JAKNAT 5MG TABLET 10'S
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JAKNAT 5MG TABLET 10'SJAKNAT 5MG TABLET 10'S
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JAKNAT 5MG TABLET 10'S

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JAKNAT 5MG TABLET 10'S

By NATCO PHARMA LIMITED

MRP

370

₹314.5

15 % OFF

₹31.45 Only /

Tablet

58

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Composition

Product DetailsArrow

About JAKNAT 5MG TABLET 10'S

  • JAKNAT 5MG TABLET 10'S contains the active substance Tofacitinib. It is a disease-modifying anti-rheumatoid drug (DMARDs) that belongs to the class of immunomodulators. This medication is used, either alone or in conjunction with other medications, to treat rheumatoid arthritis—a condition where the body mistakenly attacks its joints, leading to pain, swelling, and impaired function—in adults who haven't responded well to or are unable to take other treatments. It's also prescribed for psoriatic arthritis, a condition characterized by joint pain and swelling, accompanied by scales on the skin. Furthermore, it's indicated for treating adult patients with moderately to severely active ulcerative colitis.
  • JAKNAT 5MG TABLET 10'S also has other applications, including the treatment of ankylosing spondylitis, an inflammatory disease affecting the spine. Additionally, it is used to manage active polyarticular juvenile idiopathic arthritis, a chronic condition primarily causing pain and swelling in the joints of patients aged two years and older. This medicine functions by reducing the activity of the immune system. It is crucial to inform your physician if you have a severe blood infection, active tuberculosis, or liver problems. It's also important to notify your doctor if you have a history of or currently have a hepatitis B infection, as this medication may reactivate the virus.
  • Do not take JAKNAT 5MG TABLET 10'S if you are allergic to tofacitinib or any of its other ingredients. Inform your healthcare provider about any symptoms of infection you may be experiencing, such as fever, sweating, chills, muscle aches, cough, shortness of breath, weight loss, skin sores, difficulty or pain when swallowing, diarrhea, or stomach pain. Before starting treatment with this medication, disclose to your physician if you have any kidney, heart, lung, or liver issues, a history of tuberculosis, high blood pressure, high cholesterol, or if you are a current or former smoker. This comprehensive medical history helps ensure the safe and effective use of JAKNAT 5MG TABLET 10'S.
  • This medication works by selectively inhibiting Janus kinases (JAKs), enzymes that play a crucial role in the signaling pathways of various cytokines involved in immune and inflammatory responses. By blocking these enzymes, JAKNAT 5MG TABLET 10'S helps to reduce the overactivity of the immune system that leads to inflammation and joint damage in conditions like rheumatoid arthritis and psoriatic arthritis. Regular monitoring by your doctor is important to assess the effectiveness of the treatment and to watch for any potential side effects. Adhering to the prescribed dosage and schedule is also essential for achieving the best possible outcomes from your treatment.

Uses of JAKNAT 5MG TABLET 10'S

  • Rheumatoid arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet.
  • Psoriatic arthritis: A type of arthritis that affects people with psoriasis, causing joint pain and stiffness.
  • Ankylosing spondylitis: An inflammatory disease that, over time, can cause some of the vertebrae in your spine to fuse.
  • Ulcerative colitis: An inflammatory bowel disease (IBD) that causes inflammation and ulcers in your digestive tract.
  • Polyarticular juvenile idiopathic arthritis: A type of arthritis that affects multiple joints in children.
  • Juvenile psoriatic arthritis: A type of arthritis associated with psoriasis that occurs in children.

Side Effects of JAKNAT 5MG TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. JAKNAT 5MG TABLET 10'S can cause both common and serious side effects.

  • Increased cholesterol levels
  • Headache
  • Painful urination
  • Inflammation of the nose
  • Cough
  • Shortness of breath
  • Diarrhea
  • Skin rashes
  • Lung cancer
  • White blood cell cancer
  • Heart attack
  • Fever and chills
  • Blood in the stool
  • Stomach pain or abdominal pain
  • Skin blisters

Safety Advice for JAKNAT 5MG TABLET 10'SArrow

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Pregnancy

UNSAFE

JAKNAT 5MG TABLET 10'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 4 weeks after your last dose is necessary.

Dosage of JAKNAT 5MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with JAKNAT 5MG TABLET 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medication.
  • Swallow the tablet whole with a glass of water. Avoid breaking, crushing, or chewing the tablets, as this could affect how the medication is absorbed and works in your body. You can take JAKNAT 5MG TABLET 10'S with or without food, but consistency in when you take it each day can be helpful.
  • Missing doses can reduce the medicine's effectiveness, so try to take JAKNAT 5MG TABLET 10'S at the same time every day to maintain a consistent level of medication in your system. If you have any questions or concerns about how to take JAKNAT 5MG TABLET 10'S, consult with your doctor or pharmacist for clarification.

How to store JAKNAT 5MG TABLET 10'S?Arrow

  • Keep JAKNAT 5MG TAB 1X10 away from the reach of children and pets.
  • Store JAKNAT 5MG TAB 1X10 at room temperature.

Benefits of JAKNAT 5MG TABLET 10'SArrow

  • JAKNAT 5MG TABLET 10'S is classified as a disease-modifying anti-rheumatic drug (DMARD) and belongs to the class of Janus Kinase Inhibitors. These inhibitors target Janus kinases, which are enzymes (specifically, tyrosine kinases) crucial for cytokine receptor signaling pathways. Cytokines play a vital role in immune responses and inflammation, and their signals are transmitted through the Janus kinase-STAT pathway. By selectively inhibiting Janus kinases, JAKNAT 5MG TABLET 10'S disrupts this signaling cascade.
  • This interference impacts the transcription of genes responsible for cell growth, differentiation, and immune function. In simpler terms, it helps to regulate the overactive immune system that is characteristic of certain autoimmune diseases. This action ultimately reduces inflammation and alleviates the symptoms associated with these conditions.
  • By modulating the activity of Janus kinases, JAKNAT 5MG TABLET 10'S helps to restore balance to the immune system and reduce the damaging effects of chronic inflammation. This can lead to significant improvements in joint pain, swelling, and overall function for individuals suffering from rheumatoid arthritis and other related conditions.

How to use JAKNAT 5MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere to your doctor's prescribed instructions for taking JAKNAT 5MG TABLET 10'S.
  • To ensure optimal absorption and effectiveness, swallow the tablet whole with a full glass of water. Avoid breaking, crushing, or chewing the tablet, as this may alter its intended release mechanism and potentially affect its efficacy.
  • JAKNAT 5MG TABLET 10'S can be taken either with or without food. If you have a sensitive stomach, taking it with a meal might help to minimize any potential gastrointestinal discomfort. However, consistency is key, so try to take it around the same time each day to maintain a stable level of the medication in your system.
  • If you have any questions or concerns regarding the proper way to take JAKNAT 5MG TABLET 10'S, please do not hesitate to consult your doctor or pharmacist. They can provide personalized guidance based on your individual needs and medical history. Never adjust the dosage or frequency of administration without first consulting with your healthcare provider.

FAQs

What are the cautions of JAKNAT 5MG TABLET 10'S?Arrow

Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing. JAKNAT 5MG TABLET 10'S can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.

Does JAKNAT 5MG TABLET 10'S cause high cholesterol?Arrow

Increased cholesterol levels are one of the side effects of JAKNAT 5MG TABLET 10'S, your doctor may take regular blood tests to check for serious side effects.

Can JAKNAT 5MG TABLET 10'S cause depression?Arrow

No, JAKNAT 5MG TABLET 10'S does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.

Does JAKNAT 5MG TABLET 10'S cause blood clots?Arrow

Yes, blood clots are reported in patients using JAKNAT 5MG TABLET 10'S for a longer period. Inform your physician if you face any symptoms of a blood clot.

How long does it take JAKNAT 5MG TABLET 10'S to work?Arrow

JAKNAT 5MG TABLET 10'S is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.

What are the drug interactions of JAKNAT 5MG TABLET 10'S?Arrow

There is no known interaction of JAKNAT 5MG TABLET 10'S with other drugs.

What advice should I follow while taking JAKNAT 5MG TABLET 10'S?Arrow

This medicine may interfere with vaccines, inform your physician about your vaccination history. This medicine may impair fertility; talk to your doctor before taking this medicine. Your doctor will regularly do lab tests to check whether the medicine is working. Do not breastfeed during the treatment with this medicine and for at least 36 hours after your last dose. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

What molecule/combination is used for making JAKNAT 5MG TABLET 10'S?Arrow

TOFACITINIB is molecule/combination used for making JAKNAT 5MG TABLET 10'S.

For what ailments/diseases/conditions is JAKNAT 5MG TABLET 10'S prescribed?Arrow

JAKNAT 5MG TABLET 10'S is prescribed for ailments/diseases/conditions related to Rheumatology.

Does JAKNAT 5MG TABLET 10'S help with bone problems?Arrow

JAKNAT 5MG TABLET 10'S is prescribed for ailments/diseases/conditions related to Orthopaedics.

References

Book Icon

XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk.

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HIGHLIGHTS OF PRESCRIBING INFORMATION - Tofacitinib.

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS - Tofacitinib.

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Ratings & Review

Very cheap, helpful, friendly service

Milind Patel

Reviewed on 10-02-2023

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(5/5)

Amazing service and customer friendly

Deepak Patel

Reviewed on 05-11-2022

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(3/5)

Good series, satisfied customer

Sameer Jadhav

Reviewed on 06-01-2024

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(5/5)

Great experience wonderful experience nice palce for low cost medicine

vast chance

Reviewed on 10-06-2023

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(5/5)

Interactive and knowledgeable

Naval Kava

Reviewed on 01-04-2024

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(5/5)


Marketer / Manufacturer Details

NATCO PHARMA LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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