ZYBEV 100 INJECTION 4 ML
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ZYBEV 100 INJECTION 4 ML
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ZYBEV 100 INJECTION 4 ML

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ZYBEV 100 INJECTION 4 ML

By ZYDUS LIFESCIENCES LIMITED

MRP

19200

₹15360

20 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About ZYBEV 100 INJECTION 4 ML

  • ZYBEV 100 INJECTION 4 ML is an anticancer medication containing Bevacizumab as its active component. It works by preventing tumor growth and is used alongside other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It is also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer. Women of childbearing potential should use effective birth control during treatment and for at least six months after the final dose.
  • ZYBEV 100 INJECTION 4 ML is not recommended for children and adolescents under 18 years old. If you are planning to become pregnant, discuss ovarian preservation with your doctor, as this medication may affect fertility in women. Breastfeeding should be avoided while using this medicine due to potential risks to the baby's growth and development. It's crucial to inform your healthcare provider about all existing medical conditions and medications you are taking.
  • This injection is often given in combination with other chemotherapy drugs. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. Inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment. Avoid taking ZYBEV 100 INJECTION 4 ML for 28 days before and after surgery due to risks of impaired wound healing and increased bleeding. Report any dental issues requiring surgery to your doctor before treatment. Promptly report any visual changes or confusion to your doctor to prevent complications.

Uses of ZYBEV 100 INJECTION 4 ML

  • ZYBEV 100 INJECTION 4 ML is indicated to treat the following conditions:
  • Glioblastoma multiforme (brain cancer)
  • Persistent, recurrent, or metastatic breast cancer
  • Metastatic cervical cancer
  • Advanced kidney cancer
  • Metastatic colorectal cancer
  • Advanced non-small-cell lung cancer
  • Liver Cancer- Hepatocellular carcinoma
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

Side Effects of ZYBEV 100 INJECTION 4 MLArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects may include headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness and shortness of breath. Common side effects may include numbness in hands or feet, weakness and lack of energy, diarrhoea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin and back pain.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for ZYBEV 100 INJECTION 4 MLArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with ZYBEV 100 INJECTION 4 ML in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of ZYBEV 100 INJECTION 4 MLArrow

  • ZYBEV 100 INJECTION 4 ML will be administered to you by a healthcare professional, such as a physician or nurse, via intravenous infusion. This means the medication will be delivered directly into your vein through a small tube.
  • The ZYBEV 100 INJECTION 4 ML infusion will be administered immediately after it has been properly diluted. This dilution process is crucial to ensure the medication is delivered safely and effectively.
  • The dosage and duration of the ZYBEV 100 INJECTION 4 ML infusion will depend on your individual medical condition, the severity of your illness, and your response to the treatment. Your doctor will determine the most appropriate dosage schedule for you.
  • It is important to closely follow your doctor's instructions regarding the ZYBEV 100 INJECTION 4 ML infusion. Do not attempt to self-administer the medication or alter the dosage without consulting your healthcare provider. If you have any questions or concerns about the infusion process, do not hesitate to ask your doctor or nurse for clarification.

How to store ZYBEV 100 INJECTION 4 ML?Arrow

  • Keep ZYBEV 100MG INJ away from the reach of children and pets.
  • Store ZYBEV 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ZYBEV 100 INJECTION 4 MLArrow

  • ZYBEV 100 INJECTION 4 ML is a targeted therapy designed to combat various advanced cancers. It functions as a recombinant humanized monoclonal antibody, meaning it's a lab-created protein engineered to specifically target and bind to a particular substance in the body.
  • The injection's primary target is vascular endothelial growth factor A (VEGF-A), a protein found on the inner lining of blood and lymph vessels. VEGF-A plays a crucial role in angiogenesis, the formation of new blood vessels.
  • By selectively binding to VEGF-A, ZYBEV 100 INJECTION 4 ML disrupts VEGF-A's ability to interact with its receptors. This interaction is essential for signaling the growth of new blood vessels.
  • Inhibiting the VEGF-A and receptor interaction effectively cuts off the supply line to the tumor. Cancer cells require a constant supply of oxygen and nutrients to proliferate and spread. By blocking angiogenesis, ZYBEV 100 INJECTION 4 ML deprives the tumor of these vital resources.
  • Ultimately, this action slows down the progression of the cancer. It doesn't directly kill the cancer cells, but it inhibits their ability to grow and metastasize, offering a valuable tool in managing the disease.

How to use ZYBEV 100 INJECTION 4 MLArrow

  • ZYBEV 100 INJECTION 4 ML will be administered to you by your doctor or nurse through an intravenous infusion. This means the medication will be delivered directly into your vein over a specific period. The infusion will be given immediately after the solution has been properly diluted to ensure its stability and effectiveness.
  • The healthcare professional administering ZYBEV 100 INJECTION 4 ML will closely monitor you during the infusion for any signs of adverse reactions. It is crucial to inform them immediately if you experience any discomfort, such as itching, rash, difficulty breathing, or swelling.
  • The dosage and duration of ZYBEV 100 INJECTION 4 ML treatment will be determined by your doctor based on your specific medical condition and response to the medication. Following the doctor's instructions regarding the treatment plan is essential for optimal results.
  • Before receiving ZYBEV 100 INJECTION 4 ML, make sure to inform your doctor about any existing medical conditions you have, especially heart problems, lung problems, or allergies. Also, inform them about any other medications you are currently taking, including over-the-counter drugs and herbal supplements.
  • If you have any concerns or questions about ZYBEV 100 INJECTION 4 ML, do not hesitate to ask your doctor or nurse. They are the best source of information regarding your treatment and can address any doubts you may have.

FAQs

1. Is ZYBEV 100 INJECTION 4 ML used as standalone treatment in cancers?Arrow

ZYBEV 100 INJECTION 4 ML is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

2. Is it safe for women to use ZYBEV 100 INJECTION 4 ML?Arrow

While for women with reproductive potential subjected to ZYBEV 100 INJECTION 4 ML, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

3. Is it safe to undergo a surgery during the treatment with ZYBEV 100 INJECTION 4 ML?Arrow

ZYBEV 100 INJECTION 4 ML is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

4. Do the side effects of ZYBEV 100 INJECTION 4 ML last for a chronic period?Arrow

All the side effects that are relatively caused by ZYBEV 100 INJECTION 4 ML occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

5. How is ZYBEV 100 INJECTION 4 ML administered?Arrow

ZYBEV 100 INJECTION 4 ML is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

6. Can I take ZYBEV 100 INJECTION 4 ML if I am pregnant?Arrow

Inform your physician before starting your treatment with ZYBEV 100 INJECTION 4 ML in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

NULL interaction of ZYBEV 100 INJECTION 4 ML with other drungsArrow

There is no known interaction of ZYBEV 100 INJECTION 4 ML with other drugs.

When should I inform my doctor before taking ZYBEV 100 INJECTION 4 ML?Arrow

It is vital to inform your physician before taking ZYBEV 100 INJECTION 4 ML if you have conditions involving inflammation in the stomach (ulcer, colitis), experience allergic reactions to ZYBEV 100 INJECTION 4 ML or its ingredients, have recently undergone surgery as it is associated with the risk of bleeding, or have diabetes, hypertension, or heart problems.

What molecule/combination is used for making ZYBEV 100 INJECTION 4 ML?Arrow

BEVACIZUMAB is used for making ZYBEV 100 INJECTION 4 ML.

For what ailments/diseases/conditions is ZYBEV 100 INJECTION 4 ML prescribed?Arrow

ZYBEV 100 INJECTION 4 ML is prescribed for ailments/diseases/conditions related to Oncology.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Reviewed on 10-02-2024

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(5/5)


Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

Country of Origin -

India

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MRP

19200

₹15360

20 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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