SITAWOK M XR 500MG TABLET 15'S

How SITAWOK M XR 500MG TABLET 15'S Works

• SITAWOK M XR 500MG TABLET 15'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: sitagliptin and metformin, each working through different mechanisms to achieve optimal glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine in response to food intake. These hormones stimulate insulin release from the pancreas and reduce glucagon secretion from the liver, both of which help lower blood sugar levels. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This leads to increased insulin secretion when blood sugar is high and decreased glucagon secretion, resulting in improved blood sugar control after meals and throughout the day.
• Metformin, on the other hand, is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces hepatic glucose production by inhibiting gluconeogenesis (the process by which the liver produces glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Metformin also enhances insulin sensitivity in peripheral tissues, such as muscle and fat, allowing cells to utilize glucose more effectively. Additionally, it slows down the absorption of glucose from the intestines, further contributing to its blood sugar-lowering effects.
• The extended-release (XR) formulation of SITAWOK M XR 500MG TABLET 15'S allows for a slower and more consistent release of metformin into the bloodstream. This helps to minimize gastrointestinal side effects, such as nausea and diarrhea, which are sometimes associated with immediate-release metformin. The combination of sitagliptin and metformin XR provides a comprehensive approach to managing blood sugar levels by addressing multiple aspects of glucose metabolism.
• In summary, SITAWOK M XR 500MG TABLET 15'S works by: 1) Sitagliptin increasing incretin hormone levels, leading to increased insulin release and decreased glucagon secretion. 2) Metformin reducing glucose production in the liver, improving insulin sensitivity, and slowing glucose absorption. 3) The extended-release formulation providing a steady release of metformin to reduce side effects. This synergistic action helps to effectively lower and maintain healthy blood sugar levels in individuals with type 2 diabetes, especially when combined with a healthy diet and regular exercise.

The most common side effects of SITAWOK M XR 500MG Tablet are nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects include: Headache, Dizziness, Constipation, Upper respiratory tract infection, Back pain, Joint pain, Muscle pain, Increased sweating. Less common but potentially serious side effects include: Lactic acidosis (symptoms include feeling very weak, tired or uncomfortable; unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, irregular heartbeat, dizziness or lightheadedness), Pancreatitis (severe stomach pain that may spread to your back), Liver problems (persistent nausea, vomiting, stomach pain, unusual tiredness, dark urine, yellowing of the skin or eyes). Allergic reactions (rash, itching, swelling).

• If you miss a dose of SITAWOK M XR 500MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep SITAWOK M XR 500MG TAB 1X15 away from the reach of children and pets.
• Store SITAWOK M XR 500MG TAB 1X15 at room temperature.

• Take SITAWOK M XR 500MG TABLET 15'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a glass of water. It is usually taken once daily with the evening meal to minimize gastrointestinal side effects. Following the prescribed dosage and timing is crucial for optimal blood sugar control.
• Consistency is key! Take SITAWOK M XR 500MG TABLET 15'S at the same time each day to maintain a steady level of medication in your body. Setting a daily reminder on your phone or incorporating it into your routine (e.g., with dinner) can help you remember. Avoid skipping doses, as this can lead to fluctuations in your blood sugar levels.
• SITAWOK M XR 500MG TABLET 15'S works best when combined with a healthy lifestyle. This includes a balanced diet low in sugars and refined carbohydrates, regular physical activity (at least 30 minutes most days of the week), and maintaining a healthy weight. Talk to your doctor or a registered dietitian for personalized guidance on diet and exercise.
• Be aware of the potential side effects of SITAWOK M XR 500MG TABLET 15'S. Common side effects include nausea, diarrhea, stomach upset, and headache. If these side effects persist or worsen, inform your doctor. More serious side effects, such as lactic acidosis (rare but potentially life-threatening), require immediate medical attention. Learn the signs and symptoms of lactic acidosis (e.g., weakness, muscle pain, trouble breathing) and seek emergency care if you experience them.
• Regular monitoring of your blood sugar levels is essential while taking SITAWOK M XR 500MG TABLET 15'S. This helps you and your doctor assess how well the medication is working and adjust your treatment plan if necessary. Follow your doctor's recommendations for blood sugar testing frequency and target ranges. Keep a record of your blood sugar readings and share them with your healthcare provider at your appointments.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting SITAWOK M XR 500MG TABLET 15'S. Certain medications can interact with this medicine, affecting its effectiveness or increasing the risk of side effects. This includes over-the-counter medications, vitamins, and herbal remedies.
• If you are scheduled for any surgery or medical procedure (including dental work), inform your doctor that you are taking SITAWOK M XR 500MG TABLET 15'S. It might be necessary to temporarily discontinue the medication before the procedure to minimize the risk of complications.
• Store SITAWOK M XR 500MG TABLET 15'S at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired. Dispose of expired or unused medication properly according to your local regulations.

• SITAWOK M XR 500MG TABLET 15'S is generally taken with food to decrease the chances of stomach upset.
• Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a serious side effect.
• There are no specific food restrictions, but maintaining a consistent diet is advisable for better blood sugar control.