ODENSOMAB 60MG INJECTION
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ODENSOMAB 60MG INJECTION
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ODENSOMAB 60MG INJECTION

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ODENSOMAB 60MG INJECTION

By LUPIN LIMITED

MRP

19600

₹10080

48.57 % OFF

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Composition

Product DetailsArrow

About ODENSOMAB 60MG INJECTION

  • ODENSOMAB 60MG INJECTION contains the active ingredient Denosumab. It is a prescription medication primarily used in the treatment of osteoporosis, a condition characterized by decreased bone density and increased risk of fractures. Additionally, it is used to prevent skeletal-related events, such as fractures and spinal cord compression, in patients with certain cancers that have spread to the bone, including multiple myeloma and bone metastases from solid tumors.
  • ODENSOMAB 60MG INJECTION functions by targeting and inhibiting a protein called RANK ligand (RANKL). RANKL is a key regulator of osteoclasts, the cells responsible for breaking down bone tissue. By blocking RANKL, this medication reduces osteoclast activity, thereby decreasing bone resorption and increasing bone density. Clinical trials have demonstrated that it can significantly improve bone mineral density and reduce the risk of vertebral and non-vertebral fractures in postmenopausal women with osteoporosis and in individuals experiencing bone loss due to cancer treatments. Furthermore, ODENSOMAB 60MG INJECTION offers a targeted approach to managing bone health, providing a valuable option for patients at risk of fractures and other skeletal complications. Regular monitoring of kidney function is advisable, especially in patients with moderate renal impairment, to ensure safety and efficacy of the treatment.
  • Before using ODENSOMAB 60MG INJECTION, it's crucial to inform your healthcare provider about any pre-existing medical conditions, especially hypocalcemia (low calcium levels in the blood) or kidney problems. This medication is contraindicated in individuals with a known hypersensitivity or allergic reaction to Denosumab or any of its components. To prevent hypocalcemia, it is essential to maintain adequate calcium and vitamin D intake during treatment. ODENSOMAB 60MG INJECTION is not recommended for use in children and adolescents under the age of 18 due to the lack of established safety and efficacy data in this population. Caution should be exercised when administering this medication to individuals with pre-existing hypoparathyroidism, a condition characterized by insufficient parathyroid hormone production, as it may exacerbate calcium imbalances. Discuss all potential risks and benefits of treatment with your doctor to make an informed decision about your bone health management.

Uses of ODENSOMAB 60MG INJECTION

  • Osteoporosis
  • Bone loss due to hormonal therapy in breast or prostate cancer
  • Multiple myeloma (cancer affects plasma cells in the bone marrow)
  • Bone metastases (cancer that spreads to bone)

Side Effects of ODENSOMAB 60MG INJECTIONArrow

Like all medications, ODENSOMAB 60MG INJECTION can cause side effects, although not everyone who takes it will experience them. Serious side effects include osteonecrosis of the jaw (severe necrosis or death of jaw cells), atypical femoral fractures, and hypocalcemia (low blood calcium levels). Common side effects include injection site reactions, back pain, musculoskeletal pain, infections, abdominal pain, headache, and hypophosphatemia (low blood phosphate levels).

  • Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
  • Atypical femoral fractures
  • Hypocalcemia (low blood calcium levels)
  • Injection site reactions
  • Back pain
  • Musculoskeletal pain
  • Infections
  • Abdominal pain
  • Headache
  • Hypophosphatemia (low blood phosphate levels)

Safety Advice for ODENSOMAB 60MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

The safety of using ODENSOMAB 60MG INJECTION during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Dosage of ODENSOMAB 60MG INJECTIONArrow

  • ODENSOMAB 60MG INJECTION is administered via injection by qualified healthcare professionals, ensuring precise delivery and monitoring.
  • The specific dosage regimen, including the amount of medication and the frequency of administration, is carefully determined by your healthcare provider. This determination is based on a comprehensive evaluation of your individual medical condition, its severity, and your response to the treatment.
  • Adherence to the prescribed dosage and treatment duration is crucial for optimal therapeutic outcomes. Do not alter the dosage or discontinue treatment without consulting your healthcare provider. Any adjustments to the treatment plan should be made under their guidance to ensure safety and effectiveness.
  • Regular follow-up appointments with your healthcare provider are essential to monitor your progress and make any necessary adjustments to your treatment plan.

How to store ODENSOMAB 60MG INJECTION?Arrow

  • Keep ODENSOMAB 60MG INJ 1ML away from the reach of children and pets.
  • Store ODENSOMAB 60MG INJ 1ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ODENSOMAB 60MG INJECTIONArrow

  • ODENSOMAB 60MG INJECTION offers a range of therapeutic benefits centered around improving bone health and reducing fracture risk. Primarily, it functions by inhibiting bone resorption, a process where old bone tissue is broken down and removed, which can lead to weakened bones over time. The medication achieves this by targeting RANK ligands, key proteins that regulate osteoclasts, the cells responsible for bone resorption. By effectively blocking these ligands, ODENSOMAB 60MG INJECTION slows down bone breakdown.
  • A significant outcome of this action is the increase in bone mineral density (BMD). BMD is a crucial indicator of bone strength, and higher BMD values generally correlate with a lower risk of fractures. ODENSOMAB 60MG INJECTION helps to fortify the skeletal structure, making it more resistant to fractures, particularly in individuals diagnosed with osteoporosis or those identified as being at high risk of developing the condition. Regular use of the injection can lead to substantial improvements in BMD, providing a stronger foundation for the body.
  • The combined effects of reduced bone resorption and increased bone mineral density result in improved overall bone health. This translates to a decreased likelihood of fractures, which can significantly impact a patient's quality of life. By strengthening bones and preventing fractures, ODENSOMAB 60MG INJECTION helps individuals maintain their mobility, independence, and ability to perform daily activities without fear of injury. It is a proactive approach to managing bone health and mitigating the risks associated with osteoporosis and fragile bones.

How to use ODENSOMAB 60MG INJECTIONArrow

  • ODENSOMAB 60MG INJECTION is administered via injection by trained healthcare professionals. It is crucial that this medication is not self-administered. The precise dosage and the length of the treatment period will be determined by your healthcare provider, taking into account your specific medical condition, its severity, and your response to the treatment.
  • Your doctor will carefully evaluate your progress and adjust the treatment plan as needed. It is essential to adhere to the schedule of injections as prescribed by your doctor to achieve the best possible outcomes. Do not miss any scheduled appointments.
  • If you have any questions or concerns regarding the administration of ODENSOMAB 60MG INJECTION, please do not hesitate to discuss them with your healthcare provider. They are the best resource for addressing your concerns and ensuring you understand the treatment process fully.

FAQs

Can ODENSOMAB 60MG INJECTION be used in patients with a history of cancer?Arrow

ODENSOMAB 60MG INJECTION is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.

Can ODENSOMAB 60MG INJECTION be used in patients with kidney problems?Arrow

ODENSOMAB 60MG INJECTION is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.

Can ODENSOMAB 60MG INJECTION be used as a treatment for osteoporosis in men?Arrow

Yes, ODENSOMAB 60MG INJECTION is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.

Can ODENSOMAB 60MG INJECTION be used in children and adolescents with osteoporosis?Arrow

ODENSOMAB 60MG INJECTION is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.

Can ODENSOMAB 60MG INJECTION be used in individuals with dental implants?Arrow

ODENSOMAB 60MG INJECTION use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess ODENSOMAB 60MG INJECTION's potential risks and benefits.

What Are the Side Effects of ODENSOMAB 60MG INJECTION?Arrow

ODENSOMAB 60MG INJECTION can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.

Is there any interaction of ODENSOMAB 60MG INJECTION with other drugs?Arrow

There are no known significant negative interactions between ODENSOMAB 60MG INJECTION and other drugs. However, it is always important to inform your healthcare provider about all the medications, herbal supplements, and vitamins you are taking to avoid any potential risks.

What precautions should I take while taking ODENSOMAB 60MG INJECTION?Arrow

Attend all scheduled appointments and follow-up visits to monitor your response to treatment and address any concerns or side effects. Tell your doctor about your medical history, previous infection, liver disease, and kidney disease. Inform your healthcare provider about any allergies or hypersensitivity reactions you may have. Seek immediate medical attention if you experience severe allergic reactions or other serious side effects. Additionally, ODENSOMAB 60MG INJECTION may affect calcium levels, so monitoring calcium levels and ensuring adequate calcium and vitamin D intake is important. Pregnant and breastfeeding women should consult a doctor before taking this medication. Avoid taking any vaccines during treatment. Regular dental examinations and good oral hygiene practices are recommended to minimize the risk of jaw osteonecrosis.

What is ODENSOMAB 60MG INJECTION made of?Arrow

ODENSOMAB 60MG INJECTION is made from the molecule/combination called DENOSUMAB.

For which ailments/diseases/conditions is ODENSOMAB 60MG INJECTION prescribed?Arrow

ODENSOMAB 60MG INJECTION is prescribed for ailments/diseases/conditions related to Rheumatology and Orthopaedics.

References

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Amgen Ltd, Electronic medicines compendium (EMC)

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Amgen Manufacturing Limited, US Food and Drug Administration

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Amgen Manufacturing Limited, US Food and Drug Administration

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Reviewed on 20-01-2024

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Reviewed on 12-01-2024

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(5/5)


Marketer / Manufacturer Details

LUPIN LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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