ENDOFORMIN PG 2MG TABLET 10'S
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ENDOFORMIN PG 2MG TABLET 10'S
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ENDOFORMIN PG 2MG TABLET 10'S

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ENDOFORMIN PG 2MG TABLET 10'S

By PRECIA PHARMA PRIVATE LIMITED

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133

₹113.05

15 % OFF

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Product DetailsArrow

About ENDOFORMIN PG 2MG TABLET 10'S

  • ENDOFORMIN PG 2MG TABLET is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels effectively. This medication combines two active ingredients: metformin and pioglitazone, working through different mechanisms to lower blood glucose and improve insulin sensitivity.
  • Metformin, a biguanide, reduces glucose production in the liver and enhances insulin sensitivity in peripheral tissues, allowing cells to utilize glucose more effectively. Pioglitazone, a thiazolidinedione (TZD), works by increasing the sensitivity of muscle and fat cells to insulin, which helps the body use insulin more efficiently and lowers blood sugar levels. By combining these two medications, ENDOFORMIN PG 2MG TABLET provides a dual-action approach to managing blood sugar, addressing both insulin resistance and glucose overproduction.
  • This medication is typically prescribed as part of a comprehensive diabetes management plan that includes dietary changes, regular exercise, and blood glucose monitoring. It's crucial to take ENDOFORMIN PG 2MG TABLET as directed by your healthcare provider. Dosage and frequency will depend on individual factors such as blood sugar levels, overall health, and response to treatment. Regular monitoring of blood sugar levels and kidney function is essential while taking this medication to ensure its effectiveness and safety.
  • ENDOFORMIN PG 2MG TABLET is available in tablet form and should be taken orally with food to minimize gastrointestinal side effects. Common side effects may include nausea, diarrhea, abdominal discomfort, and loss of appetite. It's important to discuss any potential side effects or concerns with your doctor. This medication is not suitable for individuals with severe kidney or liver problems, heart failure, or certain other medical conditions. Always inform your healthcare provider about all medications, supplements, and medical conditions before starting ENDOFORMIN PG 2MG TABLET.

Uses of ENDOFORMIN PG 2MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • Managing insulin resistance associated with polycystic ovary syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (potential benefit)

How ENDOFORMIN PG 2MG TABLET 10'S Works

  • ENDOFORMIN PG 2MG TABLET 10'S is a combination medicine designed to manage type 2 diabetes mellitus effectively. It combines three active ingredients: Metformin, Pioglitazone, and Glimepiride, each working through different mechanisms to lower blood glucose levels.
  • Metformin is a biguanide that primarily reduces hepatic glucose production. This means it decreases the amount of glucose your liver releases into the bloodstream. Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. It also slows down the absorption of glucose from the intestines after a meal. Unlike some other diabetes medications, Metformin does not typically cause hypoglycemia (low blood sugar) when used alone because it doesn't stimulate insulin release.
  • Pioglitazone is a thiazolidinedione (TZD) that enhances insulin sensitivity in the body. It works by activating peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor that regulates genes involved in glucose and lipid metabolism. By activating PPARγ, Pioglitazone increases the uptake and utilization of glucose in peripheral tissues, such as adipose tissue and muscles. It also reduces glucose production in the liver. Pioglitazone helps to improve glycemic control and can also have beneficial effects on lipid profiles.
  • Glimepiride is a sulfonylurea that stimulates the release of insulin from the beta cells in the pancreas. It works by binding to sulfonylurea receptors on the beta cells, leading to the closure of ATP-sensitive potassium channels. This, in turn, causes depolarization of the beta cell membrane and an influx of calcium ions, which triggers the release of insulin. Glimepiride helps to lower blood glucose levels, particularly after meals, by increasing insulin secretion. However, it's important to monitor for hypoglycemia, as sulfonylureas can sometimes cause low blood sugar, especially if meals are skipped or delayed.
  • In summary, ENDOFORMIN PG 2MG TABLET 10'S works by addressing multiple aspects of type 2 diabetes. Metformin reduces glucose production in the liver and improves insulin sensitivity, Pioglitazone enhances insulin sensitivity in peripheral tissues, and Glimepiride stimulates insulin release from the pancreas. This combination helps to lower blood glucose levels effectively, improving glycemic control in individuals with type 2 diabetes mellitus. It's crucial to use this medication as prescribed by your healthcare provider and to monitor blood glucose levels regularly to ensure optimal management of your condition.

Side Effects of ENDOFORMIN PG 2MG TABLET 10'SArrow

Common side effects of ENDOFORMIN PG 2MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, altered taste, and hypoglycemia (low blood sugar). Some patients might experience metallic taste, weakness, headache, or dizziness. Serious but less common side effects include lactic acidosis (symptoms like rapid breathing, stomach pain, muscle cramps), allergic reactions (rash, itching, swelling), and liver problems. Report any persistent or severe side effects to your doctor immediately.

Safety Advice for ENDOFORMIN PG 2MG TABLET 10'SArrow

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Allergies

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Dosage of ENDOFORMIN PG 2MG TABLET 10'SArrow

  • The dosage of ENDOFORMIN PG 2MG TABLET 10'S is highly individualized and should be determined by your physician based on your specific needs and response to treatment. It is typically taken orally, with meals, to minimize gastrointestinal side effects. The usual starting dose is often low, and gradually increased to achieve optimal blood glucose control. Your doctor will likely monitor your blood sugar levels regularly to adjust the dosage accordingly.
  • The typical starting dose might be one tablet once or twice daily, depending on your condition and other medications you may be taking. The maximum recommended daily dose should not be exceeded. It's crucial to follow your doctor's instructions precisely and not to alter the dosage on your own, even if you feel your blood sugar is well-controlled or not well-controlled. Changes in dosage should only be made under the guidance of a healthcare professional.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Consistent adherence to the prescribed dosage schedule is essential for maintaining stable blood sugar levels and preventing complications associated with diabetes. Always consult your doctor or pharmacist if you have any questions or concerns about your dosage.
  • Take 'ENDOFORMIN PG 2MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of ENDOFORMIN PG 2MG TABLET 10'S?Arrow

  • If you miss a dose of ENDOFORMIN PG 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ENDOFORMIN PG 2MG TABLET 10'S?Arrow

  • Keep ENDOFORMIN PG 2MG TAB 1X10 away from the reach of children and pets.
  • Store ENDOFORMIN PG 2MG TAB 1X10 at room temperature.

Benefits of ENDOFORMIN PG 2MG TABLET 10'SArrow

  • ENDOFORMIN PG 2MG TABLET 10'S is a combination medication specifically designed to manage type 2 diabetes mellitus. It combines the synergistic effects of metformin, pioglitazone, and glimepiride to offer comprehensive glycemic control and address multiple facets of the disease.
  • Metformin, a cornerstone in diabetes management, primarily reduces glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver synthesizes glucose from non-carbohydrate sources. Additionally, metformin enhances insulin sensitivity in peripheral tissues like muscles, allowing them to utilize glucose more efficiently. It also slows down glucose absorption from the intestines, further contributing to lower post-meal blood sugar levels. Unlike some other diabetes medications, metformin generally does not cause weight gain and may even promote modest weight loss, making it a favorable option for overweight or obese individuals with type 2 diabetes.
  • Pioglitazone belongs to the thiazolidinedione class of drugs and acts as an insulin sensitizer. It primarily works by improving the responsiveness of muscle, fat, and liver cells to insulin. This enhanced sensitivity allows insulin to function more effectively in transporting glucose from the bloodstream into these cells, thereby lowering blood glucose levels. Pioglitazone also helps to reduce insulin resistance, a common characteristic of type 2 diabetes. Furthermore, it may have beneficial effects on lipid profiles, potentially increasing high-density lipoprotein (HDL) cholesterol (the 'good' cholesterol) and decreasing triglycerides.
  • Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. It works by binding to specific receptors on pancreatic beta cells, triggering the release of insulin. This increased insulin secretion helps to lower blood glucose levels, particularly after meals. Glimepiride is effective in lowering blood sugar but carries a risk of hypoglycemia (low blood sugar), especially if meals are skipped or delayed, or if used in combination with other medications that lower blood sugar.
  • The combined action of these three drugs provides a multi-pronged approach to managing type 2 diabetes. Metformin reduces glucose production and improves insulin sensitivity, pioglitazone further enhances insulin sensitivity, and glimepiride stimulates insulin release. This comprehensive approach can lead to better glycemic control compared to using any of these medications alone. By effectively managing blood sugar levels, ENDOFORMIN PG 2MG TABLET 10'S helps reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • ENDOFORMIN PG 2MG TABLET 10'S offers the convenience of a single tablet containing three different medications, simplifying the treatment regimen for patients and potentially improving adherence. However, it's crucial to use this medication under the guidance of a healthcare professional, as it's essential to monitor blood glucose levels regularly and adjust the dosage as needed to avoid hypoglycemia or other adverse effects. Lifestyle modifications, including a healthy diet and regular exercise, remain fundamental components of diabetes management and should be followed in conjunction with medication.
  • In summary, ENDOFORMIN PG 2MG TABLET 10'S offers a comprehensive approach to managing type 2 diabetes by addressing multiple aspects of the disease through the combined action of metformin, pioglitazone, and glimepiride. It improves glycemic control, reduces the risk of diabetes-related complications, and simplifies the treatment regimen. However, it is essential to use it under medical supervision and in conjunction with lifestyle modifications.

How to use ENDOFORMIN PG 2MG TABLET 10'SArrow

  • ENDOFORMIN PG 2MG TABLET 10'S is a prescription medication used to manage blood sugar levels in individuals with type 2 diabetes. It is crucial to adhere to your doctor's instructions regarding dosage and timing. Generally, this medication is taken orally, usually once or twice daily, with meals to minimize potential gastrointestinal side effects. Swallow the tablet whole with a full glass of water, and do not crush, chew, or break it.
  • Consistency is key for optimal results. Try to take ENDOFORMIN PG 2MG TABLET 10'S at the same time(s) each day. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
  • While taking ENDOFORMIN PG 2MG TABLET 10'S, it's important to monitor your blood sugar levels regularly as directed by your healthcare provider. This helps ensure the medication is working effectively and allows for dosage adjustments if needed. Also, inform your doctor about any other medications, supplements, or herbal products you are taking, as they may interact with ENDOFORMIN PG 2MG TABLET 10'S.
  • Lifestyle modifications, including a healthy diet and regular exercise, are essential components of managing type 2 diabetes. ENDOFORMIN PG 2MG TABLET 10'S works best when combined with these lifestyle changes. Avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of side effects. Contact your doctor immediately if you experience any unusual or severe side effects, such as persistent nausea, vomiting, abdominal pain, or symptoms of hypoglycemia (low blood sugar).

Quick Tips for ENDOFORMIN PG 2MG TABLET 10'SArrow

  • Take ENDOFORMIN PG 2MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, as this can affect your blood sugar levels and overall health. Consistency is key for optimal results.
  • It's best to take ENDOFORMIN PG 2MG TABLET 10'S with meals to help reduce the risk of stomach upset. This medication can sometimes cause nausea, diarrhea, or abdominal pain, and taking it with food can minimize these side effects. If symptoms persist, inform your doctor.
  • ENDOFORMIN PG 2MG TABLET 10'S works best when combined with a healthy lifestyle. This includes a balanced diet, regular physical activity, and maintaining a healthy weight. Following a diet plan tailored to diabetes can greatly improve the effectiveness of the medication.
  • Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. Keeping track of your blood sugar readings will help you and your healthcare provider understand how well the medication is working and make any necessary adjustments to your treatment plan. Keep a log of your readings to share with your doctor.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, and confusion. Always carry a source of fast-acting sugar, such as glucose tablets or juice, with you. If you experience these symptoms, consume the sugary item immediately and inform your doctor.
  • ENDOFORMIN PG 2MG TABLET 10'S may interact with other medications, including over-the-counter drugs and herbal supplements. It is essential to inform your doctor about all the medications you are taking to avoid potential drug interactions. This includes prescription medications, over-the-counter drugs, and herbal supplements.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports overall health and can help your kidneys function properly. Check with your doctor regarding the appropriate amount of water intake, especially if you have kidney problems.
  • Attend all scheduled appointments with your doctor and diabetes educator. Regular check-ups are crucial for monitoring your condition and making necessary adjustments to your treatment plan. Do not miss these appointments to ensure optimal diabetes management.
  • Store ENDOFORMIN PG 2MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Proper storage helps maintain the medication's effectiveness. Keep out of reach of children to prevent accidental ingestion.
  • If you experience any unusual side effects or have concerns about taking ENDOFORMIN PG 2MG TABLET 10'S, contact your doctor immediately. Do not ignore any new or worsening symptoms, as they may require prompt medical attention.

Food Interactions with ENDOFORMIN PG 2MG TABLET 10'SArrow

  • ENDOFORMIN PG 2MG TABLET 10'S may cause gastrointestinal side effects like nausea, vomiting, and diarrhea. These side effects can be exacerbated if taken with food that is high in fat or sugar. It is generally recommended to take this medication with meals to help reduce the risk of stomach upset, but avoid excessively fatty or sugary foods.
  • Alcohol consumption should be avoided while taking ENDOFORMIN PG 2MG TABLET 10'S as it can increase the risk of lactic acidosis, a serious side effect. Consult your doctor for specific dietary recommendations.

FAQs

What is ENDOFORMIN PG 2MG TABLET 10'S?Arrow

ENDOFORMIN PG 2MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does ENDOFORMIN PG 2MG TABLET 10'S work?Arrow

This medicine works through a combination of three medicines: Metformin, Pioglitazone and Glimepiride. Metformin works by decreasing glucose production in the liver. Pioglitazone works by increasing sensitivity to insulin. Glimepiride works by increasing the release of insulin from the pancreas.

What are the common side effects of ENDOFORMIN PG 2MG TABLET 10'S?Arrow

Common side effects of ENDOFORMIN PG 2MG TABLET 10'S include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is ENDOFORMIN PG 2MG TABLET 10'S safe during pregnancy?Arrow

The safety of ENDOFORMIN PG 2MG TABLET 10'S during pregnancy is not known. Consult your doctor before using this medicine during pregnancy.

Is ENDOFORMIN PG 2MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether ENDOFORMIN PG 2MG TABLET 10'S passes into breast milk. Consult your doctor before using this medicine during breastfeeding.

How to store ENDOFORMIN PG 2MG TABLET 10'S?Arrow

Store ENDOFORMIN PG 2MG TABLET 10'S at room temperature, away from heat and moisture.

Is it safe to consume alcohol with ENDOFORMIN PG 2MG TABLET 10'S?Arrow

Consuming alcohol with ENDOFORMIN PG 2MG TABLET 10'S can lower blood sugar levels and cause other side effects. Consult your doctor before consuming alcohol with this medicine.

What happens if I miss a dose of ENDOFORMIN PG 2MG TABLET 10'S?Arrow

If you miss a dose of ENDOFORMIN PG 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

What are the symptoms of an overdose of ENDOFORMIN PG 2MG TABLET 10'S?Arrow

Symptoms of an overdose of ENDOFORMIN PG 2MG TABLET 10'S include low blood sugar, nausea, vomiting, diarrhea, stomach pain, and difficulty breathing.

Can ENDOFORMIN PG 2MG TABLET 10'S interact with other medications?Arrow

Yes, ENDOFORMIN PG 2MG TABLET 10'S can interact with other medications. Tell your doctor about all the medications you are taking, including prescription, over-the-counter medicines, and herbal products.

What precautions should I take while taking ENDOFORMIN PG 2MG TABLET 10'S?Arrow

While taking ENDOFORMIN PG 2MG TABLET 10'S, you should monitor your blood sugar levels regularly, eat a healthy diet, exercise regularly, and avoid alcohol.

Can I take ENDOFORMIN PG 2MG TABLET 10'S on an empty stomach?Arrow

It is best to take ENDOFORMIN PG 2MG TABLET 10'S with food. This reduces the chance of stomach upset.

How long does it take for ENDOFORMIN PG 2MG TABLET 10'S to show its effect?Arrow

It may take a few weeks for ENDOFORMIN PG 2MG TABLET 10'S to show its effect. It's important to be patient and continue taking the medication as prescribed to see an improvement in your blood sugar levels.

Can I stop taking ENDOFORMIN PG 2MG TABLET 10'S once my blood sugar levels are under control?Arrow

No, you should not stop taking ENDOFORMIN PG 2MG TABLET 10'S without consulting your doctor. Stopping the medication may cause your blood sugar levels to rise again.

Does ENDOFORMIN PG 2MG TABLET 10'S cause weight gain?Arrow

ENDOFORMIN PG 2MG TABLET 10'S may cause weight gain in some patients, particularly due to pioglitazone. Talk to your doctor if you are concerned about weight gain.

References

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DrugBank: Metformin and Pioglitazone Combination - Detailed drug information including mechanism of action, pharmacology, and interactions.

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Efficacy and safety of pioglitazone and metformin combination therapy in patients with type 2 diabetes mellitus: A systematic review and meta-analysis - A research article evaluating the efficacy and safety of the combination.

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US FDA Label: ACTOPLUS MET (pioglitazone and metformin hydrochloride) tablets, for oral use - Official FDA label providing detailed information on usage, dosage, and safety.

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ScienceDirect: Pioglitazone - Overview of pioglitazone, including its mechanism of action, therapeutic uses, and adverse effects

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ScienceDirect: Metformin - Overview of metformin, including its mechanism of action, therapeutic uses, and adverse effects

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European Medicines Agency (EMA): Competact - European public assessment report for a combination product containing pioglitazone and metformin.

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Ratings & Review

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

Reviewed on 05-12-2022

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(3/5)

Best for medicine and helpfull.😊

Dilip Darji

Reviewed on 02-02-2024

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(5/5)

Excellent 👍👍👍

ashok badhala

Reviewed on 26-11-2022

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(5/5)

One stop solution for medicine

Chintan Joshi

Reviewed on 16-01-2024

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(5/5)

Good experience with best medicine purchase at affordablee prices.

Aman Rohit M

Reviewed on 05-02-2024

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(5/5)


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PRECIA PHARMA PRIVATE LIMITED

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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