DAPAVEL M 10/500MG TABLET
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DAPAVEL M 10/500MG TABLET 10'S

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DAPAVEL M 10/500MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

165

₹140.25

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About DAPAVEL M 10/500MG TABLET 10'S

  • DAPAVEL M 10/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It combines two powerful medications, Dapagliflozin and Metformin, to effectively manage blood sugar levels. This medication is typically prescribed when diet and exercise alone are not sufficient to control hyperglycemia in adults with type 2 diabetes.
  • Dapagliflozin belongs to a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, thereby lowering blood sugar levels. This mechanism also provides additional benefits such as potential weight loss and blood pressure reduction.
  • Metformin, on the other hand, is a biguanide that primarily works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. It also helps to slow down the absorption of glucose from the intestines. Metformin is a well-established and widely used medication for type 2 diabetes, known for its efficacy and safety profile.
  • The combination of Dapagliflozin and Metformin in DAPAVEL M 10/500MG provides a synergistic effect, addressing multiple pathways involved in blood sugar regulation. This helps to achieve better glycemic control compared to using either medication alone. The 10/500mg strength indicates that each tablet contains 10mg of Dapagliflozin and 500mg of Metformin.
  • DAPAVEL M 10/500MG TABLET is usually taken once or twice daily with meals, as directed by your healthcare provider. It's crucial to follow the prescribed dosage and timing to maximize its effectiveness and minimize potential side effects. Common side effects may include nausea, diarrhea, and increased urination. It's important to stay hydrated while taking this medication.
  • This medication is a prescription drug and should only be used under the guidance of a qualified healthcare professional. Regular monitoring of blood sugar levels and kidney function is recommended during treatment. Always inform your doctor about any other medications you are taking to avoid potential drug interactions. DAPAVEL M 10/500MG TABLET, along with a healthy lifestyle, can significantly improve blood sugar control and overall health in individuals with type 2 diabetes.

Uses of DAPAVEL M 10/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering blood sugar levels
  • Management of high blood sugar
  • Improving insulin sensitivity
  • Preventing diabetic complications
  • Managing insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)
  • Reducing cardiovascular risk (in some patients)

How DAPAVEL M 10/500MG TABLET 10'S Works

  • DAPAVEL M 10/500MG TABLET is a combination medication containing Dapagliflozin and Metformin, designed to manage type 2 diabetes mellitus effectively. These two active ingredients work through complementary mechanisms to lower blood glucose levels and improve overall glycemic control.
  • Dapagliflozin belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys that reabsorbs glucose back into the bloodstream. Dapagliflozin inhibits SGLT2, reducing the reabsorption of glucose. As a result, excess glucose is excreted through the urine, lowering blood sugar levels. This mechanism is insulin-independent, meaning it works even if the body's insulin isn't functioning properly.
  • Metformin, on the other hand, is a biguanide that primarily works by decreasing glucose production in the liver. It reduces hepatic glucose output by suppressing gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Metformin also improves insulin sensitivity in peripheral tissues like muscles, allowing cells to utilize glucose more efficiently. Furthermore, Metformin slows down the absorption of glucose from the intestines, further contributing to lower post-meal blood sugar spikes.
  • The combination of Dapagliflozin and Metformin in DAPAVEL M offers a dual approach to managing blood sugar. Dapagliflozin helps remove excess glucose from the body via the kidneys, while Metformin reduces glucose production in the liver and enhances insulin sensitivity. This synergistic action helps to achieve better blood sugar control compared to using either medication alone.
  • By lowering blood glucose levels, DAPAVEL M helps to reduce the risk of long-term complications associated with diabetes, such as heart disease, kidney damage, nerve damage, and vision problems. It is typically used in conjunction with diet and exercise to achieve optimal blood sugar control. Regular monitoring of blood sugar levels and adherence to a healthy lifestyle are crucial for the successful management of type 2 diabetes.

Side Effects of DAPAVEL M 10/500MG TABLET 10'SArrow

Possible side effects of DAPAVEL M 10/500MG TABLET may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, fatigue, skin rash, itching. * **Uncommon:** Allergic reactions (hives, swelling), constipation, indigestion, increased thirst, frequent urination, blurred vision, changes in liver function tests, vitamin B12 deficiency, lactic acidosis (rare but serious).

Safety Advice for DAPAVEL M 10/500MG TABLET 10'SArrow

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Allergies

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Do not use this medicine if you are allergic to it, as it may cause an allergic reaction.

Dosage of DAPAVEL M 10/500MG TABLET 10'SArrow

  • The recommended dosage of DAPAVEL M 10/500MG TABLET 10'S is individualized and depends on several factors, including your blood glucose levels, overall health, and other medications you may be taking. It is crucial to strictly adhere to the dosage prescribed by your healthcare provider. Typically, the starting dose is one tablet taken orally once or twice daily, usually with meals, to minimize gastrointestinal side effects. Your doctor may gradually adjust the dosage based on your glycemic response and tolerance, up to a maximum daily dose.
  • It is important to take DAPAVEL M 10/500MG TABLET 10'S at the same time(s) each day to maintain consistent blood glucose control. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Regular monitoring of your blood glucose levels is essential while taking DAPAVEL M 10/500MG TABLET 10'S to assess the effectiveness of the medication and make any necessary dosage adjustments. Your doctor may also recommend periodic kidney function tests, as metformin, one of the active ingredients in DAPAVEL M 10/500MG TABLET 10'S, can affect kidney function in some individuals. Always inform your doctor about all the medications, supplements, and herbal products you are taking, as they may interact with DAPAVEL M 10/500MG TABLET 10'S.
  • Take 'DAPAVEL M 10/500MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DAPAVEL M 10/500MG TABLET 10'S?Arrow

  • If you miss a dose of DAPAVEL M 10/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store DAPAVEL M 10/500MG TABLET 10'S?Arrow

  • Keep DAPAVEL M 10/500MG TAB 1X10 away from the reach of children and pets.
  • Store DAPAVEL M 10/500MG TAB 1X10 at room temperature.

Benefits of DAPAVEL M 10/500MG TABLET 10'SArrow

  • DAPAVEL M 10/500MG TABLET 10'S is a combination medicine designed to effectively manage blood sugar levels in individuals with type 2 diabetes. It combines two powerful active ingredients: dapagliflozin and metformin. This dual-action approach provides a comprehensive strategy to control hyperglycemia and improve overall glycemic control.
  • Dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, works by preventing the kidneys from reabsorbing glucose back into the bloodstream. Instead, the excess glucose is excreted through urine, leading to a reduction in blood sugar levels. This mechanism is particularly beneficial as it does not rely on insulin secretion, reducing the risk of hypoglycemia (low blood sugar).
  • Metformin, a biguanide, primarily reduces glucose production in the liver and improves the body's sensitivity to insulin. It helps insulin work more effectively, allowing cells to absorb glucose from the bloodstream more efficiently. Metformin also slows down the absorption of glucose from the intestines, further contributing to blood sugar control.
  • The synergistic action of dapagliflozin and metformin offers several key benefits for individuals with type 2 diabetes. Firstly, it provides robust glycemic control by targeting multiple pathways involved in blood sugar regulation. This can lead to a significant reduction in HbA1c levels, a measure of long-term blood sugar control.
  • Secondly, DAPAVEL M 10/500MG TABLET 10'S may promote weight loss in some individuals. Dapagliflozin's mechanism of action leads to the excretion of excess glucose in urine, resulting in a loss of calories. Metformin can also contribute to weight management through its effects on insulin sensitivity and glucose metabolism.
  • Thirdly, this medication may offer cardiovascular benefits. Studies have shown that SGLT2 inhibitors like dapagliflozin can reduce the risk of heart failure and cardiovascular death in individuals with type 2 diabetes who also have established cardiovascular disease or multiple cardiovascular risk factors.
  • Fourthly, DAPAVEL M 10/500MG TABLET 10'S can help improve blood pressure control. Dapagliflozin can lead to a mild reduction in blood pressure, which is beneficial for individuals with diabetes who often have co-existing hypertension.
  • Fifthly, the combination of dapagliflozin and metformin can reduce the risk of certain diabetes-related complications, such as kidney disease. SGLT2 inhibitors have demonstrated kidney-protective effects in clinical trials.
  • Finally, DAPAVEL M 10/500MG TABLET 10'S is a convenient once-daily oral medication, making it easier for individuals to adhere to their treatment plan. This can improve overall treatment outcomes and quality of life.
  • By effectively managing blood sugar levels, promoting weight loss, offering potential cardiovascular and kidney benefits, and simplifying treatment adherence, DAPAVEL M 10/500MG TABLET 10'S plays a crucial role in the comprehensive management of type 2 diabetes.

How to use DAPAVEL M 10/500MG TABLET 10'SArrow

  • DAPAVEL M 10/500MG TABLET 10'S is a prescription medication used to manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients: dapagliflozin and metformin. Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors, which work by helping the kidneys remove glucose from the bloodstream through urine. Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves insulin sensitivity.
  • To get the most benefit from DAPAVEL M, take it exactly as your doctor prescribes. The usual starting dose is one tablet once or twice daily, taken with meals to reduce the risk of stomach upset. Your doctor may adjust your dosage based on your blood sugar levels and how well you tolerate the medication. Do not crush, chew, or break the tablet; swallow it whole with a glass of water.
  • It is crucial to take DAPAVEL M at the same time(s) each day to maintain consistent blood sugar control. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double your dose to make up for a missed one.
  • While taking DAPAVEL M, it's essential to follow a healthy diet and exercise regularly. This medication works best when combined with lifestyle changes. Monitor your blood sugar levels regularly as directed by your doctor and report any unusual symptoms or side effects, such as urinary tract infections, yeast infections, or symptoms of low blood sugar (hypoglycemia).
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting DAPAVEL M, as some may interact with it. Also, it's important to stay hydrated by drinking plenty of fluids while taking this medication. Regular check-ups with your doctor are necessary to monitor your kidney function and overall health while on DAPAVEL M 10/500MG TABLET 10'S.

Quick Tips for DAPAVEL M 10/500MG TABLET 10'SArrow

  • Take DAPAVEL M 10/500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting them. It's usually taken once or twice daily with meals to minimize stomach upset and maintain consistent blood sugar levels. Consistent timing is key for optimal results.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider while taking DAPAVEL M 10/500MG TABLET 10'S. Keep a record of your readings and share it with your doctor during check-ups. This helps them adjust your dosage as needed and track your progress effectively.
  • Follow a healthy diet and exercise regularly while taking DAPAVEL M 10/500MG TABLET 10'S. This medication works best when combined with lifestyle changes. Focus on a balanced diet rich in fiber, lean protein, and whole grains, and aim for at least 30 minutes of moderate-intensity exercise most days of the week. Always consult your doctor before starting any new diet or exercise program.
  • Be aware of the symptoms of low blood sugar (hypoglycemia) such as sweating, shaking, dizziness, rapid heartbeat, and confusion. Keep a source of fast-acting sugar like glucose tablets or fruit juice with you at all times in case you experience these symptoms. Knowing how to recognize and treat hypoglycemia is crucial when taking DAPAVEL M 10/500MG TABLET 10'S.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting DAPAVEL M 10/500MG TABLET 10'S. Certain medications can interact with this medicine and affect its effectiveness or increase the risk of side effects. This includes over-the-counter drugs as well.

Food Interactions with DAPAVEL M 10/500MG TABLET 10'SArrow

  • DAPAVEL M 10/500MG TABLET 10'S is generally safe to take with or without food. However, it's best to take it at the same time each day to maintain consistent blood sugar levels. If you experience stomach upset, taking it with food might help. Avoid excessive alcohol consumption as it can increase the risk of side effects like hypoglycemia (low blood sugar) and lactic acidosis.
  • Always follow your doctor's specific instructions regarding diet and medication timing.

FAQs

What is DAPAVEL M 10/500mg Tablet used for?Arrow

DAPAVEL M 10/500mg Tablet is used to treat type 2 diabetes mellitus by lowering blood sugar levels.

How should I take DAPAVEL M 10/500mg Tablet?Arrow

Take DAPAVEL M 10/500mg Tablet as prescribed by your doctor. Swallow it whole with a glass of water. Do not crush or chew it. It is usually taken once or twice daily with meals.

What are the common side effects of DAPAVEL M 10/500mg Tablet?Arrow

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Consult your doctor if these persist or worsen.

Can I take DAPAVEL M 10/500mg Tablet if I have kidney problems?Arrow

Inform your doctor if you have kidney problems before taking DAPAVEL M 10/500mg Tablet, as it may affect kidney function. Dose adjustments or alternative medications might be necessary.

Can I drive after taking DAPAVEL M 10/500mg Tablet?Arrow

DAPAVEL M 10/500mg Tablet can cause dizziness or blurred vision in some individuals. Avoid driving or operating machinery if you experience these side effects.

What should I do if I miss a dose of DAPAVEL M 10/500mg Tablet?Arrow

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can DAPAVEL M 10/500mg Tablet be used in children?Arrow

DAPAVEL M 10/500mg Tablet is generally not recommended for use in children. Consult your doctor for appropriate treatment options.

What should I avoid while taking DAPAVEL M 10/500mg Tablet?Arrow

Avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of side effects. Also, maintain a healthy diet and exercise regularly.

How should DAPAVEL M 10/500mg Tablet be stored?Arrow

Store DAPAVEL M 10/500mg Tablet at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

Can DAPAVEL M 10/500mg Tablet cause hypoglycemia?Arrow

Yes, DAPAVEL M 10/500mg Tablet can cause hypoglycemia (low blood sugar), especially when taken with other diabetes medications or insulin. Be aware of the symptoms of hypoglycemia and take necessary precautions.

What are the symptoms of hypoglycemia and what should I do?Arrow

Symptoms of hypoglycemia include sweating, trembling, rapid heartbeat, dizziness, hunger, blurred vision, and confusion. If you experience these, consume a sugary snack or drink (e.g., glucose tablets, juice) and seek medical attention if symptoms persist.

Can I take DAPAVEL M 10/500mg Tablet during pregnancy or breastfeeding?Arrow

DAPAVEL M 10/500mg Tablet is generally not recommended during pregnancy or breastfeeding. Consult your doctor to discuss alternative treatments.

Are there any drug interactions with DAPAVEL M 10/500mg Tablet?Arrow

DAPAVEL M 10/500mg Tablet may interact with certain medications, including diuretics, corticosteroids, and thyroid hormones. Inform your doctor about all the medications you are taking to avoid potential interactions.

Is Dapavel M 10/500mg tablet same as Vildagliptin and Metformin combination?Arrow

No, Dapavel M 10/500mg tablet contains Dapagliflozin and Metformin as a combination. Vildagliptin and Metformin are different.

References

Book Icon

DrugBank: Dapagliflozin. Provides comprehensive information on dapagliflozin, including its mechanism of action, pharmacokinetics, and interactions.

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FDA Prescribing Information for FARXIGA (dapagliflozin). Contains detailed information on clinical trials, indications, dosage, and safety.

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European Medicines Agency (EMA) - Forxiga (dapagliflozin). Provides the European regulatory perspective on dapagliflozin, including assessment reports and product information.

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PMC - Dapagliflozin: a review of its use in the treatment of type 2 diabetes mellitus. A review article discussing the clinical use and efficacy of dapagliflozin.

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DrugBank: Metformin. Provides detailed information on metformin's pharmacology, uses, and interactions.

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FDA Prescribing Information for Metformin Hydrochloride. Contains comprehensive prescribing information, including clinical studies and safety data.

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European Medicines Agency (EMA) - Glucophage (metformin). Provides the European regulatory view on metformin, including its assessment reports.

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PMC - Metformin: An Update. A review article discussing various aspects of metformin, including its mechanism of action and clinical applications.

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