KRABEVA 400MG/16ML INJECTION
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KRABEVA 400MG/16ML INJECTION
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KRABEVA 400MG/16ML INJECTION

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KRABEVA 400MG/16ML INJECTION

By BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

MRP

43212

₹17170

60.27 % OFF

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Product DetailsArrow

About KRABEVA 400MG/16ML INJECTION

  • KRABEVA 400MG/16ML INJECTION is an anticancer medication containing Bevacizumab, designed to inhibit tumor growth. It's used alongside chemotherapy to treat metastatic breast, brain, cervical, kidney, lung, and colorectal cancers. It also treats cancers of the ovary, fallopian tube, or primary peritoneum. Effective birth control is crucial during and for six months post-treatment.
  • This injection is not recommended for those under 18. If future pregnancy is desired, discuss ovary preservation with your doctor, as it can impair female fertility. Breastfeeding should be avoided due to potential interference with infant growth and development.
  • KRABEVA 400MG/16ML INJECTION is often administered with other chemotherapy drugs. Common side effects include constipation, appetite loss, runny nose, fever, skin issues, and weight loss. Inform your doctor about any history of high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment.
  • Avoid taking KRABEVA 400MG/16ML INJECTION for 28 days before and after surgery due to risks of poor wound healing and bleeding complications. Report any dental issues requiring surgery. Seek immediate medical attention for visual changes or confusion to prevent complications. This medication targets and blocks a protein called vascular endothelial growth factor (VEGF). By blocking VEGF, KRABEVA 400MG/16ML INJECTION helps to prevent the formation of new blood vessels that tumors need to grow. This can slow the growth and spread of cancer cells.
  • Regular monitoring by your healthcare provider is essential to assess the effectiveness of the treatment and manage any potential side effects. It’s important to maintain open communication with your doctor throughout your treatment with KRABEVA 400MG/16ML INJECTION to ensure the best possible outcome. Remember that this drug is a part of cancer treatment, so it can only help you to get well in coordination with other drugs and therapies, so it is important to continue the other treatments as advised.

Uses of KRABEVA 400MG/16ML INJECTION

  • KRABEVA 400MG/16ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This is an aggressive type of cancer that begins within the brain.
  • Persistent, recurrent, or metastatic breast cancer: This means the cancer has come back or has spread to other parts of the body.
  • Metastatic cervical cancer: Cervical cancer that has spread to distant parts of the body.
  • Advanced kidney cancer: Kidney cancer that has spread or cannot be treated with surgery.
  • Metastatic colorectal cancer: Colorectal cancer that has spread to distant parts of the body.
  • Advanced non-small-cell lung cancer: Lung cancer that has spread or cannot be treated with surgery.
  • Liver Cancer- Hepatocellular carcinoma: This is the most common type of liver cancer.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer: These cancers begin in the female reproductive organs.

Side Effects of KRABEVA 400MG/16ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects may include headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores and dryness, and shortness of breath. Common side effects can include numbness in hands or feet, weakness and lack of energy, diarrhea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, and back pain.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for KRABEVA 400MG/16ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with KRABEVA 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of KRABEVA 400MG/16ML INJECTIONArrow

  • KRABEVA 400MG/16ML INJECTION is administered by a healthcare professional, such as a physician or nurse, through intravenous infusion. This means the medication is delivered directly into your vein over a specific period. The infusion process requires careful monitoring to ensure patient safety and efficacy of the drug.
  • It is crucial that the infusion begins immediately after the KRABEVA 400MG/16ML INJECTION is properly diluted. This immediate administration is essential to maintain the stability and effectiveness of the medication. Delaying the infusion after dilution may compromise the drug's properties and potentially reduce its therapeutic benefits.
  • The healthcare provider will determine the appropriate dosage and infusion rate based on individual patient factors, such as body weight, medical condition, and other medications being taken. Close adherence to the prescribed dosage and infusion schedule is vital for achieving the desired clinical outcome and minimizing potential side effects. Patients should report any discomfort or adverse reactions experienced during the infusion to their healthcare provider immediately.

How to store KRABEVA 400MG/16ML INJECTION?Arrow

  • Keep KRABEVA 400MG INJ away from the reach of children and pets.
  • Store KRABEVA 400MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of KRABEVA 400MG/16ML INJECTIONArrow

  • KRABEVA 400MG/16ML INJECTION is a targeted therapy utilizing a recombinant humanized monoclonal antibody, designed to combat various advanced cancers by disrupting the growth and spread of cancerous cells.
  • This medication works by specifically targeting and binding to vascular endothelial growth factor A (VEGF-A), a protein crucial for the formation of new blood vessels. VEGF-A is found in the lining of blood and lymph vessels.
  • By blocking the interaction between VEGF-A and its receptors, KRABEVA 400MG/16ML INJECTION effectively inhibits angiogenesis, the process by which tumors develop their own blood supply.
  • This interference with blood vessel formation deprives the tumor of essential oxygen and nutrients, slowing down its growth and hindering its ability to metastasize (spread to other parts of the body).
  • Ultimately, KRABEVA 400MG/16ML INJECTION helps to control the progression of cancer by targeting a key mechanism that fuels tumor growth and dissemination.
  • This targeted approach aims to minimize damage to healthy cells, potentially reducing the severity of side effects compared to traditional chemotherapy.

How to use KRABEVA 400MG/16ML INJECTIONArrow

  • KRABEVA 400MG/16ML INJECTION will be administered to you by your doctor or nurse through an intravenous infusion. This means the medication will be delivered directly into your vein over a specific period.
  • The healthcare professional will carefully dilute KRABEVA 400MG/16ML INJECTION before administering it to you. This dilution process is crucial to ensure the medication is delivered safely and effectively.
  • It's important to note that the infusion should commence immediately after the dilution process is complete. This is to maintain the stability and efficacy of the medication.
  • The duration of the infusion and the dosage you receive will be determined by your doctor based on your specific medical condition and response to treatment. Please follow your doctor's instructions carefully.
  • If you have any questions or concerns about the administration of KRABEVA 400MG/16ML INJECTION, don't hesitate to ask your doctor or nurse. They are there to provide you with the information and support you need throughout your treatment.

FAQs

<p><strong>Is KRABEVA 400MG/16ML INJECTION used as standalone treatment in cancers?</strong></p>Arrow

KRABEVA 400MG/16ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

<p><strong>Is it safe for women to use KRABEVA 400MG/16ML INJECTION?</strong></p>Arrow

While for women with reproductive potential subjected to KRABEVA 400MG/16ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility. 

<p><strong>Is it safe to undergo a surgery during the treatment with KRABEVA 400MG/16ML INJECTION?</strong></p>Arrow

KRABEVA 400MG/16ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

<p><strong>Do the side effects of KRABEVA 400MG/16ML INJECTION last for a chronic period?</strong></p>Arrow

All the side effects that are relatively caused by KRABEVA 400MG/16ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

<p><strong>How is KRABEVA 400MG/16ML INJECTION administered?</strong></p>Arrow

KRABEVA 400MG/16ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age.  The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

<p><strong>Can I take KRABEVA 400MG/16ML INJECTION if I am pregnant?&nbsp;</strong></p>Arrow

Inform your physician before starting your treatment with KRABEVA 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

NULL interaction of KRABEVA 400MG/16ML INJECTION with other drungsArrow

It is always best to consult with your doctor or pharmacist before using other medications with KRABEVA 400MG/16ML INJECTION.

<p style="text-align:justify;">It is vital to inform your physician before taking KRABEVA 400MG/16ML INJECTION if you have the following conditions:</p><ul><li>Have conditions involving inflammation in the stomach (ulcer, colitis).</li><li>Experience allergic reactions to KRABEVA 400MG/16ML INJECTION or its ingredients.</li><li>Have recently undergone surgery as it is associated with the risk of bleeding.</li><li>Have diabetes, hypertension, or heart problems.</li></ul>Arrow

It is important to inform your doctor about conditions such as inflammation in the stomach (ulcer, colitis), allergies to KRABEVA 400MG/16ML INJECTION or its ingredients, recent surgery, diabetes, hypertension, or heart problems.

BEVACIZUMAB is molecule/combination used for making KRABEVA 400MG/16ML INJECTION.Arrow

BEVACIZUMAB molecule/combination is used for making KRABEVA 400MG/16ML INJECTION.

For what ailments/diseases/conditions is KRABEVA 400MG/16ML INJECTION prescribed?Arrow

KRABEVA 400MG/16ML INJECTION is used in Oncology, meaning it is prescribed for conditions like cancer.

Does KRABEVA 400MG/16ML INJECTION help in cancer treatment?Arrow

Yes, KRABEVA 400MG/16ML INJECTION, which contains bevacizumab, helps in treating some types of cancer. It works by blocking the growth of blood vessels that tumors need to grow and spread.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC).

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Roche Group, U.S FDA

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Roche Group, Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

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India

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KRABEVA 400MG/16ML INJECTION

MRP

43212

₹17170

60.27 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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