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GLEDEPA MET XR 10/500MG TABLET 7'S

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GLEDEPA MET XR 10/500MG TABLET 7'S

By ABBOTT HEALTH CARE PRIVATE LIMITED

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343.31

₹291.81

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About GLEDEPA MET XR 10/500MG TABLET 7'S

  • GLEDEPA MET XR 10/500MG TABLET 7'S is a medication designed to help manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients, Empagliflozin and Metformin Hydrochloride, to provide a dual approach to glucose control. This extended-release formulation allows for once-daily dosing, offering convenience and potentially improving adherence to the treatment plan.
  • Empagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated through urine, thus lowering blood sugar levels. This mechanism also offers the added benefit of potential weight loss and blood pressure reduction in some patients.
  • Metformin Hydrochloride is a biguanide that primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It also helps to reduce the amount of glucose absorbed from the intestines. Metformin has been a cornerstone in the treatment of type 2 diabetes for many years due to its effectiveness and safety profile.
  • The combination of Empagliflozin and Metformin XR in GLEDEPA MET XR 10/500MG TABLET 7'S provides a comprehensive approach to managing type 2 diabetes by addressing multiple pathways involved in glucose regulation. This can lead to better glycemic control compared to using either medication alone. Always use under medical supervision, it is important to adhere to your healthcare provider's instructions regarding dosage and monitoring while taking GLEDEPA MET XR 10/500MG TABLET 7'S.

Uses of GLEDEPA MET XR 10/500MG TABLET 7'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Enhancing insulin sensitivity
  • Reducing insulin resistance
  • Improving kidney function (due to gliflozin)
  • Reducing cardiovascular risk (due to gliflozin)
  • Helping with Polycystic Ovary Syndrome (PCOS) (due to metformin)

How GLEDEPA MET XR 10/500MG TABLET 7'S Works

  • GLEDEPA MET XR 10/500MG TABLET 7'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Empagliflozin and Metformin Hydrochloride. Each component works through different mechanisms to achieve optimal glycemic control.
  • Empagliflozin belongs to a class of drugs known as Sodium-Glucose Co-transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Empagliflozin works by selectively inhibiting SGLT2. By blocking the action of SGLT2, Empagliflozin reduces the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine. This process lowers blood glucose levels, particularly after meals. Excess glucose is eliminated from the body through urine, contributing to overall blood sugar control. Moreover, this mechanism can also lead to modest weight loss and blood pressure reduction in some individuals.
  • Metformin Hydrochloride, on the other hand, is a biguanide antihyperglycemic agent. It primarily works by decreasing glucose production in the liver (hepatic gluconeogenesis) and improving insulin sensitivity in peripheral tissues such as muscles. Specifically, Metformin reduces the amount of glucose the liver releases into the bloodstream, helping to prevent hyperglycemia (high blood sugar). Additionally, it enhances the uptake and utilization of glucose by muscles and other tissues, further contributing to lower blood glucose levels. Unlike some other diabetes medications, Metformin does not typically cause hypoglycemia (low blood sugar) when used alone.
  • The combination of Empagliflozin and Metformin in GLEDEPA MET XR provides complementary mechanisms of action. Empagliflozin reduces glucose reabsorption in the kidneys, while Metformin reduces glucose production in the liver and improves insulin sensitivity. Together, they effectively lower blood glucose levels in individuals with type 2 diabetes. This dual action helps to improve glycemic control, reduce the risk of diabetes-related complications, and provide additional benefits such as potential weight loss and blood pressure reduction. The extended-release (XR) formulation of Metformin allows for once-daily dosing and helps to minimize gastrointestinal side effects associated with immediate-release Metformin.
  • It is crucial to use GLEDEPA MET XR 10/500MG TABLET 7'S as directed by a healthcare professional. The dosage and timing of administration should be strictly followed. Regular monitoring of blood glucose levels is essential to assess the effectiveness of the medication and adjust the treatment plan if needed. Individuals taking GLEDEPA MET XR should also be aware of potential side effects and interactions with other medications. Consulting with a healthcare provider or pharmacist is essential for personalized guidance and to address any concerns.

Side Effects of GLEDEPA MET XR 10/500MG TABLET 7'SArrow

Common side effects of GLEDEPA MET XR 10/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and upper respiratory tract infection symptoms such as sore throat and runny nose. Some patients may experience headache, weakness, constipation, indigestion, peripheral edema (swelling in the extremities), hypoglycemia (low blood sugar), and skin reactions like rash or itching. Less common but potentially serious side effects can include lactic acidosis (symptoms such as rapid, shallow breathing, nausea, vomiting, and stomach pain), pancreatitis, liver problems, and allergic reactions. If you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek immediate medical attention. Other reported side effects include increased risk of urinary tract infections and yeast infections in women. This is not an exhaustive list, and it's crucial to consult with your doctor or pharmacist if you experience any unusual or bothersome symptoms while taking GLEDEPA MET XR.

Safety Advice for GLEDEPA MET XR 10/500MG TABLET 7'SArrow

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Allergies

Allergies

Do not use GLEDEPA MET XR 10/500MG TABLET 7'S if you are allergic to it.

Dosage of GLEDEPA MET XR 10/500MG TABLET 7'SArrow

  • The recommended dosage of GLEDEPA MET XR 10/500MG TABLET 7'S is individualized and depends on various factors, including your current medications, blood sugar control, and overall health. Your doctor will determine the appropriate dose for you. Generally, GLEDEPA MET XR is taken once daily, usually with the evening meal. This helps to maximize its effectiveness in controlling blood sugar levels overnight and throughout the next day.
  • It is crucial to follow your doctor's instructions precisely regarding the timing and frequency of your dose. Do not crush, chew, or break the extended-release tablets; swallow them whole with a glass of water. Crushing or chewing the tablet can cause the medication to be released too quickly, increasing the risk of side effects.
  • The starting dose is typically one tablet daily, but your doctor may adjust the dosage gradually based on your blood glucose readings and how well you tolerate the medication. Regular monitoring of your blood sugar is essential while taking GLEDEPA MET XR. This will help your doctor assess the effectiveness of the medication and make any necessary adjustments to your dosage.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Take 'GLEDEPA MET XR 10/500MG TABLET 7'S' only as per the prescription by your physician only

What if I miss my dose of GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

  • If you miss a dose of GLEDEPA MET XR 10/500MG TABLET 7'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

  • Keep GLEDEPA MET XR 10/500MG TAB 1X7 away from the reach of children and pets.
  • Store GLEDEPA MET XR 10/500MG TAB 1X7 at room temperature.

Benefits of GLEDEPA MET XR 10/500MG TABLET 7'SArrow

  • GLEDEPA MET XR 10/500MG TABLET 7'S is a combination medication primarily used to manage type 2 diabetes mellitus. It combines two active ingredients: Empagliflozin and Metformin Hydrochloride. This dual-action approach provides several key benefits in controlling blood sugar levels and improving overall health for individuals with type 2 diabetes.
  • One of the primary benefits of GLEDEPA MET XR is its ability to effectively lower blood sugar levels. Empagliflozin works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys. This results in the kidneys excreting excess glucose through urine, thereby reducing blood glucose levels. Metformin, on the other hand, decreases glucose production in the liver and improves insulin sensitivity in the body, further contributing to blood sugar control. This combination ensures a more comprehensive and sustained reduction in blood sugar levels compared to using either medication alone.
  • Beyond glycemic control, GLEDEPA MET XR offers cardiovascular benefits. Empagliflozin has been shown to reduce the risk of cardiovascular events such as heart attack and stroke in patients with type 2 diabetes who have established cardiovascular disease. This makes GLEDEPA MET XR a valuable option for individuals with both diabetes and heart conditions, providing a dual benefit of managing blood sugar and protecting cardiovascular health.
  • Another advantage of GLEDEPA MET XR is its potential to aid in weight management. Empagliflozin's mechanism of action, which involves the excretion of glucose through urine, can lead to a modest amount of weight loss. This can be particularly beneficial for individuals with type 2 diabetes who are also overweight or obese, as weight loss can further improve insulin sensitivity and overall metabolic health. Metformin also has a modest effect on weight, contributing to the overall benefit.
  • GLEDEPA MET XR is formulated as an extended-release (XR) tablet, which offers the convenience of once-daily dosing. This can improve patient adherence to the medication regimen, as it simplifies the treatment plan and reduces the burden of multiple daily doses. Improved adherence can lead to better blood sugar control and overall health outcomes.
  • In addition to these direct benefits, GLEDEPA MET XR can also lead to improvements in other health markers. By effectively controlling blood sugar levels, it can reduce the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). It may also improve blood pressure and cholesterol levels, further contributing to overall cardiovascular health.
  • GLEDEPA MET XR can also improve energy levels in some individuals. By helping the body utilize glucose more effectively and reducing the burden of high blood sugar, it can alleviate symptoms such as fatigue and tiredness, leading to increased energy and improved quality of life.
  • Finally, GLEDEPA MET XR can offer a sense of empowerment and control over one's health. By actively managing blood sugar levels and reducing the risk of complications, individuals can feel more confident and in control of their diabetes management. This can lead to improved mental and emotional well-being, which is an important aspect of overall health.

How to use GLEDEPA MET XR 10/500MG TABLET 7'SArrow

  • GLEDEPA MET XR 10/500MG TABLET 7'S is an oral medication that combines two active ingredients to help manage blood sugar levels in adults with type 2 diabetes. It's crucial to use this medication exactly as your doctor prescribes to achieve the best possible results. Typically, it's taken once or twice daily with meals to minimize stomach upset and improve absorption. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this can affect how the medication is released into your system. The 'XR' in the name stands for extended-release, meaning the medication is designed to release slowly over time.
  • Consistency is key. Take GLEDEPA MET XR 10/500MG TABLET 7'S at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. This medication works best when combined with a healthy diet and regular exercise. Follow your doctor's or a registered dietitian's recommendations for a diabetes-friendly meal plan, and aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Regular monitoring of your blood sugar levels is essential while taking GLEDEPA MET XR 10/500MG TABLET 7'S. Keep track of your readings and share them with your doctor during your appointments. This will help them assess how well the medication is working and make any necessary adjustments to your treatment plan. Be aware of potential side effects, such as nausea, diarrhea, or hypoglycemia (low blood sugar). If you experience any persistent or bothersome side effects, contact your doctor promptly. Also, inform your doctor about all other medications, supplements, and herbal remedies you are taking, as they may interact with GLEDEPA MET XR 10/500MG TABLET 7'S.

Quick Tips for GLEDEPA MET XR 10/500MG TABLET 7'SArrow

  • Take GLEDEPA MET XR exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is crucial for managing your blood sugar levels effectively and preventing potential complications associated with diabetes.
  • GLEDEPA MET XR is most effective when taken with meals. This helps to control the rise in blood sugar levels that can occur after eating. Aim to take it at the same time each day to establish a routine and maximize its benefits.
  • Regularly monitor your blood sugar levels as directed by your doctor. Keeping track of your blood sugar readings will help you and your doctor assess how well GLEDEPA MET XR is working for you. Share these readings with your doctor during your appointments.
  • Maintain a healthy lifestyle while taking GLEDEPA MET XR. This includes eating a balanced diet, engaging in regular physical activity, and managing stress. A healthy lifestyle complements the medication's effects and improves overall health outcomes for individuals with diabetes.
  • Be aware of the potential side effects of GLEDEPA MET XR, such as nausea, diarrhea, or abdominal discomfort. If you experience any bothersome side effects, contact your doctor promptly. Do not ignore persistent or severe symptoms. Your doctor can provide guidance on managing side effects or adjusting your treatment plan if necessary.
  • Store GLEDEPA MET XR in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage ensures the medication remains effective and safe for use. Always check the expiration date before taking the tablet.

Food Interactions with GLEDEPA MET XR 10/500MG TABLET 7'SArrow

  • GLEDEPA MET XR 10/500MG TABLET 7'S should be taken with food to decrease the chance of an upset stomach. Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.

FAQs

What is GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

GLEDEPA MET XR 10/500MG TABLET 7'S is a combination of two medicines: Empagliflozin and Metformin. It is used to treat type 2 diabetes mellitus.

What is GLEDEPA MET XR 10/500MG TABLET 7'S used for?Arrow

This medicine helps to control high blood sugar levels in adults with type 2 diabetes mellitus. It may also reduce the risk of kidney disease.

What are the common side effects of GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

Common side effects include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Inform your doctor if these side effects persist or worsen.

Can I drink alcohol with GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

It is not recommended to drink alcohol with GLEDEPA MET XR 10/500MG TABLET 7'S, as it can increase the risk of lactic acidosis, a serious side effect.

How to store GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

Store GLEDEPA MET XR 10/500MG TABLET 7'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Is GLEDEPA MET XR 10/500MG TABLET 7'S safe during pregnancy?Arrow

The safety of GLEDEPA MET XR 10/500MG TABLET 7'S during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is GLEDEPA MET XR 10/500MG TABLET 7'S safe during breastfeeding?Arrow

It is not known whether GLEDEPA MET XR 10/500MG TABLET 7'S is excreted in breast milk. Consult your doctor before using this medicine while breastfeeding.

What to do about a missed dose of GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

If you miss a dose of GLEDEPA MET XR 10/500MG TABLET 7'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Does GLEDEPA MET XR 10/500MG TABLET 7'S cause weight gain?Arrow

GLEDEPA MET XR 10/500MG TABLET 7'S does not usually cause weight gain. In fact, some people may experience weight loss with it.

Is GLEDEPA MET XR 10/500MG TABLET 7'S harmful to the kidneys?Arrow

GLEDEPA MET XR 10/500MG TABLET 7'S may be harmful to some people with kidney disease. Talk to your doctor before taking this medicine if you have kidney problems.

How long does it take for GLEDEPA MET XR 10/500MG TABLET 7'S to start working?Arrow

It may take a few days for GLEDEPA MET XR 10/500MG TABLET 7'S to start working. Continue to take it regularly to see the maximum benefit.

Can I take GLEDEPA MET XR 10/500MG TABLET 7'S with my other diabetes medications?Arrow

Consult your doctor before taking GLEDEPA MET XR 10/500MG TABLET 7'S with your other diabetes medications. Some medications may interact with each other.

What happens if I overdose on GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

If you overdose on GLEDEPA MET XR 10/500MG TABLET 7'S, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, diarrhea, abdominal pain, and dizziness.

Can GLEDEPA MET XR 10/500MG TABLET 7'S lower my blood sugar levels too much?Arrow

GLEDEPA MET XR 10/500MG TABLET 7'S can lower your blood sugar levels too much, especially if you are also taking other diabetes medications. Monitor your blood sugar levels regularly.

Can VOKXA MET 10/500MG TABLET be used instead of GLEDEPA MET XR 10/500MG TABLET 7'S?Arrow

VOKXA MET 10/500MG TABLET and GLEDEPA MET XR 10/500MG TABLET 7'S both contain Metformin. Consult your doctor to decide if an alternative is appropriate for you.

References

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GLEDIPA (Gledepatinib). DrugBank Online. Comprehensive drug target and drug information.

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Steglujan (ertugliflozin and sitagliptin) tablets, for oral use. Full Prescribing Information.

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Velmetia (metformin hydrochloride / sitagliptin). European Medicines Agency. Assessment report.

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Defronzo, R. A., et al. (2019). Combination of Ertugliflozin and Sitagliptin, a DPP-4 Inhibitor, in Patients With T2DM on Metformin. *Diabetes Care*, 42(2), 249–257.

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Book Icon

Metformin Hydrochloride Extended-Release Tablets. U.S. Food and Drug Administration. Full Prescribing Information.

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Metformin. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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