IVZUMAB 400 INJECTION
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IVZUMAB 400 INJECTION
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IVZUMAB 400 INJECTION

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IVZUMAB 400 INJECTION

By RPG LIFE SCIENCES LIMITED

MRP

52500

₹16335

68.89 % OFF

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Product DetailsArrow

About IVZUMAB 400 INJECTION

  • IVZUMAB 400 INJECTION is an anticancer medication containing Bevacizumab as its active ingredient. This medication is designed to inhibit tumor growth and is used in conjunction with other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It is also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer.
  • During treatment with IVZUMAB 400 INJECTION and for at least six months after the final dose, it is crucial to use effective birth control methods. This medication is not recommended for adolescents and children under 18 years of age. If you are a woman planning for pregnancy in the future, discuss options for ovary preservation with your doctor, as IVZUMAB 400 INJECTION may lead to fertility problems. Breastfeeding should be avoided while taking this medication, as it may interfere with the baby's growth and development.
  • IVZUMAB 400 INJECTION is often administered alongside other chemotherapy agents. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. It's important to inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment with this medication. Avoid taking IVZUMAB 400 INJECTION for 28 days before and after surgery due to the risk of poor wound healing and increased bleeding complications.
  • Report any dental issues requiring surgery to your doctor before initiating treatment. Seek immediate medical attention if you experience any visual changes or confusion. This medicine can sometimes cause serious side effects, and prompt reporting helps prevent complications. Regular monitoring and open communication with your healthcare team are essential for safe and effective treatment with IVZUMAB 400 INJECTION.

Uses of IVZUMAB 400 INJECTION

  • IVZUMAB 400 INJECTION is indicated to treat the following conditions:
  • Glioblastoma multiforme (brain cancer)
  • Persistent, recurrent, or metastatic breast cancer
  • Metastatic cervical cancer
  • Advanced kidney cancer
  • Metastatic colorectal cancer
  • Advanced non-small-cell lung cancer
  • Liver Cancer- Hepatocellular carcinoma
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

Side Effects of IVZUMAB 400 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for IVZUMAB 400 INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with IVZUMAB 400 INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of IVZUMAB 400 INJECTIONArrow

  • Your physician or nurse will administer IVZUMAB 400 INJECTION as an intravenous infusion. This ensures the medication is delivered directly into your bloodstream for optimal absorption and effectiveness. The infusion process typically involves a slow and controlled administration of the diluted medication over a specific period, allowing your body to gradually adjust to the treatment. The healthcare professional administering the IVZUMAB 400 INJECTION will closely monitor you throughout the infusion for any signs of adverse reactions or discomfort. It is crucial to inform them immediately if you experience any unusual symptoms during the procedure. The infusion should be given immediately after the dilution to maintain the stability and efficacy of the drug. This practice minimizes the risk of degradation or contamination, ensuring you receive the full therapeutic benefit of IVZUMAB 400 INJECTION.
  • The exact duration of the infusion will depend on factors such as your individual response to the medication and the specific protocol followed by your healthcare provider. You will typically be seated or lying comfortably during the infusion process. Feel free to ask any questions you have regarding the procedure or the medication itself. Your healthcare team is there to provide you with comprehensive information and support throughout your treatment journey.

How to store IVZUMAB 400 INJECTION?Arrow

  • Keep IVZUMAB 400MG INJ 16ML away from the reach of children and pets.
  • Store IVZUMAB 400MG INJ 16ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of IVZUMAB 400 INJECTIONArrow

  • IVZUMAB 400 INJECTION is a targeted therapy designed to combat various advanced cancers. It contains a recombinant humanized monoclonal antibody that selectively binds to vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein found in the lining of blood and lymph vessels, and it plays a crucial role in angiogenesis, the formation of new blood vessels.
  • By binding to VEGF-A, IVZUMAB 400 INJECTION disrupts the interaction between VEGF-A and its receptors. This interruption is significant because it inhibits the signaling pathways that promote the growth of new blood vessels. Tumors require a constant supply of oxygen and nutrients to grow and spread. These resources are delivered through the newly formed blood vessels.
  • Therefore, by preventing angiogenesis, IVZUMAB 400 INJECTION effectively cuts off the tumor's lifeline. This deprives the cancer cells of the essential resources they need to proliferate, leading to a slowdown in the rate of cancer progression. This targeted approach helps to control the growth and spread of the cancer cells.

How to use IVZUMAB 400 INJECTIONArrow

  • IVZUMAB 400 INJECTION will be administered to you by a trained healthcare professional, such as your physician or nurse, through an intravenous (IV) infusion. This method ensures the medication is delivered directly into your bloodstream for optimal absorption and effectiveness. The IV infusion process involves carefully inserting a small needle into a vein in your arm and connecting it to a bag containing the diluted IVZUMAB 400 INJECTION solution.
  • It's crucial that the infusion begins immediately after the IVZUMAB 400 INJECTION has been properly diluted according to the prescribing instructions. This is to maintain the stability and integrity of the medication. The healthcare provider will closely monitor you throughout the infusion process for any signs of adverse reactions or complications. The duration of the infusion can vary, so it's important to follow your healthcare provider's instructions carefully and ask any questions you may have about the process.
  • The dosage and frequency of IVZUMAB 400 INJECTION administrations will be determined by your doctor based on your specific medical condition and individual needs. It's important to attend all scheduled appointments and follow your doctor's recommendations to ensure the best possible outcome from your treatment. Do not self-administer this medication.

FAQs

<strong>Is IVZUMAB 400 INJECTION used as standalone treatment in cancers?</strong>Arrow

IVZUMAB 400 INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

<strong>Is it safe for women to use IVZUMAB 400 INJECTION?</strong>Arrow

While for women with reproductive potential subjected to IVZUMAB 400 INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility. 

<strong>Is it safe to undergo a surgery during the treatment with IVZUMAB 400 INJECTION?</strong>Arrow

IVZUMAB 400 INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

<strong>Do the side effects of IVZUMAB 400 INJECTION last for a chronic period?</strong>Arrow

All the side effects that are relatively caused by IVZUMAB 400 INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

<strong>How is IVZUMAB 400 INJECTION administered?</strong>Arrow

IVZUMAB 400 INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

<strong>Can I take IVZUMAB 400 INJECTION if I am pregnant?</strong>Arrow

Inform your physician before starting your treatment with IVZUMAB 400 INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Does IVZUMAB 400 INJECTION interact with other drugs?Arrow

There is no known interaction of IVZUMAB 400 INJECTION with other drugs.

What conditions should I inform my doctor about before taking IVZUMAB 400 INJECTION?Arrow

It is vital to inform your physician before taking IVZUMAB 400 INJECTION if you have the following conditions: * Have conditions involving inflammation in the stomach (ulcer, colitis). * Experience allergic reactions to IVZUMAB 400 INJECTION or its ingredients. * Have recently undergone surgery as it is associated with the risk of bleeding. * Have diabetes, hypertension, or heart problems.

What molecule/combination is used for making IVZUMAB 400 INJECTION?Arrow

BEVACIZUMAB is molecule/combination used for making IVZUMAB 400 INJECTION.

For what ailments/diseases/conditions is IVZUMAB 400 INJECTION prescribed?Arrow

IVZUMAB 400 INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

RPG LIFE SCIENCES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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