GLICLAZ M TABLET 15'S

How GLICLAZ M TABLET 15'S Works

• GLICLAZ M TABLET 15'S is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients: Gliclazide and Metformin. Each component works through different mechanisms to lower blood glucose levels and improve overall glycemic control.
• Gliclazide belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into cells, where it can be used for energy. By increasing insulin secretion, Gliclazide helps lower blood sugar levels, particularly after meals. This action is glucose-dependent, meaning it's more effective when blood sugar levels are high, reducing the risk of hypoglycemia (low blood sugar) compared to older sulfonylureas.
• Metformin, on the other hand, is a biguanide. It works through several mechanisms. Firstly, it decreases glucose production in the liver by suppressing hepatic gluconeogenesis. The liver is a major source of glucose in the body, and Metformin reduces the amount of glucose it releases into the bloodstream. Secondly, Metformin enhances insulin sensitivity in peripheral tissues such as muscles. This means that cells become more responsive to insulin, allowing them to take up glucose more effectively. Thirdly, Metformin slows down the absorption of glucose from the intestines into the bloodstream after a meal. This helps to prevent sharp spikes in blood sugar levels after eating.
• When combined, Gliclazide and Metformin offer a complementary approach to managing blood sugar. Gliclazide boosts insulin secretion, while Metformin reduces glucose production, improves insulin sensitivity, and slows glucose absorption. This dual action helps to achieve better blood sugar control than either drug could achieve alone.
• The overall effect of GLICLAZ M TABLET 15'S is to lower both fasting and postprandial (after-meal) blood sugar levels, improving HbA1c levels (a measure of long-term blood sugar control). By maintaining stable blood sugar levels, GLICLAZ M TABLET 15'S helps to reduce the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular disease.
• It is important to take GLICLAZ M TABLET 15'S as directed by your healthcare provider and to follow a healthy diet and exercise plan to maximize its effectiveness. Regular monitoring of blood sugar levels is also crucial to ensure that the medication is working properly and to adjust the dosage if needed.

Like all medicines, GLICLAZ M TABLET 15'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar): Symptoms may include sweating, paleness, tremor, anxiety, unusual tiredness or weakness, confusion, difficulty concentrating, rapid heartbeat, excessive hunger, temporary visual disturbances, speech difficulties. * Gastrointestinal disturbances: Abdominal pain, nausea, vomiting, indigestion, diarrhea, constipation. These can be minimized if GLICLAZ M TABLET 15'S is taken with food. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Visual impairment: Especially at the start of treatment, due to changes in blood sugar levels. This effect is usually temporary. * Elevated liver enzymes: Detected in blood tests, indicating possible liver problems. **Rare Side Effects (may affect up to 1 in 1,000 people):** * Blood disorders: Decrease in the number of blood cells (e.g., platelets, white blood cells, red blood cells), which can cause paleness, prolonged bleeding, bruising, sore throat, fever. * Skin reactions: Rash, itching, hives, angioedema (swelling of the face, lips, tongue, or throat which may cause difficulty breathing or swallowing). **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Liver problems: Hepatitis (inflammation of the liver), jaundice (yellowing of the skin and eyes), liver failure. In isolated cases, severe liver problems can occur. **Other Possible Side Effects:** * Headache * Dizziness * General feeling of being unwell **Important:** * If you experience symptoms of hypoglycemia, take a sugary snack or drink immediately and consult your doctor. * If you experience any of the following, stop taking GLICLAZ M TABLET 15'S and seek immediate medical attention: * Severe allergic reaction (angioedema) * Signs of liver problems (jaundice, dark urine, pale stools, abdominal pain) * Unexplained bleeding or bruising * Signs of a blood disorder (sore throat, fever, paleness) This is not a complete list of side effects. If you experience any other unusual symptoms, talk to your doctor or pharmacist.

• If you miss a dose of GLICLAZ M TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep GLICLAZ M TAB 1X15 away from the reach of children and pets.
• Store GLICLAZ M TAB 1X15 at room temperature.

• Take Gliclazide and Metformin combination (GLICLAZ M TABLET 15'S) strictly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This medication is typically taken orally, once or twice daily, with meals to minimize gastrointestinal side effects and maximize its effectiveness in controlling blood sugar levels.
• Follow a balanced diet and exercise regularly while taking Gliclazide and Metformin. This medication works best when combined with lifestyle changes such as a healthy diet low in sugars and refined carbohydrates, and regular physical activity. These habits can significantly improve blood sugar control and overall health.
• Monitor your blood sugar levels regularly, especially when starting Gliclazide and Metformin (GLICLAZ M TABLET 15'S). Regular monitoring helps you understand how your body responds to the medication and allows for timely adjustments in dosage or treatment plan by your healthcare provider. Keep a record of your blood sugar readings and share them with your doctor.
• Be aware of the symptoms of low blood sugar (hypoglycemia) while on Gliclazide and Metformin. Symptoms can include shakiness, sweating, confusion, dizziness, rapid heartbeat, and hunger. Always carry a source of fast-acting sugar, such as glucose tablets or fruit juice, to treat hypoglycemia promptly. Inform your family and friends about the symptoms and how to assist you in case of an emergency.
• Inform your doctor about all other medications, supplements, and medical conditions you have before starting Gliclazide and Metformin (GLICLAZ M TABLET 15'S). This medication can interact with other drugs, affecting its efficacy or increasing the risk of side effects. Conditions like kidney or liver problems may also necessitate dosage adjustments or alternative treatments. Full disclosure ensures your safety and the effectiveness of your treatment.

• It is advisable to take GLICLAZ M TABLET 15'S with food to avoid stomach upset and to maintain consistent blood sugar levels. Avoid skipping meals while taking this medication.