TOFAMARK TABLET 10'S
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TOFAMARK TABLET 10'S
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TOFAMARK TABLET 10'S

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TOFAMARK TABLET 10'S

By APRAZER HEALTHCARE PVT LTD

MRP

346.88

₹312.19

10 % OFF

₹31.22 Only /

Tablet

10

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About TOFAMARK TABLET 10'S

  • TOFAMARK TABLET 10'S contains the active substance Tofacitinib, a disease-modifying anti-rheumatoid drug (DMARD) belonging to the immunomodulator class. It's prescribed, either alone or with other medications, to treat rheumatoid arthritis—a condition where the body mistakenly attacks its joints, leading to pain, swelling, and impaired function—in adults who haven't responded well to other treatments. It's also effective for psoriatic arthritis, which causes joint pain, swelling, and skin scaling. Additionally, TOFAMARK TABLET 10'S is used to treat adult patients with moderately to severely active ulcerative colitis.
  • Beyond these primary uses, TOFAMARK TABLET 10'S can also be prescribed for ankylosing spondylitis, an inflammatory disease affecting the spine. Furthermore, it treats active polyarticular juvenile idiopathic arthritis—a long-term condition causing joint pain and swelling, primarily in patients aged two years and older. The medication works by reducing the activity of the immune system, thus alleviating inflammation and its associated symptoms. Before starting TOFAMARK TABLET 10'S, it’s vital to inform your doctor if you have a severe blood infection, active tuberculosis, or liver problems. Also, disclose any history of hepatitis B infection, as this medication can reactivate the virus.
  • You should not take TOFAMARK TABLET 10'S if you are allergic to tofacitinib or any of its other ingredients. It is essential to inform your healthcare provider about any infection symptoms you may have, such as fever, sweating, chills, muscle aches, cough, shortness of breath, unexplained weight loss, skin sores, difficulty or pain when swallowing, diarrhea, or stomach pain. Prior to starting treatment, tell your doctor if you have any kidney, heart, lung, or liver issues, a history of tuberculosis, high blood pressure, or high cholesterol. Also, inform them if you are a current or former smoker, as smoking can affect the drug's efficacy and increase the risk of side effects. Regular monitoring by your healthcare provider is crucial during treatment to ensure safety and effectiveness.

Uses of TOFAMARK TABLET 10'S

  • Rheumatoid arthritis: This is an autoimmune disease that causes inflammation and pain in the joints. TOFAMARK TABLET 10'S can help reduce this inflammation and manage symptoms.
  • Psoriatic arthritis: This is a type of arthritis that affects people with psoriasis, a skin condition. TOFAMARK TABLET 10'S helps alleviate joint pain and inflammation associated with psoriatic arthritis.
  • Ankylosing spondylitis: This is an inflammatory disease that primarily affects the spine, causing stiffness and pain. TOFAMARK TABLET 10'S can help manage symptoms and improve flexibility.
  • Ulcerative colitis: This is an inflammatory bowel disease (IBD) that affects the large intestine. TOFAMARK TABLET 10'S helps reduce inflammation in the colon and alleviate symptoms.
  • Polyarticular juvenile idiopathic arthritis: A type of arthritis that occurs in children, affecting multiple joints. TOFAMARK TABLET 10'S helps manage pain and inflammation.
  • Juvenile psoriatic arthritis: A type of arthritis that occurs in children and is associated with psoriasis. TOFAMARK TABLET 10'S helps control joint pain, swelling, and skin symptoms.

Side Effects of TOFAMARK TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. TOFAMARK TABLET 10'S can cause both common and serious side effects.

  • Increased cholesterol levels
  • Headache
  • Painful urination
  • Inflammation of the nose
  • Cough
  • Shortness of breath
  • Diarrhea
  • Skin rashes
  • Lung cancer
  • White blood cell cancer
  • Heart attack
  • Fever and chills
  • Blood in the stool
  • Stomach pain or abdominal pain
  • Skin blisters

Safety Advice for TOFAMARK TABLET 10'SArrow

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Pregnancy

UNSAFE

TOFAMARK TABLET 10'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 4 weeks after your last dose is necessary.

Dosage of TOFAMARK TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's prescribed instructions regarding the use of TOFAMARK TABLET 10'S. This ensures the medication works effectively and minimizes potential risks.
  • Administer TOFAMARK TABLET 10'S exactly as directed by your healthcare provider. Do not alter the dosage or frequency of administration without consulting your doctor. Such changes can impact the drug's effectiveness and may lead to unwanted side effects. Consistency is key to successful treatment.
  • The tablets should be swallowed whole with a full glass of water. Avoid breaking, crushing, or chewing the tablets, as this can affect how the medication is absorbed into your system. You can take TOFAMARK TABLET 10'S with or without food, but maintaining a consistent approach can help ensure optimal results. If you experience any stomach upset, taking it with food may be beneficial.

How to store TOFAMARK TABLET 10'S?Arrow

  • Keep TOFAMARK 5MG TAB 1X10 away from the reach of children and pets.
  • Store TOFAMARK 5MG TAB 1X10 at room temperature.

Benefits of TOFAMARK TABLET 10'SArrow

  • TOFAMARK TABLET 10'S is classified as a disease-modifying anti-rheumatic drug (DMARD), specifically a Janus Kinase (JAK) inhibitor. This means it helps to slow down the progression of rheumatic diseases by targeting specific pathways within the immune system.
  • Janus kinases are enzymes crucial for cytokine receptor signaling. Cytokines are proteins that play a vital role in cell communication, especially in immune responses. By inhibiting Janus kinases, TOFAMARK TABLET 10'S interferes with this signaling process.
  • The inhibition of Janus kinases affects the transcription of genes involved in cell growth and differentiation. This helps to modulate the overactive immune response seen in rheumatic diseases, reducing inflammation and joint damage.
  • TOFAMARK TABLET 10'S offers a targeted approach to managing rheumatic conditions, providing relief from symptoms and potentially slowing down the long-term progression of the disease. It is important to take this medication exactly as prescribed by your doctor.
  • This medication's mechanism of action distinguishes it from other treatments, providing an alternative for individuals who may not have responded well to other therapies. Consulting with a healthcare professional is essential for determining if TOFAMARK TABLET 10'S is the right choice for your specific condition.

How to use TOFAMARK TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TOFAMARK TABLET 10'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's instructions regarding the dosage and timing of the medication.
  • Administer TOFAMARK TABLET 10'S orally, exactly as prescribed by your healthcare provider. To ensure proper absorption and effectiveness, do not break, crush, or chew the tablets. Instead, swallow the tablet whole with a full glass of water.
  • You can take TOFAMARK TABLET 10'S either with or without food, as directed by your doctor. Maintaining a consistent schedule for taking the medication each day can help optimize its therapeutic effects and minimize the likelihood of missed doses.
  • If you have any concerns about how to take TOFAMARK TABLET 10'S, or if you experience any unusual side effects, consult with your doctor or pharmacist for further guidance.

FAQs

What are the cautions of TOFAMARK TABLET 10'S?Arrow

Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing. TOFAMARK TABLET 10'S can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.

Does TOFAMARK TABLET 10'S cause high cholesterol?Arrow

Increased cholesterol levels are one of the side effects of TOFAMARK TABLET 10'S, your doctor may take regular blood tests to check for serious side effects.

Can TOFAMARK TABLET 10'S cause depression?Arrow

No, TOFAMARK TABLET 10'S does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.

Does TOFAMARK TABLET 10'S cause blood clots?Arrow

Yes, blood clots are reported in patients using TOFAMARK TABLET 10'S for a longer period. Inform your physician if you face any symptoms of a blood clot.

How long does it take TOFAMARK TABLET 10'S to work?Arrow

TOFAMARK TABLET 10'S is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.

Does TOFAMARK TABLET 10'S interact with other drugs?Arrow

There is no known interaction of TOFAMARK TABLET 10'S with other drugs.

What advice should I follow while taking TOFAMARK TABLET 10'S?Arrow

This medicine may interfere with vaccines, inform your physician about your vaccination history. This medicine may impair fertility; talk to your doctor before taking this medicine. Your doctor will regularly do lab tests to check whether the medicine is working. Do not breastfeed during the treatment with this medicine and for at least 36 hours after your last dose. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

What is TOFAMARK TABLET 10'S made of?Arrow

TOFACITINIB is molecule/combination used for making TOFAMARK TABLET 10'S.

For which ailments/diseases/conditions is TOFAMARK TABLET 10'S prescribed?Arrow

TOFAMARK TABLET 10'S is prescribed for Rheumatology and Orthopaedics related ailments.

References

Book Icon

XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk.

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HIGHLIGHTS OF PRESCRIBING INFORMATION - Tofacitinib.

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS - Tofacitinib.

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Reviewed on 18-01-2024

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(5/5)


Marketer / Manufacturer Details

APRAZER HEALTHCARE PVT LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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