LINERO D 10/5MG TABLET 10'S
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LINERO D 10/5MG TABLET 10'SLINERO D 10/5MG TABLET 10'SLINERO D 10/5MG TABLET 10'S
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LINERO D 10/5MG TABLET 10'S

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LINERO D 10/5MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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169.9

₹144.42

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About LINERO D 10/5MG TABLET 10'S

  • LINERO D 10/5MG TABLET 10'S is a combination medication designed to manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients: Linagliptin and Dapagliflozin. Linagliptin belongs to a class of drugs called DPP-4 inhibitors, while Dapagliflozin is an SGLT2 inhibitor.
  • Linagliptin works by increasing the amount of incretin hormones in the body. These hormones stimulate the release of insulin after a meal and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By enhancing incretin activity, Linagliptin helps to improve blood sugar control.
  • Dapagliflozin, on the other hand, works by blocking the reabsorption of glucose in the kidneys. This causes excess glucose to be excreted in the urine, which lowers blood sugar levels. Dapagliflozin also offers the benefit of potential weight loss and blood pressure reduction in some individuals.
  • This combination therapy offers a dual approach to managing blood sugar, addressing different pathways in the body to achieve better glycemic control. LINERO D 10/5MG is typically prescribed when diet and exercise alone are not sufficient to manage blood sugar levels effectively. It is crucial to use this medicine under the guidance of a healthcare professional who can monitor its effectiveness and any potential side effects.
  • Always follow your doctor's instructions regarding dosage and timing. Common side effects can include urinary tract infections, yeast infections, and increased urination. Discuss any concerns or pre-existing conditions with your doctor before starting LINERO D 10/5MG TABLET 10'S.

Uses of LINERO D 10/5MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering blood sugar levels
  • Improving glycemic control
  • Management of high blood sugar
  • Increasing insulin sensitivity

How LINERO D 10/5MG TABLET 10'S Works

  • LINERO D 10/5MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Linagliptin and Dapagliflozin, each working through different mechanisms to achieve better glycemic control.
  • Linagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that inactivates incretin hormones. Incretins, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood glucose levels are high and suppress glucagon secretion from the liver. By inhibiting DPP-4, Linagliptin increases the levels of active incretins in the body. This leads to enhanced insulin secretion and decreased glucagon secretion in a glucose-dependent manner, meaning it only works when blood sugar is elevated. As a result, Linagliptin helps lower blood glucose levels after meals and throughout the day without the risk of hypoglycemia (low blood sugar) when used alone.
  • Dapagliflozin, on the other hand, is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. By blocking SGLT2, Dapagliflozin reduces the reabsorption of glucose, causing excess glucose to be excreted in the urine. This mechanism lowers blood sugar levels and provides additional benefits, such as weight loss and blood pressure reduction. Dapagliflozin works independently of insulin, making it effective even in individuals with insulin resistance or reduced insulin production.
  • The combination of Linagliptin and Dapagliflozin in LINERO D 10/5MG TABLET 10'S provides a dual approach to managing blood sugar. Linagliptin enhances insulin secretion and suppresses glucagon, while Dapagliflozin promotes glucose excretion. This synergistic effect can lead to significant improvements in glycemic control, as measured by HbA1c levels, and a reduced risk of diabetes-related complications.
  • It's important to note that LINERO D 10/5MG TABLET 10'S should be used as part of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring of blood sugar levels. Patients should follow their doctor's instructions carefully and report any side effects or concerns.

Side Effects of LINERO D 10/5MG TABLET 10'SArrow

Possible side effects of LINERO D 10/5MG TABLET may include: * Hypoglycemia (low blood sugar) * Gastrointestinal issues (nausea, vomiting, diarrhea, abdominal pain) * Headache * Upper respiratory tract infection * Urinary tract infection * Peripheral edema (swelling in the extremities) * Weight gain * Joint pain (arthralgia) * Muscle pain (myalgia) * Back pain * Dizziness * Fatigue * Increased cough * Elevated liver enzymes * Pancreatitis (inflammation of the pancreas) - rare but serious * Allergic reactions (rash, itching, hives) - rare * Vitamin B12 deficiency (with long-term use) * Blurred vision This is not an exhaustive list, and you should consult your doctor if you experience any unusual symptoms while taking this medication.

Safety Advice for LINERO D 10/5MG TABLET 10'SArrow

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Allergies

Allergies

Consult your Doctor

Dosage of LINERO D 10/5MG TABLET 10'SArrow

  • The recommended dosage of LINERO D 10/5MG TABLET 10'S is typically one tablet daily, but this can vary depending on the individual's condition, severity of diabetes, kidney function, and other medications they may be taking. It is crucial to adhere strictly to the dosage prescribed by your physician. Do not self-adjust the dosage, even if you feel your condition is improving or worsening.
  • LINERO D 10/5MG TABLET 10'S should be swallowed whole with a glass of water, preferably at the same time each day. Consistency in timing helps maintain steady blood glucose levels. The tablet can be taken with or without food; however, taking it with food may help reduce the chance of stomach upset. If you experience nausea, taking it after meals might be beneficial.
  • If you miss a dose of LINERO D 10/5MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this can increase the risk of side effects.
  • Your physician may adjust your dosage over time based on your blood glucose levels and overall response to the medication. Regular monitoring of blood sugar is essential while taking LINERO D 10/5MG TABLET 10'S. Follow your doctor’s instructions meticulously, and attend all scheduled follow-up appointments.
  • Certain factors may influence your dosage requirements. These include changes in diet, exercise levels, or the introduction of new medications. Always inform your doctor about any lifestyle changes or new medications you are taking, as these could impact the effectiveness of LINERO D 10/5MG TABLET 10'S.
  • Take 'LINERO D 10/5MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of LINERO D 10/5MG TABLET 10'S?Arrow

  • If you miss a dose of LINERO D 10/5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store LINERO D 10/5MG TABLET 10'S?Arrow

  • Keep LINERO D 10/5MG TAB 1X10 away from the reach of children and pets.
  • Store LINERO D 10/5MG TAB 1X10 at room temperature.

Benefits of LINERO D 10/5MG TABLET 10'SArrow

  • LINERO D 10/5MG TABLET 10'S offers a dual-action approach to managing type 2 diabetes, combining the benefits of linagliptin and dapagliflozin into a single convenient tablet. This combination therapy provides synergistic effects, leading to improved glycemic control compared to either medication used alone.
  • Linagliptin, a DPP-4 inhibitor, works by increasing the levels of incretin hormones in the body. These hormones stimulate the release of insulin from the pancreas when blood sugar levels are high and reduce the secretion of glucagon, a hormone that raises blood sugar. By enhancing the body's natural ability to regulate blood sugar, linagliptin helps to lower A1c levels and improve overall glucose control.
  • Dapagliflozin, an SGLT2 inhibitor, works by blocking the reabsorption of glucose in the kidneys. This causes excess glucose to be excreted in the urine, lowering blood sugar levels. Dapagliflozin also offers additional benefits, such as weight loss and blood pressure reduction, which are particularly beneficial for individuals with type 2 diabetes who are often at increased risk for cardiovascular complications.
  • The combination of linagliptin and dapagliflozin in LINERO D 10/5MG TABLET 10'S provides comprehensive glycemic control by addressing multiple pathways involved in glucose regulation. This can lead to significant improvements in A1c levels, fasting blood sugar, and postprandial blood sugar.
  • Beyond glycemic control, LINERO D 10/5MG TABLET 10'S offers several other potential benefits. Dapagliflozin's mechanism of action can lead to weight loss, which can improve insulin sensitivity and overall metabolic health. The reduction in blood pressure associated with dapagliflozin can also reduce the risk of cardiovascular events, a major concern for individuals with type 2 diabetes.
  • LINERO D 10/5MG TABLET 10'S is typically taken once daily, making it a convenient option for many individuals. Its effectiveness and ease of use can improve adherence to treatment, leading to better long-term outcomes. However, it's important to note that LINERO D 10/5MG TABLET 10'S should be used in conjunction with lifestyle modifications, such as diet and exercise, to achieve optimal results.
  • In summary, LINERO D 10/5MG TABLET 10'S provides a comprehensive approach to managing type 2 diabetes by combining the complementary mechanisms of linagliptin and dapagliflozin. This combination therapy offers improved glycemic control, potential weight loss, blood pressure reduction, and convenient once-daily dosing, making it a valuable tool in the management of type 2 diabetes and associated cardiovascular risks. As always, discuss with your doctor to ensure this medication is right for you.

How to use LINERO D 10/5MG TABLET 10'SArrow

  • LINERO D 10/5MG TABLET 10'S should be taken orally, usually once daily. It's crucial to follow your doctor's prescribed dosage and timing. This medication can be taken with or without food, but consistency in timing each day is recommended to maintain stable blood sugar levels. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Before starting LINERO D, inform your doctor about all other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, as drug interactions can occur. Pay close attention to your body's response to the medication, and promptly report any unusual side effects or concerns to your healthcare provider.
  • Regular monitoring of blood sugar levels is essential while taking LINERO D. Your doctor may also recommend periodic blood tests to assess kidney and liver function. Adhering to a healthy diet and regular exercise regimen can significantly enhance the effectiveness of this medication in managing your blood sugar levels. If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It is very important to strictly adhere to the diet and exercise regimen advised by your doctor. This will help you manage your blood sugar levels effectively. Also, if you experience any symptoms of hypoglycemia (low blood sugar) such as dizziness, sweating, or confusion, consult your doctor immediately. Long-term use of LINERO D requires regular check-ups and monitoring to ensure the medication remains effective and safe for you.
  • Ensure the medication is stored in a cool, dry place, away from direct sunlight and moisture, and out of reach of children. Always consult your healthcare provider for personalized advice and guidance regarding the use of LINERO D 10/5MG TABLET 10'S.

Quick Tips for LINERO D 10/5MG TABLET 10'SArrow

  • **Take LINERO D 10/5MG TABLET 10'S as prescribed:** Always adhere to your doctor's instructions regarding dosage and timing. Do not self-medicate or alter the dosage without consulting your healthcare provider. Taking it at the same time each day helps maintain consistent blood levels and maximizes effectiveness.
  • **Monitor blood glucose regularly:** LINERO D 10/5MG TABLET 10'S helps manage blood sugar levels, but regular monitoring is crucial. Keep a log of your blood glucose readings and share it with your doctor to help them assess the medication's effectiveness and adjust your treatment plan if needed. Use a reliable glucose meter and follow the manufacturer's instructions carefully.
  • **Be mindful of potential side effects:** Common side effects may include nausea, diarrhea, or headache. More serious side effects are rare but possible. If you experience persistent or severe side effects, such as symptoms of hypoglycemia (low blood sugar) or allergic reactions (rash, itching, swelling), seek immediate medical attention. Do not ignore any unusual symptoms.
  • **Maintain a healthy lifestyle:** LINERO D 10/5MG TABLET 10'S works best when combined with a healthy diet and regular exercise. Follow a balanced meal plan that includes plenty of fruits, vegetables, and whole grains. Engage in at least 30 minutes of moderate-intensity exercise most days of the week. Consult a registered dietitian or certified personal trainer for personalized guidance.
  • **Inform your doctor about other medications:** Drug interactions can affect how LINERO D 10/5MG TABLET 10'S works. Before starting the medication, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. This will help your doctor identify and manage any potential interactions and ensure your safety.

Food Interactions with LINERO D 10/5MG TABLET 10'SArrow

  • LINERO D 10/5MG TABLET 10'S does not typically have significant interactions with food. It can be taken with or without food. However, it is advisable to maintain a consistent approach, either always with food or always without food, to ensure consistent absorption of the medication.

FAQs

What is Linero D 10/5mg Tablet 10's?Arrow

Linero D 10/5mg Tablet 10's is a combination of two medicines: Dapagliflozin and Sitagliptin. It is used to control high blood sugar levels in adults with type 2 diabetes mellitus.

How to use Linero D 10/5mg Tablet 10's?Arrow

Linero D 10/5mg Tablet 10's should be taken in the dose and duration as advised by your doctor. It can be taken with or without food, but it is best to take it at the same time every day.

What are the common side effects of Linero D 10/5mg Tablet 10's?Arrow

The common side effects of Linero D 10/5mg Tablet 10's include nausea, vomiting, diarrhea, stomach pain, and headache. Inform your doctor if these side effects persist or become severe.

Is Linero D 10/5mg Tablet 10's safe for patients with kidney disease?Arrow

Linero D 10/5mg Tablet 10's should be used with caution in patients with kidney disease. Dose adjustments may be required. Consult your doctor before using.

Is Linero D 10/5mg Tablet 10's safe during pregnancy?Arrow

The safety of Linero D 10/5mg Tablet 10's during pregnancy has not been established. It should only be used if the potential benefits outweigh the risks. Consult your doctor.

How to store Linero D 10/5mg Tablet 10's?Arrow

Store Linero D 10/5mg Tablet 10's at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can Linero D 10/5mg Tablet 10's interact with other medications?Arrow

Linero D 10/5mg Tablet 10's can interact with certain medications, such as insulin and sulfonylureas. Inform your doctor about all the medications you are taking.

What to do if a dose of Linero D 10/5mg Tablet 10's is missed?Arrow

If you miss a dose of Linero D 10/5mg Tablet 10's, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can Linero D 10/5mg Tablet 10's be used for type 1 diabetes?Arrow

No, Linero D 10/5mg Tablet 10's is not used to treat type 1 diabetes. It is only for type 2 diabetes.

What precautions should I take while taking Linero D 10/5mg Tablet 10's?Arrow

While taking Linero D 10/5mg Tablet 10's, monitor your blood sugar levels regularly, drink plenty of water, and maintain a healthy diet.

Can Linero D 10/5mg Tablet 10's cause weight gain?Arrow

Linero D 10/5mg Tablet 10's is not likely to cause weight gain. In fact, some people may experience weight loss with it.

Can Linero D 10/5mg Tablet 10's cause low blood sugar (hypoglycemia)?Arrow

Linero D 10/5mg Tablet 10's is not likely to cause hypoglycemia on its own, but it can occur if taken with other diabetes medications like insulin or sulfonylureas.

Is it safe to drink alcohol with Linero D 10/5mg Tablet 10's?Arrow

Drinking alcohol with Linero D 10/5mg Tablet 10's is not recommended, as it can increase the risk of low blood sugar.

Can Linero D 10/5mg Tablet 10's cause urinary tract infections (UTIs)?Arrow

Yes, Linero D 10/5mg Tablet 10's can increase the risk of urinary tract infections (UTIs). Inform your doctor if you experience symptoms of a UTI.

Should Linero D 10/5mg Tablet 10's be stopped abruptly?Arrow

No, Linero D 10/5mg Tablet 10's should not be stopped abruptly. Always consult your doctor before stopping the medication.

References

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EMA - Trajenta (linagliptin) EPAR. European Medicines Agency assessment report for linagliptin, one of the ingredients in LINERO D.

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FDA - Tradjenta (linagliptin) Label. US Food and Drug Administration label information for linagliptin.

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Gallwitz, C., et al. (2012). Linagliptin: clinical use and patient perspectives. Vascular health and risk management, 8, 11–18.

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Taskinen, M. R., Rosenstock, J., Tamminen, I., Ali, A., & Lewin, A. J. (2014). Safety and efficacy of linagliptin as add-on therapy to metformin in Asian patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled study. Diabetes, metabolic syndrome and obesity : targets and therapy, 7, 219–228.

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DrugBank - Linagliptin. DrugBank entry for Linagliptin, providing chemical and pharmacological information.

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FDA - Glucophage (metformin hydrochloride) Label. US Food and Drug Administration label information for metformin hydrochloride.

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LiverTox - Metformin. National Institute of Diabetes and Digestive and Kidney Diseases information on metformin and liver toxicity.

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UpToDate - Metformin drug information. Clinical information about metformin including mechanism of action, dosage and side effects

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INTAS PHARMACEUTICALS LIMITED

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