AVANGIO 400MG/16ML INJECTION
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AVANGIO 400MG/16ML INJECTION
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AVANGIO 400MG/16ML INJECTION

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AVANGIO 400MG/16ML INJECTION

By PLASMAGEN BIOSCIENCES PVT LTD

MRP

₹

25982

₹25982

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Product DetailsArrow

About AVANGIO 400MG/16ML INJECTION

  • AVANGIO 400MG/16ML INJECTION is an anticancer medication containing Bevacizumab as its active ingredient. It works by preventing tumor growth and is used alongside other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It's also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer. If you are a woman, it's crucial to use effective birth control during treatment and for at least six months after the final dose. This medication is not suitable for adolescents and children under 18 years of age. If you are planning for a future pregnancy, discuss options for preserving your ovaries with your doctor, as this medicine can potentially cause fertility problems in women. It is also advised to avoid breastfeeding during treatment, as the medicine could interfere with the baby's growth and development.
  • AVANGIO 400MG/16ML INJECTION is frequently given in conjunction with other chemotherapy medications. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. It's important to inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment with this medicine. Avoid taking this medicine for 28 days before and after any surgical procedures due to the risk of poor wound healing and increased bleeding complications. It is advised to inform your doctor about any planned dental procedures or existing dental issues before starting AVANGIO 400MG/16ML INJECTION treatment. If you experience any visual changes or confusion while taking this medicine, notify your doctor immediately to prevent potential complications. This ensures timely management and reduces the risk of severe adverse effects, contributing to better overall health outcomes during your cancer treatment.

Uses of AVANGIO 400MG/16ML INJECTION

  • AVANGIO 400MG/16ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This is a type of aggressive brain tumor that originates from glial cells.
  • Persistent, recurrent, or metastatic breast cancer. This refers to breast cancer that has either returned after treatment, or has spread to other parts of the body.
  • Metastatic cervical cancer. This indicates cervical cancer that has spread from the cervix to distant organs or tissues.
  • Advanced kidney cancer. This signifies kidney cancer that has spread beyond the kidney to other parts of the body.
  • Metastatic colorectal cancer. This involves cancer that began in the colon or rectum and has spread to other areas of the body.
  • Advanced non-small-cell lung cancer. This refers to a type of lung cancer that is not small cell lung cancer and has spread significantly.
  • Liver Cancer- Hepatocellular carcinoma. This is a type of cancer that originates in the liver cells.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. This includes cancers that originate in the female reproductive organs and peritoneum.

Side Effects of AVANGIO 400MG/16ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. AVANGIO 400MG/16ML INJECTION may cause serious and common side effects.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for AVANGIO 400MG/16ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with AVANGIO 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of AVANGIO 400MG/16ML INJECTIONArrow

  • AVANGIO 400MG/16ML INJECTION will be administered to you by your doctor or nurse through an intravenous (IV) infusion. This means the medication will be delivered directly into your vein over a specific period.
  • It is crucial that the infusion begins immediately after the solution is prepared and diluted to maintain its stability and effectiveness. The healthcare professional preparing the infusion will follow strict guidelines to ensure the correct concentration and prevent any contamination.
  • The duration of the infusion and the frequency of treatments will be determined by your doctor based on your individual needs, the condition being treated, and your response to the medication. It is important to adhere to the prescribed schedule for optimal results.
  • If you have any questions or concerns about the administration of AVANGIO 400MG/16ML INJECTION, please do not hesitate to ask your doctor or nurse. They are there to provide you with the information and support you need throughout your treatment.

How to store AVANGIO 400MG/16ML INJECTION?Arrow

  • Keep AVANGIO 400MG INJ 16ML away from the reach of children and pets.
  • Store AVANGIO 400MG INJ 16ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of AVANGIO 400MG/16ML INJECTIONArrow

  • AVANGIO 400MG/16ML INJECTION is a targeted therapy employing a recombinant humanized monoclonal antibody to combat various advanced cancers. This medication operates by selectively attaching to vascular endothelial growth factor A (VEGF-A), a protein found in the inner lining of blood and lymph vessels.
  • By binding to VEGF-A, AVANGIO 400MG/16ML INJECTION disrupts the interaction between VEGF-A and its corresponding receptors. This interruption is crucial because VEGF-A plays a vital role in angiogenesis, the formation of new blood vessels.
  • Tumors require a constant supply of oxygen and nutrients to grow and spread. These substances are delivered via blood vessels. AVANGIO 400MG/16ML INJECTION inhibits the formation of new blood vessels that feed the tumor, effectively starving it and hindering its growth.
  • The inhibition of angiogenesis caused by AVANGIO 400MG/16ML INJECTION effectively slows down the progression of cancer by limiting the tumor's ability to expand and metastasize. This targeted approach minimizes damage to healthy cells, potentially leading to improved outcomes and quality of life for patients.
  • AVANGIO 400MG/16ML INJECTION represents a significant advancement in cancer treatment, offering a precise and effective way to target the mechanisms that fuel tumor growth. Consult with your doctor to determine if this medication is appropriate for your specific condition.

How to use AVANGIO 400MG/16ML INJECTIONArrow

  • AVANGIO 400MG/16ML INJECTION will be administered to you by your doctor or nurse through an intravenous (IV) infusion. This means the medication is delivered directly into your vein over a specific period. The healthcare professional will carefully prepare the solution by diluting AVANGIO 400MG/16ML INJECTION with a compatible intravenous fluid to ensure it's safe and effective for infusion.
  • The infusion should commence immediately after the dilution process. This is crucial to maintain the stability and integrity of the drug. The healthcare provider will monitor you closely during the infusion for any signs of adverse reactions or complications. The duration of the infusion will be determined by your doctor based on your individual needs and medical condition. It's important to inform your doctor or nurse immediately if you experience any discomfort, pain, swelling, or irritation at the injection site during the infusion.
  • Do not attempt to self-administer AVANGIO 400MG/16ML INJECTION. It must be given by a qualified healthcare professional. If you have any questions or concerns about the administration process, don't hesitate to ask your doctor or nurse.

FAQs

Is AVANGIO 400MG/16ML INJECTION used as standalone treatment in cancers?Arrow

AVANGIO 400MG/16ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use AVANGIO 400MG/16ML INJECTION?Arrow

While for women with reproductive potential subjected to AVANGIO 400MG/16ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with AVANGIO 400MG/16ML INJECTION?Arrow

AVANGIO 400MG/16ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of AVANGIO 400MG/16ML INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by AVANGIO 400MG/16ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is AVANGIO 400MG/16ML INJECTION administered?Arrow

AVANGIO 400MG/16ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take AVANGIO 400MG/16ML INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with AVANGIO 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

NULL interaction of AVANGIO 400MG/16ML INJECTION with other drungsArrow

Currently, there are no known negative interactions of AVANGIO 400MG/16ML INJECTION with other medications. It is always best to inform your doctor if you are taking any medications.

What should I tell my doctor before taking AVANGIO 400MG/16ML INJECTION?Arrow

It is vital to inform your physician before taking AVANGIO 400MG/16ML INJECTION if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to AVANGIO 400MG/16ML INJECTION or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

What is AVANGIO 400MG/16ML INJECTION made of?Arrow

BEVACIZUMAB is molecule/combination used for making AVANGIO 400MG/16ML INJECTION.

For what conditions is AVANGIO 400MG/16ML INJECTION prescribed?Arrow

AVANGIO 400MG/16ML INJECTION is prescribed for ailments/diseases/conditions related to {Oncology}.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC).

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Roche Group, U.S FDA.

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Roche Group,Bevacizumab Injection, Indication.

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Ratings & Review

Awesome experience every time i get medicine on time and they have delivery on time also staff are very cooperative and knowledgeable

Tarun Ezava

•

Reviewed on 22-06-2023

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(5/5)

Good series, satisfied customer

Sameer Jadhav

•

Reviewed on 06-01-2024

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(5/5)

Very good and quik responce for all medicines

Binal Doshi

•

Reviewed on 03-01-2023

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(5/5)

Good discount available on Generic medicines and supportive staff. Thank you.

ujjawal bhatt

•

Reviewed on 08-01-2024

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(5/5)

Good. Provides medicines at reasonable rates.

Jiji Varughese

•

Reviewed on 08-02-2024

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(4/5)

Marketer / Manufacturer Details

PLASMAGEN BIOSCIENCES PVT LTD

Country of Origin -

India

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