SITARA M 100/500MG TABLET 10'S
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SITARA M 100/500MG TABLET 10'S
SITARA M 100/500MG TABLET 10'S
SITARA M 100/500MG TABLET 10'S
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SITARA M 100/500MG TABLET 10'S

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SITARA M 100/500MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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174.75

₹148.54

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About SITARA M 100/500MG TABLET 10'S

  • SITARA M 100/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and improve the body's response to insulin. This medication is prescribed when diet and exercise alone are not sufficient to manage blood sugar effectively.
  • SITARA M contains two active ingredients: Sitagliptin and Metformin. Sitagliptin is a DPP-4 inhibitor that works by increasing the release of insulin from the pancreas and decreasing the secretion of glucagon, a hormone that raises blood sugar levels. Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity in the muscles, allowing for better glucose uptake.
  • The combination of Sitagliptin and Metformin provides a dual mechanism of action, addressing different aspects of type 2 diabetes. By improving insulin secretion and sensitivity while reducing glucose production, SITARA M effectively lowers blood sugar levels and helps maintain glycemic control. This can lead to a reduced risk of diabetes-related complications.
  • SITARA M 100/500MG TABLET is typically taken orally, once or twice daily, with meals to minimize gastrointestinal side effects. It's crucial to follow your doctor's instructions regarding dosage and timing. Common side effects may include nausea, diarrhea, stomach upset, and headache. It's important to discuss any existing medical conditions or medications you are taking with your doctor before starting SITARA M.
  • This medication is a valuable tool in managing type 2 diabetes, but it should be used in conjunction with a healthy lifestyle, including a balanced diet and regular physical activity. Regular monitoring of blood sugar levels and kidney function is also recommended while taking SITARA M.

Uses of SITARA M 100/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance associated with polycystic ovary syndrome (PCOS) (off-label use)

How SITARA M 100/500MG TABLET 10'S Works

  • SITARA M 100/500MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines Sitagliptin and Metformin, each working through different mechanisms to achieve optimal glycemic control. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors, while Metformin is a biguanide.
  • Sitagliptin enhances the body's natural ability to lower blood sugar. After a meal, the body releases incretin hormones, which stimulate the release of insulin from the pancreas and reduce the secretion of glucagon from the liver. DPP-4 inhibitors like Sitagliptin work by blocking the enzyme DPP-4, which breaks down incretin hormones. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This, in turn, leads to increased insulin release when blood sugar is high and decreased glucagon secretion, ultimately helping to lower blood sugar levels after meals.
  • Metformin, on the other hand, primarily works by reducing the amount of glucose produced by the liver. It also improves the body's sensitivity to insulin, allowing cells to use glucose more effectively. Specifically, Metformin decreases hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis. Gluconeogenesis is the process by which the liver produces glucose from non-carbohydrate sources, while glycogenolysis is the breakdown of glycogen (stored glucose) into glucose. Additionally, Metformin enhances insulin sensitivity in peripheral tissues, such as muscle, facilitating glucose uptake and utilization. By improving insulin sensitivity, Metformin helps lower blood sugar levels, especially in individuals with insulin resistance, a common characteristic of type 2 diabetes.
  • The synergistic effect of Sitagliptin and Metformin provides comprehensive blood sugar control. Sitagliptin addresses post-meal glucose spikes by enhancing insulin secretion and suppressing glucagon release, while Metformin tackles background glucose levels by reducing hepatic glucose production and improving insulin sensitivity. Together, they help maintain stable blood sugar levels throughout the day and night. This combination is particularly useful for patients who require more than one medication to manage their diabetes effectively. Consistent use of SITARA M 100/500MG TABLET 10'S, along with a healthy diet and regular exercise, can significantly improve glycemic control and reduce the risk of diabetes-related complications.

Side Effects of SITARA M 100/500MG TABLET 10'SArrow

Common side effects of Sitara M may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, and drowsiness. Less common side effects can involve skin rashes, itching, changes in liver function tests, and rarely, lactic acidosis (symptoms include rapid breathing, nausea, vomiting, and abdominal pain). In very rare cases, serious allergic reactions, such as angioedema (swelling of the face, lips, tongue, or throat) and Stevens-Johnson syndrome (a severe skin rash), may occur. Other potential side effects include hypoglycemia (low blood sugar) and vitamin B12 deficiency with long-term use. Always consult your doctor if you experience any unusual or persistent symptoms while taking this medication.

Safety Advice for SITARA M 100/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use SITARA M 100/500MG TABLET if you are allergic to it.

Dosage of SITARA M 100/500MG TABLET 10'SArrow

  • The recommended dosage of 'SITARA M 100/500MG TABLET 10'S' varies depending on individual patient factors, including the severity of the condition being treated, kidney function, and other medications being taken. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Typically, the starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. Your doctor may gradually increase the dosage based on your blood glucose levels and overall response to the medication.
  • The maximum recommended daily dose should not exceed the amount prescribed by your doctor. Consistent timing of doses is vital for maintaining stable blood glucose levels. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for a missed one. Regular monitoring of blood glucose levels is essential while taking 'SITARA M 100/500MG TABLET 10'S', to assess the effectiveness of the medication and to make any necessary dosage adjustments.
  • It is also important to inform your doctor about any other medications, including over-the-counter drugs and herbal supplements, you are currently taking, as they may interact with 'SITARA M 100/500MG TABLET 10'S'. Follow a healthy diet and exercise regularly while taking this medication to achieve optimal blood glucose control. In case of any side effects, consult your physician immediately.
  • Take 'SITARA M 100/500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of SITARA M 100/500MG TABLET 10'S?Arrow

  • If you miss a dose of SITARA M 100/500MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store SITARA M 100/500MG TABLET 10'S?Arrow

  • Keep SITARA M 100/500MG TAB 1X10 away from the reach of children and pets.
  • Store SITARA M 100/500MG TAB 1X10 at room temperature.

Benefits of SITARA M 100/500MG TABLET 10'SArrow

  • SITARA M 100/500MG TABLET 10'S is a combination medicine primarily used to manage type 2 diabetes mellitus, especially in individuals whose blood sugar levels are not adequately controlled by diet and exercise alone. It combines two active ingredients, Sitagliptin and Metformin, each working through different mechanisms to lower blood glucose levels and improve glycemic control. One of the primary benefits of SITARA M is its ability to effectively lower blood sugar levels. Metformin reduces glucose production in the liver and improves insulin sensitivity, allowing the body to use insulin more efficiently. Sitagliptin enhances the levels of incretin hormones, which stimulate insulin release and decrease glucagon secretion, both of which help lower blood sugar levels after meals. The dual action of these medications provides a comprehensive approach to glucose management.
  • By improving insulin sensitivity and reducing glucose production, SITARA M helps to achieve better glycemic control over time. Regular use, as directed by a healthcare provider, can lead to a more stable blood sugar profile, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). This stability is essential for preventing long-term complications associated with poorly controlled diabetes.
  • SITARA M can help to reduce the risk of long-term complications associated with diabetes, such as cardiovascular diseases, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). Effective management of blood sugar levels is crucial in minimizing these risks, and SITARA M aids in achieving this goal when combined with a healthy lifestyle.
  • Compared to using either Sitagliptin or Metformin alone, SITARA M often provides a more significant reduction in blood sugar levels. The synergistic effect of the two medications targets multiple pathways involved in glucose metabolism, resulting in improved overall glycemic control. This can be particularly beneficial for patients who need more aggressive treatment to reach their target blood sugar levels.
  • For many individuals, taking a single combination tablet like SITARA M is more convenient than taking two separate medications. This can improve adherence to the prescribed treatment plan, as it simplifies the daily routine. Better adherence leads to more consistent blood sugar control and improved health outcomes.
  • Metformin, one of the components of SITARA M, has been associated with modest weight loss or weight neutrality in some individuals. This can be a significant advantage for people with type 2 diabetes who are often overweight or obese. Sitagliptin generally does not cause weight gain, making SITARA M a favorable option for those concerned about weight management.
  • SITARA M is generally well-tolerated by most individuals. Common side effects are usually mild and may include gastrointestinal symptoms such as nausea, diarrhea, or abdominal discomfort, which often subside as the body adjusts to the medication. Serious side effects are rare but should be promptly reported to a healthcare provider.
  • SITARA M can be used as part of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring of blood sugar levels. It supports lifestyle modifications by helping to maintain blood sugar control, making it easier to adhere to dietary recommendations and exercise routines. This holistic approach enhances the overall effectiveness of diabetes management.

How to use SITARA M 100/500MG TABLET 10'SArrow

  • SITARA M 100/500MG TABLET 10'S is designed for oral administration. It is crucial to adhere to your doctor's prescribed dosage and duration of treatment for optimal results. Typically, this medication is taken once or twice daily, preferably with meals, to minimize potential gastrointestinal discomfort.
  • Swallow the tablet whole with a full glass of water. Avoid crushing, chewing, or breaking the tablet, as this can affect the release of the medication and potentially alter its efficacy. Consistency in timing is key; try to take SITARA M 100/500MG TABLET 10'S at the same time(s) each day to maintain a steady level of medication in your system.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose entirely and continue with your regular dosing schedule. Do not double your dose to compensate for a missed one. Doubling up on doses can lead to adverse effects.
  • It's essential to continue taking SITARA M 100/500MG TABLET 10'S even if you feel well, unless your doctor advises otherwise. Do not abruptly stop taking the medication, as this could lead to a worsening of your condition. Long-term management of your condition often requires consistent medication use.
  • Regular monitoring by your doctor is important while you are taking SITARA M 100/500MG TABLET 10'S. This may involve blood tests and other assessments to evaluate your response to the medication and to monitor for any potential side effects. Inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential drug interactions.
  • Store SITARA M 100/500MG TABLET 10'S at room temperature, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets. If you have any questions or concerns about how to use SITARA M 100/500MG TABLET 10'S, consult your doctor or pharmacist for clarification.

Quick Tips for SITARA M 100/500MG TABLET 10'SArrow

  • Take SITARA M 100/500MG TABLET as prescribed by your doctor, usually once or twice daily, with meals to minimize stomach upset. Consistency in timing is key for optimal blood sugar control.
  • SITARA M 100/500MG TABLET combines two medications, sitagliptin and metformin. Sitagliptin enhances insulin release, while metformin reduces glucose production by the liver and improves insulin sensitivity. This dual action effectively lowers blood sugar levels.
  • Monitor your blood sugar regularly as directed by your healthcare provider. This helps track your response to SITARA M 100/500MG TABLET and allows for timely adjustments to your treatment plan. Keep a record of your readings to share with your doctor.
  • Be aware of potential side effects. Common side effects include nausea, diarrhea, stomach upset, and headache. Serious side effects are rare but can include lactic acidosis (more common with metformin) and pancreatitis (more common with sitagliptin). Contact your doctor immediately if you experience severe abdominal pain, persistent nausea, vomiting, or difficulty breathing.
  • Follow a healthy lifestyle while taking SITARA M 100/500MG TABLET. This includes a balanced diet, regular physical activity, and weight management. Avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of side effects. Discuss any changes in your diet or exercise routine with your doctor.

Food Interactions with SITARA M 100/500MG TABLET 10'SArrow

  • SITARA M 100/500MG TABLET 10'S is generally safe to take with food. However, it is recommended to take this medicine with meals to minimize potential gastrointestinal side effects such as nausea or stomach upset. Consistent timing with meals can also help maintain stable blood sugar levels.
  • Avoid excessive alcohol consumption while taking SITARA M 100/500MG TABLET 10'S, as it can increase the risk of hypoglycemia (low blood sugar) and other adverse effects. Consult your doctor for specific dietary advice tailored to your condition and treatment plan.

FAQs

What is SITARA M 100/500MG TABLET 10'S used for?

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SITARA M 100/500MG TABLET 10'S is primarily used to treat type 2 diabetes mellitus. It helps control blood sugar levels, especially when diet and exercise are not sufficient.

What are the active ingredients in SITARA M 100/500MG TABLET 10'S?

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SITARA M 100/500MG TABLET 10'S contains two active ingredients: Sitagliptin (100mg) and Metformin (500mg).

What are the common side effects of SITARA M 100/500MG TABLET 10'S?

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Common side effects of SITARA M 100/500MG TABLET 10'S may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is SITARA M 100/500MG TABLET 10'S safe for people with kidney problems?

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SITARA M 100/500MG TABLET 10'S is not recommended for people with kidney problems, as Metformin can worsen kidney function.

How should SITARA M 100/500MG TABLET 10'S be stored?

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SITARA M 100/500MG TABLET 10'S should be stored at room temperature, away from moisture and direct sunlight.

What happens if I miss a dose of SITARA M 100/500MG TABLET 10'S?

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If you miss a dose of SITARA M 100/500MG TABLET 10'S, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Should SITARA M 100/500MG TABLET 10'S be taken with food?

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It is generally recommended to take SITARA M 100/500MG TABLET 10'S with food to minimize stomach upset.

Is SITARA M 100/500MG TABLET 10'S safe during pregnancy?

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The safety of SITARA M 100/500MG TABLET 10'S during pregnancy has not been established. It should only be used if the benefits outweigh the risks and under the supervision of a doctor.

Can SITARA M 100/500MG TABLET 10'S be taken with other diabetes medications?

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SITARA M 100/500MG TABLET 10'S can be taken with other diabetes medications, but only under the advice of a doctor. The dosage may need to be adjusted.

Does SITARA M 100/500MG TABLET 10'S cause weight gain?

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SITARA M 100/500MG TABLET 10'S does not typically cause weight gain. In some cases, Metformin may lead to weight loss.

What happens if I overdose on SITARA M 100/500MG TABLET 10'S?

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Overdosing on SITARA M 100/500MG TABLET 10'S can cause serious side effects like hypoglycemia (low blood sugar) and lactic acidosis. Seek immediate medical attention.

Does SITARA M 100/500MG TABLET 10'S cause dizziness?

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Some people may experience dizziness after taking SITARA M 100/500MG TABLET 10'S, especially if they are taking other medications that lower blood sugar.

Can I drink alcohol while taking SITARA M 100/500MG TABLET 10'S?

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It is not recommended to drink alcohol while taking SITARA M 100/500MG TABLET 10'S, as it can increase the risk of hypoglycemia and lactic acidosis.

Can SITARA M 100/500MG TABLET 10'S be taken on an empty stomach?

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Taking SITARA M 100/500MG TABLET 10'S on an empty stomach may cause stomach upset, so it's recommended to take it with food.

Should I consult a doctor before taking SITARA M 100/500MG TABLET 10'S if I am taking other medication?

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Yes, it is important to consult a doctor before taking SITARA M 100/500MG TABLET 10'S if you are taking any other medication, as medications can interact with each other.

References

Book Icon

DrugBank: Sitagliptin. Provides detailed chemical and pharmacological information on Sitagliptin, including its mechanism of action, metabolism, and drug interactions.

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National Center for Biotechnology Information (NCBI): Efficacy and safety of metformin and sitagliptin combination therapy in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Research article evaluating the combined effects of Metformin and Sitagliptin in treating type 2 diabetes.

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FDA (Food and Drug Administration) Label: JANUVIA (sitagliptin) tablets. Provides prescribing information, including clinical studies, indications, dosages, contraindications, and adverse reactions.

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European Medicines Agency (EMA): Januvia. Public Assessment Report. Contains detailed scientific assessment and regulatory information about Sitagliptin.

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RxList: Januvia. Contains information about Sitagliptin, including side effects, drug interactions, and dosage.

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Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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