AMARYL MP2 TABLET 20'S
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AMARYL MP2 TABLET 20'SAMARYL MP2 TABLET 20'SAMARYL MP2 TABLET 20'S
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AMARYL MP2 TABLET 20'S

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AMARYL MP2 TABLET 20'S

By SANOFI INDIA LIMITED

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538.44

₹457.67

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About AMARYL MP2 TABLET 20'S

  • AMARYL MP2 Tablet is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise are not enough to control blood sugar levels. It combines the power of Glimepiride and Metformin to provide a dual-pronged approach to managing your blood glucose. This medication helps your body use insulin more effectively, lowering blood sugar levels.
  • Glimepiride stimulates the release of insulin from the pancreas, helping to lower blood sugar levels after meals. Metformin, on the other hand, reduces glucose production in the liver and improves insulin sensitivity in the body's tissues. Together, they offer comprehensive glycemic control.
  • AMARYL MP2 Tablet is typically taken once or twice daily with meals, as prescribed by your doctor. The dosage will depend on your individual needs and response to treatment. It's crucial to follow your doctor's instructions carefully and not to exceed the recommended dose. Regular monitoring of blood sugar levels is essential while taking this medication to ensure optimal results and prevent potential complications.
  • Besides taking AMARYL MP2 Tablet, it's also important to maintain a healthy lifestyle by following a balanced diet, exercising regularly, and managing stress levels. These lifestyle modifications can significantly improve blood sugar control and overall health.
  • AMARYL MP2 Tablet may cause some side effects, such as nausea, diarrhea, or stomach upset. These side effects are usually mild and temporary, but if they persist or worsen, you should inform your doctor. It's also important to be aware of the signs and symptoms of hypoglycemia (low blood sugar), such as sweating, shaking, or confusion, and to take appropriate measures if they occur.
  • This medicine is a prescription drug and should only be taken under the guidance of a healthcare professional. It is not suitable for everyone, and your doctor will assess your medical history and current medications to determine if it's the right choice for you. Do not share this medication with others, even if they have similar symptoms.

Uses of AMARYL MP2 TABLET 20'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Management of diabetes in adults
  • Improving blood sugar control in combination with diet and exercise

How AMARYL MP2 TABLET 20'S Works

  • AMARYL MP2 Tablet 20's is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: glimepiride, metformin, and pioglitazone, each working through different mechanisms to control blood sugar levels. This multi-pronged approach helps to address various aspects of the disease, providing comprehensive glycemic control.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) from the blood enter cells, where it can be used for energy. By increasing insulin secretion, glimepiride directly lowers blood glucose levels, particularly after meals. This action is dependent on the presence of functional beta cells in the pancreas. It essentially squeezes the pancreas to produce more insulin to combat high blood sugar.
  • Metformin, a biguanide, works primarily by reducing glucose production in the liver. The liver is a major source of glucose, especially during fasting and between meals. Metformin also improves the body's sensitivity to insulin, allowing cells to use glucose more efficiently. Additionally, it slightly reduces glucose absorption from the intestines. Metformin acts on multiple fronts, reducing the amount of sugar released into the bloodstream and helping the body utilize the insulin it produces more effectively, thereby lowering blood sugar levels. It doesn't stimulate insulin secretion, so it's less likely to cause hypoglycemia (low blood sugar) when used alone.
  • Pioglitazone, a thiazolidinedione (TZD), enhances insulin sensitivity in peripheral tissues such as muscle and fat. This means that cells become more responsive to insulin, allowing them to take up more glucose from the bloodstream. Pioglitazone also reduces glucose production in the liver, complementing the action of metformin. It works by activating a receptor called PPARgamma, which regulates genes involved in glucose and lipid metabolism. By improving insulin sensitivity, pioglitazone helps to lower blood sugar levels and improve overall glycemic control over time. Unlike glimepiride, pioglitazone targets insulin resistance, a core defect in type 2 diabetes.
  • In summary, AMARYL MP2 Tablet 20's works through three distinct pathways: glimepiride stimulates insulin release, metformin reduces glucose production and improves insulin sensitivity, and pioglitazone enhances insulin sensitivity. This synergistic action makes it a powerful tool for managing type 2 diabetes, helping patients achieve and maintain target blood sugar levels. Always take this medication as prescribed by your doctor, and regularly monitor your blood sugar levels to ensure optimal control.

Side Effects of AMARYL MP2 TABLET 20'SArrow

Common side effects of Amaryl MP2 Tablet may include: Hypoglycemia (low blood sugar), Nausea, Diarrhea, Abdominal pain. Less common but potentially serious side effects may include: Allergic reactions (rash, itching, swelling), Liver problems (jaundice, dark urine, fatigue), Blood disorders (anemia, leukopenia, thrombocytopenia), Visual disturbances, Headache, Dizziness. This is not an exhaustive list, and other side effects may occur. Contact your doctor if you experience any unusual symptoms while taking Amaryl MP2 Tablet.

Safety Advice for AMARYL MP2 TABLET 20'SArrow

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Allergies

Allergies

Inform your doctor if you are allergic to AMARYL MP2 TABLET 20'S or any of its ingredients.

Dosage of AMARYL MP2 TABLET 20'SArrow

  • The dosage of AMARYL MP2 TABLET 20'S is highly individualized and must be determined by your physician based on your blood glucose levels, overall health, and response to treatment. Typically, the initial dose is low, and gradually increased to achieve optimal glycemic control. It is usually taken once or twice daily, preferably with meals to minimize the risk of hypoglycemia. The maximum recommended daily dose should not be exceeded.
  • The starting dose often begins with 1mg of glimepiride, and then, if necessary, increased based on blood glucose monitoring. Metformin dosage is also adjusted based on individual needs and tolerance, usually starting with a low dose and gradually increasing it. Pioglitazone is typically started at 15mg or 30mg once daily.
  • Regular monitoring of blood glucose levels is essential during treatment with AMARYL MP2 TABLET 20'S to ensure the dosage is appropriate. Your doctor may adjust the dosage based on these readings, as well as other factors such as diet, exercise, and other medications you may be taking. It is important to follow your doctor's instructions carefully and attend all scheduled appointments.
  • The tablets should be swallowed whole with a glass of water and not crushed or chewed. If a dose is missed, it should be taken as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Take 'AMARYL MP2 TABLET 20'S' only as per the prescription by your physician only

What if I miss my dose of AMARYL MP2 TABLET 20'S?Arrow

  • If you miss a dose of AMARYL MP2 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store AMARYL MP2 TABLET 20'S?Arrow

  • Keep AMARYL MP2 TAB 1X20 away from the reach of children and pets.
  • Store AMARYL MP2 TAB 1X20 at room temperature.

Benefits of AMARYL MP2 TABLET 20'SArrow

  • AMARYL MP2 TABLET 20'S is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise are not enough to control blood sugar levels effectively. It combines the power of three active ingredients to provide comprehensive glycemic control and improve overall health outcomes for individuals with diabetes.
  • One of the primary benefits of AMARYL MP2 TABLET 20'S is its ability to lower blood sugar levels. By stimulating the release of insulin from the pancreas, it helps the body utilize glucose more efficiently, preventing hyperglycemia and reducing the risk of diabetes-related complications. Regular use of this medication can lead to improved HbA1c levels, a key indicator of long-term blood sugar control.
  • Beyond glycemic control, AMARYL MP2 TABLET 20'S offers additional benefits for individuals with type 2 diabetes. It helps improve insulin sensitivity, allowing cells to respond better to insulin and take up glucose from the bloodstream. This can lead to reduced insulin resistance, a common problem in type 2 diabetes, and improve overall metabolic function.
  • This medication also helps regulate glucose production in the liver. By reducing the amount of glucose released into the bloodstream, it helps prevent postprandial hyperglycemia (high blood sugar after meals) and maintain stable blood sugar levels throughout the day. This can be particularly beneficial for individuals who experience significant fluctuations in blood sugar levels after eating.
  • AMARYL MP2 TABLET 20'S offers the convenience of a single tablet containing multiple medications. This can simplify the treatment regimen, improve adherence to medication, and reduce the pill burden for individuals with diabetes. The combination approach also allows for synergistic effects, where the different medications work together to achieve better blood sugar control than any single medication alone.
  • Furthermore, this medicine can contribute to weight management in individuals with type 2 diabetes. Some of its components have been shown to promote weight loss or prevent weight gain, which can be particularly beneficial for overweight or obese individuals with diabetes. Maintaining a healthy weight is essential for improving insulin sensitivity and reducing the risk of diabetes-related complications.
  • AMARYL MP2 TABLET 20'S may also have beneficial effects on cardiovascular health. Some studies have suggested that certain components of this medication can reduce the risk of heart disease and stroke, common complications of diabetes. By improving blood sugar control, reducing inflammation, and improving lipid profiles, this medication can help protect against cardiovascular events.
  • In addition to its direct effects on blood sugar and cardiovascular health, AMARYL MP2 TABLET 20'S can improve overall quality of life for individuals with type 2 diabetes. By effectively managing blood sugar levels, this medication can reduce the symptoms of diabetes, such as fatigue, frequent urination, and excessive thirst. This can lead to increased energy levels, improved sleep quality, and a greater sense of well-being.

How to use AMARYL MP2 TABLET 20'SArrow

  • AMARYL MP2 Tablet 20'S should be taken orally, usually once daily, with the first main meal of the day. This helps to prevent stomach upset and ensures optimal absorption of the medication. It is crucial to swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this can affect the release of the medication and potentially alter its effectiveness and safety profile.
  • Your doctor will determine the appropriate dosage based on your individual needs and blood glucose levels. It's vital to adhere strictly to your doctor's instructions regarding dosage and timing. Do not increase or decrease the dose without consulting your physician, even if you feel your blood sugar is well-controlled or not. Consistent timing of administration each day is key for maintaining stable blood glucose levels.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Doubling the dose can lead to dangerously low blood sugar levels (hypoglycemia).
  • While taking AMARYL MP2, it's important to monitor your blood glucose levels regularly, as directed by your healthcare provider. Keep a record of your readings and share them with your doctor during your check-ups. This will help them assess how well the medication is working and adjust your treatment plan if necessary. Make sure to follow all diet and exercise recommendations from your doctor to ensure this medicine works best.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they can interact with AMARYL MP2. Certain medications can increase or decrease the effects of AMARYL MP2 on blood sugar levels. Also, discuss any existing medical conditions you have, especially kidney or liver problems, before starting AMARYL MP2. If you experience any unusual side effects, such as severe hypoglycemia, allergic reactions, or persistent gastrointestinal issues, contact your doctor immediately.

Quick Tips for AMARYL MP2 TABLET 20'SArrow

  • Take AMARYL MP2 TABLET 20'S as prescribed by your doctor. It's usually taken once daily, with or without food, preferably at the same time each day to maintain consistent blood sugar levels. Consistency is key!
  • AMARYL MP2 TABLET 20'S is a combination medicine containing glimepiride, metformin, and pioglitazone. It works by increasing insulin release, decreasing glucose production in the liver, and improving insulin sensitivity. Understanding how it works helps you appreciate its role in managing your diabetes.
  • Monitor your blood sugar levels regularly as advised by your doctor. Keep a log of your readings and share it with them during your check-ups. This helps in adjusting the dosage of AMARYL MP2 TABLET 20'S if needed and ensures optimal control of your blood sugar.
  • Be aware of the potential side effects of AMARYL MP2 TABLET 20'S, such as hypoglycemia (low blood sugar), nausea, diarrhea, and weight gain. If you experience any severe or persistent side effects, inform your doctor immediately. Carry a source of quick-acting glucose, like candy or juice, in case of hypoglycemia.
  • Follow a healthy diet and exercise regularly while taking AMARYL MP2 TABLET 20'S. A balanced diet low in sugars and carbohydrates, combined with regular physical activity, can significantly improve your blood sugar control and overall health. Remember, medicine works best when combined with lifestyle changes!
  • Inform your doctor about all other medications, supplements, or herbal products you are taking before starting AMARYL MP2 TABLET 20'S. Drug interactions can affect how AMARYL MP2 TABLET 20'S works and increase the risk of side effects. Transparency is crucial for safe and effective treatment.
  • Attend all scheduled appointments with your doctor and laboratory for regular check-ups. These visits allow your doctor to monitor your progress, adjust your medication if necessary, and screen for potential complications of diabetes. Regular monitoring is vital for long-term health.

Food Interactions with AMARYL MP2 TABLET 20'SArrow

  • To avoid stomach upset, it is recommended to take AMARYL MP2 TABLET 20'S with food or immediately after a meal.
  • Consistent timing of meals is important while taking this medication. Try to maintain a regular eating schedule.
  • Avoid excessive alcohol consumption while taking AMARYL MP2 TABLET 20'S, as it can increase the risk of hypoglycemia (low blood sugar).
  • Be mindful of your carbohydrate intake. AMARYL MP2 TABLET 20'S works best when combined with a balanced diet.
  • If you experience nausea or gastrointestinal discomfort, try taking the tablet with a small snack.

FAQs

What is Amaryl MP2 Tablet 20'S?Arrow

Amaryl MP2 Tablet 20'S is a medication used to treat type 2 diabetes. It contains a combination of Glimepiride, Metformin, and Pioglitazone.

What is Amaryl MP2 Tablet 20'S used for?Arrow

Amaryl MP2 Tablet 20'S is used to control blood sugar levels in people with type 2 diabetes.

How does Amaryl MP2 Tablet 20'S work?Arrow

Amaryl MP2 Tablet 20'S works in three ways: it increases the amount of insulin released by the pancreas, it makes the body more sensitive to insulin, and it decreases the amount of glucose produced by the liver.

What are the common side effects of Amaryl MP2 Tablet 20'S?Arrow

Common side effects of Amaryl MP2 Tablet 20'S include: low blood sugar (hypoglycemia), nausea, diarrhea, and stomach pain.

Are there any serious side effects of Amaryl MP2 Tablet 20'S?Arrow

Serious side effects of Amaryl MP2 Tablet 20'S are rare, but can include: liver problems, heart problems, and lactic acidosis.

What precautions should I take while taking Amaryl MP2 Tablet 20'S?Arrow

While taking Amaryl MP2 Tablet 20'S, avoid drinking alcohol, check your blood sugar levels regularly, and tell your doctor about any unusual side effects.

What happens if I miss a dose of Amaryl MP2 Tablet 20'S?Arrow

If you miss a dose of Amaryl MP2 Tablet 20'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can Amaryl MP2 Tablet 20'S interact with other medications?Arrow

Amaryl MP2 Tablet 20'S can interact with certain other medications, such as insulin, sulfonylureas, and beta-blockers. Tell your doctor about all the medications you are taking.

How should I store Amaryl MP2 Tablet 20'S?Arrow

Store Amaryl MP2 Tablet 20'S at room temperature, away from heat and moisture.

Can pregnant or breastfeeding women take Amaryl MP2 Tablet 20'S?Arrow

Amaryl MP2 Tablet 20'S should not be taken by pregnant or breastfeeding women.

Is Amaryl MP2 Tablet 20'S safe for children?Arrow

Amaryl MP2 Tablet 20'S is not recommended for children.

What are the alternatives to Amaryl MP2 Tablet 20'S?Arrow

Alternatives to Amaryl MP2 Tablet 20'S include other diabetes medications, such as metformin, sulfonylureas, and insulin.

Can Amaryl MP2 Tablet 20'S cause weight gain?Arrow

Amaryl MP2 Tablet 20'S can cause weight gain in some people.

What are the symptoms of an overdose of Amaryl MP2 Tablet 20'S?Arrow

Symptoms of an overdose of Amaryl MP2 Tablet 20'S can include low blood sugar, confusion, seizures, and loss of consciousness.

How long does it take for Amaryl MP2 Tablet 20'S to work?Arrow

It may take a few days for Amaryl MP2 Tablet 20'S to start working.

References

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FDA drug label for AMARYL M (glimepiride and metformin hydrochloride) tablets. Contains information on clinical pharmacology, indications and usage, contraindications, warnings and precautions, adverse reactions, drug interactions, and dosage and administration.

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DrugBank entry for Glimepiride. Comprehensive information on glimepiride, including its mechanism of action, pharmacokinetics, and therapeutic uses.

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DrugBank entry for Metformin. Comprehensive information on metformin, including its mechanism of action, pharmacokinetics, and therapeutic uses.

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A Randomized Controlled Trial to Compare the Efficacy and Safety of Teneligliptin plus Metformin versus Glimepiride plus Metformin in Patients with Type 2 Diabetes Mellitus. Research article comparing Glimepiride and Metformin combination therapy with another combination therapy.

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European Medicines Agency (EMA) summary on Glimepiride containing medicinal products. Overview of Glimepiride, usage, safety and efficacy.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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