DENOSTA 60MG INJECTION
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DENOSTA 60MG INJECTION
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DENOSTA 60MG INJECTION

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DENOSTA 60MG INJECTION

By SHILPA BIOSCIENCES PVT LTD

MRP

7500

₹7500

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Product DetailsArrow

About DENOSTA 60MG INJECTION

  • DENOSTA 60MG INJECTION contains Denosumab as its active ingredient. It is primarily used in the treatment of osteoporosis, a condition characterized by decreased bone density and increased risk of fractures. Additionally, it is prescribed to prevent skeletal-related events in individuals with certain cancers that have spread to the bones, such as multiple myeloma and bone metastases from solid tumors.
  • DENOSTA 60MG INJECTION functions by targeting and binding to RANK ligand, a protein that regulates the activity of osteoclasts, the cells responsible for bone resorption. By inhibiting RANK ligand, this medication reduces bone breakdown, leading to increased bone mineral density and a lower risk of fractures. Clinical studies have demonstrated its effectiveness in improving bone density in postmenopausal women with osteoporosis and in reducing the incidence of bone complications in cancer patients.
  • Patients with moderate renal impairment may require careful monitoring of their kidney function during treatment with DENOSTA 60MG INJECTION. It's crucial to maintain adequate calcium and vitamin D levels while on this medication, typically through supplementation. Individuals with a known hypersensitivity or allergic reaction to Denosumab or any of the excipients in the injection should not use it.
  • DENOSTA 60MG INJECTION is not indicated for use in children and adolescents under the age of 18. The safety and efficacy of this medication have not been established in pediatric populations. Caution should be exercised when prescribing this medication to individuals with pre-existing hypoparathyroidism, a condition characterized by abnormally low levels of parathyroid hormone, as it may exacerbate this condition.

Uses of DENOSTA 60MG INJECTION

  • Osteoporosis (a condition characterized by weakened bones, making them more susceptible to fractures)
  • Bone loss resulting from hormonal therapy in the treatment of breast or prostate cancer
  • Multiple myeloma (a type of cancer that affects plasma cells within the bone marrow)
  • Bone metastases (cancer that has spread from its primary location to the bones)

Side Effects of DENOSTA 60MG INJECTIONArrow

Like all medications, DENOSTA 60MG INJECTION can cause side effects, although not everyone who takes it will experience them. Serious side effects include osteonecrosis of the jaw (severe necrosis or death of jaw cells), atypical femoral fractures, and hypocalcemia (low blood calcium levels). Common side effects include injection site reactions, back pain, musculoskeletal pain, infections, abdominal pain, headache, and hypophosphatemia (low blood phosphate levels).

  • Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
  • Atypical femoral fractures
  • Hypocalcemia (low blood calcium levels)
  • Injection site reactions
  • Back pain
  • Musculoskeletal pain
  • Infections
  • Abdominal pain
  • Headache
  • Hypophosphatemia (low blood phosphate levels)

Safety Advice for DENOSTA 60MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

The safety of using DENOSTA 60MG INJECTION during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Dosage of DENOSTA 60MG INJECTIONArrow

  • DENOSTA 60MG INJECTION is administered via injection by qualified healthcare professionals. It is crucial that this medication is not self-administered. The precise dosage, frequency, and duration of treatment with DENOSTA 60MG INJECTION will be carefully determined by your healthcare provider, taking into account your specific medical condition, its severity, and your individual response to the treatment. They will also consider other factors such as your age, weight, and kidney function.
  • It is essential to adhere strictly to the dosage and schedule prescribed by your doctor. Do not attempt to adjust the dosage or discontinue treatment without consulting them first. Any changes to your treatment plan should be made only under the guidance and supervision of a healthcare professional. Regular monitoring and follow-up appointments with your doctor are necessary to assess the effectiveness of the treatment and to monitor for any potential side effects. Your doctor will use these appointments to make any necessary adjustments to your dosage or treatment plan.
  • If you have any questions or concerns regarding your DENOSTA 60MG INJECTION treatment, please do not hesitate to discuss them with your healthcare provider. They are the best resource for accurate and personalized information.

How to store DENOSTA 60MG INJECTION?Arrow

  • Keep DENOSTA 60MG INJ 1ML away from the reach of children and pets.
  • Store DENOSTA 60MG INJ 1ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of DENOSTA 60MG INJECTIONArrow

  • DENOSTA 60MG INJECTION offers significant therapeutic benefits aimed at reducing fracture risk, enhancing bone mineral density, and fostering overall bone health. This medication operates by specifically targeting RANK ligands, effectively inhibiting bone resorption – the process where bone tissue is broken down. By impeding this process, DENOSTA 60MG INJECTION actively contributes to strengthening bones, making them more resilient and less susceptible to fractures.
  • This is particularly crucial for individuals diagnosed with osteoporosis, a condition characterized by weakened bones, or for those identified as being at high risk of developing fractures. Moreover, DENOSTA 60MG INJECTION plays a vital role in increasing bone mineral density. Bone mineral density serves as a critical indicator of bone strength, reflecting the amount of minerals present in the bone tissue.
  • The combined therapeutic effects of fracture risk reduction and increased bone mineral density significantly contribute to improved bone health. This improvement translates to a decreased likelihood of fractures, empowering patients to maintain an active lifestyle and enhancing their overall quality of life. DENOSTA 60MG INJECTION supports skeletal integrity and promotes long-term well-being by maintaining bone strength and resilience.

How to use DENOSTA 60MG INJECTIONArrow

  • DENOSTA 60MG INJECTION is administered by qualified healthcare professionals, ensuring accurate dosage and safe delivery. It is not intended for self-administration.
  • The precise dosage and duration of treatment with DENOSTA 60MG INJECTION are carefully determined by your healthcare provider. These factors are customized based on your specific medical condition, its severity, and your individual response to the medication.
  • Your doctor will consider various factors such as your age, weight, kidney function and overall health when determining the optimal dose for you.
  • Adhering to the prescribed schedule and dosage is crucial for achieving the best possible therapeutic outcomes. Any deviations should only be made under the guidance of your doctor.
  • If you have any concerns about your treatment with DENOSTA 60MG INJECTION, please do not hesitate to discuss them with your healthcare provider. They are best equipped to address your questions and ensure you receive the appropriate care.

FAQs

Can DENOSTA 60MG INJECTION be used in patients with a history of cancer?Arrow

DENOSTA 60MG INJECTION is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.

Can DENOSTA 60MG INJECTION be used in patients with kidney problems?Arrow

DENOSTA 60MG INJECTION is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.

Can DENOSTA 60MG INJECTION be used as a treatment for osteoporosis in men?Arrow

Yes, DENOSTA 60MG INJECTION is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.

Can DENOSTA 60MG INJECTION be used in children and adolescents with osteoporosis?Arrow

DENOSTA 60MG INJECTION is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.

Can DENOSTA 60MG INJECTION be used in individuals with dental implants?Arrow

DENOSTA 60MG INJECTION use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess DENOSTA 60MG INJECTION's potential risks and benefits.

What Are the Side Effects of DENOSTA 60MG INJECTION?Arrow

DENOSTA 60MG INJECTION can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.

Does DENOSTA 60MG INJECTION interact with other drugs?Arrow

There are no known significant negative interactions of DENOSTA 60MG INJECTION with other drugs. However, it is always important to inform your healthcare provider about all the medications, vitamins, and herbal supplements you are taking to avoid any potential risks.

What advice should I follow while taking DENOSTA 60MG INJECTION?Arrow

Attend all scheduled appointments and follow-up visits to monitor your response to treatment and address any concerns or side effects. Tell your doctor about your medical history, previous infection, liver disease, and kidney disease. Inform your healthcare provider about any allergies or hypersensitivity reactions you may have. Seek immediate medical attention if you experience severe allergic reactions or other serious side effects. Additionally, DENOSTA 60MG INJECTION may affect calcium levels, so monitoring calcium levels and ensuring adequate calcium and vitamin D intake is important. Pregnant and breastfeeding women should consult a doctor before taking this medication. Avoid taking any vaccines during treatment. Regular dental examinations and good oral hygiene practices are recommended to minimize the risk of jaw osteonecrosis.

What molecule/combination is used for making DENOSTA 60MG INJECTION?Arrow

DENOSUMAB is the molecule/combination used for making DENOSTA 60MG INJECTION.

For what type of ailments/diseases/conditions is DENOSTA 60MG INJECTION prescribed?Arrow

DENOSTA 60MG INJECTION is prescribed for ailments/diseases/conditions related to Rheumatology and Orthopaedics.

References

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Amgen Ltd, Electronic medicines compendium (EMC)

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Amgen Manufacturing Limited, US Food and Drug Administration

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Amgen Manufacturing Limited, US Food and Drug Administration

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Marketer / Manufacturer Details

SHILPA BIOSCIENCES PVT LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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