ISTAMET D XR 1000MG TABLET 7'S

How ISTAMET D XR 1000MG TABLET 7'S Works

• ISTAMET D XR 1000MG TABLET 7'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: metformin and a dipeptidyl peptidase-4 (DPP-4) inhibitor. Each component works through different mechanisms to achieve better glycemic control.
• Metformin, the primary ingredient, primarily works by decreasing glucose production in the liver. It reduces hepatic gluconeogenesis, which is the process by which the liver converts non-carbohydrate sources into glucose. By inhibiting this process, metformin lowers the amount of glucose released into the bloodstream, particularly during fasting periods and overnight. Metformin also enhances insulin sensitivity in peripheral tissues, such as muscles and fat. This means that cells become more responsive to insulin, allowing them to uptake glucose more efficiently from the blood. This improved insulin sensitivity further contributes to lower blood sugar levels, especially after meals. Additionally, Metformin slows down the absorption of glucose from the intestines into the bloodstream, reducing the postprandial (after-meal) glucose spike. This helps in maintaining stable blood sugar levels throughout the day. The 'XR' in ISTAMET D XR stands for extended-release, meaning that the medication is released slowly into the body over a longer period, providing a more consistent effect and reducing the frequency of dosage.
• The DPP-4 inhibitor component in ISTAMET D XR works by increasing the levels of incretin hormones in the body. Incretins, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released from the intestines in response to food intake. These hormones stimulate insulin release from the pancreas in a glucose-dependent manner, meaning that insulin is released only when blood sugar levels are high. They also suppress glucagon secretion, a hormone that raises blood sugar levels. By inhibiting DPP-4, the enzyme that breaks down incretin hormones, ISTAMET D XR prolongs the action of GLP-1 and GIP. This leads to increased insulin secretion, decreased glucagon secretion, and ultimately, better blood sugar control, particularly after meals. The combined effect of metformin reducing glucose production and improving insulin sensitivity, along with the DPP-4 inhibitor enhancing incretin activity, results in a synergistic action that effectively lowers blood sugar levels in individuals with type 2 diabetes. Regular monitoring of blood sugar levels and adherence to a healthy diet and exercise plan are crucial for optimizing the benefits of ISTAMET D XR 1000MG TABLET 7'S.

The following side effects may occur while using ISTAMET D XR 1000MG TABLET 7'S. It is important to consult your doctor if you experience any of these or other concerning symptoms: **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Headache * Weakness **Uncommon Side Effects:** * Hypoglycemia (low blood sugar) * Skin rash or itching * Dizziness * Constipation * Gas * Heartburn **Rare and Serious Side Effects (Seek immediate medical attention):** * Lactic acidosis (symptoms may include feeling very weak, tired or uncomfortable; unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat) * Vitamin B12 deficiency * Liver problems (symptoms may include persistent nausea/vomiting, severe abdominal pain, yellowing eyes/skin, dark urine) * Pancreatitis (severe stomach pain radiating to the back, with nausea and vomiting) * Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)

• If you miss a dose of ISTAMET D XR 1000MG TABLET 7'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep ISTAMET D XR 1000MG TAB 1X7 away from the reach of children and pets.
• Store ISTAMET D XR 1000MG TAB 1X7 at room temperature.

• Take ISTAMET D XR 1000MG TABLET 7'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a glass of water. Usually, it is taken once daily with the evening meal to minimize stomach upset.
• ISTAMET D XR 1000MG TABLET 7'S helps control high blood sugar. Continue to follow your diet and exercise program as directed by your doctor. Regular physical activity and a balanced diet are crucial for managing your diabetes effectively alongside this medication.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. Keep a record of your readings and share them with your doctor during your appointments. This will help them assess how well the medication is working and adjust your treatment plan if needed.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, rapid heartbeat, and confusion. Carry a source of fast-acting sugar with you, such as glucose tablets or fruit juice, to treat hypoglycemia promptly. Inform your family and friends about recognizing and managing hypoglycemia.
• Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with ISTAMET D XR 1000MG TABLET 7'S. Pay special attention to medications that can affect blood sugar levels, such as corticosteroids or diuretics. Also, notify your doctor if you have any kidney or liver problems before starting this medication.

• ISTAMET D XR 1000MG TABLET 7'S should be taken with food to decrease the chance of an upset stomach.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.
• Follow your doctor's dietary recommendations carefully while taking this medication to manage your blood sugar levels effectively.