VEGFXTA 100 INJECTION
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VEGFXTA 100 INJECTION
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VEGFXTA 100 INJECTION

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VEGFXTA 100 INJECTION

By FRESENIUS KABI INDIA PVT LTD

MRP

13026.09

₹8965

31.18 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About VEGFXTA 100 INJECTION

  • VEGFXTA 100 INJECTION contains Bevacizumab as an active ingredient, a medication designed to inhibit tumor growth. It is used alongside other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, colorectal cancer, and cancers of the ovary, fallopian tube, or primary peritoneal cancer. If you are a woman of childbearing age, it is important to use effective birth control during treatment and for at least six months after the last dose to prevent potential harm to a developing fetus.
  • VEGFXTA 100 INJECTION is not recommended for use in adolescents and children under 18 years old. If you are planning for pregnancy in the future, discuss with your doctor about the preservation of your ovaries, as this medication may cause fertility issues in women. It is also advisable to avoid breastfeeding while using this medicine, as it could interfere with the baby's growth and development. Bevacizumab functions by targeting and blocking a protein called vascular endothelial growth factor (VEGF). VEGF plays a crucial role in angiogenesis, the formation of new blood vessels that tumors need to grow and spread. By inhibiting VEGF, Bevacizumab helps to prevent the tumor from developing its own blood supply, effectively slowing down its growth and spread to other parts of the body.
  • VEGFXTA 100 INJECTION is frequently used in combination with other chemotherapy agents. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. Inform your doctor about any existing medical conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment. This medication should not be taken for 28 days before and after surgery due to the risk of poor wound healing and bleeding complications. Report any dental issues requiring surgery to your doctor before starting VEGFXTA 100 INJECTION treatment. If you experience visual changes or confusion, promptly inform your doctor to prevent potential complications.

Uses of VEGFXTA 100 INJECTION

  • VEGFXTA 100 INJECTION is indicated to treat the following conditions:
  • Glioblastoma multiforme (brain cancer)
  • Persistent, recurrent, or metastatic breast cancer
  • Metastatic cervical cancer
  • Advanced kidney cancer
  • Metastatic colorectal cancer
  • Advanced non-small-cell lung cancer
  • Liver Cancer- Hepatocellular carcinoma
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

Side Effects of VEGFXTA 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for VEGFXTA 100 INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with VEGFXTA 100 INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of VEGFXTA 100 INJECTIONArrow

  • VEGFXTA 100 INJECTION is administered by a trained healthcare professional, such as your physician or nurse, via intravenous infusion. This means the medication is delivered directly into your vein over a specific period.
  • The infusion process will be closely monitored to ensure your safety and comfort. It's crucial that the infusion begins promptly after the VEGFXTA 100 INJECTION has been properly diluted to maintain its stability and effectiveness.
  • The healthcare provider will follow strict protocols for dilution and administration, adhering to the recommended guidelines. If you have any questions or concerns about the infusion process, don't hesitate to ask your doctor or nurse. They can provide you with detailed information and address any anxieties you may have.

How to store VEGFXTA 100 INJECTION?Arrow

  • Keep VEGFXTA 100MG INJ away from the reach of children and pets.
  • Store VEGFXTA 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of VEGFXTA 100 INJECTIONArrow

  • VEGFXTA 100 INJECTION is a targeted therapy designed to treat various advanced cancers by disrupting the formation of new blood vessels that feed tumors. It contains a recombinant humanized monoclonal antibody that specifically targets vascular endothelial growth factor A (VEGF-A).
  • VEGF-A is a protein found in the lining of blood and lymph vessels, and it plays a crucial role in angiogenesis, the process of new blood vessel formation. By binding to VEGF-A, VEGFXTA 100 INJECTION prevents it from interacting with its receptors on endothelial cells, effectively blocking the signaling pathways that stimulate angiogenesis.
  • This inhibition of angiogenesis is key to slowing down cancer progression. Tumors require a constant supply of oxygen and nutrients to grow and metastasize. By cutting off this supply, VEGFXTA 100 INJECTION helps to shrink tumors and prevent them from spreading to other parts of the body. This makes it a valuable tool in the fight against advanced cancers where uncontrolled growth and spread are major concerns.

How to use VEGFXTA 100 INJECTIONArrow

  • VEGFXTA 100 INJECTION is administered by your doctor or nurse through an intravenous infusion, ensuring precise and controlled delivery. This medication is never self-administered. The infusion process typically takes a specific amount of time, depending on the dosage and your individual needs, which will be determined by your healthcare provider. Before the infusion begins, the VEGFXTA 100 INJECTION will be carefully diluted by a healthcare professional to achieve the correct concentration for safe and effective administration. It's crucial that the diluted solution is used immediately to maintain its stability and efficacy. Your vital signs, such as blood pressure and heart rate, will be closely monitored throughout the infusion to detect any potential adverse reactions promptly.
  • It is important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking before receiving VEGFXTA 100 INJECTION. This will help them tailor the treatment plan to your specific needs and minimize the risk of any complications. If you experience any discomfort or unusual symptoms during the infusion, such as chills, fever, or difficulty breathing, notify your healthcare provider immediately. They will take appropriate measures to manage the situation and ensure your safety and well-being.
  • Remember, consistent communication with your healthcare team is key to a successful treatment journey with VEGFXTA 100 INJECTION. Follow their instructions carefully and attend all scheduled appointments to maximize the benefits of the medication and minimize any potential risks. Do not hesitate to ask any questions or express any concerns you may have.

FAQs

Is VEGFXTA 100 INJECTION used as standalone treatment in cancers?Arrow

VEGFXTA 100 INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use VEGFXTA 100 INJECTION?Arrow

While for women with reproductive potential subjected to VEGFXTA 100 INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with VEGFXTA 100 INJECTION?Arrow

VEGFXTA 100 INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of VEGFXTA 100 INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by VEGFXTA 100 INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is VEGFXTA 100 INJECTION administered?Arrow

VEGFXTA 100 INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take VEGFXTA 100 INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with VEGFXTA 100 INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Does VEGFXTA 100 INJECTION interact with other drugs?Arrow

There is no known interaction of VEGFXTA 100 INJECTION with other drugs.

What conditions should I inform my doctor about before taking VEGFXTA 100 INJECTION?Arrow

It is vital to inform your physician before taking VEGFXTA 100 INJECTION if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to VEGFXTA 100 INJECTION or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

What molecule/combination is used for making VEGFXTA 100 INJECTION?Arrow

BEVACIZUMAB is molecule/combination used for making VEGFXTA 100 INJECTION.

For which Oncology conditions is VEGFXTA 100 INJECTION used?Arrow

VEGFXTA 100 INJECTION is used to treat various Oncology conditions.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

FRESENIUS KABI INDIA PVT LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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