BEVAZZA 400MG/16ML INJECTION
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BEVAZZA 400MG/16ML INJECTION
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BEVAZZA 400MG/16ML INJECTION

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BEVAZZA 400MG/16ML INJECTION

By LUPIN LIMITED

MRP

42787

₹16500

61.44 % OFF

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Product DetailsArrow

About BEVAZZA 400MG/16ML INJECTION

  • BEVAZZA 400MG/16ML INJECTION is an anticancer medication containing Bevacizumab as its active ingredient. It is designed to inhibit tumor growth and is often used alongside other chemotherapy drugs in the treatment of various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It also finds application in treating cancers of the ovary, fallopian tube, or primary peritoneal cancer. Due to potential risks to a developing fetus, it is crucial to use effective contraception during treatment and for at least six months following the final dose. This medication is not suitable for children and adolescents under 18 years of age. If you are a woman planning to become pregnant in the future, discuss options for ovarian preservation with your doctor, as BEVAZZA 400MG/16ML INJECTION can impact fertility. Breastfeeding is also discouraged while taking this medication, as it may negatively affect the baby's growth and development.
  • BEVAZZA 400MG/16ML INJECTION is typically administered in conjunction with other chemotherapy agents. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. It's essential to inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before commencing treatment. To minimize the risk of impaired wound healing and bleeding complications, avoid taking this medicine for 28 days before and after any surgical procedures. Report any dental issues requiring surgery to your doctor before starting BEVAZZA 400MG/16ML INJECTION treatment. Promptly inform your doctor if you experience any visual disturbances or confusion to prevent potential complications. This proactive approach ensures the safest and most effective use of the medication throughout your cancer treatment journey.

Uses of BEVAZZA 400MG/16ML INJECTION

  • BEVAZZA 400MG/16ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This is a type of aggressive brain tumor. BEVAZZA 400MG/16ML INJECTION targets the blood vessels that feed the tumor, helping to slow its growth.
  • Persistent, recurrent, or metastatic breast cancer. BEVAZZA 400MG/16ML INJECTION can be used when breast cancer has spread to other parts of the body or keeps returning, to help control the disease.
  • Metastatic cervical cancer. This medication is an option for treating cervical cancer that has spread to distant sites in the body.
  • Advanced kidney cancer. BEVAZZA 400MG/16ML INJECTION can be used in the treatment of advanced renal cell carcinoma, a common type of kidney cancer.
  • Metastatic colorectal cancer. When colorectal cancer spreads, BEVAZZA 400MG/16ML INJECTION can be part of the treatment plan to slow the progression of the disease.
  • Advanced non-small-cell lung cancer. This injection may be used to treat certain types of advanced non-small cell lung cancer.
  • Liver Cancer- Hepatocellular carcinoma. BEVAZZA 400MG/16ML INJECTION is sometimes used in treating hepatocellular carcinoma, which is a type of liver cancer.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. BEVAZZA 400MG/16ML INJECTION can be used in the treatment of these gynecological cancers.

Side Effects of BEVAZZA 400MG/16ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for BEVAZZA 400MG/16ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with BEVAZZA 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of BEVAZZA 400MG/16ML INJECTIONArrow

  • Your physician or nurse will administer BEVAZZA 400MG/16ML INJECTION as an intravenous infusion. This means the medication will be delivered directly into your vein through a small tube. The infusion should be given immediately after dilution to ensure the stability and efficacy of the drug. The healthcare professional will carefully monitor you during the infusion for any signs of adverse reactions or complications. The rate of infusion will be controlled to minimize the risk of side effects. It is important to inform your doctor or nurse if you experience any discomfort, such as pain, swelling, or redness at the injection site, during the infusion. Proper administration and monitoring are crucial for the safe and effective use of BEVAZZA 400MG/16ML INJECTION.
  • The dosage and frequency of BEVAZZA 400MG/16ML INJECTION will be determined by your doctor based on your individual needs and the specific condition being treated. It's vital to adhere to the prescribed schedule and complete the entire course of treatment, even if you start to feel better, unless your doctor advises otherwise. Do not attempt to self-administer this medication. It is intended for use under the direct supervision of a qualified healthcare professional.

How to store BEVAZZA 400MG/16ML INJECTION?Arrow

  • Keep BEVAZZA 400MG INJ away from the reach of children and pets.
  • Store BEVAZZA 400MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of BEVAZZA 400MG/16ML INJECTIONArrow

  • BEVAZZA 400MG/16ML INJECTION is a targeted therapy designed to combat various advanced cancers. It functions as a recombinant humanized monoclonal antibody, meticulously engineered to disrupt the mechanisms that fuel tumor growth and spread.
  • This medication targets a specific protein known as vascular endothelial growth factor A (VEGF-A), which is found in the lining of blood and lymph vessels. VEGF-A plays a crucial role in angiogenesis, the formation of new blood vessels.
  • By selectively binding to VEGF-A, BEVAZZA 400MG/16ML INJECTION prevents it from interacting with its receptors. This crucial interaction is what normally triggers the development of new blood vessels that nourish the tumor.
  • The inhibition of VEGF-A ultimately hinders the formation of these new blood vessels, effectively cutting off the tumor's supply of oxygen and essential nutrients. As a result, the growth and spread of the cancer are significantly slowed down, offering a valuable therapeutic benefit.
  • In simpler terms, BEVAZZA 400MG/16ML INJECTION starves the tumor by preventing it from creating the blood vessels it needs to thrive. This targeted approach helps to control cancer progression and improve patient outcomes.

How to use BEVAZZA 400MG/16ML INJECTIONArrow

  • BEVAZZA 400MG/16ML INJECTION will be administered to you by a doctor or nurse through intravenous infusion. This ensures the medication is delivered directly into your bloodstream, allowing for optimal absorption and effectiveness. The process involves a slow and controlled administration of the diluted medication over a specific period.
  • It is crucial that the infusion begins immediately after the drug has been properly diluted. This minimizes the risk of instability or degradation of the medication, guaranteeing that you receive the full intended dose and benefit. Your healthcare provider will carefully monitor you throughout the infusion process for any signs of adverse reactions or complications.
  • The duration of the infusion and the frequency of treatments will be determined by your doctor based on your individual medical condition, response to treatment, and any other medications you may be taking. It is important to follow your doctor's instructions precisely and to attend all scheduled appointments. Do not hesitate to ask your healthcare provider any questions you may have about the medication or the infusion process.

FAQs

Is BEVAZZA 400MG/16ML INJECTION used as standalone treatment in cancers?Arrow

Bevarest 100mg Injection is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use BEVAZZA 400MG/16ML INJECTION?Arrow

While for women with reproductive potential subjected to BEVAZZA 400MG/16ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with BEVAZZA 400MG/16ML INJECTION?Arrow

BEVAZZA 400MG/16ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of BEVAZZA 400MG/16ML INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by BEVAZZA 400MG/16ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is BEVAZZA 400MG/16ML INJECTION administered?Arrow

BEVAZZA 400MG/16ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take BEVAZZA 400MG/16ML INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with BEVAZZA 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Is there any known interaction of BEVAZZA 400MG/16ML INJECTION with other drugs?Arrow

There is NULL interaction of BEVAZZA 400MG/16ML INJECTION with other drugs

What conditions should I inform my doctor about before taking BEVAZZA 400MG/16ML INJECTION?Arrow

It is vital to inform your physician before taking BEVAZZA 400MG/16ML INJECTION if you have the following conditions: * Have conditions involving inflammation in the stomach (ulcer, colitis). * Experience allergic reactions to BEVAZZA 400MG/16ML INJECTION or its ingredients. * Have recently undergone surgery as it is associated with the risk of bleeding. * Have diabetes, hypertension, or heart problems.

What is Bevacizumab and what is it used for?Arrow

Bevacizumab is a molecule/combination used for making BEVAZZA 400MG/16ML INJECTION. It is a monoclonal antibody that works by targeting and blocking the growth of blood vessels in cancer cells.

What is BEVAZZA 400MG/16ML INJECTION used for in Oncology?Arrow

BEVAZZA 400MG/16ML INJECTION is an anti-angiogenic medicine used in Oncology to treat certain types of cancer. It works by blocking blood vessels from reaching cancer cells, thus preventing tumor growth and spread.

How does BEVAZZA 400MG/16ML INJECTION help in treating cancer in Oncology?Arrow

BEVAZZA 400MG/16ML INJECTION, when used in Oncology, helps in treating cancer by cutting off the blood supply to cancer cells. This medicine inhibits the growth of blood vessels that feed tumors, helping to slow down tumor growth and spread.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC).

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Marketer / Manufacturer Details

LUPIN LIMITED

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BEVAZZA 400MG/16ML INJECTION

BEVAZZA 400MG/16ML INJECTION

MRP

42787

₹16500

61.44 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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