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DAPALEX M 10/500MG TABLET 10'S

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DAPALEX M 10/500MG TABLET 10'S

By AJANTA PHARMA LIMITED

MRP

165

₹140.25

15 % OFF

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Tablet

10

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About DAPALEX M 10/500MG TABLET 10'S

  • DAPALEX M 10/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It combines two active ingredients: dapagliflozin and metformin, which work through different mechanisms to lower blood sugar levels. This medication is typically prescribed when diet and exercise alone are not sufficient to control blood glucose.
  • Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated through urine, effectively lowering blood sugar levels. Additionally, dapagliflozin may contribute to weight loss and provide some cardiovascular benefits.
  • Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves the body's sensitivity to insulin. It helps insulin work more effectively, allowing cells to absorb glucose from the blood for energy. Metformin is a widely used and well-established medication for managing type 2 diabetes.
  • DAPALEX M 10/500MG TABLET is usually taken once or twice daily with meals to minimize gastrointestinal side effects. Common side effects may include nausea, diarrhea, and abdominal discomfort. It's important to stay hydrated while taking this medication, as dapagliflozin can increase the risk of dehydration. Regular monitoring of kidney function is also recommended. This medication helps to manage blood sugar levels effectively when combined with a healthy diet and regular physical activity. Always consult with your healthcare provider for personalized medical advice and to determine if DAPALEX M 10/500MG TABLET is right for you.

Uses of DAPALEX M 10/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Controlling blood sugar levels
  • Lowering high blood sugar
  • Improving insulin sensitivity
  • Reducing post-meal blood sugar levels
  • Helping to prevent kidney problems (due to diabetes)
  • Helping to prevent blindness (due to diabetes)
  • Helping to prevent nerve problems (due to diabetes)
  • Helping to prevent heart attacks or strokes (due to diabetes)

How DAPALEX M 10/500MG TABLET 10'S Works

  • DAPALEX M 10/500MG TABLET is a combination medication containing Dapagliflozin and Metformin, designed to manage blood sugar levels in adults with type 2 diabetes. It works through complementary mechanisms to improve glycemic control. Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. SGLT2 inhibitors work in the kidneys by blocking the reabsorption of glucose back into the bloodstream, increasing glucose excretion in the urine. By reducing the amount of glucose reabsorbed by the kidneys, Dapagliflozin helps lower blood sugar levels.
  • Metformin, on the other hand, is a biguanide that primarily works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. It reduces hepatic glucose output by inhibiting gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin enhances insulin sensitivity in peripheral tissues like muscles, allowing them to utilize glucose more effectively. This combined action of Dapagliflozin and Metformin helps to lower both fasting and post-meal blood sugar levels.
  • In essence, DAPALEX M 10/500MG TABLET leverages the actions of Dapagliflozin to remove excess glucose via the kidneys, while Metformin reduces glucose production in the liver and enhances the body's response to insulin. This dual-pronged approach effectively manages blood sugar levels, reducing the risk of diabetes-related complications. It is crucial to use this medication as prescribed by your healthcare provider, in conjunction with diet and exercise, to achieve optimal blood sugar control and overall health benefits. Regular monitoring of blood sugar levels is also essential to ensure the medication is working effectively and to adjust the treatment plan as needed.
  • Furthermore, DAPALEX M offers additional benefits beyond blood sugar control. Dapagliflozin has been shown to have positive effects on weight management and cardiovascular health. By increasing glucose excretion, it can contribute to modest weight loss. Studies have also indicated that Dapagliflozin may reduce the risk of heart failure and cardiovascular death in individuals with type 2 diabetes and established cardiovascular disease. Metformin, too, has been associated with potential cardiovascular benefits, making DAPALEX M a comprehensive treatment option for managing diabetes and related health risks. The combination therapy addresses multiple aspects of diabetes management, providing a holistic approach to patient care.

Side Effects of DAPALEX M 10/500MG TABLET 10'SArrow

DAPALEX M 10/500MG TABLET 10'S may cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and metallic taste. Some individuals might experience hypoglycemia (low blood sugar), characterized by symptoms like sweating, dizziness, tremor, rapid heartbeat, hunger, blurred vision, headache, or weakness. Skin reactions such as rash, itching, and redness can occur. Less common but potentially serious side effects include lactic acidosis (symptoms: deep and rapid breathing, nausea, vomiting, stomach pain), and kidney problems. Allergic reactions, although rare, can manifest as swelling of the face, lips, tongue, or throat, and difficulty breathing. Other possible side effects are vitamin B12 deficiency, joint pain, and upper respiratory tract infection. Consult your doctor if you experience any persistent or worsening side effects.

Safety Advice for DAPALEX M 10/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use if you are allergic to dapagliflozin, metformin, or any of the ingredients in DAPALEX M 10/500MG TABLET 10'S.

Dosage of DAPALEX M 10/500MG TABLET 10'SArrow

  • The recommended dosage of DAPALEX M 10/500MG TABLET 10'S varies depending on individual patient needs, blood glucose levels, and other medications you may be taking. Your doctor will determine the appropriate dosage for you. Generally, the starting dose is one tablet once or twice daily. It's crucial to adhere to your doctor's prescribed dosage and timing.
  • DAPALEX M 10/500MG TABLET 10'S should be swallowed whole with a glass of water, preferably with meals to reduce the likelihood of gastrointestinal side effects. Do not crush, chew, or break the tablet. Consistency in taking your medication at the same time(s) each day helps maintain stable blood glucose levels and improves the effectiveness of the medication.
  • If you miss a dose of DAPALEX M 10/500MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one, as this can increase the risk of side effects. It is recommended to set a daily alarm so that you don't miss taking the medicine. Regular monitoring of blood sugar levels is advised, as directed by your healthcare provider, to assess the effectiveness of the treatment and make necessary dosage adjustments.
  • It is important to remember that DAPALEX M 10/500MG TABLET 10'S is part of a comprehensive treatment plan for diabetes, which also includes diet and exercise. Follow your doctor's recommendations for diet and exercise carefully. Changes in your diet, activity level, or other medications can affect your blood glucose control and may require adjustments to your DAPALEX M 10/500MG TABLET 10'S dosage.
  • Take 'DAPALEX M 10/500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DAPALEX M 10/500MG TABLET 10'S?Arrow

  • If you miss a dose of DAPALEX M 10/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store DAPALEX M 10/500MG TABLET 10'S?Arrow

  • Keep DAPALEX M 10/500MG TAB 1X10 away from the reach of children and pets.
  • Store DAPALEX M 10/500MG TAB 1X10 at room temperature.

Benefits of DAPALEX M 10/500MG TABLET 10'SArrow

  • DAPALEX M 10/500MG TABLET 10'S is a combination medication designed to effectively manage blood sugar levels in individuals diagnosed with type 2 diabetes mellitus. This dual-action tablet combines dapagliflozin and metformin, working through complementary mechanisms to provide comprehensive glycemic control and offering several key benefits for patients.
  • One of the primary benefits of DAPALEX M is its ability to lower blood sugar levels by targeting multiple pathways. Dapagliflozin, an SGLT2 inhibitor, works in the kidneys to prevent glucose reabsorption, allowing excess glucose to be excreted through urine. Metformin, a biguanide, reduces glucose production in the liver and improves insulin sensitivity in the body. This synergistic action ensures more effective blood sugar management compared to using either medication alone.
  • Improved glycemic control translates to several positive outcomes. By maintaining stable blood sugar levels, DAPALEX M helps reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, kidney damage (nephropathy), nerve damage (neuropathy), and eye damage (retinopathy). Consistent glycemic control also contributes to improved energy levels and overall well-being.
  • Dapagliflozin, a component of DAPALEX M, has demonstrated cardiovascular benefits in clinical trials. It can help reduce the risk of heart failure and cardiovascular death in patients with type 2 diabetes who also have established cardiovascular disease or multiple cardiovascular risk factors. This added advantage makes DAPALEX M a valuable option for patients concerned about heart health.
  • Metformin, another component of DAPALEX M, has been shown to promote modest weight loss or weight management in some individuals. Unlike some other diabetes medications that can lead to weight gain, metformin helps improve insulin sensitivity without significantly increasing appetite or promoting fat storage. This can be particularly beneficial for overweight or obese patients with type 2 diabetes.
  • DAPALEX M offers the convenience of a single tablet containing two active ingredients, simplifying medication management and improving adherence. This fixed-dose combination reduces the pill burden for patients who would otherwise need to take multiple medications separately, making it easier to stick to their prescribed treatment plan. Improved adherence leads to better glycemic control and overall health outcomes.
  • Beyond glycemic control and cardiovascular benefits, DAPALEX M can also have a positive impact on kidney health. Dapagliflozin has been shown to slow the progression of kidney disease in some patients with type 2 diabetes, particularly those with existing kidney damage. This protective effect on the kidneys makes DAPALEX M a valuable option for patients at risk of or with early-stage diabetic kidney disease.
  • DAPALEX M contributes to improved overall quality of life by effectively managing diabetes and its associated risks. By helping patients maintain stable blood sugar levels, protect their heart and kidneys, and manage their weight, this medication empowers individuals to live healthier, more active lives with fewer diabetes-related complications.

How to use DAPALEX M 10/500MG TABLET 10'SArrow

  • DAPALEX M 10/500MG TABLET 10'S is an oral medication and should be taken as directed by your doctor. It's typically prescribed to manage blood sugar levels in individuals with type 2 diabetes. The usual starting dose is one tablet once or twice daily, taken with meals to reduce the likelihood of stomach upset. However, your doctor will determine the appropriate dosage based on your individual needs and response to the medication. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Consistency is key for optimal results. Try to take DAPALEX M 10/500MG TABLET 10'S at the same time(s) each day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
  • During treatment with DAPALEX M 10/500MG TABLET 10'S, it's crucial to adhere to your prescribed diet and exercise program. This medication works best when combined with lifestyle modifications. Regularly monitor your blood sugar levels as directed by your healthcare provider, and keep them informed of any changes or unusual symptoms you experience. Common side effects may include nausea, vomiting, diarrhea, and headache. Report any severe or persistent side effects to your doctor immediately.
  • Store DAPALEX M 10/500MG TABLET 10'S at room temperature, away from moisture and heat. Keep the medication out of the reach of children. Before starting DAPALEX M 10/500MG TABLET 10'S, inform your doctor about any other medical conditions you have, especially kidney or liver problems, heart failure, or a history of pancreatitis. Also, disclose all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, as they may interact with DAPALEX M 10/500MG TABLET 10'S.
  • If you are planning to undergo surgery or any medical procedure, notify your doctor that you are taking DAPALEX M 10/500MG TABLET 10'S. It's essential to follow your doctor's instructions carefully and attend all scheduled appointments to ensure the safe and effective use of this medication.

Quick Tips for DAPALEX M 10/500MG TABLET 10'SArrow

  • Take DAPALEX M 10/500MG TABLET 10'S as prescribed by your doctor, usually once or twice daily, with meals to minimize stomach upset and maintain consistent blood sugar levels. It's crucial to follow your doctor's dosage instructions precisely and avoid exceeding the recommended dose.
  • DAPALEX M combines two medications: dapagliflozin and metformin. Dapagliflozin helps your kidneys remove sugar from your body through urine, while metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action effectively lowers blood sugar levels in individuals with type 2 diabetes.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider. Keep a record of your readings and share them with your doctor during appointments. This will help them assess how well the medication is working and adjust your treatment plan if necessary. Discuss target blood sugar ranges with your doctor.
  • Stay well-hydrated while taking DAPALEX M, as dapagliflozin can increase urination. Drinking plenty of water helps prevent dehydration. Also, be aware of the symptoms of dehydration, such as dizziness, lightheadedness, and dark urine, and consult your doctor if you experience these.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting DAPALEX M. This is important to avoid potential drug interactions. Pay special attention to medications that affect blood sugar levels, kidney function, or blood pressure.
  • Maintain a healthy lifestyle by following a balanced diet, engaging in regular physical activity, and managing your weight. These lifestyle modifications can significantly improve blood sugar control and overall health in individuals with type 2 diabetes. Consult a registered dietitian or certified diabetes educator for personalized guidance.
  • Be aware of potential side effects, such as urinary tract infections, yeast infections (especially in women), nausea, diarrhea, and hypoglycemia (low blood sugar). Report any persistent or bothersome side effects to your doctor promptly. Carry a source of fast-acting glucose, such as glucose tablets or juice, to treat hypoglycemia.
  • If you are scheduled for surgery or any medical procedure involving contrast dye, inform your doctor that you are taking DAPALEX M. Metformin may need to be temporarily discontinued before the procedure to prevent kidney problems.
  • Store DAPALEX M in a cool, dry place, away from direct sunlight and moisture. Keep the medication out of reach of children. Properly dispose of any unused medication according to local regulations.
  • Attend regular check-ups with your doctor to monitor your kidney function, liver function, and overall health. These check-ups are essential for detecting any potential problems early and ensuring the safe and effective use of DAPALEX M. Don't skip scheduled appointments even if you feel well.

Food Interactions with DAPALEX M 10/500MG TABLET 10'SArrow

  • DAPALEX M 10/500MG TABLET 10'S is generally recommended to be taken with meals to help reduce gastrointestinal side effects. However, it is important to maintain a consistent dietary pattern while taking this medication. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis, a rare but serious side effect. Consult your doctor or pharmacist for specific dietary advice.

FAQs

What is DAPALEX M 10/500MG TABLET 10'S?Arrow

DAPALEX M 10/500MG TABLET 10'S is a combination of two medicines: Dapagliflozin and Metformin. It is used to control high blood sugar levels in people with type 2 diabetes.

What is DAPALEX M 10/500MG TABLET 10'S used for?Arrow

It is used to treat type 2 diabetes mellitus, especially when diet and exercise alone are not enough to control blood sugar levels.

What are the common side effects of DAPALEX M 10/500MG TABLET 10'S?Arrow

Common side effects include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is DAPALEX M 10/500MG TABLET 10'S safe for people with kidney problems?Arrow

People with kidney problems should consult a doctor before using DAPALEX M 10/500MG TABLET 10'S, as it may worsen kidney function.

Is DAPALEX M 10/500MG TABLET 10'S safe during pregnancy?Arrow

DAPALEX M 10/500MG TABLET 10'S is not recommended during pregnancy. Talk to your doctor if you are pregnant or planning to become pregnant.

How to store DAPALEX M 10/500MG TABLET 10'S?Arrow

Store DAPALEX M 10/500MG TABLET 10'S at room temperature, away from moisture and heat.

Should DAPALEX M 10/500MG TABLET 10'S be taken with food?Arrow

DAPALEX M 10/500MG TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day.

What happens if I miss a dose of DAPALEX M 10/500MG TABLET 10'S?Arrow

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Does DAPALEX M 10/500MG TABLET 10'S cause weight gain?Arrow

DAPALEX M 10/500MG TABLET 10'S does not usually cause weight gain. In fact, some people may experience weight loss.

Can DAPALEX M 10/500MG TABLET 10'S cause low blood sugar (hypoglycemia)?Arrow

DAPALEX M 10/500MG TABLET 10'S alone does not usually cause low blood sugar, but the risk of hypoglycemia increases when it is taken with other diabetes medications, such as insulin or sulfonylureas.

Which medications should not be taken with DAPALEX M 10/500MG TABLET 10'S?Arrow

Some medications can interact with DAPALEX M 10/500MG TABLET 10'S, including certain diuretics, corticosteroids, and thyroid medications. Talk to your doctor or pharmacist about potential interactions.

Is it safe to drink alcohol while taking DAPALEX M 10/500MG TABLET 10'S?Arrow

Drinking alcohol is not recommended while taking DAPALEX M 10/500MG TABLET 10'S, as it can increase the risk of low blood sugar and worsen the side effects of the medication.

Does DAPALEX M 10/500MG TABLET 10'S prevent heart disease?Arrow

DAPALEX M 10/500MG TABLET 10'S is primarily used to control blood sugar, but some studies have suggested it may also help reduce the risk of heart disease. Talk to your doctor to see if it's right for you.

Can I take DAPALEX M 10/500MG TABLET 10'S with other diabetes medications?Arrow

DAPALEX M 10/500MG TABLET 10'S can be taken with other diabetes medications, but it is important to talk to your doctor to make sure the combination is safe and does not increase the risk of low blood sugar.

What is another brand of Glimepiride and Metformin?Arrow

Another brand of Glimepiride and Metformin is Glimsave M. Always consult with your doctor or pharmacist for specific alternatives.

References

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Dapagliflozin - DrugBank Online. (Comprehensive information on Dapagliflozin including pharmacology, mechanism of action, and interactions)

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FARXIGA (dapagliflozin) prescribing information. (FDA label providing detailed information on Dapagliflozin)

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Forxiga - European Medicines Agency. (European Medicines Agency assessment report on Dapagliflozin)

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Dapagliflozin: a review of its use in the treatment of type 2 diabetes mellitus. (PMC - Detailed review of Dapagliflozin)

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Metformin - DrugBank Online. (Comprehensive information on Metformin including pharmacology, mechanism of action, and interactions)

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GLUCOPHAGE (metformin hydrochloride) prescribing information. (FDA label providing detailed information on Metformin)

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Glucophage - European Medicines Agency. (European Medicines Agency assessment report on Metformin)

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Metformin: an old but still the best treatment for type 2 diabetes? (PMC - Review of Metformin)

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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