood sugar) * Skin rash or itching * Dizziness * Constipation * Gas * Heartburn **Rare and Serious Side Effects (Seek immediate medical attention):** * Lactic acidosis (symptoms may include feeling very weak, tired or uncomfortable; unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat) * Vitamin B12 deficiency * Liver problems (symptoms may include persistent nausea/vomiting, severe abdominal pain, yellowing eyes/skin, dark urine) * Pancreatitis (severe stomach pain radiating to the back, with nausea and vomiting) * Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)

Safety Advice for ISTAMET D XR 1000MG TABLET 7'SArrow

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Allergies

Allergies

Do not use ISTAMET D XR 1000MG TABLET 7'S if you are allergic to it.

Dosage of ISTAMET D XR 1000MG TABLET 7'SArrow

  • The recommended dosage of ISTAMET D XR 1000MG TABLET 7'S varies depending on individual patient needs, pre-existing medical conditions, and response to treatment. It's crucial to adhere strictly to your physician's prescribed dosage and schedule. Typically, ISTAMET D XR is taken once daily, preferably with the evening meal to minimize gastrointestinal side effects associated with metformin.
  • The starting dose is usually one tablet daily. Your doctor may gradually increase the dosage every 1-2 weeks based on your blood glucose levels and tolerance. The maximum recommended daily dose is generally two tablets (2000mg) taken together once daily.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect the extended-release mechanism and lead to rapid release of the medication, potentially causing adverse effects.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It is important to monitor your blood glucose levels regularly as directed by your healthcare provider while taking ISTAMET D XR. This will help your doctor adjust your dosage as needed to achieve optimal blood glucose control.
  • Take 'ISTAMET D XR 1000MG TABLET 7'S' only as per the prescription by your physician only

What if I miss my dose of ISTAMET D XR 1000MG TABLET 7'S?Arrow

  • If you miss a dose of ISTAMET D XR 1000MG TABLET 7'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store ISTAMET D XR 1000MG TABLET 7'S?Arrow

  • Keep ISTAMET D XR 1000MG TAB 1X7 away from the reach of children and pets.
  • Store ISTAMET D XR 1000MG TAB 1X7 at room temperature.

Benefits of ISTAMET D XR 1000MG TABLET 7'SArrow

  • ISTAMET D XR 1000MG TABLET 7'S offers a dual-action approach to managing type 2 diabetes by combining the benefits of metformin and a DPP-4 inhibitor. This combination helps to control blood sugar levels more effectively than either medication alone. Metformin primarily works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues, allowing cells to utilize glucose more efficiently. The DPP-4 inhibitor enhances the body's own ability to lower blood sugar by increasing the levels of incretin hormones, which stimulate insulin release and reduce glucagon secretion, particularly after meals.
  • The extended-release (XR) formulation of ISTAMET D XR 1000MG TABLET 7'S provides a steady release of medication throughout the day, which helps to maintain stable blood sugar levels and reduce the risk of sudden spikes or drops. This can lead to better overall glycemic control and a decreased need for frequent blood sugar monitoring. The once-daily dosing also improves convenience and adherence to the medication regimen, making it easier for individuals to manage their diabetes consistently.
  • Beyond blood sugar control, ISTAMET D XR 1000MG TABLET 7'S may offer additional benefits for individuals with type 2 diabetes. Metformin, in particular, has been associated with modest weight loss or weight stabilization in some patients, which can be beneficial for those who are overweight or obese. Improved blood sugar control can also reduce the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems. By effectively managing blood glucose levels, ISTAMET D XR 1000MG TABLET 7'S contributes to better overall health and well-being for individuals with type 2 diabetes, allowing them to lead more active and fulfilling lives. Regular use, as prescribed by a healthcare professional, alongside a healthy diet and exercise, maximizes its effectiveness.
  • ISTAMET D XR 1000MG Tablet 7's contributes to comprehensive diabetes management, targeting multiple pathways involved in blood sugar regulation. This multifaceted approach can lead to a more significant reduction in HbA1c levels compared to single-agent therapy. By optimizing blood glucose control, ISTAMET D XR 1000MG Tablet 7's helps to alleviate common diabetes symptoms like excessive thirst, frequent urination, and fatigue, enhancing the patient's quality of life. Moreover, it supports cardiovascular health by mitigating the risk factors associated with hyperglycemia and promoting healthier metabolic function. The convenience of a single tablet formulation improves patient compliance and simplifies the daily treatment regimen, making it easier for individuals to adhere to their prescribed medication schedule.
  • The combination of metformin and a DPP-4 inhibitor in ISTAMET D XR 1000MG Tablet 7's offers a synergistic effect, maximizing therapeutic outcomes while minimizing the risk of adverse effects. Metformin's action on hepatic glucose production complements the DPP-4 inhibitor's modulation of incretin hormones, providing a balanced approach to glycemic control. This combination therapy is particularly beneficial for patients who have not achieved adequate glycemic control with metformin alone. By addressing multiple facets of diabetes pathophysiology, ISTAMET D XR 1000MG Tablet 7's helps to prevent the progression of the disease and reduce the likelihood of long-term complications. It is an effective tool for managing blood sugar levels and improving overall health outcomes for individuals with type 2 diabetes.

How to use ISTAMET D XR 1000MG TABLET 7'SArrow

  • ISTAMET D XR 1000MG TABLET 7'S is designed to help manage blood sugar levels in adults with type 2 diabetes. It's crucial to take this medication exactly as your doctor prescribes. The usual recommendation is to take it once daily, with your evening meal to minimize potential stomach upset. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this can affect how the medication is released in your body. Consistency is key, so try to take it at the same time each day to maintain a steady level of medication in your bloodstream.
  • Before you start taking ISTAMET D XR 1000MG TABLET 7'S, inform your doctor about any other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. This will help prevent any potential drug interactions. Also, tell your doctor about any existing medical conditions, especially kidney or liver problems, as these can affect how your body processes the medication. Regular monitoring of your kidney function may be necessary while you are taking this medicine.
  • While taking ISTAMET D XR 1000MG TABLET 7'S, it's important to maintain a healthy lifestyle. This includes following a balanced diet, exercising regularly, and monitoring your blood sugar levels as directed by your doctor. If you experience any unusual side effects, such as persistent nausea, vomiting, abdominal pain, or unusual tiredness, contact your doctor immediately. These could be signs of a more serious problem. Do not stop taking the medication without consulting your doctor, even if you feel well, as this could lead to a rise in your blood sugar levels. Remember to keep all your scheduled appointments with your doctor and laboratory for regular check-ups and monitoring.

Quick Tips for ISTAMET D XR 1000MG TABLET 7'SArrow

  • Take ISTAMET D XR 1000MG TABLET 7'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a glass of water. Usually, it is taken once daily with the evening meal to minimize stomach upset.
  • ISTAMET D XR 1000MG TABLET 7'S helps control high blood sugar. Continue to follow your diet and exercise program as directed by your doctor. Regular physical activity and a balanced diet are crucial for managing your diabetes effectively alongside this medication.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider. Keep a record of your readings and share them with your doctor during your appointments. This will help them assess how well the medication is working and adjust your treatment plan if needed.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, rapid heartbeat, and confusion. Carry a source of fast-acting sugar with you, such as glucose tablets or fruit juice, to treat hypoglycemia promptly. Inform your family and friends about recognizing and managing hypoglycemia.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with ISTAMET D XR 1000MG TABLET 7'S. Pay special attention to medications that can affect blood sugar levels, such as corticosteroids or diuretics. Also, notify your doctor if you have any kidney or liver problems before starting this medication.

Food Interactions with ISTAMET D XR 1000MG TABLET 7'SArrow

  • ISTAMET D XR 1000MG TABLET 7'S should be taken with food to decrease the chance of an upset stomach.
  • Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.
  • Follow your doctor's dietary recommendations carefully while taking this medication to manage your blood sugar levels effectively.

FAQs

What is Istamet D XR 1000mg Tablet 7's and what is it used for?Arrow

Istamet D XR 1000mg Tablet 7's is a combination medicine used to control high blood sugar levels in adults with type 2 diabetes mellitus. It is used along with diet and exercise.

What are the active ingredients in Istamet D XR 1000mg Tablet 7's?Arrow

Istamet D XR 1000mg Tablet 7's contains two active ingredients: Sitagliptin and Metformin Hydrochloride.

How should I take Istamet D XR 1000mg Tablet 7's?Arrow

Take Istamet D XR 1000mg Tablet 7's exactly as prescribed by your doctor. Take it with food, and swallow the tablet whole; do not chew or crush it.

What are the common side effects of Istamet D XR 1000mg Tablet 7's?Arrow

Common side effects of Istamet D XR 1000mg Tablet 7's include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is Istamet D XR 1000mg Tablet 7's safe for people with kidney problems?Arrow

Istamet D XR 1000mg Tablet 7's is not recommended for people with kidney problems. Talk to your doctor if you have kidney issues.

Can Istamet D XR 1000mg Tablet 7's be taken on an empty stomach?Arrow

It is recommended to take Istamet D XR 1000mg Tablet 7's with food to avoid stomach upset.

What happens if I miss a dose of Istamet D XR 1000mg Tablet 7's?Arrow

If you miss a dose of Istamet D XR 1000mg Tablet 7's, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Can Istamet D XR 1000mg Tablet 7's interact with other medications?Arrow

Istamet D XR 1000mg Tablet 7's can interact with certain other medications, such as insulin, sulfonylureas, and some blood pressure medications. Tell your doctor about all your medications.

How should I store Istamet D XR 1000mg Tablet 7's?Arrow

Store Istamet D XR 1000mg Tablet 7's at room temperature, away from direct sunlight and moisture. Keep out of reach of children and pets.

Can I drink alcohol while taking Istamet D XR 1000mg Tablet 7's?Arrow

It is not recommended to drink alcohol while taking Istamet D XR 1000mg Tablet 7's, as it can increase the risk of low blood sugar levels and other side effects.

Is Istamet D XR 1000mg Tablet 7's safe during pregnancy?Arrow

The safety of Istamet D XR 1000mg Tablet 7's during pregnancy has not been established. Talk to your doctor if you are pregnant or planning to become pregnant.

Is Istamet D XR 1000mg Tablet 7's safe during breastfeeding?Arrow

It is not known whether Istamet D XR 1000mg Tablet 7's is excreted in breast milk. Talk to your doctor before using it during breastfeeding.

What are other medications that contain Metformin?Arrow

Other medications that contain Metformin include Glucophage, Glucophage XR, Fortamet, and Riomet.

What are other medications that contain Sitagliptin?Arrow

Other medications that contain Sitagliptin include Januvia.

What happens if I overdose on Istamet D XR 1000mg Tablet 7's?Arrow

If you overdose on Istamet D XR 1000mg Tablet 7's, seek immediate medical attention.

What is Istamet D XR 1000MG Tablet 7's used for?Arrow

Istamet D XR 1000MG Tablet 7's is used for type 2 diabetes mellitus; also used in heart failure and chronic kidney disease in selected patients; first-line management of type 2 diabetes mellitus, usually alongside diet and exercise; and management of type 2 diabetes mellitus alongside diet and exercise, alone or with other antidiabetic medicines. Istamet D XR 1000MG Tablet 7's contains Dapagliflozin 10 MG + Metformin Hydrochloride 1000 MG Sustained Release + Sitagliptin 100 MG. Always use Istamet D XR 1000MG Tablet 7's as advised by your doctor.

What is the composition of Istamet D XR 1000MG Tablet 7's?Arrow

Istamet D XR 1000MG Tablet 7's contains Dapagliflozin 10 MG + Metformin Hydrochloride 1000 MG Sustained Release + Sitagliptin 100 MG. It is a SGLT2 inhibitor; biguanide antidiabetic; and DPP-4 inhibitor antidiabetic.

What are the side effects of Istamet D XR 1000MG Tablet 7's?Arrow

Commonly reported side effects of Istamet D XR 1000MG Tablet 7's include genital fungal infections, urinary tract infections, increased urination, thirst, dehydration; diarrhoea, nausea, abdominal discomfort, metallic taste, loss of appetite — often improve with time or when taken with food; and headache, upper respiratory symptoms, nasal congestion, sore throat. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Istamet D XR 1000MG Tablet 7's?Arrow

Istamet D XR 1000MG Tablet 7's is listed at Rs. 142.8 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Istamet D XR 1000MG Tablet 7's?Arrow

Risk of euglycaemic diabetic ketoacidosis — ketones may be raised with near-normal glucose; seek care for nausea, vomiting or abdominal pain; Rare but serious risk of lactic acidosis, particularly with kidney impairment, dehydration, acute illness or excess alcohol; and Rare reports of acute pancreatitis — stop and seek care for severe persistent abdominal pain. Tell your doctor about all other medicines you take before starting Istamet D XR 1000MG Tablet 7's.

What is the correct dosage of Istamet D XR 1000MG Tablet 7's?Arrow

The dose of Istamet D XR 1000MG Tablet 7's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Istamet D XR 1000MG Tablet 7's?Arrow

A generic medicine is one with the same active composition as the branded product — for Istamet D XR 1000MG Tablet 7's that is Dapagliflozin 10 MG + Metformin Hydrochloride 1000 MG Sustained Release + Sitagliptin 100 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Istamet D XR 1000MG Tablet 7's.

How does Istamet D XR 1000MG Tablet 7's work?Arrow

Istamet D XR 1000MG Tablet 7's contains Dapagliflozin 10 MG + Metformin Hydrochloride 1000 MG Sustained Release + Sitagliptin 100 MG, a SGLT2 inhibitor; biguanide antidiabetic; and DPP-4 inhibitor antidiabetic. It is used for type 2 diabetes mellitus.

Is Istamet D XR 1000MG Tablet 7's a prescription medicine?Arrow

Yes. Istamet D XR 1000MG Tablet 7's requires a valid doctor's prescription.

Who is the manufacturer of Istamet D XR 1000MG Tablet 7's?Arrow

Istamet D XR 1000MG Tablet 7's is manufactured by Sun Pharmaceutical Industries Ltd.

What is the dosage form of Istamet D XR 1000MG Tablet 7's?Arrow

Istamet D XR 1000MG Tablet 7's is supplied as a tablet and is taken by the oral route.

What are the benefits of Istamet D XR 1000MG Tablet 7's?Arrow

Istamet D XR 1000MG Tablet 7's contains Dapagliflozin 10 MG + Metformin Hydrochloride 1000 MG Sustained Release + Sitagliptin 100 MG. It is used for type 2 diabetes mellitus; also used in heart failure and chronic kidney disease in selected patients; first-line management of type 2 diabetes mellitus, usually alongside diet and exercise; and management of type 2 diabetes mellitus alongside diet and exercise, alone or with other antidiabetic medicines. The benefit you get depends on the condition your doctor prescribed Istamet D XR 1000MG Tablet 7's for.

Is Istamet D XR 1000MG Tablet 7's safe to take daily?Arrow

Whether Istamet D XR 1000MG Tablet 7's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Istamet D XR 1000MG Tablet 7's on your own.

When should Istamet D XR 1000MG Tablet 7's be taken — morning or night?Arrow

The timing of Istamet D XR 1000MG Tablet 7's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Istamet D XR 1000MG Tablet 7's without a doctor's consultation?Arrow

No. Istamet D XR 1000MG Tablet 7's is a prescription medicine and should only be taken on a doctor's advice.

Can Istamet D XR 1000MG Tablet 7's be taken during pregnancy or breastfeeding?Arrow

Do not take Istamet D XR 1000MG Tablet 7's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

How should Istamet D XR 1000MG Tablet 7's be stored?Arrow

Store Istamet D XR 1000MG Tablet 7's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

Book Icon

Sitagliptin and Metformin Hydrochloride Tablets, Initial U.S. Approval: 2007. Highlights of Prescribing Information. See 16 for Patient Counseling Information. Revision date: 04/2012. This is the prescribing information from the FDA which may contain relevant information on Sitagliptin and Metformin.

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DrugBank: Sitagliptin. A comprehensive drug database entry for Sitagliptin, providing detailed information on its mechanism of action, pharmacology, and uses.

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Book Icon

DrugBank: Metformin. A comprehensive drug database entry for Metformin, providing detailed information on its mechanism of action, pharmacology, and uses.

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Book Icon

Defronzo, R. A., et al. (2014). Combination therapy with sitagliptin and metformin. International Journal of Clinical Practice, 68(5), 641–653. This article discusses the clinical use of sitagliptin and metformin in combination for treating type 2 diabetes.

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Book Icon

European Medicines Agency (EMA): Janumet. Janumet is a medicine containing two active substances, sitagliptin and metformin hydrochloride. It is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

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Book Icon

RxList: Janumet. Janumet (sitagliptin and metformin hydrochloride) is a combination of two oral diabetes medicines that help control blood sugar levels.

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