SUITGLIP M XR 100/500 TABLET 10'S

How SUITGLIP M XR 100/500 TABLET 10'S Works

• SUITGLIP M XR 100/500 Tablet is a combination medication designed to manage type 2 diabetes mellitus. It combines two active ingredients: Sitagliptin and Metformin Hydrochloride. Each component works through different mechanisms to lower blood glucose levels effectively.
• Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 inhibitors work by increasing the amount of incretin hormones released in the body. Incretins are natural hormones that help to regulate blood sugar levels, particularly after a meal. They stimulate the release of insulin from the pancreas and reduce the secretion of glucagon from the liver. Insulin helps the body use glucose for energy or store it for later use, while glucagon signals the liver to release stored glucose into the bloodstream. By inhibiting DPP-4, Sitagliptin prolongs the activity of incretin hormones, leading to better blood sugar control. Sitagliptin's action is glucose-dependent, meaning it primarily works when blood sugar levels are high, reducing the risk of hypoglycemia (low blood sugar).
• Metformin Hydrochloride is a biguanide that works primarily by reducing glucose production in the liver. It also improves insulin sensitivity in muscle tissue, allowing cells to use glucose more effectively. Metformin does not stimulate insulin secretion directly; instead, it reduces hepatic glucose output and enhances peripheral glucose uptake. This helps to lower blood sugar levels without the risk of causing hypoglycemia when used alone. Additionally, Metformin can slow down the absorption of glucose from the intestines into the bloodstream. It can also have a modest effect on weight loss in some individuals.
• When Sitagliptin and Metformin are combined in SUITGLIP M XR, they offer a dual mechanism of action that addresses multiple aspects of type 2 diabetes. Sitagliptin enhances insulin secretion and reduces glucagon levels, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic effect leads to better overall glycemic control compared to using either medication alone. The 'XR' in SUITGLIP M XR stands for extended-release, which means the medication is released slowly into the body, providing a more consistent effect throughout the day and reducing the frequency of dosing. This can improve patient compliance and convenience.
• In summary, SUITGLIP M XR 100/500 Tablet works by enhancing the effects of incretin hormones (Sitagliptin) and reducing glucose production in the liver and improving insulin sensitivity (Metformin). This combination helps to regulate blood sugar levels effectively in individuals with type 2 diabetes, providing better glycemic control when used in conjunction with diet and exercise.

Like all medicines, SUITGLIP M XR 100/500 TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Headache * Dizziness * Heartburn * Low blood sugar (hypoglycemia) - symptoms may include shakiness, sweating, anxiety, blurred vision, tingling lips, paleness, confusion, or headache. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Skin rash * Itching * Urticaria (hives) * Fatigue * Sleepiness * Constipation * Flu-like symptoms **Rare Side Effects (may affect up to 1 in 1,000 people):** * Lactic acidosis (build-up of lactic acid in the blood) - symptoms may include rapid breathing, stomach pain, nausea, vomiting, sleepiness, and weakness. * Abnormal liver function tests * Inflammation of the liver (hepatitis) * Jaundice (yellowing of the skin and eyes) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe allergic reactions (anaphylaxis) - symptoms may include difficulty breathing, swelling of the face, lips, tongue, or throat, and rash. * Decrease in vitamin B12 levels * Erythema multiforme (a type of skin rash) * Stevens-Johnson syndrome (a severe skin reaction) * Angioedema (swelling under the skin) * Pemphigoid (blistering skin disorder) **If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed above.**

• If you miss a dose of SUITGLIP M XR 100/500 TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SUITGLIP M XR 100/500MG TAB 1X10 away from the reach of children and pets.
• Store SUITGLIP M XR 100/500MG TAB 1X10 at room temperature.

• Take SUITGLIP M XR 100/500 Tablet as prescribed by your doctor. Follow the dosage instructions carefully and do not exceed the recommended dose to avoid potential side effects. Consistency is key for optimal blood sugar control.
• SUITGLIP M XR 100/500 Tablet should be taken with food, preferably with your first main meal of the day (breakfast or lunch). This helps reduce the likelihood of stomach upset and improves the absorption of the medication.
• Regularly monitor your blood sugar levels as advised by your healthcare provider. Keep a record of your readings and share them with your doctor during your appointments. This helps in assessing how well the medication is working and allows for dosage adjustments if needed.
• Maintain a healthy lifestyle while taking SUITGLIP M XR 100/500 Tablet. This includes following a balanced diet, engaging in regular physical activity (at least 30 minutes of moderate exercise most days of the week), and managing stress levels. These habits can significantly improve blood sugar control.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times. If you experience these symptoms, consume the fast-acting sugar and consult your doctor promptly.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration is important for overall health and can also help regulate blood sugar levels. Aim for at least 8 glasses of water daily, unless otherwise instructed by your doctor.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Some substances can interact with SUITGLIP M XR 100/500 Tablet and affect its effectiveness or increase the risk of side effects.
• Do not skip meals while taking SUITGLIP M XR 100/500 Tablet. Skipping meals can lead to fluctuations in blood sugar levels and may increase the risk of hypoglycemia.
• Store SUITGLIP M XR 100/500 Tablet in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets.
• Attend all scheduled follow-up appointments with your doctor and undergo any recommended lab tests. These check-ups are essential for monitoring your overall health and ensuring that the medication is working effectively.

• SUITGLIP M XR 100/500 TABLET 10'S should be taken with food to avoid stomach upset.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of side effects such as low blood sugar.
• There are no specific food restrictions, but maintaining a consistent carbohydrate intake is important for blood sugar control.