SITARED M XR 100/500MG TABLET 10'S

How SITARED M XR 100/500MG TABLET 10'S Works

• SITARED M XR 100/500MG TABLET 10'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Sitagliptin and Metformin Hydrochloride. Each component works through different mechanisms to achieve better glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones released in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar levels. When blood sugar levels are high, incretin hormones signal the pancreas to release insulin. They also reduce the amount of glucagon released. Glucagon is a hormone that raises blood sugar levels by prompting the liver to release stored glucose. By inhibiting the DPP-4 enzyme, Sitagliptin slows down the breakdown of incretin hormones, thereby prolonging their activity. This results in increased insulin release and decreased glucagon secretion in a glucose-dependent manner, ultimately helping to lower blood sugar levels after meals.
• Metformin Hydrochloride is a biguanide antihyperglycemic agent. It primarily works by decreasing glucose production in the liver. The liver is a significant source of glucose in the body, and in people with type 2 diabetes, the liver often produces excessive amounts of glucose. Metformin reduces hepatic glucose production by suppressing gluconeogenesis (the formation of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Metformin also improves insulin sensitivity in peripheral tissues such as muscle and fat. This means that the body's cells become more responsive to insulin, allowing them to take up glucose from the bloodstream more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines after a meal, which further contributes to lower postprandial blood sugar spikes.
• The extended-release (XR) formulation of SITARED M XR is designed to release the medication slowly over an extended period. This helps to provide a more consistent level of medication in the bloodstream throughout the day and reduces the frequency of dosing. The combination of Sitagliptin and Metformin XR provides a synergistic effect, addressing multiple aspects of blood sugar control. Sitagliptin enhances insulin secretion and suppresses glucagon release, while Metformin reduces hepatic glucose production and improves insulin sensitivity. Together, they help to lower both fasting and postprandial blood sugar levels, leading to improved overall glycemic control in patients with type 2 diabetes. It is crucial to use SITARED M XR 100/500MG TABLET 10'S as directed by your healthcare provider and to adhere to lifestyle modifications such as diet and exercise for optimal management of your condition.

Common side effects of SITARED M XR 100/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, constipation, upper respiratory tract infection, and skin reactions like rash or itching. Less common but potentially serious side effects include pancreatitis, severe allergic reactions (anaphylaxis), lactic acidosis, and liver problems. If you experience persistent or severe side effects, seek immediate medical attention. This is not an exhaustive list, and other side effects may occur.

• If you miss a dose of SITARED M XR 100/500MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for the missed one.
• Missing a dose can lead to fluctuations in your blood sugar levels, so it's important to try and take your medication as prescribed.

• Keep SITARED M XR 100/500MG TAB 1X10 away from the reach of children and pets.
• Store SITARED M XR 100/500MG TAB 1X10 at room temperature.

• Take SITARED M XR exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water. Consistency is key, so take it at the same time each day, preferably with your evening meal, to maintain steady blood sugar levels and aid absorption. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and resume your regular schedule. Never double up on doses.
• While taking SITARED M XR, carefully monitor your blood sugar levels regularly as directed by your healthcare provider. Keep a log of your readings to track your progress and share it with your doctor during appointments. This information helps your doctor adjust your dosage and treatment plan as needed. Also, be alert for signs of hypoglycemia (low blood sugar), such as sweating, shaking, rapid heartbeat, and confusion. Carry a quick source of sugar, like glucose tablets or juice, with you at all times.
• SITARED M XR works best when combined with a healthy lifestyle. Follow a balanced diet that is low in processed foods, sugary drinks, and unhealthy fats, and rich in fruits, vegetables, lean proteins, and whole grains. Regular physical activity, such as brisk walking, jogging, or cycling, can significantly improve your body's response to insulin and help manage blood sugar levels. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Consult with your doctor or a certified diabetes educator for personalized diet and exercise recommendations.
• Be aware of potential side effects while on SITARED M XR. Common side effects may include nausea, diarrhea, stomach upset, and headache. These are usually mild and temporary. However, if you experience persistent or severe side effects, such as severe abdominal pain, jaundice (yellowing of the skin or eyes), or signs of an allergic reaction (rash, itching, swelling), seek immediate medical attention. Report any unusual symptoms to your doctor promptly.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting SITARED M XR. Certain medications can interact with sitagliptin and metformin, affecting their effectiveness or increasing the risk of side effects. Pay special attention to medications that affect blood sugar, such as insulin, sulfonylureas, and corticosteroids. Also, avoid excessive alcohol consumption while taking SITARED M XR, as it can increase the risk of lactic acidosis, a rare but serious side effect.

• SITARED M XR 100/500MG TABLET 10'S should be taken with food to decrease the chance of stomach upset.
• Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of lactic acidosis.
• Follow your doctor's dietary recommendations carefully while on this medication.