OZOMET PG 2MG TABLET 15'S

How OZOMET PG 2MG TABLET 15'S Works

• OZOMET PG 2MG TABLET 15'S is a combination medication designed to manage type 2 diabetes mellitus effectively. It contains three active ingredients: Ozempic (Semaglutide), Pioglitazone, and Metformin. Each component works through different mechanisms to lower blood glucose levels and improve overall glycemic control.
• **Semaglutide:** Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. It mimics the effects of natural GLP-1, a hormone released in the gut in response to food intake. Semaglutide enhances insulin secretion when blood glucose levels are high, thus helping to lower post-meal glucose spikes. It also suppresses glucagon secretion, a hormone that raises blood glucose levels. Furthermore, Semaglutide slows down gastric emptying, which reduces the rate at which glucose is absorbed from the intestine into the bloodstream. This can also contribute to a feeling of fullness, potentially aiding in weight management.
• **Pioglitazone:** Pioglitazone is a thiazolidinedione (TZD) that works by increasing the body's sensitivity to insulin. It activates peroxisome proliferator-activated receptor gamma (PPARγ), a receptor found in fat, muscle, and liver cells. Activation of PPARγ improves insulin sensitivity in these tissues, allowing them to use glucose more effectively. This reduces insulin resistance, a key factor in type 2 diabetes. Pioglitazone primarily reduces glucose production in the liver and increases glucose uptake and utilization in peripheral tissues.
• **Metformin:** Metformin is a biguanide that primarily works by reducing glucose production in the liver. It inhibits hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Metformin also enhances insulin sensitivity in peripheral tissues, similar to Pioglitazone, but through different mechanisms. It increases glucose uptake and utilization in muscle tissue. Additionally, Metformin slows down the absorption of glucose from the intestine, further contributing to its glucose-lowering effects. It is also known to improve lipid profiles and may have some beneficial effects on weight management.
• In combination, these three medications address multiple aspects of type 2 diabetes. Semaglutide helps regulate insulin and glucagon secretion and slows gastric emptying. Pioglitazone improves insulin sensitivity in fat, muscle, and liver tissues. Metformin reduces glucose production in the liver and enhances peripheral insulin sensitivity. By targeting different pathways, OZOMET PG 2MG TABLET 15'S provides comprehensive glycemic control, helping patients achieve and maintain target blood glucose levels and reduce the risk of diabetes-related complications. Regular monitoring and adherence to prescribed diet and exercise are crucial for optimal therapeutic outcomes.

OZOMET PG 2MG TABLET 15'S can cause several side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and metallic taste. Some patients might experience hypoglycemia (low blood sugar), which can cause symptoms like dizziness, sweating, confusion, and tremors. Less common side effects may involve skin rashes, itching, and allergic reactions. In rare cases, it can lead to more serious complications like liver problems or lactic acidosis (a buildup of lactic acid in the body). If you experience any persistent or severe side effects, it's crucial to consult your doctor.

• If you miss a dose of OZOMET PG 2MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep OZOMET PG 2MG TAB 1X15 away from the reach of children and pets.
• Store OZOMET PG 2MG TAB 1X15 at room temperature.

• OZOMET PG 2MG TABLET 15'S should be taken orally, preferably with meals to decrease the chance of stomach upset.
• Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of low blood sugar (hypoglycemia).
• There are no specific food restrictions but it's essential to maintain a consistent carbohydrate intake to help regulate blood sugar levels. Consult your doctor or dietician for personalized dietary advice tailored to your diabetes management plan.