GLUCORYL MP 2MG TABLET 15'S
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GLUCORYL MP 2MG TABLET 15'SGLUCORYL MP 2MG TABLET 15'SGLUCORYL MP 2MG TABLET 15'SGLUCORYL MP 2MG TABLET 15'S
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GLUCORYL MP 2MG TABLET 15'S

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GLUCORYL MP 2MG TABLET 15'S

By ALKEM LABORATORIES LIMITED

MRP

259

₹220.15

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About GLUCORYL MP 2MG TABLET 15'S

  • GLUCORYL MP 2MG TABLET 15'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls blood sugar levels in adults when diet and exercise alone are not sufficient. This medication helps to prevent serious complications of diabetes, such as kidney damage, nerve problems, loss of limbs, and sexual function problems.
  • The tablet contains a combination of three active ingredients: Glimepiride, Metformin, and Pioglitazone. Glimepiride is a sulfonylurea that works by increasing the release of insulin from the pancreas, thereby lowering blood glucose. Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity, allowing the body to use insulin more effectively. Pioglitazone is a thiazolidinedione that works by improving the body's sensitivity to insulin, helping to control blood sugar levels.
  • GLUCORYL MP 2MG TABLET 15'S is typically taken orally, once or twice daily, with meals to minimize stomach upset. The dosage is determined by your doctor based on your medical condition, blood sugar levels, and response to treatment. It's crucial to follow your doctor's instructions carefully and not to adjust the dosage without consulting them. Regular blood sugar monitoring is essential while taking this medication to ensure optimal control and to detect any potential side effects.
  • Common side effects of GLUCORYL MP 2MG TABLET 15'S may include nausea, diarrhea, stomach upset, and headache. These side effects are usually mild and temporary. However, if they persist or become bothersome, you should inform your doctor. In rare cases, more serious side effects such as hypoglycemia (low blood sugar) can occur, so it's important to be aware of the symptoms (e.g., sweating, shaking, rapid heartbeat) and know how to treat them. Always carry a source of fast-acting sugar, such as glucose tablets or fruit juice.
  • Before taking GLUCORYL MP 2MG TABLET 15'S, inform your doctor about your complete medical history, including any kidney or liver problems, heart conditions, or allergies. This medication may not be suitable for everyone, and your doctor can determine if it's the right choice for you. It's also important to inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with GLUCORYL MP 2MG TABLET 15'S.

Uses of GLUCORYL MP 2MG TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Used in combination with diet and exercise
  • May be used in combination with other diabetes medications

How GLUCORYL MP 2MG TABLET 15'S Works

  • GLUCORYL MP 2MG TABLET 15'S is a combination medicine designed to manage type 2 diabetes mellitus. It contains three active ingredients: Glimepiride, Metformin, and Pioglitazone. Each component works through different mechanisms to lower blood glucose levels and improve overall glycemic control.
  • Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the blood into cells for energy. By increasing insulin secretion, glimepiride effectively lowers blood sugar levels, particularly after meals.
  • Metformin, a biguanide, works primarily by reducing glucose production in the liver. It also improves insulin sensitivity, allowing cells to utilize glucose more effectively. Additionally, metformin slows down the absorption of glucose from the intestines, further contributing to lower blood sugar levels. Metformin is often the first-line treatment for type 2 diabetes due to its effectiveness and relatively low risk of hypoglycemia (low blood sugar) when used alone.
  • Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It enhances insulin sensitivity in peripheral tissues, such as fat and muscle, making them more responsive to insulin's signal to take up glucose from the bloodstream. Pioglitazone also reduces glucose production in the liver, although to a lesser extent than metformin. By improving insulin sensitivity, pioglitazone helps lower blood sugar levels and can also have beneficial effects on other metabolic parameters.
  • The combined action of glimepiride, metformin, and pioglitazone addresses multiple aspects of type 2 diabetes. Glimepiride provides immediate insulin release to control post-meal glucose spikes, while metformin and pioglitazone work to improve insulin sensitivity and reduce glucose production over the long term. This synergistic effect can lead to better glycemic control compared to using any single medication alone.
  • It is crucial to take GLUCORYL MP 2MG TABLET 15'S as prescribed by your doctor. Dosage and timing will depend on your individual needs and response to treatment. Regular monitoring of blood glucose levels is essential to ensure the medication is working effectively and to adjust the dosage if necessary. Lifestyle modifications, such as diet and exercise, are also important components of diabetes management and should be followed in conjunction with medication.
  • Patients should be aware of potential side effects, which may include hypoglycemia (low blood sugar), gastrointestinal upset (nausea, diarrhea), and, less commonly, weight gain or fluid retention. It is important to discuss any concerns or side effects with your doctor.

Side Effects of GLUCORYL MP 2MG TABLET 15'SArrow

Possible side effects of GLUCORYL MP 2MG TABLET may include: * Hypoglycemia (low blood sugar): Symptoms can include shakiness, sweating, anxiety, blurred vision, rapid heartbeat, and confusion. This is a common side effect, especially when taken with other diabetes medications or if meals are skipped. * Gastrointestinal issues: Nausea, vomiting, diarrhea, constipation, abdominal pain, and loss of appetite are possible. * Metallic taste: Some individuals may experience a metallic taste in their mouth. * Headache * Dizziness * Skin reactions: Rash, itching, redness, and hives have been reported. * Weight gain * Edema (swelling): Swelling in the ankles and feet may occur. * Liver problems: In rare cases, GLUCORYL MP can cause liver problems, which may present as jaundice (yellowing of the skin and eyes), dark urine, and abdominal pain. * Blood disorders: Rarely, it can cause changes in blood cell counts. * Lactic acidosis: A very rare but serious side effect associated with metformin (one of the components of GLUCORYL MP). Symptoms include rapid breathing, abdominal pain, muscle cramps, and general weakness. This requires immediate medical attention.

Safety Advice for GLUCORYL MP 2MG TABLET 15'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it or any of its ingredients.

Dosage of GLUCORYL MP 2MG TABLET 15'SArrow

  • The dosage of GLUCORYL MP 2MG TABLET 15'S is highly individualized and should be determined by your physician based on your specific needs, blood glucose levels, and response to treatment. It is typically taken orally, once or twice daily, with meals to minimize gastrointestinal side effects. The starting dose is usually low and gradually increased as needed to achieve optimal glycemic control. Your doctor will monitor your blood sugar levels regularly to adjust the dosage accordingly.
  • The maximum recommended daily dose of GLUCORYL MP 2MG TABLET 15'S should not be exceeded. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Do not change the dosage or discontinue the medication without consulting your healthcare provider. Factors such as age, kidney function, liver function, and other medical conditions may influence the appropriate dosage.
  • If you miss a dose of GLUCORYL MP 2MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Regular monitoring of blood glucose levels is essential while taking this medication to ensure its effectiveness and prevent potential complications. It's important to maintain a healthy diet and exercise regularly while taking GLUCORYL MP 2MG TABLET 15'S. Take 'GLUCORYL MP 2MG TABLET 15'S' only as per the prescription by your physician only.

What if I miss my dose of GLUCORYL MP 2MG TABLET 15'S?Arrow

  • If you miss a dose of GLUCORYL MP 2MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store GLUCORYL MP 2MG TABLET 15'S?Arrow

  • Keep GLUCORYL MP 2MG TAB 1X15 away from the reach of children and pets.
  • Store GLUCORYL MP 2MG TAB 1X15 at room temperature.

Benefits of GLUCORYL MP 2MG TABLET 15'SArrow

  • GLUCORYL MP 2MG TABLET 15'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls high blood sugar levels and helps prevent serious complications of diabetes such as kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. This medication combines the power of three antidiabetic drugs – Glimepiride, Metformin, and Pioglitazone – each working through different mechanisms to achieve optimal blood sugar control.
  • Glimepiride stimulates the release of insulin from the pancreas. By prompting the pancreas to produce more insulin, it helps lower blood glucose levels, particularly after meals. This is crucial for managing postprandial hyperglycemia (high blood sugar after eating). Metformin, on the other hand, decreases glucose production in the liver and improves insulin sensitivity in the body's cells, allowing them to use glucose more effectively. This dual action helps lower both fasting and postprandial blood sugar levels.
  • Pioglitazone enhances insulin sensitivity in peripheral tissues like muscles and fat. By improving the body's response to insulin, it helps glucose enter cells more efficiently, thus reducing blood sugar levels. Additionally, it helps in improving lipid profile.
  • By targeting multiple pathways involved in blood sugar regulation, GLUCORYL MP 2MG TABLET 15'S provides comprehensive glycemic control. This is especially beneficial for individuals who may not achieve adequate control with single-agent therapy. The synergistic action of the three drugs ensures that blood sugar levels are kept within the target range, reducing the risk of long-term complications associated with diabetes.
  • Consistent use of GLUCORYL MP 2MG TABLET 15'S, as prescribed by your doctor, can lead to improved overall health and well-being. Maintaining stable blood sugar levels is vital for preventing damage to blood vessels and nerves, which can lead to a variety of complications. This medication not only helps in managing blood sugar but also contributes to improved energy levels and a better quality of life.
  • Furthermore, GLUCORYL MP 2MG TABLET 15'S may offer additional benefits such as a potential reduction in cardiovascular risk factors. Metformin, in particular, has been shown to have beneficial effects on cholesterol levels and blood pressure, further reducing the risk of heart disease in diabetic patients. Regular monitoring of blood sugar levels and adherence to a healthy lifestyle, including diet and exercise, are essential for maximizing the benefits of this medication.

How to use GLUCORYL MP 2MG TABLET 15'SArrow

  • GLUCORYL MP 2MG TABLET 15'S is a medication prescribed to manage type 2 diabetes. It's crucial to use this medicine as directed by your doctor or healthcare provider to achieve the best possible results. Typically, it is taken orally, usually once or twice daily, with meals to help lower blood sugar levels effectively. Adhering to a consistent schedule is essential for maintaining stable blood glucose control throughout the day. Always swallow the tablet whole with a full glass of water, and avoid crushing or chewing it, as this can affect how the medication is released and absorbed.
  • Before starting GLUCORYL MP 2MG TABLET 15'S, inform your doctor about any pre-existing medical conditions, particularly kidney or liver problems, as well as any other medications you are currently taking, including herbal supplements and over-the-counter drugs. This information is vital to prevent potential drug interactions and ensure your safety. Your doctor may need to adjust the dosage based on your kidney function or other factors.
  • During treatment with GLUCORYL MP 2MG TABLET 15'S, it's important to monitor your blood sugar levels regularly as directed by your healthcare provider. This monitoring helps track how well the medication is working and allows for timely adjustments to your treatment plan if necessary. Following a healthy diet and exercise plan, as recommended by your doctor or a registered dietitian, is also crucial for managing your diabetes effectively. Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion, and discuss with your doctor how to manage these symptoms if they occur.
  • Do not abruptly stop taking GLUCORYL MP 2MG TABLET 15'S without consulting your doctor, as this can lead to a sudden increase in blood sugar levels. If you experience any unusual side effects, such as persistent nausea, vomiting, abdominal pain, or yellowing of the skin or eyes (jaundice), seek medical attention promptly. Store GLUCORYL MP 2MG TABLET 15'S in a cool, dry place, away from direct sunlight and moisture, and keep it out of reach of children. Remember, this medication is just one part of a comprehensive diabetes management plan that includes diet, exercise, and regular medical check-ups.

Quick Tips for GLUCORYL MP 2MG TABLET 15'SArrow

  • **Take GLUCORYL MP 2MG TABLET 15'S as prescribed by your doctor:** Always adhere to the dosage and timing instructions provided by your healthcare professional. Do not self-adjust the dosage or discontinue the medication without consulting your doctor, as it can lead to fluctuations in blood sugar levels and potential health complications. Consistency is key to managing your diabetes effectively.
  • **Monitor your blood sugar levels regularly:** GLUCORYL MP 2MG TABLET 15'S helps manage blood sugar, but regular monitoring is essential to track your progress and make necessary adjustments to your diet and exercise routine. Keep a log of your readings and share it with your doctor during check-ups. This will help them fine-tune your treatment plan and ensure optimal blood sugar control.
  • **Follow a healthy diet and exercise plan:** GLUCORYL MP 2MG TABLET 15'S works best when combined with a balanced diet and regular physical activity. Focus on consuming whole grains, fruits, vegetables, and lean protein sources. Engage in at least 30 minutes of moderate-intensity exercise most days of the week. This synergistic approach will maximize the benefits of the medication and improve your overall health.
  • **Be aware of the symptoms of hypoglycemia (low blood sugar):** GLUCORYL MP 2MG TABLET 15'S can sometimes cause hypoglycemia, especially when combined with other diabetes medications or if you skip meals. Learn to recognize the symptoms of low blood sugar, such as shakiness, sweating, dizziness, confusion, and rapid heartbeat. Carry a source of quick-acting glucose, like glucose tablets or fruit juice, to treat episodes of hypoglycemia promptly. Inform your family and friends about how to assist you in case of a severe hypoglycemic event.
  • **Inform your doctor about other medications and health conditions:** Before starting GLUCORYL MP 2MG TABLET 15'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Also, disclose any existing health conditions, such as kidney or liver problems, heart disease, or allergies. This information will help your doctor assess the safety and suitability of the medication for you and minimize the risk of potential drug interactions or adverse effects.
  • **Stay hydrated and avoid excessive alcohol consumption:** Drink plenty of water throughout the day to maintain optimal hydration. Limit your alcohol intake, as alcohol can interfere with blood sugar control and increase the risk of hypoglycemia. If you choose to drink alcohol, do so in moderation and consume it with food. Discuss your alcohol consumption habits with your doctor to receive personalized advice.

Food Interactions with GLUCORYL MP 2MG TABLET 15'SArrow

  • It is advisable to take GLUCORYL MP 2MG TABLET 15'S with or immediately after your first main meal of the day to avoid hypoglycemia (low blood sugar).
  • Avoid skipping meals while taking this medication.
  • Be cautious about alcohol consumption, as it can increase the risk of hypoglycemia.

FAQs

What is Glucoryl MP 2mg Tablet used for?Arrow

Glucoryl MP 2mg Tablet is used to treat type 2 diabetes mellitus in adults when diet and exercise are not sufficient to control blood sugar levels. It is usually prescribed along with other antidiabetic medicines.

What are the common side effects of Glucoryl MP 2mg Tablet?Arrow

Common side effects include hypoglycemia (low blood sugar), nausea, diarrhea, stomach pain, and headache. It is important to consult your doctor if these side effects persist or worsen.

How should I store Glucoryl MP 2mg Tablet?Arrow

Store Glucoryl MP 2mg Tablet at room temperature, away from direct sunlight, heat, and moisture. Keep it out of the reach of children and pets.

Can I take Glucoryl MP 2mg Tablet if I am pregnant or breastfeeding?Arrow

It is generally not recommended to take Glucoryl MP 2mg Tablet during pregnancy or breastfeeding. Consult your doctor for advice on alternative treatments.

What should I do if I miss a dose of Glucoryl MP 2mg Tablet?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can Glucoryl MP 2mg Tablet cause hypoglycemia?Arrow

Yes, Glucoryl MP 2mg Tablet can cause hypoglycemia, especially if taken with other antidiabetic medications or if meals are skipped or delayed. Monitor your blood sugar levels regularly and follow your doctor's instructions.

Are there any specific dietary instructions while taking Glucoryl MP 2mg Tablet?Arrow

Follow a balanced diet with regular meal times. Avoid sugary foods and drinks. Consult a dietician for a personalized diet plan suitable for diabetes.

Can Glucoryl MP 2mg Tablet be used for type 1 diabetes?Arrow

No, Glucoryl MP 2mg Tablet is not used for type 1 diabetes. It is specifically indicated for type 2 diabetes mellitus.

What medications should I avoid while taking Glucoryl MP 2mg Tablet?Arrow

Inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements, as some medications may interact with Glucoryl MP 2mg Tablet. Specifically, avoid taking NSAIDs (like ibuprofen) without consulting your doctor.

How does Glucoryl MP 2mg Tablet work?Arrow

Glucoryl MP 2mg Tablet works by increasing the release of insulin from the pancreas and decreasing glucose production in the liver. It also improves the body's response to insulin.

Can I drink alcohol while taking Glucoryl MP 2mg Tablet?Arrow

It is recommended to avoid or limit alcohol consumption while taking Glucoryl MP 2mg Tablet as it can increase the risk of hypoglycemia and other side effects.

What should I do in case of an overdose of Glucoryl MP 2mg Tablet?Arrow

In case of an overdose, seek immediate medical attention. Symptoms of overdose may include severe hypoglycemia, nausea, vomiting, and loss of consciousness.

Can Glucoryl MP 2mg Tablet affect kidney function?Arrow

In patients with pre-existing kidney problems, Glucoryl MP 2mg Tablet may affect kidney function. Regular monitoring of kidney function is recommended in such patients. Consult your doctor if you have kidney disease.

Does Glucoryl MP 2mg Tablet interact with other drugs used for diabetes?Arrow

Yes, Glucoryl MP 2mg Tablet can interact with other antidiabetic medications. It is important to inform your doctor about all the medications you are taking to avoid potential drug interactions.

How long does it take for Glucoryl MP 2mg Tablet to show its effect?Arrow

The time it takes for Glucoryl MP 2mg Tablet to show its effect can vary from person to person. It usually takes a few days to weeks to see a noticeable improvement in blood sugar levels. Continue taking the medicine as prescribed by your doctor.

References

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DrugBank: Glimepiride (DB01060) - Comprehensive information on glimepiride, including its mechanism of action, pharmacokinetics, and interactions.

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FDA Label: Amaryl (glimepiride) tablets - Official FDA label information for glimepiride, providing details on indications, dosage, and safety.

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National Center for Biotechnology Information (NCBI): Efficacy and Safety of Glimepiride Plus Metformin vs. other hypoglycemic drugs in type 2 diabetes: A network meta-analysis - Research article comparing the efficacy and safety of glimepiride and metformin with other treatments for type 2 diabetes.

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ScienceDirect: Glimepiride - Overview of glimepiride, including its pharmacology and clinical applications.

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FDA: Pioglitazone HCL and Glimepiride - Information on Pioglitazone and Glimepiride combination

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ALKEM LABORATORIES LIMITED

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India

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