CROGNOC 400MG/16ML INJECTION
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CROGNOC 400MG/16ML INJECTION
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CROGNOC 400MG/16ML INJECTION

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CROGNOC 400MG/16ML INJECTION

By CELON LABORATORIES LTD

MRP

₹

54000

₹16059

70.26 % OFF

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Product DetailsArrow

About CROGNOC 400MG/16ML INJECTION

  • CROGNOC 400MG/16ML INJECTION is an anticancer medicine containing Bevacizumab as its active ingredient. This medication is designed to inhibit tumor growth and is used alongside other chemotherapy drugs to treat various cancers, including metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It is also indicated for cancers of the ovary, fallopian tube, or primary peritoneal cancer. It's crucial to use effective birth control during treatment and for at least six months after the last dose of CROGNOC 400MG/16ML INJECTION.
  • This injection is not recommended for adolescents and children under 18 years of age. If you are a woman planning for pregnancy in the future, discuss with your doctor about the preservation of your ovaries, as this medicine may impair fertility. Breastfeeding is not advised while using this medication, as it could negatively affect the baby's growth and development.
  • CROGNOC 400MG/16ML INJECTION is frequently administered in combination with other chemotherapy drugs. Common side effects include constipation, loss of appetite, runny nose, fever, skin problems, and weight loss. Inform your doctor about any pre-existing conditions such as high blood pressure, high blood sugar, stomach disorders, or heart problems before starting treatment. Avoid taking this medicine for 28 days before and after any surgery, as it can interfere with wound healing and increase the risk of bleeding. It's important to address any dental issues that may require surgery before starting this medication. Report any visual changes or confusion to your doctor immediately to prevent potential complications.
  • Furthermore, patients should be closely monitored for signs of infusion-related reactions, such as allergic reactions, during and after the administration of CROGNOC 400MG/16ML INJECTION. The drug may also increase the risk of thromboembolic events. Regular monitoring of blood pressure is essential throughout the treatment. Patients should maintain adequate hydration and nutrition to manage potential side effects and support overall health. If you experience severe or persistent side effects, consult your healthcare provider for appropriate management strategies.

Uses of CROGNOC 400MG/16ML INJECTION

  • CROGNOC 400MG/16ML INJECTION is indicated to treat the following conditions: Glioblastoma multiforme (brain cancer). This medication targets and helps manage this aggressive form of brain tumor.
  • Persistent, recurrent, or metastatic breast cancer. CROGNOC 400MG/16ML INJECTION is employed to combat breast cancer that has returned, spread, or is resistant to initial treatments.
  • Metastatic cervical cancer. This injection is utilized in the treatment of cervical cancer that has spread to other parts of the body.
  • Advanced kidney cancer. CROGNOC 400MG/16ML INJECTION helps in managing kidney cancer that has progressed to an advanced stage.
  • Metastatic colorectal cancer. This medication is used to treat colorectal cancer that has spread to distant sites in the body.
  • Advanced non-small-cell lung cancer. CROGNOC 400MG/16ML INJECTION plays a role in the therapeutic approach to advanced forms of non-small-cell lung cancer.
  • Liver Cancer - Hepatocellular carcinoma. CROGNOC 400MG/16ML INJECTION is indicated for certain types of liver cancer, specifically hepatocellular carcinoma.
  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer. CROGNOC 400MG/16ML INJECTION is used in the management of cancers originating in these gynecological sites.

Side Effects of CROGNOC 400MG/16ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Blood clots in arteries and blood vessels of lungs
  • Gut perforation
  • Nosebleeds and bleeding risk
  • Heart problems with an increase in heart rate
  • Mouth sores, dryness
  • Shortness of breath
  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhoea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss
  • Changes in taste and speech
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

Safety Advice for CROGNOC 400MG/16ML INJECTIONArrow

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Pregnancy

UNSAFE

Inform your physician before starting your treatment with CROGNOC 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of CROGNOC 400MG/16ML INJECTIONArrow

  • CROGNOC 400MG/16ML INJECTION will be administered to you by a healthcare professional, such as your physician or nurse, through an intravenous infusion. This means the medication will be delivered directly into your vein over a specific period.
  • It's crucial to understand that the intravenous infusion should begin immediately after the CROGNOC 400MG/16ML INJECTION has been properly diluted. This dilution process is essential to ensure the medication is administered safely and effectively. The healthcare provider will follow strict protocols to prepare the solution.
  • The dosage and duration of the infusion will be determined by your doctor based on your individual medical condition, weight, and response to treatment. It is important to adhere to the prescribed dosage schedule and complete the full course of treatment, even if you start feeling better, to ensure the best possible outcome.
  • If you have any questions or concerns about the administration of CROGNOC 400MG/16ML INJECTION, please do not hesitate to ask your doctor or nurse. They are the best resource for information about your specific treatment plan.

How to store CROGNOC 400MG/16ML INJECTION?Arrow

  • Keep CROGNOC 400MG INJ 16ML away from the reach of children and pets.
  • Store CROGNOC 400MG INJ 16ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of CROGNOC 400MG/16ML INJECTIONArrow

  • CROGNOC 400MG/16ML INJECTION is a specialized medication used in the treatment of several advanced cancers. It contains a recombinant humanized monoclonal antibody, which means it's a lab-created protein designed to mimic the body's natural defenses. This antibody is engineered to precisely target a specific protein called vascular endothelial growth factor A (VEGF-A).
  • VEGF-A is crucial for the formation of new blood vessels, a process known as angiogenesis. Tumors rely on angiogenesis to grow and spread because they need a constant supply of oxygen and nutrients. VEGF-A is found in the lining of blood and lymph vessels.
  • CROGNOC 400MG/16ML INJECTION works by selectively binding to VEGF-A, preventing it from interacting with its receptors on the surface of cells. By blocking this interaction, the medication disrupts the signals that promote the growth of new blood vessels. This starves the tumor of the resources it needs to survive and proliferate, effectively slowing down the progression of the cancer. It is important to note that this medication is used as a targeted therapy, aimed at specific molecules involved in cancer growth, potentially leading to fewer side effects compared to traditional chemotherapy.
  • This targeted approach helps to control tumor growth by cutting off its blood supply and inhibiting further spread.

How to use CROGNOC 400MG/16ML INJECTIONArrow

  • CROGNOC 400MG/16ML INJECTION is administered by a healthcare professional, such as a physician or nurse, through intravenous infusion. This means the medication is delivered directly into your vein over a specific period.
  • The preparation process involves diluting the CROGNOC 400MG/16ML INJECTION to achieve the correct concentration for administration. The exact diluent and volume will be determined by your healthcare provider based on your specific needs and the established protocols.
  • It is crucial that the infusion begins immediately after the CROGNOC 400MG/16ML INJECTION is diluted. This is because the stability of the diluted solution can degrade over time, potentially affecting its effectiveness and safety. Your healthcare provider will ensure that the infusion is started promptly to maintain the integrity of the medication.
  • The duration of the infusion can vary depending on the dosage and individual factors. Your healthcare provider will monitor you closely during the infusion for any signs of adverse reactions or complications.
  • If you have any questions or concerns about the administration of CROGNOC 400MG/16ML INJECTION, please do not hesitate to ask your physician or nurse. They can provide you with detailed information and address any anxieties you may have.

FAQs

Is CROGNOC 400MG/16ML INJECTION used as standalone treatment in cancers?Arrow

CROGNOC 400MG/16ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use CROGNOC 400MG/16ML INJECTION?Arrow

While for women with reproductive potential subjected to CROGNOC 400MG/16ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with CROGNOC 400MG/16ML INJECTION?Arrow

CROGNOC 400MG/16ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of CROGNOC 400MG/16ML INJECTION last for a chronic period?Arrow

All the side effects that are relatively caused by CROGNOC 400MG/16ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is CROGNOC 400MG/16ML INJECTION administered?Arrow

CROGNOC 400MG/16ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take CROGNOC 400MG/16ML INJECTION if I am pregnant?Arrow

Inform your physician before starting your treatment with CROGNOC 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

No known interactions of CROGNOC 400MG/16ML INJECTION with other drugs.Arrow

No known interactions of CROGNOC 400MG/16ML INJECTION with other drugs.

What should I tell my doctor before taking CROGNOC 400MG/16ML INJECTION?Arrow

It is vital to inform your physician before taking CROGNOC 400MG/16ML INJECTION if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to CROGNOC 400MG/16ML INJECTION or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

What is Bevacizumab and how is it used in CROGNOC 400MG/16ML INJECTION?Arrow

Bevacizumab is molecule/combination used for making CROGNOC 400MG/16ML INJECTION.

For what types of oncology is CROGNOC 400MG/16ML INJECTION used to treat?Arrow

CROGNOC 400MG/16ML INJECTION is prescribed for Oncology ailments/diseases/conditions.

Can CROGNOC 400MG/16ML INJECTION cure cancer?Arrow

CROGNOC 400MG/16ML INJECTION is prescribed for Oncology ailments/diseases/conditions.

References

Book Icon

Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group,Bevacizumab Injection, Indication

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Ratings & Review

It's good work and always best treatment and every time attend coustomer properly and perfectly

Shraddha Landge

•

Reviewed on 23-01-2024

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(5/5)

Excellent 👍👍👍

ashok badhala

•

Reviewed on 26-11-2022

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(5/5)

Proper medicine at big saving rate

Mukesh Jain

•

Reviewed on 24-01-2024

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(5/5)

Should display more medical verities.

Ronak Ankola

•

Reviewed on 25-07-2023

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(2/5)

Good service , great discount, I am regular customer

Gohil Aadityaraj

•

Reviewed on 27-07-2023

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(5/5)

Marketer / Manufacturer Details

CELON LABORATORIES LTD

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India

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CROGNOC 400MG/16ML INJECTION

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