SYNDYMA 100MG/4ML INJECTION
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SYNDYMA 100MG/4ML INJECTION
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SYNDYMA 100MG/4ML INJECTION

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SYNDYMA 100MG/4ML INJECTION

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

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32250

₹24755

23.24 % OFF

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Product DetailsArrow

About SYNDYMA 100MG/4ML INJECTION

  • SYNDYMA 100MG/4ML INJECTION is an anticancer medication containing Bevacizumab as its active component. It works by inhibiting tumor growth and is often used alongside other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It's also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer. If you're a woman of childbearing age, it's crucial to use effective contraception during treatment and for at least six months after your last dose.
  • This medication is not recommended for children and adolescents under 18 years old. If you are planning to have children in the future, discuss options for preserving your ovaries with your doctor, as SYNDYMA 100MG/4ML INJECTION can potentially cause fertility issues in women. Breastfeeding is also not advised while using this medicine, as it may negatively affect the baby's development.
  • SYNDYMA 100MG/4ML INJECTION is commonly administered with other chemotherapy agents. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. Before starting treatment, inform your doctor if you have any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems. Avoid taking this medicine for 28 days before and after any surgery due to the risk of impaired wound healing and increased bleeding complications. Report any dental issues requiring surgery to your doctor before starting treatment.
  • It is important to immediately inform your doctor if you experience any visual changes or confusion while on SYNDYMA 100MG/4ML INJECTION to prevent potential complications. Your doctor will monitor you closely for any adverse effects and adjust your treatment plan as needed. Regular check-ups and open communication with your healthcare team are essential for ensuring the safe and effective use of this medication. Staying hydrated and maintaining a healthy diet can also help manage some of the common side effects associated with chemotherapy.

Uses of SYNDYMA 100MG/4ML INJECTION

  • SYNDYMA 100MG/4ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This aggressive form of brain cancer can be targeted with this medication, potentially slowing its growth and spread.
  • Persistent, recurrent, or metastatic breast cancer. For breast cancer that has returned, spread, or is resistant to other treatments, SYNDYMA 100MG/4ML INJECTION may offer another therapeutic option.
  • Metastatic cervical cancer. When cervical cancer spreads to other parts of the body, SYNDYMA 100MG/4ML INJECTION can be used as part of a treatment plan to manage the disease.
  • Advanced kidney cancer. In cases of advanced renal cell carcinoma, this injection can be utilized to combat the proliferation of cancerous cells within the kidneys.
  • Metastatic colorectal cancer. This medication can be part of a treatment regimen for colorectal cancer that has metastasized to distant sites in the body, aiding in controlling tumor growth.
  • Advanced non-small-cell lung cancer. For patients with advanced stages of non-small-cell lung cancer, SYNDYMA 100MG/4ML INJECTION can be used to slow down disease progression.
  • Liver Cancer- Hepatocellular carcinoma. SYNDYMA 100MG/4ML INJECTION may be considered in the treatment of hepatocellular carcinoma, a common type of liver cancer.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. SYNDYMA 100MG/4ML INJECTION can be used in the treatment of cancers originating in the female reproductive organs, including ovarian, cervical, and fallopian tube cancers, as well as primary peritoneal cancer.

Side Effects of SYNDYMA 100MG/4ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Therefore, it's important to be aware of potential issues. SYNDYMA 100MG/4ML INJECTION can cause both serious and common side effects.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for SYNDYMA 100MG/4ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with SYNDYMA 100MG/4ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of SYNDYMA 100MG/4ML INJECTIONArrow

  • SYNDYMA 100MG/4ML INJECTION will be administered to you by a doctor or nurse through an intravenous (IV) infusion, ensuring a controlled and safe delivery directly into your bloodstream. This method allows for precise dosage and rapid absorption of the medication.
  • The infusion process involves diluting SYNDYMA 100MG/4ML INJECTION in a suitable solution before administration. This dilution step is crucial to ensure the medication is delivered at the appropriate concentration and minimizes potential irritation to the veins.
  • It is imperative that the diluted SYNDYMA 100MG/4ML INJECTION be administered immediately after preparation. This is because the stability of the diluted solution may decrease over time, potentially affecting the drug's efficacy and safety. Your healthcare provider will carefully monitor the infusion process to ensure it is administered correctly and that you experience minimal discomfort. The duration of the infusion will be determined by your doctor, considering factors such as your condition and tolerance to the medication. If you have any concerns or experience any unusual symptoms during the infusion, inform your healthcare provider immediately.

How to store SYNDYMA 100MG/4ML INJECTION?Arrow

  • Keep SYNDYMA 100MG INJ away from the reach of children and pets.
  • Store SYNDYMA 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of SYNDYMA 100MG/4ML INJECTIONArrow

  • SYNDYMA 100MG/4ML INJECTION is a targeted therapy medication used to treat several types of advanced cancers. It contains a recombinant humanized monoclonal antibody that specifically targets and binds to vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein found in the lining of blood and lymph vessels.
  • By binding to VEGF-A, SYNDYMA 100MG/4ML INJECTION disrupts the interaction between VEGF-A and its receptors. This is crucial because VEGF-A plays a key role in angiogenesis, the formation of new blood vessels. Tumors need a constant supply of oxygen and nutrients to grow and spread, and they achieve this by stimulating angiogenesis.
  • By inhibiting the interaction of VEGF-A with its receptors, SYNDYMA 100MG/4ML INJECTION effectively blocks the formation of new blood vessels that feed the tumor. This process deprives the tumor of the resources it needs to grow, thereby slowing down the progression of the cancer and potentially improving outcomes for patients with advanced malignancies.

How to use SYNDYMA 100MG/4ML INJECTIONArrow

  • SYNDYMA 100MG/4ML INJECTION will be administered to you by a qualified healthcare professional, such as a physician or nurse, through intravenous infusion. This means the medication will be delivered directly into your vein over a specific period.
  • The injection will be prepared by diluting SYNDYMA 100MG/4ML INJECTION with a suitable solution to ensure it's safe and effective for intravenous administration. This dilution process is crucial for proper dosage and to minimize any potential discomfort or adverse reactions.
  • It's important to note that the intravenous infusion should commence immediately after the dilution process. This is to maintain the stability and efficacy of the medication, ensuring you receive the full therapeutic benefit. Your healthcare provider will closely monitor you during the infusion to watch out for any signs of discomfort or adverse reactions.
  • If you have any concerns or questions regarding the administration of SYNDYMA 100MG/4ML INJECTION, please do not hesitate to discuss them with your doctor or nurse. They are the best resource to address your individual needs and provide reassurance throughout the treatment process.

FAQs

<strong>Is SYNDYMA 100MG/4ML INJECTION used as standalone treatment in cancers?</strong>Arrow

SYNDYMA 100MG/4ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

<strong>Is it safe for women to use SYNDYMA 100MG/4ML INJECTION?</strong>Arrow

While for women with reproductive potential subjected to SYNDYMA 100MG/4ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

<strong>Is it safe to undergo a surgery during the treatment with SYNDYMA 100MG/4ML INJECTION?</strong>Arrow

SYNDYMA 100MG/4ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

<strong>Do the side effects of SYNDYMA 100MG/4ML INJECTION last for a chronic period?</strong>Arrow

All the side effects that are relatively caused by SYNDYMA 100MG/4ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

<strong>How is SYNDYMA 100MG/4ML INJECTION administered?</strong>Arrow

SYNDYMA 100MG/4ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

<strong>Can I take SYNDYMA 100MG/4ML INJECTION if I am pregnant?</strong>Arrow

Inform your physician before starting your treatment with SYNDYMA 100MG/4ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

NULL interaction of SYNDYMA 100MG/4ML INJECTION with other drungsArrow

NULL interaction of SYNDYMA 100MG/4ML INJECTION with other drungs

What conditions should I inform my doctor about before taking SYNDYMA 100MG/4ML INJECTION?Arrow

It is vital to inform your physician before taking SYNDYMA 100MG/4ML INJECTION if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to SYNDYMA 100MG/4ML INJECTION or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

What is Bevacizumab and why is it used in SYNDYMA 100MG/4ML INJECTION?Arrow

BEVACIZUMAB is molecule/combination used for making SYNDYMA 100MG/4ML INJECTION.

For what type of oncology (cancer) treatment is SYNDYMA 100MG/4ML INJECTION prescribed?Arrow

SYNDYMA 100MG/4ML INJECTION is prescribed for {Oncology} ailments/disease/conditions.

References

Book Icon

Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

CIPLA PHARMACEUTICAL COMPANY LIMITED

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