JUSTOZA M 10/500MG TABLET 10'S
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JUSTOZA M 10/500MG TABLET 10'S
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JUSTOZA M 10/500MG TABLET 10'S

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JUSTOZA M 10/500MG TABLET 10'S

By MANKIND PHARMA LIMITED

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164.29

₹139.65

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About JUSTOZA M 10/500MG TABLET 10'S

  • JUSTOZA M 10/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels in adults when diet and exercise alone are not enough. This medication works by increasing the release of insulin from the pancreas and decreasing the amount of glucose produced by the liver. It also improves the body's response to insulin.
  • The 'JUSTOZA M 10/500MG' formulation contains two active ingredients: Sitagliptin and Metformin. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors, which work by increasing incretin levels. Incretins help the body produce more insulin when blood sugar is high and reduce the amount of glucose produced by the liver. Metformin, on the other hand, is a biguanide that decreases glucose production in the liver and improves insulin sensitivity in the body's tissues. The combination of these two medications provides a synergistic effect in controlling blood sugar levels.
  • This tablet is usually taken once or twice daily with meals to minimize gastrointestinal side effects. Dosage is determined by your doctor based on your medical condition and response to treatment. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. It's important to maintain a healthy diet and exercise regularly while taking this medication to maximize its benefits.
  • JUSTOZA M 10/500MG TABLET should be used with caution in patients with kidney or liver disease and is not recommended for patients with severe kidney problems. Before taking this medication, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal products, and supplements. Regular monitoring of kidney function and blood sugar levels is essential during treatment. It is also important to be aware of the symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) and know how to manage them.
  • This medicine is a prescription medication and should be taken under the guidance of a healthcare professional. It is important to follow your doctor's instructions carefully and not to adjust the dosage or stop taking the medication without consulting your doctor. Consistent use of JUSTOZA M 10/500MG TABLET, along with lifestyle modifications, can significantly improve blood sugar control and reduce the risk of diabetes-related complications.

Uses of JUSTOZA M 10/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improving blood sugar control
  • Management of insulin resistance associated with polycystic ovary syndrome (PCOS)

How JUSTOZA M 10/500MG TABLET 10'S Works

  • JUSTOZA M 10/500MG TABLET is a combination medication containing Metformin and Sitagliptin, designed to manage blood sugar levels in individuals with type 2 diabetes. To understand how it works, we need to break down the actions of each of its active ingredients.
  • Metformin, a biguanide, primarily reduces glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver creates glucose from non-carbohydrate sources. Secondly, Metformin enhances insulin sensitivity in peripheral tissues, such as muscles. This allows cells to absorb and utilize glucose more effectively, lowering blood sugar levels. Additionally, Metformin slows down the absorption of glucose from the intestines after a meal, preventing rapid spikes in blood sugar.
  • Sitagliptin, on the other hand, belongs to a class of drugs called DPP-4 inhibitors. DPP-4 (dipeptidyl peptidase-4) is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar levels. They stimulate insulin release from the pancreas when blood sugar is high and suppress glucagon secretion, which reduces glucose production in the liver. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body, leading to improved insulin secretion and reduced glucagon levels, ultimately lowering blood sugar.
  • In summary, JUSTOZA M combines the actions of Metformin, which reduces glucose production in the liver and enhances insulin sensitivity, with Sitagliptin, which increases incretin hormone levels to boost insulin secretion and suppress glucagon. This dual mechanism helps to effectively control blood sugar levels in people with type 2 diabetes, especially when diet and exercise alone are not sufficient. This synergistic effect of the two medications helps to maintain stable blood sugar levels throughout the day, reducing the risk of hyperglycemia (high blood sugar) and its associated complications.
  • It is important to take JUSTOZA M as prescribed by your doctor and to follow their recommendations regarding diet, exercise, and regular blood sugar monitoring. Consistent adherence to the treatment plan is crucial for achieving optimal blood sugar control and preventing long-term complications of diabetes.

Side Effects of JUSTOZA M 10/500MG TABLET 10'SArrow

Possible side effects of JUSTOZA M 10/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, weakness, fatigue, upper respiratory tract infection, urinary tract infection, skin rash, itching, constipation, flatulence, and in rare cases, lactic acidosis or vitamin B12 deficiency. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for JUSTOZA M 10/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it or any of its ingredients.

Dosage of JUSTOZA M 10/500MG TABLET 10'SArrow

  • The recommended dosage of JUSTOZA M 10/500MG TABLET 10'S varies depending on individual patient needs, blood glucose levels, and response to treatment. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Generally, the starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. Your physician may gradually increase the dosage based on your glycemic control, up to a maximum of two tablets twice daily.
  • The tablets should be swallowed whole with a glass of water and not crushed, chewed, or broken. Consistency in timing is essential for maintaining stable blood glucose levels. For instance, if you are prescribed one tablet in the morning and one in the evening, take them at approximately the same time each day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
  • It's important to regularly monitor your blood glucose levels as directed by your doctor, especially when starting JUSTOZA M 10/500MG TABLET 10'S or when the dosage is adjusted. This will help assess the effectiveness of the medication and guide further dosage adjustments. Factors such as diet, exercise, and stress can influence your blood glucose levels and may necessitate changes in your medication regimen. Always consult your doctor before making any changes to your dosage.
  • Take 'JUSTOZA M 10/500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of JUSTOZA M 10/500MG TABLET 10'S?Arrow

  • If you miss a dose of JUSTOZA M 10/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store JUSTOZA M 10/500MG TABLET 10'S?Arrow

  • Keep JUSTOZA M 10/500MG TAB 1X10 away from the reach of children and pets.
  • Store JUSTOZA M 10/500MG TAB 1X10 at room temperature.

Benefits of JUSTOZA M 10/500MG TABLET 10'SArrow

  • JUSTOZA M 10/500MG TABLET 10'S is a combination medicine primarily used to manage type 2 diabetes mellitus, a condition characterized by high blood sugar levels. It effectively lowers blood glucose by targeting multiple mechanisms in the body, offering a comprehensive approach to diabetes management.
  • This medication combines two active ingredients: sitagliptin and metformin. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors, which work by increasing the levels of incretin hormones in the body. Incretin hormones help stimulate the release of insulin after a meal and reduce the amount of glucose produced by the liver. Metformin, on the other hand, is a biguanide that decreases glucose production in the liver, improves insulin sensitivity in muscle cells, and reduces glucose absorption from the intestines.
  • By combining these two medications, JUSTOZA M 10/500MG TABLET 10'S provides several key benefits for individuals with type 2 diabetes. Firstly, it helps to effectively control blood sugar levels throughout the day and night. This is crucial for preventing long-term complications of diabetes, such as heart disease, kidney disease, nerve damage, and vision problems.
  • Secondly, JUSTOZA M 10/500MG TABLET 10'S can improve insulin sensitivity. Insulin resistance is a common problem in type 2 diabetes, where the body's cells do not respond properly to insulin. By increasing insulin sensitivity, this medication allows insulin to work more effectively, helping glucose enter cells and be used for energy.
  • Thirdly, JUSTOZA M 10/500MG TABLET 10'S helps to reduce the risk of hypoglycemia (low blood sugar) compared to some other diabetes medications. Sitagliptin's mechanism of action is glucose-dependent, meaning it only stimulates insulin release when blood sugar levels are high. This reduces the likelihood of excessive insulin release and subsequent hypoglycemia. Metformin, when used alone, rarely causes hypoglycemia.
  • Fourthly, JUSTOZA M 10/500MG TABLET 10'S may contribute to weight management. Metformin is often associated with modest weight loss or weight stabilization, which can be beneficial for individuals with type 2 diabetes who are often overweight or obese. While sitagliptin is generally weight-neutral, the combination with metformin can help in managing weight.
  • Fifthly, JUSTOZA M 10/500MG TABLET 10'S is convenient to use, as it is a once- or twice-daily oral medication. This can improve adherence to treatment compared to medications that require multiple daily doses or injections.
  • Finally, JUSTOZA M 10/500MG TABLET 10'S has demonstrated efficacy in clinical trials, showing significant reductions in HbA1c (a measure of average blood sugar levels over 2-3 months). This provides confidence in its ability to effectively manage type 2 diabetes.
  • In summary, JUSTOZA M 10/500MG TABLET 10'S offers a multifaceted approach to managing type 2 diabetes by controlling blood sugar levels, improving insulin sensitivity, reducing the risk of hypoglycemia, potentially aiding in weight management, and providing a convenient oral administration. Regular monitoring by a healthcare professional is crucial to assess its effectiveness and adjust treatment as needed.

How to use JUSTOZA M 10/500MG TABLET 10'SArrow

  • JUSTOZA M 10/500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It contains Sitagliptin and Metformin as active ingredients. It works by increasing the release of insulin from the pancreas and decreasing glucose production in the liver, ultimately helping to lower blood sugar levels.
  • Always take JUSTOZA M 10/500MG TABLET 10'S exactly as your doctor has told you. The usual dose is one tablet twice daily, preferably with meals to reduce gastrointestinal side effects. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
  • It is important to take JUSTOZA M 10/500MG TABLET 10'S at the same time each day to maintain a consistent level of medication in your body. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Follow your doctor's instructions regarding diet and exercise while taking JUSTOZA M 10/500MG TABLET 10'S. This medicine works best when combined with a healthy lifestyle. Regularly monitor your blood sugar levels as directed by your doctor. Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking to avoid potential drug interactions.
  • If you experience any side effects, such as nausea, vomiting, diarrhea, or abdominal pain, consult your doctor immediately. It's also crucial to be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shakiness, rapid heartbeat, and confusion. Carry a source of sugar with you, like candy or glucose tablets, in case of a hypoglycemic episode. Contact your doctor immediately if you have any concerns about your health condition or medication.

Quick Tips for JUSTOZA M 10/500MG TABLET 10'SArrow

  • Take JUSTOZA M 10/500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this can affect your blood sugar control.
  • JUSTOZA M 10/500MG TABLET 10'S is most effective when taken with meals. This helps to reduce the risk of stomach upset and also improves the absorption of the medication. Try to take it at the same time each day to maintain consistent blood sugar levels.
  • Monitor your blood sugar levels regularly while taking JUSTOZA M 10/500MG TABLET 10'S. Keep a record of your readings and share them with your doctor during your check-ups. This will help your doctor adjust your dosage if needed and ensure optimal blood sugar control.
  • Follow a healthy diet and exercise regularly while taking JUSTOZA M 10/500MG TABLET 10'S. This medication works best when combined with lifestyle changes like a balanced diet low in sugar and regular physical activity. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Be aware of the symptoms of low blood sugar (hypoglycemia) such as sweating, shaking, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times. If you experience symptoms of hypoglycemia, consume the fast-acting sugar immediately and inform your doctor.

Food Interactions with JUSTOZA M 10/500MG TABLET 10'SArrow

  • Follow a balanced and healthy diet recommended by your doctor or a registered dietitian.

FAQs

What is Justoza M 10/500mg Tablet 10's and what is it used for?Arrow

Justoza M 10/500mg Tablet 10's is a medication containing saxagliptin and metformin. It is used to control high blood sugar levels in people with type 2 diabetes.

How does Justoza M 10/500mg Tablet 10's work?Arrow

Justoza M 10/500mg Tablet 10's works in two ways: saxagliptin works by increasing insulin release and decreasing glucose production, while metformin increases the body's sensitivity to insulin and decreases the amount of glucose made by the liver.

What are the common side effects of Justoza M 10/500mg Tablet 10's?Arrow

Common side effects of Justoza M 10/500mg Tablet 10's include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is Justoza M 10/500mg Tablet 10's safe for people with kidney problems?Arrow

Justoza M 10/500mg Tablet 10's should be used with caution in people with kidney problems, as it can worsen kidney problems. Talk to your doctor if you have a history of kidney disease.

Is Justoza M 10/500mg Tablet 10's safe during pregnancy?Arrow

The safety of Justoza M 10/500mg Tablet 10's during pregnancy is not established. Talk to your doctor if you are pregnant or planning to become pregnant.

How to store Justoza M 10/500mg Tablet 10's?Arrow

Store Justoza M 10/500mg Tablet 10's at room temperature, away from heat and moisture.

Can Justoza M 10/500mg Tablet 10's interact with other medications?Arrow

Yes, Justoza M 10/500mg Tablet 10's can interact with certain other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.

Does Justoza M 10/500mg Tablet 10's cause weight gain?Arrow

Justoza M 10/500mg Tablet 10's is not likely to cause weight gain.

Can Justoza M 10/500mg Tablet 10's be taken with or without food?Arrow

It is recommended to take Justoza M 10/500mg Tablet 10's with food to minimize the chance of stomach upset.

What to do if I miss a dose of Justoza M 10/500mg Tablet 10's?Arrow

If you miss a dose of Justoza M 10/500mg Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I drink alcohol while taking Justoza M 10/500mg Tablet 10's?Arrow

It is not recommended to drink alcohol while taking Justoza M 10/500mg Tablet 10's, as it can increase the risk of low blood sugar.

What are other brands containing Metformin?Arrow

Some other brands containing Metformin include Glucophage, Fortamet and Riomet.

Can I suddenly stop taking Justoza M 10/500mg Tablet 10's?Arrow

Do not stop taking Justoza M 10/500mg Tablet 10's suddenly. Always take it as directed by your doctor.

What are some other medications containing Saxagliptin?Arrow

Other medications containing Saxagliptin include Onglyza.

What happens if I overdose on Justoza M 10/500mg Tablet 10's?Arrow

If you suspect you have overdosed on Justoza M 10/500mg Tablet 10's, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, abdominal pain, and in severe cases, lactic acidosis.

References

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (n.d.). Retrieved from https://www.ema.europa.eu/en/documents/product-information/xigduo-epar-product-information_en.pdf

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf

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Marketer / Manufacturer Details

MANKIND PHARMA LIMITED

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India

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