AVANGIO 100MG/4ML INJECTION
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AVANGIO 100MG/4ML INJECTION
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AVANGIO 100MG/4ML INJECTION

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AVANGIO 100MG/4ML INJECTION

By PLASMAGEN BIOSCIENCES PVT LTD

MRP

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10181

₹7635.75

25 % OFF

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Product DetailsArrow

About AVANGIO 100MG/4ML INJECTION

  • AVANGIO 100MG/4ML INJECTION is an anticancer medication containing Bevacizumab as its active component. This medication is specifically designed to inhibit tumor growth. It's prescribed alongside other chemotherapy drugs for treating several cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It also finds application in treating cancers affecting the ovary, fallopian tube, or primary peritoneal region. During treatment with AVANGIO 100MG/4ML INJECTION and for a minimum of six months following the final dose, it's essential to use effective birth control methods. This medication is not suitable for adolescents and children under 18 years of age. If you're a woman planning for pregnancy in the future, discuss options for ovary preservation with your healthcare provider, as AVANGIO 100MG/4ML INJECTION can potentially lead to fertility problems in women. Furthermore, breastfeeding should be avoided while taking this medication, as it could negatively impact the baby's growth and development.
  • AVANGIO 100MG/4ML INJECTION is frequently used in combination with other chemotherapeutic agents to enhance its effectiveness in combating cancer. Common side effects associated with this medication include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. It's crucial to inform your doctor about any pre-existing medical conditions before starting treatment with AVANGIO 100MG/4ML INJECTION, particularly if you have a history of high blood pressure, high blood sugar, stomach disorders, or heart problems. To minimize the risk of poor wound healing and bleeding complications, avoid taking AVANGIO 100MG/4ML INJECTION for 28 days before and after any surgical procedures. If you require dental surgery, consult your doctor before commencing treatment with this medication. In case you experience any visual changes or confusion, promptly notify your doctor to prevent potential complications. Regular monitoring and open communication with your healthcare provider are essential for managing potential side effects and ensuring the safe and effective use of AVANGIO 100MG/4ML INJECTION. Be sure to maintain a healthy lifestyle and balanced diet to support your body during the treatment process.
  • Additionally, it's important to understand that AVANGIO 100MG/4ML INJECTION works by targeting a specific protein called vascular endothelial growth factor (VEGF), which plays a crucial role in the formation of new blood vessels that tumors need to grow. By blocking VEGF, the medicine helps to prevent the tumor from getting the nutrients it needs, thus slowing down or stopping its growth. Therefore, it's essential to adhere strictly to the prescribed dosage and schedule to ensure optimal results. Always consult your doctor or pharmacist if you have any concerns or questions about your treatment.

Uses of AVANGIO 100MG/4ML INJECTION

  • AVANGIO 100MG/4ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This is a type of aggressive brain tumor.
  • Persistent, recurrent, or metastatic breast cancer. This refers to breast cancer that keeps coming back or has spread to other parts of the body.
  • Metastatic cervical cancer. This indicates cervical cancer that has spread to distant sites in the body.
  • Advanced kidney cancer. This refers to kidney cancer that has progressed and may be difficult to treat.
  • Metastatic colorectal cancer. This is colorectal cancer that has spread to other parts of the body.
  • Advanced non-small-cell lung cancer. This indicates a more progressed stage of non-small-cell lung cancer.
  • Liver Cancer - Hepatocellular carcinoma. This is a type of cancer that originates in the liver cells.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. This covers cancers affecting the female reproductive organs and surrounding tissues.

Side Effects of AVANGIO 100MG/4ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects may include headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness, and shortness of breath. Common side effects may include numbness in hands or feet, weakness and lack of energy, diarrhoea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, and back pain.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for AVANGIO 100MG/4ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with AVANGIO 100MG/4ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of AVANGIO 100MG/4ML INJECTIONArrow

  • Your doctor or nurse will administer AVANGIO 100MG/4ML INJECTION through an intravenous infusion, a method where the medication is delivered directly into your vein over a specific period. This ensures the medication is absorbed effectively and starts working as intended. The infusion process will be closely monitored by healthcare professionals to observe your response and manage any potential side effects.
  • It's crucial to understand that the infusion should commence immediately after the AVANGIO 100MG/4ML INJECTION has been appropriately diluted. This is because the stability of the medication can be affected if it's left in a diluted state for an extended period. The healthcare provider will adhere to strict protocols to maintain the integrity and efficacy of the AVANGIO 100MG/4ML INJECTION throughout the administration process.
  • The dosage and duration of the infusion will be determined by your doctor, taking into account various factors such as your overall health, the condition being treated, and your response to the medication. Please do not hesitate to ask any questions you may have about the procedure or the medication itself. Your understanding and comfort are paramount during this process.

How to store AVANGIO 100MG/4ML INJECTION?Arrow

  • Keep AVANGIO 100MG INJ 4ML away from the reach of children and pets.
  • Store AVANGIO 100MG INJ 4ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of AVANGIO 100MG/4ML INJECTIONArrow

  • AVANGIO 100MG/4ML INJECTION is a targeted therapy medication designed to treat several types of advanced cancers. It is a recombinant humanized monoclonal antibody, meaning it's engineered to specifically recognize and bind to a particular protein in the body.
  • The drug's primary mechanism of action involves targeting vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein crucial for angiogenesis, the formation of new blood vessels. It is found in the lining of blood and lymph vessels. By binding to VEGF-A, AVANGIO 100MG/4ML INJECTION prevents it from interacting with its receptors.
  • This interaction is crucial for tumors to grow and spread. Tumors need a constant supply of oxygen and nutrients, which they obtain through the formation of new blood vessels. By blocking VEGF-A, AVANGIO 100MG/4ML INJECTION inhibits the formation of these new blood vessels, effectively cutting off the tumor's lifeline.
  • Consequently, the medication slows down the progression of cancer by limiting its ability to grow and spread. This targeted approach helps to manage the disease and potentially improve patient outcomes in certain advanced cancer cases. It works by disrupting the tumor's ability to establish its own blood supply, starving it of essential resources.

How to use AVANGIO 100MG/4ML INJECTIONArrow

  • AVANGIO 100MG/4ML INJECTION will be administered to you by your doctor or nurse through intravenous infusion. This means the medication is delivered directly into your vein over a specific period. The infusion process allows for controlled and consistent delivery of the drug into your bloodstream, ensuring optimal absorption and effectiveness. The healthcare professional will closely monitor you during the infusion for any potential side effects or complications.
  • It is crucial that the infusion begins immediately after the dilution of the AVANGIO 100MG/4ML INJECTION. This is because the diluted solution may not remain stable for an extended period, and delaying the infusion could compromise its potency or increase the risk of contamination. Your healthcare provider will prepare the medication according to strict guidelines to maintain its integrity and efficacy.
  • If you have any concerns or questions about the infusion process, do not hesitate to ask your doctor or nurse. They can provide detailed explanations and address any anxieties you may have. Understanding the procedure and potential side effects can help you feel more comfortable and confident during your treatment. Regular monitoring and communication with your healthcare team are essential for a successful outcome.

FAQs

Is AVANGIO 100MG/4ML INJECTION used as standalone treatment in cancers?Arrow

AVANGIO 100MG/4ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use AVANGIO 100MG/4ML INJECTION?Arrow

While for women with reproductive potential subjected to AVANGIO 100MG/4ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with AVANGIO 100MG/4ML INJECTION?Arrow

AVANGIO 100MG/4ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of AVANGIO 100MG/4ML INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by AVANGIO 100MG/4ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is AVANGIO 100MG/4ML INJECTION administered?Arrow

AVANGIO 100MG/4ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take AVANGIO 100MG/4ML INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with AVANGIO 100MG/4ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

NULL interaction of AVANGIO 100MG/4ML INJECTION with other drungsArrow

There are no known interactions of AVANGIO 100MG/4ML INJECTION with other drugs.

What conditions should I inform my doctor about before taking AVANGIO 100MG/4ML INJECTION?Arrow

It is vital to inform your physician before taking AVANGIO 100MG/4ML INJECTION if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to AVANGIO 100MG/4ML INJECTION or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

What molecule/combination is used for making AVANGIO 100MG/4ML INJECTION?Arrow

BEVACIZUMAB is molecule/combination used for making AVANGIO 100MG/4ML INJECTION.

For what ailments/diseases/conditions is AVANGIO 100MG/4ML INJECTION prescribed?Arrow

AVANGIO 100MG/4ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

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