BEVAZZA 100MG/4ML INJECTION
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BEVAZZA 100MG/4ML INJECTION
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BEVAZZA 100MG/4ML INJECTION

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BEVAZZA 100MG/4ML INJECTION

By LUPIN LIMITED

MRP

₹

20062.6

₹9660

51.85 % OFF

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Product DetailsArrow

About BEVAZZA 100MG/4ML INJECTION

  • BEVAZZA 100MG/4ML INJECTION contains Bevacizumab, an anticancer medicine designed to inhibit tumor growth. It is used alongside other chemotherapy drugs to treat several cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It's also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer. Women of childbearing potential should use effective birth control during treatment and for at least six months after the last dose to prevent harm to a potential fetus. This medication is not recommended for children and adolescents under 18 years of age.
  • If you are planning to have children in the future, discuss options for preserving your ovaries with your doctor before starting BEVAZZA 100MG/4ML INJECTION, as it may impair fertility in women. Breastfeeding is also not advised while taking this medication, as it could negatively affect the baby's development. It is important to openly discuss your medical history and intentions with your healthcare provider to ensure the safest and most effective treatment plan.
  • BEVAZZA 100MG/4ML INJECTION is typically administered in combination with other chemotherapy agents. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. Inform your doctor if you have pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment. This medicine should be avoided for 28 days before and after any surgery due to the risk of poor wound healing and increased bleeding complications. Report any dental issues requiring surgery to your doctor before treatment. Seek immediate medical attention if you experience visual changes or confusion to prevent potential complications.

Uses of BEVAZZA 100MG/4ML INJECTION

  • BEVAZZA 100MG/4ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This medication targets and disrupts the growth of cancerous cells within the brain, specifically addressing the aggressive nature of glioblastoma multiforme.
  • Persistent, recurrent, or metastatic breast cancer. BEVAZZA 100MG/4ML INJECTION helps manage breast cancer that has either returned after treatment, spread to other parts of the body, or continues to persist despite prior therapies, providing a targeted approach to reduce cancer progression.
  • Metastatic cervical cancer. This injection is utilized in cases where cervical cancer has spread to distant sites in the body. BEVAZZA 100MG/4ML INJECTION works to inhibit the growth and spread of these cancerous cells, aiming to improve outcomes and manage the disease effectively.
  • Advanced kidney cancer. BEVAZZA 100MG/4ML INJECTION is employed to treat advanced stages of kidney cancer, offering a therapeutic option to slow the progression of the disease and extend survival rates in patients with this challenging condition.
  • Metastatic colorectal cancer. This medication targets colorectal cancer that has spread to other organs. BEVAZZA 100MG/4ML INJECTION helps to control the growth and spread of the cancer, improving the quality of life for patients with metastatic disease.
  • Advanced non-small-cell lung cancer. BEVAZZA 100MG/4ML INJECTION is used in the treatment of advanced non-small-cell lung cancer to inhibit the growth of cancerous cells and extend survival rates, providing patients with a chance for improved outcomes.
  • Liver Cancer- Hepatocellular carcinoma. This injection is indicated for the treatment of hepatocellular carcinoma, the most common type of liver cancer. BEVAZZA 100MG/4ML INJECTION aims to reduce tumor size and slow the progression of the disease, improving overall prognosis.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. BEVAZZA 100MG/4ML INJECTION provides a therapeutic option for managing cancers affecting the female reproductive system and the lining of the abdomen, aiming to improve patient outcomes and overall survival.

Side Effects of BEVAZZA 100MG/4ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for BEVAZZA 100MG/4ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with BEVAZZA 100MG/4ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of BEVAZZA 100MG/4ML INJECTIONArrow

  • Your physician or nurse will administer BEVAZZA 100MG/4ML INJECTION as an intravenous infusion. This means the medication is delivered directly into your vein through a small tube. The infusion process allows for controlled and gradual administration of the drug, ensuring it is properly absorbed into your bloodstream.
  • Prior to administration, the BEVAZZA 100MG/4ML INJECTION will be diluted by a healthcare professional. This dilution process is crucial to ensure the medication is at the appropriate concentration for safe and effective delivery. The specific diluent and volume used will be determined by your doctor or nurse based on your individual needs and the prescribed treatment protocol.
  • It is important to note that the diluted BEVAZZA 100MG/4ML INJECTION should be administered immediately after dilution. This is because the stability of the diluted solution may decrease over time, potentially affecting its efficacy and safety. Your healthcare provider will ensure that the infusion is started promptly after the dilution process.

How to store BEVAZZA 100MG/4ML INJECTION?Arrow

  • Keep BEVAZZA 100MG INJ away from the reach of children and pets.
  • Store BEVAZZA 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of BEVAZZA 100MG/4ML INJECTIONArrow

  • BEVAZZA 100MG/4ML INJECTION is a targeted therapy utilized in the treatment of several advanced cancers. As a recombinant humanized monoclonal antibody, it operates by precisely targeting and binding to vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein found in the lining of blood and lymph vessels. By binding to VEGF-A, the medication disrupts its interaction with its receptors.
  • This disruption inhibits the formation of new blood vessels, a process known as angiogenesis. Tumors require a constant supply of oxygen and nutrients to grow and spread. These are supplied by the newly formed blood vessels. By inhibiting angiogenesis, BEVAZZA 100MG/4ML INJECTION deprives the tumor of these essential resources.
  • Consequently, the growth and spread of the cancer are slowed down. BEVAZZA 100MG/4ML INJECTION helps to control the disease's progression and potentially extend the patient's life. This targeted approach minimizes damage to healthy cells, reducing some of the side effects associated with traditional chemotherapy.

How to use BEVAZZA 100MG/4ML INJECTIONArrow

  • BEVAZZA 100MG/4ML INJECTION will be administered to you by your doctor or nurse through an intravenous (IV) infusion. This means the medication is delivered directly into your vein over a specific period. The healthcare professional will carefully dilute BEVAZZA 100MG/4ML INJECTION with a suitable solution before administration to ensure it is given safely and effectively.
  • The prepared infusion solution should be used immediately after dilution. This is because the stability of the diluted medication might decrease over time, potentially affecting its potency. Your doctor or nurse will follow strict guidelines to prepare and administer the infusion promptly.
  • The duration of the infusion can vary depending on several factors, including the specific dosage prescribed by your doctor and your individual response to the medication. Your healthcare provider will closely monitor you during the infusion for any signs of adverse reactions or complications.
  • It is crucial to inform your doctor or nurse if you experience any discomfort, pain, or unusual symptoms during the infusion. They can then take appropriate measures to manage these symptoms and ensure your comfort throughout the procedure. Regular blood pressure monitoring is essential during and after BEVAZZA 100MG/4ML INJECTION infusion to detect any fluctuations and respond accordingly.

FAQs

Is BEVAZZA 100MG/4ML INJECTION used as standalone treatment in cancers?Arrow

BEVAZZA 100MG/4ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use BEVAZZA 100MG/4ML INJECTION?Arrow

While for women with reproductive potential subjected to BEVAZZA 100MG/4ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with BEVAZZA 100MG/4ML INJECTION?Arrow

BEVAZZA 100MG/4ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of BEVAZZA 100MG/4ML INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by BEVAZZA 100MG/4ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is BEVAZZA 100MG/4ML INJECTION administered?Arrow

BEVAZZA 100MG/4ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take BEVAZZA 100MG/4ML INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with BEVAZZA 100MG/4ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Is there any interaction of BEVAZZA 100MG/4ML INJECTION with other drugs?Arrow

There is no known interaction of BEVAZZA 100MG/4ML INJECTION with other drugs.

What conditions should I inform my doctor about before taking BEVAZZA 100MG/4ML INJECTION?Arrow

It is vital to inform your physician before taking BEVAZZA 100MG/4ML INJECTION if you have the following conditions: *Have conditions involving inflammation in the stomach (ulcer, colitis). *Experience allergic reactions to BEVAZZA 100MG/4ML INJECTION or its ingredients. *Have recently undergone surgery as it is associated with the risk of bleeding. *Have diabetes, hypertension, or heart problems.

What is Bevacizumab and why is it used for making BEVAZZA 100MG/4ML INJECTION?Arrow

Bevacizumab is a molecule used for making BEVAZZA 100MG/4ML INJECTION. It acts as the active ingredient of the medicine.

For what ailments is BEVAZZA 100MG/4ML INJECTION mainly used to treat?Arrow

BEVAZZA 100MG/4ML INJECTION is mainly prescribed for treating ailments related to Oncology (cancers).

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

LUPIN LIMITED

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