TOFE 5MG TABLET 10'S
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TOFE 5MG TABLET 10'STOFE 5MG TABLET 10'STOFE 5MG TABLET 10'S
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TOFE 5MG TABLET 10'S

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TOFE 5MG TABLET 10'S

By ALKEM LABORATORIES LIMITED

MRP

195.94

₹166.55

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Product DetailsArrow

Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About TOFE 5MG TABLET 10'S

  • TOFE 5MG TABLET 10'S contains tofacitinib, a disease-modifying anti-rheumatic drug (DMARD) and immunomodulator. It is prescribed, either alone or with other medications, for adults with rheumatoid arthritis who haven't responded well to other treatments. Rheumatoid arthritis is a condition where the body's immune system mistakenly attacks the joints, leading to pain, swelling, and impaired function. It is also effective in treating psoriatic arthritis, characterized by joint pain, swelling, and skin scales, as well as moderately to severely active ulcerative colitis in adults.
  • Beyond these primary uses, TOFE 5MG TABLET 10'S can also be used to manage ankylosing spondylitis, an inflammatory spine condition. Additionally, it's indicated for active polyarticular juvenile idiopathic arthritis in patients aged two years and older, addressing joint pain and swelling associated with this long-term condition. The medication functions by reducing the activity of the immune system. It's crucial to inform your doctor if you have a severe blood infection, active tuberculosis, or liver problems. Also, disclose any past or present hepatitis B infection, as TOFE 5MG TABLET 10'S might reactivate the virus.
  • Avoid TOFE 5MG TABLET 10'S if you're allergic to tofacitinib or any of its other ingredients. Before starting treatment, tell your healthcare provider about any signs of infection like fever, sweating, chills, muscle aches, cough, shortness of breath, weight loss, skin sores, difficulty swallowing, diarrhea, or stomach pain. It's also important to discuss any existing kidney, heart, lung, or liver issues, a history of tuberculosis, high blood pressure, high cholesterol, or smoking habits (past or present) with your physician.

Uses of TOFE 5MG TABLET 10'S

  • Rheumatoid arthritis is an autoimmune and inflammatory disease in which your immune system attacks healthy cells in your own body, causing painful swelling in the affected parts of the body. This can result in bone erosion and joint deformity if not treated properly.
  • Psoriatic arthritis is a type of arthritis that affects people who have psoriasis, a condition that causes red, scaly patches on the skin. Psoriatic arthritis can cause joint pain, stiffness, and swelling.
  • Ankylosing spondylitis is an inflammatory disease that, over time, can cause some of the vertebrae in your spine to fuse. This fusing makes the spine less flexible and can result in a hunched posture. It causes pain and stiffness.
  • Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in your digestive tract. Ulcerative colitis affects the innermost lining of your large intestine (colon) and rectum.
  • Polyarticular juvenile idiopathic arthritis is a type of arthritis that affects many joints. 'Poly' means many. It is an autoimmune condition where the body's immune system attacks its own cells and tissues.
  • Juvenile psoriatic arthritis is a type of arthritis that affects children who have psoriasis, a skin condition that causes red, scaly rashes. It can cause joint pain, swelling, and stiffness.

Side Effects of TOFE 5MG TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. **Common Side Effects:** Increased cholesterol levels, Headache, Painful urination, Inflammation of the nose, Cough, Shortness of breath, Diarrhea, Skin rashes. **Serious Side Effects:** Lung cancer, White blood cell cancer, Heart attack, Fever and chills, Blood in the stool, Stomach pain or abdominal pain, Skin blisters.

  • Increased cholesterol levels
  • Headache
  • Painful urination
  • Inflammation of the nose
  • Cough
  • Shortness of breath
  • Diarrhea
  • Skin rashes
  • Lung cancer
  • White blood cell cancer
  • Heart attack
  • Fever and chills
  • Blood in the stool
  • Stomach pain or abdominal pain
  • Skin blisters

Safety Advice for TOFE 5MG TABLET 10'SArrow

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Pregnancy

UNSAFE

TOFE 5MG TABLET 10'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 4 weeks after your last dose is necessary.

Dosage of TOFE 5MG TABLET 10'SArrow

  • The dosage and duration of your treatment with TOFE 5MG TABLET 10'S will be determined by your doctor, taking into account your specific medical condition, its severity, and other relevant factors. It is crucial to adhere to your doctor's prescribed dosage and schedule for optimal results.
  • Administer TOFE 5MG TABLET 10'S exactly as directed by your healthcare provider. Avoid altering the dosage or frequency without consulting them first. Consistency in taking the medication is important for its effectiveness.
  • These tablets should be swallowed whole with a glass of water. To ensure the medication is properly absorbed, do not break, crush, or chew the tablets. Whether you take TOFE 5MG TABLET 10'S with or without food is generally acceptable, but follow your doctor's specific instructions.
  • If you have any concerns about how to take TOFE 5MG TABLET 10'S or experience any adverse effects, consult your doctor or pharmacist for clarification and guidance. Proper administration and adherence to the prescribed regimen are essential for achieving the desired therapeutic outcomes.

How to store TOFE 5MG TABLET 10'S?Arrow

  • Keep TOFE 5MG TAB 1X10 away from the reach of children and pets.
  • Store TOFE 5MG TAB 1X10 at room temperature.

Benefits of TOFE 5MG TABLET 10'SArrow

  • TOFE 5MG TABLET 10'S is a disease-modifying anti-rheumatic drug (DMARD) that helps to slow down the progression of rheumatoid arthritis and other autoimmune conditions. It belongs to a class of medications known as Janus Kinase (JAK) inhibitors. These inhibitors work by targeting specific enzymes inside your cells called Janus kinases. These enzymes are crucial for the signaling pathways that control inflammation and immune responses.
  • By inhibiting these Janus kinases, TOFE 5MG TABLET 10'S effectively reduces the overactivity of the immune system that is characteristic of autoimmune diseases. This helps to alleviate symptoms such as joint pain, swelling, and stiffness, and can also prevent further damage to the joints and other organs. The medication interferes with the transcription of genes involved in cell growth and differentiation, further modulating the immune response.
  • TOFE 5MG TABLET 10'S can significantly improve the quality of life for individuals suffering from rheumatoid arthritis and similar conditions by providing relief from pain and inflammation, improving joint function, and slowing down the progression of the disease.

How to use TOFE 5MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant individual factors. It is crucial to adhere strictly to your doctor's prescribed instructions for taking TOFE 5MG TABLET 10'S. These tablets are designed to be swallowed whole and should not be broken, crushed, or chewed, as this could affect how the medication is absorbed and works in your body.
  • Always swallow TOFE 5MG TABLET 10'S with a full glass of water to aid in swallowing and ensure proper absorption. You can take TOFE 5MG TABLET 10'S either with food or on an empty stomach, as directed by your healthcare provider. Maintaining a consistent routine for taking your medication can help you remember to take it regularly and maximize its effectiveness.
  • If you have any questions or concerns about how to take TOFE 5MG TABLET 10'S, or if you experience any unexpected side effects, consult your doctor or pharmacist for further guidance. Never adjust your dosage or stop taking the medication without first consulting your doctor, as this could have adverse consequences for your health.

FAQs

What are the cautions of TOFE 5MG TABLET 10'S?Arrow

Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing. TOFE 5MG TABLET 10'S can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.

Does TOFE 5MG TABLET 10'S cause high cholesterol?Arrow

Increased cholesterol levels are one of the side effects of TOFE 5MG TABLET 10'S, your doctor may take regular blood tests to check for serious side effects.

Can TOFE 5MG TABLET 10'S cause depression?Arrow

No, TOFE 5MG TABLET 10'S does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.

Does TOFE 5MG TABLET 10'S cause blood clots?Arrow

Yes, blood clots are reported in patients using TOFE 5MG TABLET 10'S for a longer period. Inform your physician if you face any symptoms of a blood clot.

How long does it take TOFE 5MG TABLET 10'S to work?Arrow

TOFE 5MG TABLET 10'S is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.

What are the interactions of TOFE 5MG TABLET 10'S with other drugs?Arrow

There is no known interaction of TOFE 5MG TABLET 10'S with other drugs.

What is the advice related to TOFE 5MG TABLET 10'S?Arrow

This medicine may interfere with vaccines, inform your physician about all your vaccination history. This medicine may impair fertility; talk to your doctor before taking this medicine. Your doctor will regularly do lab tests to check whether the medicine is working. Do not breastfeed during the treatment with this medicine and for at least 36 hours after your last dose. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

Which molecule/combination is used for making TOFE 5MG TABLET 10'S?Arrow

TOFACITINIB is the molecule/combination used for making TOFE 5MG TABLET 10'S.

For which ailments/diseases/conditions is TOFE 5MG TABLET 10'S prescribed?Arrow

TOFE 5MG TABLET 10'S is prescribed for Rheumatology related ailments/diseases/conditions.

Does TOFE 5MG TABLET 10'S help with Orthopedic problems?Arrow

TOFE 5MG TABLET 10'S is prescribed for Orthopaedics related ailments/diseases/conditions.

References

Book Icon

XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk.

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HIGHLIGHTS OF PRESCRIBING INFORMATION - Tofacitinib.

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Annex I summary of product characteristics - Tofacitinib.

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Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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