AVASTIMAB 100MG INJECTION
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AVASTIMAB 100MG INJECTION
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AVASTIMAB 100MG INJECTION

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AVASTIMAB 100MG INJECTION

By RPG LIFE SCIENCES LIMITED

MRP

18200

₹11199

38.47 % OFF

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Product DetailsArrow

About AVASTIMAB 100MG INJECTION

  • AVASTIMAB 100MG INJECTION is an anticancer medication containing Bevacizumab as its active ingredient. This medication is designed to inhibit tumor growth and is often used alongside other chemotherapy drugs to treat various metastatic cancers, including breast, brain, cervical, kidney, lung, and colorectal cancers. It is also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer. During treatment with AVASTIMAB 100MG INJECTION and for at least six months after the last dose, it is crucial to use effective birth control methods. This medication is not recommended for adolescents and children under 18 years of age.
  • If you are a woman planning for pregnancy in the future, discuss options for ovary preservation with your doctor, as AVASTIMAB 100MG INJECTION may cause fertility problems. It is also advised to avoid breastfeeding while on this medication, as it could interfere with the baby's growth and development. This ensures the safety and well-being of both the mother and the child. AVASTIMAB 100MG INJECTION works by targeting specific proteins that promote blood vessel growth in tumors, thus slowing down or stopping tumor progression.
  • AVASTIMAB 100MG INJECTION is typically administered in combination with other chemotherapy agents. Common side effects include constipation, loss of appetite, runny nose, fever, skin issues, and weight loss. Before initiating treatment, inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems. This medication should not be taken for 28 days before or after surgery due to potential risks of poor wound healing and increased bleeding complications. It's important to consult your dentist before starting treatment if you require any dental procedures. Report any visual changes or confusion to your doctor immediately to prevent further complications.

Uses of AVASTIMAB 100MG INJECTION

  • AVASTIMAB 100MG INJECTION is indicated to treat the following conditions:
  • Glioblastoma multiforme (brain cancer)
  • Persistent, recurrent, or metastatic breast cancer
  • Metastatic cervical cancer
  • Advanced kidney cancer
  • Metastatic colorectal cancer
  • Advanced non-small-cell lung cancer
  • Liver Cancer- Hepatocellular carcinoma
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

Side Effects of AVASTIMAB 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects may include headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness and shortness of breath. Common side effects include numbness in hands or feet, weakness and lack of energy, diarrhoea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin and back pain.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for AVASTIMAB 100MG INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with AVASTIMAB 100MG INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of AVASTIMAB 100MG INJECTIONArrow

  • AVASTIMAB 100MG INJECTION will be administered to you by a qualified healthcare professional, such as your physician or nurse, via intravenous infusion. This means the medication will be delivered directly into your vein over a period of time. The typical administration involves diluting the AVASTIMAB 100MG INJECTION solution and then slowly infusing it into your bloodstream. The infusion process will be closely monitored by your healthcare provider to ensure your safety and comfort. Please inform your doctor immediately if you feel unwell.
  • It's crucial that the AVASTIMAB 100MG INJECTION infusion begins promptly after the solution has been properly diluted. This is because the stability of the diluted medication may decrease over time. Your healthcare team is trained to adhere to this guideline to ensure you receive the most effective dose. The exact duration of the infusion may vary based on your individual needs and tolerance, but your medical team will carefully manage the process.
  • During the infusion, your vital signs, such as blood pressure, heart rate, and breathing, will be regularly monitored. This allows the healthcare team to detect and manage any potential side effects promptly. If you have any concerns or experience any unusual symptoms during the infusion, don't hesitate to inform your nurse or physician immediately.

How to store AVASTIMAB 100MG INJECTION?Arrow

  • Keep AVASTIMAB 100MG INJ away from the reach of children and pets.
  • Store AVASTIMAB 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of AVASTIMAB 100MG INJECTIONArrow

  • AVASTIMAB 100MG INJECTION is a targeted therapy medication utilized in the management of several advanced cancers. It functions as a recombinant humanized monoclonal antibody. This means it's a laboratory-created protein designed to specifically target a particular substance in the body.
  • The mechanism of action of AVASTIMAB 100MG INJECTION revolves around its selective binding to vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein present on the inner lining of blood and lymph vessels. By binding to VEGF-A, the medication disrupts its interaction with its receptors.
  • This disruption is crucial because VEGF-A plays a vital role in angiogenesis, the formation of new blood vessels. Tumors require a constant supply of oxygen and nutrients to grow and spread. They stimulate angiogenesis to create these new blood vessels. AVASTIMAB 100MG INJECTION, by inhibiting VEGF-A, effectively cuts off the tumor's supply line.
  • The ultimate result of this action is a slowing down of cancer progression. By preventing the formation of new blood vessels, AVASTIMAB 100MG INJECTION deprives the tumor of the resources it needs to grow and spread, thereby controlling the advancement of the disease.

How to use AVASTIMAB 100MG INJECTIONArrow

  • AVASTIMAB 100MG INJECTION will be administered to you by your doctor or nurse through an intravenous (IV) infusion, a method where the medication is delivered directly into your vein. This ensures the drug is quickly and effectively absorbed into your system. The process involves a healthcare professional carefully inserting a small needle into a vein, typically in your arm, and connecting it to a bag containing the diluted AVASTIMAB 100MG INJECTION solution.
  • It is crucial that the infusion begins immediately after the AVASTIMAB 100MG INJECTION has been properly diluted. This is because the stability of the drug can be affected over time once it's mixed with the solution. Prompt administration ensures you receive the full therapeutic benefit of the medication.
  • The healthcare provider will closely monitor you during the infusion for any signs of an allergic reaction or other adverse effects. The infusion rate will be carefully controlled to minimize any potential discomfort or complications. If you experience any unusual symptoms, such as itching, rash, difficulty breathing, or swelling, inform your doctor or nurse immediately.
  • The duration of the infusion can vary depending on the specific treatment protocol and your individual response to the medication. Your doctor will determine the appropriate course of treatment based on your condition and other factors.

FAQs

Is AVASTIMAB 100MG INJECTION used as standalone treatment in cancers?Arrow

AVASTIMAB 100MG INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use AVASTIMAB 100MG INJECTION?Arrow

While for women with reproductive potential subjected to AVASTIMAB 100MG INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with AVASTIMAB 100MG INJECTION?Arrow

AVASTIMAB 100MG INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of AVASTIMAB 100MG INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by AVASTIMAB 100MG INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is AVASTIMAB 100MG INJECTION administered?Arrow

AVASTIMAB 100MG INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take AVASTIMAB 100MG INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with AVASTIMAB 100MG INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Is there any interaction of AVASTIMAB 100MG INJECTION with other drugs?Arrow

There is no specific information available regarding the interaction of AVASTIMAB 100MG INJECTION with other drugs.

What conditions should I inform my doctor about before taking AVASTIMAB 100MG INJECTION?Arrow

It is vital to inform your physician before taking AVASTIMAB 100MG INJECTION if you have the following conditions: * Have conditions involving inflammation in the stomach (ulcer, colitis). * Experience allergic reactions to AVASTIMAB 100MG INJECTION or its ingredients. * Have recently undergone surgery as it is associated with the risk of bleeding. * Have diabetes, hypertension, or heart problems.

What is Bevacizumab and how is it used to make AVASTIMAB 100MG INJECTION?Arrow

Bevacizumab is the molecule used for making AVASTIMAB 100MG INJECTION. It is the active ingredient of the medication, meaning it is the component that produces the therapeutic effect.

For which ailments/diseases/conditions in Oncology is AVASTIMAB 100MG INJECTION prescribed?Arrow

AVASTIMAB 100MG INJECTION is used to treat a variety of Oncology diseases. This medication helps to prevent the growth and spread of cancer cells.

How does AVASTIMAB 100MG INJECTION work in Oncology?Arrow

AVASTIMAB 100MG INJECTION works in Oncology by blocking the growth of blood vessels that feed tumors. This helps to slow down or shrink the tumor's growth.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

RPG LIFE SCIENCES LIMITED

Country of Origin -

India

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MRP

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₹11199

38.47 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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