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OXRAMET XR 10/500MG TABLET 7'S

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OXRAMET XR 10/500MG TABLET 7'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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128

₹108.8

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Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About OXRAMET XR 10/500MG TABLET 7'S

  • Oxramet XR 10/500 mg Tablet is a combination medicine used to treat type 2 diabetes mellitus. It helps control blood sugar and improve the body's response to insulin, and is prescribed when diet and exercise alone are not enough to manage blood sugar. It combines two active ingredients — dapagliflozin 10 mg and metformin hydrochloride 500 mg (sustained release) — that lower glucose through different, complementary routes.
  • Metformin is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity, so the body uses its own insulin more effectively. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, which works in the kidneys to remove excess glucose from the body through the urine, lowering blood sugar independently of insulin and often supporting modest weight and blood-pressure reduction. The sustained-release (XR) metformin releases gradually, which can be gentler on the stomach and suits once-daily dosing.
  • Oxramet XR is typically taken once daily, preferably with a meal, to reduce the risk of stomach upset, and the dose is decided by your doctor based on your condition and response to treatment. It is important to take it regularly at the same time each day for the most benefit, and to continue a healthy diet and regular exercise alongside it.
  • While taking Oxramet XR, monitor your blood sugar as directed and tell your doctor about any unusual symptoms or side effects. Common side effects may include nausea, diarrhoea, and abdominal pain; because of the SGLT2 component, genital and urinary tract infections can occur, and staying well hydrated is important. A rare but serious condition called diabetic ketoacidosis is possible, so seek prompt medical care for symptoms such as severe stomach pain, vomiting, difficulty breathing, or unusual drowsiness.
  • Oxramet XR should be used with caution in people with kidney or liver problems, and your doctor may check kidney function before and during treatment. It is a prescription medicine, so consult your doctor before starting or stopping it; they can give personalised guidance on its use and possible interactions with other medicines you take, including a temporary pause during acute illness, dehydration, or before certain procedures.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Oxramet XR 10/500mg Tablet 7's that is Metformin Hydrochloride 500 MG Sustained Release+dapagliflozin 10 MG. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of OXRAMET XR 10/500MG TABLET 7'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Inducing ovulation in polycystic ovary syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (potential)
  • Aiding in weight management (in some patients)

How OXRAMET XR 10/500MG TABLET 7'S Works

  • OXRAMET XR 10/500MG TABLET 7'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Dapagliflozin and Metformin Hydrochloride. Each component works through different mechanisms to achieve better glycemic control.
  • Dapagliflozin belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. The kidneys filter glucose from the blood, and SGLT2 proteins are responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin inhibits SGLT2 in the kidneys, reducing the reabsorption of glucose. This allows excess glucose to be excreted through urine, thereby lowering blood sugar levels. By removing glucose through the urinary tract, dapagliflozin also provides a slight caloric loss, which may contribute to weight management.
  • Metformin Hydrochloride is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. In people with type 2 diabetes, the liver sometimes produces excessive amounts of glucose. Metformin reduces hepatic glucose production, preventing blood sugar levels from rising too high. Additionally, metformin enhances insulin sensitivity, allowing cells to use insulin more effectively to take up glucose from the bloodstream. It also slightly slows down the absorption of glucose from the intestines after meals.
  • When combined, dapagliflozin and metformin offer complementary effects. Dapagliflozin promotes glucose excretion through the kidneys, while metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action helps to lower both fasting and post-meal blood sugar levels more effectively than either medicine alone. Regular use, in conjunction with diet and exercise, can significantly improve glycemic control in patients with type 2 diabetes. It is crucial to take OXRAMET XR 10/500MG TABLET 7'S as prescribed by your doctor, and to monitor blood sugar levels regularly to ensure optimal therapeutic outcomes.

Side Effects of OXRAMET XR 10/500MG TABLET 7'SArrow

OXRAMET XR 10/500MG TABLET 7'S can cause several side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and a metallic taste in the mouth. Some people may experience hypoglycemia (low blood sugar), especially when combined with other diabetes medications. Less common but more serious side effects include lactic acidosis (a buildup of lactic acid in the blood), which requires immediate medical attention. Symptoms of lactic acidosis include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness, or lightheadedness, and a slow or irregular heartbeat. Allergic reactions such as skin rash, itching, or hives are also possible. Other potential side effects include headache, dizziness, constipation, and upper respiratory tract infection. Report any persistent or severe side effects to your doctor.

Safety Advice for OXRAMET XR 10/500MG TABLET 7'SArrow

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Allergies

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Do not use OXRAMET XR 10/500MG TABLET 7'S if you are allergic to it.

Dosage of OXRAMET XR 10/500MG TABLET 7'SArrow

  • The recommended dosage of 'OXRAMET XR 10/500MG TABLET 7'S' varies depending on individual patient needs, as determined by your physician. It's crucial to adhere strictly to their instructions. The usual starting dose is typically one tablet once or twice daily, taken with meals to minimize gastrointestinal upset. Your doctor may gradually increase the dosage based on your blood glucose levels and overall response to the medication. The maximum daily dose should not exceed the amount prescribed by your healthcare provider.
  • The 'XR' in 'OXRAMET XR 10/500MG TABLET 7'S' stands for extended release, meaning the medication is released slowly into your system over a longer period. This allows for less frequent dosing compared to immediate-release formulations. Do not crush, chew, or break the tablets; swallow them whole with a glass of water. Doing so could disrupt the extended-release mechanism and lead to a rapid release of the medication, potentially causing adverse effects.
  • It is important to take 'OXRAMET XR 10/500MG TABLET 7'S' at the same time(s) each day to maintain consistent blood levels of the medication. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Regular monitoring of blood glucose levels is essential while taking 'OXRAMET XR 10/500MG TABLET 7'S' to assess the effectiveness of the medication and adjust the dosage accordingly. Discuss any concerns or questions you have about your dosage with your doctor or pharmacist.
  • Take 'OXRAMET XR 10/500MG TABLET 7'S' only as per the prescription by your physician only

What if I miss my dose of OXRAMET XR 10/500MG TABLET 7'S?Arrow

  • If you miss a dose of OXRAMET XR 10/500MG TABLET 7'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store OXRAMET XR 10/500MG TABLET 7'S?Arrow

  • Keep OXRAMET XR 10/500MG TAB 1X7 away from the reach of children and pets.
  • Store OXRAMET XR 10/500MG TAB 1X7 at room temperature.

Benefits of OXRAMET XR 10/500MG TABLET 7'SArrow

  • OXRAMET XR 10/500MG TABLET 7'S is a combination medicine specifically formulated to help manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients: Dapagliflozin and Metformin.
  • Dapagliflozin belongs to a class of drugs known as SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine. This process effectively lowers blood sugar levels.
  • Metformin, on the other hand, is a biguanide. It primarily works by decreasing the amount of glucose produced by the liver and improving the body's sensitivity to insulin. Insulin is a hormone that helps glucose get from your blood into your cells for energy. By making the body more responsive to insulin, Metformin helps lower blood sugar levels.
  • The combined action of Dapagliflozin and Metformin offers several key benefits in managing type 2 diabetes. Firstly, it provides dual action in controlling blood sugar levels by targeting different mechanisms in the body. This can lead to more effective blood sugar control compared to using either medication alone.
  • Secondly, Dapagliflozin may also contribute to weight loss in some individuals. Because it causes the body to eliminate excess glucose through urine, it also leads to a loss of calories. This effect, however, is not the primary reason for using OXRAMET XR, and any weight loss should be discussed with your doctor.
  • Thirdly, Metformin has been shown to have cardiovascular benefits. Studies suggest that it may reduce the risk of heart disease and stroke in people with type 2 diabetes. While OXRAMET XR is not specifically prescribed to prevent heart disease, the Metformin component offers this additional potential advantage.
  • Furthermore, OXRAMET XR is designed as an extended-release (XR) tablet. This means that the medication is released slowly into the body over a longer period, typically 24 hours. This can help to maintain more stable blood sugar levels throughout the day and may reduce the frequency of side effects compared to immediate-release formulations.
  • By effectively controlling blood sugar levels, OXRAMET XR helps to reduce the risk of long-term complications associated with diabetes, such as kidney damage, nerve damage (neuropathy), eye damage (retinopathy), and foot problems. Maintaining stable blood sugar is crucial for overall health and well-being in individuals with type 2 diabetes.
  • In summary, OXRAMET XR 10/500MG TABLET 7'S offers a comprehensive approach to managing type 2 diabetes by combining the blood sugar-lowering effects of Dapagliflozin and Metformin. It helps to improve glycemic control, potentially aids in weight management, may offer cardiovascular benefits, and reduces the risk of diabetes-related complications. As always, this medication should be used in conjunction with a healthy diet and regular exercise, and under the guidance of a healthcare professional.

How to use OXRAMET XR 10/500MG TABLET 7'SArrow

  • OXRAMET XR 10/500MG TABLET 7'S is designed for oral administration. It should be taken exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water. This medication is best taken with food to minimize gastrointestinal side effects such as nausea or stomach upset.
  • The typical starting dose and frequency will be determined by your physician based on your individual needs and medical condition. It is crucial to adhere to the prescribed dosage and timing. Do not exceed the recommended dose, and do not discontinue the medication without consulting your doctor, as this could lead to uncontrolled blood sugar levels.
  • Consistency is key when taking OXRAMET XR. Try to take it at the same time each day to help you remember. If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking OXRAMET XR, it's important to monitor your blood sugar levels regularly, as directed by your healthcare provider. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Lifestyle modifications, such as diet and exercise, are essential for managing diabetes effectively and should be followed in conjunction with medication.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they can interact with OXRAMET XR. Pay close attention to any potential side effects and report them to your doctor promptly. Regular check-ups with your doctor are necessary to monitor your overall health and ensure the medication is working effectively. Store this medication at room temperature, away from moisture and heat, and keep it out of reach of children.

Quick Tips for OXRAMET XR 10/500MG TABLET 7'SArrow

  • Take Oxramet XR 10/500mg Tablet exactly as prescribed by your doctor. Do not crush, chew, or break the tablet, swallow it whole with a glass of water. It is usually taken once or twice daily with meals to minimize stomach upset and help regulate blood sugar levels effectively.
  • Consistency is key! Take Oxramet XR 10/500mg Tablet at the same time(s) each day to maintain a steady level of medication in your bloodstream. Setting a daily reminder can significantly improve adherence to your prescribed schedule and optimize its therapeutic effect.
  • Follow your diet and exercise plan. Oxramet XR 10/500mg Tablet is most effective when combined with a balanced diet and regular physical activity. Work closely with your healthcare provider or a registered dietitian to create a personalized plan that complements your medication and supports your overall health goals.
  • Monitor your blood sugar levels regularly, as directed by your healthcare provider. Keeping a detailed record of your blood glucose readings will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Share this information during your regular check-ups.
  • Be aware of potential side effects. Common side effects of Oxramet XR 10/500mg Tablet may include nausea, diarrhea, or stomach upset. If these side effects persist or become bothersome, consult your doctor promptly. Report any serious side effects, such as signs of lactic acidosis (e.g., muscle cramps, difficulty breathing), immediately to your healthcare provider. Stay hydrated and avoid excessive alcohol consumption while taking this medication.

Food Interactions with OXRAMET XR 10/500MG TABLET 7'SArrow

  • OXRAMET XR 10/500MG TABLET 7'S can be taken with or without food, but it is generally recommended to take it with food to minimize gastrointestinal side effects such as nausea or upset stomach.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis and may also affect blood sugar control. Consult your doctor for specific advice.
  • There are no specific food restrictions while taking OXRAMET XR 10/500MG TABLET 7'S unless otherwise directed by your doctor. Follow a balanced diet as part of your overall diabetes management plan.

FAQs

What is OXRAMET XR 10/500MG TABLET 7'S?Arrow

OXRAMET XR 10/500MG TABLET 7'S is a medication used to treat type 2 diabetes. It contains two medicines: Dapagliflozin and Metformin.

What is OXRAMET XR 10/500MG TABLET 7'S used for?Arrow

OXRAMET XR 10/500MG TABLET 7'S is used to control high blood sugar levels in people with type 2 diabetes. This medicine is used along with diet and exercise.

How does OXRAMET XR 10/500MG TABLET 7'S work?Arrow

OXRAMET XR 10/500MG TABLET 7'S works in two ways. Dapagliflozin lowers blood sugar levels by removing excess sugar from the kidneys. Metformin works by reducing the amount of sugar produced by the liver and improving the body's sensitivity to insulin.

What are the common side effects of OXRAMET XR 10/500MG TABLET 7'S?Arrow

Common side effects of OXRAMET XR 10/500MG TABLET 7'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

How should I store OXRAMET XR 10/500MG TABLET 7'S?Arrow

Store OXRAMET XR 10/500MG TABLET 7'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can OXRAMET XR 10/500MG TABLET 7'S cause weight loss?Arrow

Some patients may experience weight loss with OXRAMET XR 10/500MG TABLET 7'S, but it is not a common side effect.

Is OXRAMET XR 10/500MG TABLET 7'S harmful to the kidneys?Arrow

OXRAMET XR 10/500MG TABLET 7'S can be harmful to people with kidney problems. Talk to your doctor before taking this medicine if you have kidney disease.

Can I drink alcohol while taking OXRAMET XR 10/500MG TABLET 7'S?Arrow

You should avoid drinking alcohol while taking OXRAMET XR 10/500MG TABLET 7'S as it can increase the risk of side effects.

What happens if I miss a dose of OXRAMET XR 10/500MG TABLET 7'S?Arrow

If you miss a dose of OXRAMET XR 10/500MG TABLET 7'S, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Is OXRAMET XR 10/500MG TABLET 7'S safe during pregnancy?Arrow

The safety of OXRAMET XR 10/500MG TABLET 7'S during pregnancy has not been established. Talk to your doctor before taking this medicine if you are pregnant or planning to become pregnant.

What should I tell my doctor before taking OXRAMET XR 10/500MG TABLET 7'S?Arrow

Before taking OXRAMET XR 10/500MG TABLET 7'S, tell your doctor about all your medical conditions, allergies, and all the medications you are taking.

Can OXRAMET XR 10/500MG TABLET 7'S interact with other medications?Arrow

OXRAMET XR 10/500MG TABLET 7'S can interact with certain other medications. Tell your doctor about all the medications you are taking, including prescription and over-the-counter drugs.

What to do in case of overdose of Oxramet XR 10/500mg Tablet 7'S?Arrow

In case of an overdose of Oxramet XR 10/500mg Tablet 7'S, contact a doctor immediately or go to the nearest hospital.

Is Oxramet XR 10/500mg Tablet 7'S safe for children?Arrow

Oxramet XR 10/500mg Tablet 7'S is not recommended for children, as its safety and efficacy have not been established.

What foods should I avoid while taking Oxramet XR 10/500mg Tablet 7'S?Arrow

While taking Oxramet XR 10/500mg Tablet 7'S, it is advisable to avoid foods high in sugar and simple carbohydrates.

What is the composition of Oxramet XR 10/500MG Tablet 7's?Arrow

Oxramet XR 10/500MG Tablet 7's contains Dapagliflozin 10 MG + Metformin Hydrochloride 500 MG Sustained Release. It is a SGLT2 inhibitor; and biguanide antidiabetic.

What are the side effects of Oxramet XR 10/500MG Tablet 7's?Arrow

Commonly reported side effects of Oxramet XR 10/500MG Tablet 7's include genital fungal infections, urinary tract infections, increased urination, thirst, dehydration; and diarrhoea, nausea, abdominal discomfort, metallic taste, loss of appetite — often improve with time or when taken with food. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Oxramet XR 10/500MG Tablet 7's?Arrow

Oxramet XR 10/500MG Tablet 7's is listed at Rs. 108.8 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Oxramet XR 10/500MG Tablet 7's?Arrow

Risk of euglycaemic diabetic ketoacidosis — ketones may be raised with near-normal glucose; seek care for nausea, vomiting or abdominal pain; and Rare but serious risk of lactic acidosis, particularly with kidney impairment, dehydration, acute illness or excess alcohol. Tell your doctor about all other medicines you take before starting Oxramet XR 10/500MG Tablet 7's.

What is the correct dosage of Oxramet XR 10/500MG Tablet 7's?Arrow

The dose of Oxramet XR 10/500MG Tablet 7's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Oxramet XR 10/500MG Tablet 7's?Arrow

A generic medicine is one with the same active composition as the branded product — for Oxramet XR 10/500MG Tablet 7's that is Dapagliflozin 10 MG + Metformin Hydrochloride 500 MG Sustained Release. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Oxramet XR 10/500MG Tablet 7's.

Is Oxramet XR 10/500MG Tablet 7's a prescription medicine?Arrow

Yes. Oxramet XR 10/500MG Tablet 7's requires a valid doctor's prescription.

Who is the manufacturer of Oxramet XR 10/500MG Tablet 7's?Arrow

Oxramet XR 10/500MG Tablet 7's is manufactured by Sun Pharmaceutical Industries Ltd.

What is the dosage form of Oxramet XR 10/500MG Tablet 7's?Arrow

Oxramet XR 10/500MG Tablet 7's is supplied as a tablet and is taken by the oral route.

What are the benefits of Oxramet XR 10/500MG Tablet 7's?Arrow

Oxramet XR 10/500MG Tablet 7's contains Dapagliflozin 10 MG + Metformin Hydrochloride 500 MG Sustained Release. It is used for type 2 diabetes mellitus; also used in heart failure and chronic kidney disease in selected patients; and first-line management of type 2 diabetes mellitus, usually alongside diet and exercise. The benefit you get depends on the condition your doctor prescribed Oxramet XR 10/500MG Tablet 7's for.

Is Oxramet XR 10/500MG Tablet 7's safe to take daily?Arrow

Whether Oxramet XR 10/500MG Tablet 7's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Oxramet XR 10/500MG Tablet 7's on your own.

When should Oxramet XR 10/500MG Tablet 7's be taken — morning or night?Arrow

The timing of Oxramet XR 10/500MG Tablet 7's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Oxramet XR 10/500MG Tablet 7's without a doctor's consultation?Arrow

No. Oxramet XR 10/500MG Tablet 7's is a prescription medicine and should only be taken on a doctor's advice.

Can Oxramet XR 10/500MG Tablet 7's be taken during pregnancy or breastfeeding?Arrow

Do not take Oxramet XR 10/500MG Tablet 7's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

How should Oxramet XR 10/500MG Tablet 7's be stored?Arrow

Store Oxramet XR 10/500MG Tablet 7's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

Book Icon

DrugBank: Metformin hydrochloride and dapagliflozin combination product.

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FDA Prescribing Information for XIGDUO XR (dapagliflozin and metformin hydrochloride extended-release) tablets, for oral use.

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European Medicines Agency (EMA) assessment report for Xigduo (dapagliflozin/metformin).

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Dapagliflozin and Metformin XR Fixed-Dose Combination: Efficacy and Safety in Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control with Metformin.

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Efficacy and safety of dapagliflozin add-on to metformin in Asian patients with type 2 diabetes mellitus.

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RxList: XIGDUO XR drug information.

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DailyMed: XIGDUO XR label information.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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