CIZUMAB 100 INJECTION
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CIZUMAB 100 INJECTION
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CIZUMAB 100 INJECTION

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CIZUMAB 100 INJECTION

By HETERO HEALTHCARE LTD

MRP

14300

₹7222

49.5 % OFF

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Product DetailsArrow

About CIZUMAB 100 INJECTION

  • CIZUMAB 100 INJECTION is an anticancer medicine containing Bevacizumab as its active ingredient. It is designed to inhibit tumor growth and is used alongside other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, colorectal cancer, and cancers of the ovary, fallopian tube, or primary peritoneal cancer. It is crucial to use effective birth control during treatment and for at least six months following the final dose of CIZUMAB 100 INJECTION. This medication is not recommended for adolescents and children under 18 years of age.
  • If you are planning to become pregnant in the future, discuss options for preserving your ovaries with your doctor, as this medicine may impair fertility in women. Breastfeeding is also not advised while taking CIZUMAB 100 INJECTION, as it may negatively impact the baby's growth and development. CIZUMAB 100 INJECTION is often administered in conjunction with other chemotherapy drugs to achieve optimal results.
  • Common side effects associated with CIZUMAB 100 INJECTION include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. Inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before commencing treatment with this medicine. Avoid taking CIZUMAB 100 INJECTION for 28 days before and after surgery due to the increased risk of poor wound healing and bleeding complications. It's also important to address any dental issues requiring surgery before starting this medication.
  • Report any visual changes or confusion to your doctor immediately to prevent potential complications. Regular monitoring and communication with your healthcare provider are essential throughout the treatment period to manage side effects and ensure the best possible outcome.

Uses of CIZUMAB 100 INJECTION

  • CIZUMAB 100 INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). Glioblastoma multiforme is an aggressive type of cancer that occurs in the brain or spinal cord. CIZUMAB 100 INJECTION helps in reducing the growth of the cancer cells.
  • Persistent, recurrent, or metastatic breast cancer. CIZUMAB 100 INJECTION can be used in cases where breast cancer has spread to other parts of the body or keeps coming back despite treatment. This helps to target the growing cancer.
  • Metastatic cervical cancer. When cervical cancer spreads to distant organs, CIZUMAB 100 INJECTION can be employed to slow down the spread and manage the symptoms, improving overall prognosis and survival rate.
  • Advanced kidney cancer. In cases where kidney cancer has progressed, CIZUMAB 100 INJECTION can target the factors that contribute to cancer growth, offering a chance to control the disease progression.
  • Metastatic colorectal cancer. CIZUMAB 100 INJECTION is useful when colorectal cancer has spread to other areas. It can help to inhibit the development of new blood vessels that feed the tumor.
  • Advanced non-small-cell lung cancer. For advanced stages of non-small-cell lung cancer, CIZUMAB 100 INJECTION can be part of a treatment plan to reduce tumor size and improve patient outcomes, thus improving overall quality of life.
  • Liver Cancer- Hepatocellular carcinoma. CIZUMAB 100 INJECTION may be an option for treating hepatocellular carcinoma, a type of liver cancer. It works by targeting specific pathways involved in cancer cell growth.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. CIZUMAB 100 INJECTION can be considered in the treatment of cancers affecting the female reproductive system, aiming to slow disease progression and extend survival. The injection helps in preventing the cancer cells from growing further.

Side Effects of CIZUMAB 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects include headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores and dryness, and shortness of breath. Common side effects include numbness in hands or feet, weakness and lack of energy, diarrhea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, and back pain.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for CIZUMAB 100 INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with CIZUMAB 100 INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of CIZUMAB 100 INJECTIONArrow

  • CIZUMAB 100 INJECTION will be administered by your doctor or nurse through an intravenous infusion. This means the medication is delivered directly into your vein over a period of time.
  • The healthcare professional will carefully dilute the CIZUMAB 100 INJECTION before administration. This dilution process is essential to ensure the medication is delivered safely and effectively.
  • It is crucial that the infusion begins immediately after the dilution process is complete. This helps maintain the stability and efficacy of the drug. Your medical team will closely monitor you throughout the infusion to watch for any potential side effects and ensure your comfort.
  • The dosage and duration of the infusion will be determined by your doctor based on your specific medical condition and response to treatment. Do not hesitate to ask your doctor or nurse any questions you may have about the procedure.

How to store CIZUMAB 100 INJECTION?Arrow

  • Keep CIZUMAB 100MG INJ away from the reach of children and pets.
  • Store CIZUMAB 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of CIZUMAB 100 INJECTIONArrow

  • CIZUMAB 100 INJECTION is a targeted therapy designed to combat advanced cancers. As a recombinant humanized monoclonal antibody, it zeroes in on a specific protein known as vascular endothelial growth factor A (VEGF-A). This protein resides in the inner lining of blood and lymph vessels.
  • The injection's mechanism of action involves selectively binding to VEGF-A, thereby disrupting its ability to interact with its receptors. This disruption is crucial because VEGF-A plays a pivotal role in angiogenesis, the formation of new blood vessels. By blocking this interaction, the injection effectively cuts off the tumor's lifeline.
  • Tumors require a constant supply of oxygen and nutrients to grow and spread. These are delivered through a network of blood vessels created by VEGF-A. CIZUMAB 100 INJECTION, by inhibiting VEGF-A, prevents the formation of new blood vessels that feed the tumor. This action slows down the tumor's growth rate and its ability to metastasize, offering a significant advantage in cancer treatment.
  • By targeting VEGF-A, this medication works differently than traditional chemotherapy, potentially leading to a different side effect profile and allowing for a more targeted approach to cancer treatment. This targeted approach aims to maximize efficacy while minimizing harm to healthy cells.

How to use CIZUMAB 100 INJECTIONArrow

  • CIZUMAB 100 INJECTION will be administered to you by your doctor or nurse as an intravenous infusion. This means the medication will be delivered directly into your vein through a small tube. The healthcare professional will carefully monitor you during the infusion process to watch for any potential reactions or complications.
  • The infusion should begin immediately after the CIZUMAB 100 INJECTION has been properly diluted. Dilution is a crucial step that ensures the medication is at the correct concentration for safe and effective administration. Your doctor or nurse will use a sterile solution to dilute the CIZUMAB 100 INJECTION before starting the infusion.
  • The length of the infusion can vary, but your healthcare provider will determine the appropriate duration based on your individual needs and response to the medication. It is important to remain comfortable and inform your nurse immediately if you experience any discomfort, pain, or unusual symptoms during the infusion. Following your doctor’s instructions and completing the full course of treatment is essential for optimal results.

FAQs

Is CIZUMAB 100 INJECTION used as standalone treatment in cancers?Arrow

CIZUMAB 100 INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use CIZUMAB 100 INJECTION?Arrow

While for women with reproductive potential subjected to CIZUMAB 100 INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with CIZUMAB 100 INJECTION?Arrow

CIZUMAB 100 INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of CIZUMAB 100 INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by CIZUMAB 100 INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is CIZUMAB 100 INJECTION administered?Arrow

CIZUMAB 100 INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take CIZUMAB 100 INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with CIZUMAB 100 INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Is there any interaction of CIZUMAB 100 INJECTION with other drugs?Arrow

There is NULL interaction of CIZUMAB 100 INJECTION with other drugs

What conditions should I inform my doctor about before taking CIZUMAB 100 INJECTION?Arrow

It is vital to inform your physician before taking CIZUMAB 100 INJECTION if you have the following conditions: * Have conditions involving inflammation in the stomach (ulcer, colitis). * Experience allergic reactions to CIZUMAB 100 INJECTION or its ingredients. * Have recently undergone surgery as it is associated with the risk of bleeding. * Have diabetes, hypertension, or heart problems.

What is Bevacizumab and why is it used in CIZUMAB 100 INJECTION?Arrow

BEVACIZUMAB is a molecule used for making CIZUMAB 100 INJECTION.

For what ailments/diseases/conditions is CIZUMAB 100 INJECTION prescribed?Arrow

CIZUMAB 100 INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

HETERO HEALTHCARE LTD

Country of Origin -

India

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MRP

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49.5 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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