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DAPLO M 10MG TABLET 10'S

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DAPLO M 10MG TABLET 10'S

By DR REDDY'S LABORATORIES LIMITED

MRP

205.5

₹174.68

15 % OFF

₹17.47 Only /

Tablet

10

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About DAPLO M 10MG TABLET 10'S

  • DAPLO M 10MG TABLET 10'S is a combination medicine specifically designed to manage blood sugar levels in adults with type 2 diabetes. It combines two powerful active ingredients: Dapagliflozin and Metformin. Dapagliflozin belongs to a class of drugs known as SGLT2 inhibitors, while Metformin is a biguanide.
  • Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. This allows excess glucose to be excreted through urine, effectively lowering blood sugar levels. Metformin, on the other hand, primarily reduces glucose production in the liver and improves the body's sensitivity to insulin, helping insulin work more effectively.
  • This dual-action approach makes DAPLO M 10MG TABLET 10'S highly effective in controlling blood sugar levels. It is typically prescribed when diet and exercise alone are not sufficient to achieve adequate glycemic control. By lowering blood sugar, DAPLO M 10MG TABLET 10'S helps reduce the risk of serious complications associated with diabetes, such as kidney damage, nerve problems, vision loss, and heart disease.
  • DAPLO M 10MG TABLET 10'S is usually taken once or twice daily with meals, as directed by your doctor. It's crucial to follow your doctor's instructions carefully and maintain a healthy lifestyle, including a balanced diet and regular exercise, to maximize the benefits of this medication. Regular monitoring of blood sugar levels is also essential to ensure optimal management of your diabetes. Always consult your healthcare provider for personalized medical advice and treatment.

Uses of DAPLO M 10MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing the risk of heart disease (in some patients)
  • Slowing the progression of kidney disease (in some patients)
  • Assist in weight management in obese patients

How DAPLO M 10MG TABLET 10'S Works

  • DAPLO M 10MG TABLET 10'S is a combination medication containing Dapagliflozin and Metformin, designed to manage blood sugar levels in adults with type 2 diabetes. It works through complementary mechanisms of action to achieve optimal glycemic control.
  • Dapagliflozin, a key component of DAPLO M, belongs to a class of drugs known as Sodium-Glucose Co-transporter 2 (SGLT2) inhibitors. SGLT2 is a protein found in the kidneys that plays a crucial role in reabsorbing glucose back into the bloodstream. By inhibiting SGLT2, Dapagliflozin reduces the reabsorption of glucose, allowing excess glucose to be excreted through urine. This process effectively lowers blood sugar levels without relying on insulin secretion. Consequently, it minimizes the risk of hypoglycemia (low blood sugar) when used alone. The elimination of glucose through urine also contributes to a modest calorie loss, which can aid in weight management.
  • Metformin, the other active ingredient in DAPLO M, is a biguanide that works primarily by decreasing glucose production in the liver. The liver is a significant source of glucose, especially during fasting states. Metformin suppresses hepatic glucose production by inhibiting gluconeogenesis, the process by which the liver synthesizes glucose from non-carbohydrate sources. Additionally, Metformin enhances insulin sensitivity in peripheral tissues such as muscles and fat. This means that cells become more responsive to insulin, allowing them to take up glucose more efficiently from the bloodstream. Furthermore, Metformin slows down the absorption of glucose from the intestines after a meal, further contributing to lower postprandial (after-meal) blood sugar spikes.
  • When combined, Dapagliflozin and Metformin offer a synergistic effect in managing type 2 diabetes. Dapagliflozin reduces glucose reabsorption in the kidneys, while Metformin reduces glucose production in the liver and enhances insulin sensitivity. This dual action effectively lowers both fasting and postprandial blood sugar levels. Moreover, the combination may provide additional benefits such as weight management and a reduced risk of cardiovascular events, although these effects may vary among individuals.
  • It is crucial to take DAPLO M 10MG TABLET 10'S as prescribed by your healthcare provider, usually once or twice daily with meals, to minimize gastrointestinal side effects. Regular monitoring of blood sugar levels is essential to assess the effectiveness of the medication and adjust the dosage if necessary. Patients should also be aware of potential side effects, such as urinary tract infections, genital infections, and dehydration, associated with Dapagliflozin, and gastrointestinal issues like nausea, diarrhea, and abdominal discomfort associated with Metformin. Staying hydrated and following a balanced diet are important aspects of managing diabetes while taking DAPLO M 10MG TABLET 10'S.
  • In summary, DAPLO M 10MG TABLET 10'S effectively manages blood sugar levels in type 2 diabetes by combining the actions of Dapagliflozin, which promotes glucose excretion through the kidneys, and Metformin, which reduces glucose production in the liver and enhances insulin sensitivity. This dual mechanism provides comprehensive glycemic control and helps patients achieve their target blood sugar levels.

Side Effects of DAPLO M 10MG TABLET 10'SArrow

Common side effects of DAPLO M 10MG TABLET may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Heartburn, Headache, Dizziness, Weakness, Fatigue, Skin rash, Itching, Upper respiratory tract infection, Urinary tract infection, Genital infection (in both men and women), Increased thirst, Increased urination. Less common or rare side effects may include: Hypoglycemia (low blood sugar), Ketoacidosis, Dehydration, Kidney problems, Liver problems, Pancreatitis, Angioedema (swelling of the face, lips, tongue, or throat), Allergic reactions, Bone fractures, Fournier's gangrene (a rare but serious infection of the genitals), Changes in cholesterol levels, Anemia. This is not an exhaustive list. Consult your doctor or pharmacist for a complete list and if you experience any unusual symptoms while taking DAPLO M 10MG TABLET.

Safety Advice for DAPLO M 10MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Daplo M if you are allergic to it.

Dosage of DAPLO M 10MG TABLET 10'SArrow

  • The recommended dosage of 'DAPLO M 10MG TABLET 10'S' varies depending on individual patient factors, including the severity of your condition, other medications you are taking, and your response to treatment. It is crucial to adhere to your doctor's specific instructions regarding dosage and timing. Typically, 'DAPLO M 10MG TABLET 10'S' is taken once daily, preferably in the morning. Your doctor may start you on a low dose and gradually increase it as needed to achieve the desired blood sugar control. Do not exceed the prescribed dose. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. Consistent timing of the dose each day helps maintain stable blood sugar levels and maximizes the effectiveness of the medication.
  • It's important to understand that 'DAPLO M 10MG TABLET 10'S' is most effective when combined with a healthy diet and regular exercise. Continue to follow your doctor's recommendations for diet and exercise while taking this medication. Regular monitoring of your blood sugar levels is also essential to ensure that the medication is working properly and to adjust the dosage as needed. Your doctor will advise you on how often to check your blood sugar and what target ranges to aim for. Furthermore, it’s highly advisable to have routine checkups with your physician to monitor your overall health and assess the effectiveness of 'DAPLO M 10MG TABLET 10'S'.
  • Take 'DAPLO M 10MG TABLET 10'S' only as per the prescription by your physician only. If you experience any side effects, such as nausea, diarrhea, or abdominal pain, consult your doctor immediately. Do not stop taking 'DAPLO M 10MG TABLET 10'S' without first talking to your doctor, as this could lead to a sudden increase in your blood sugar levels. Dosage adjustments should only be made under the supervision of a healthcare professional.

What if I miss my dose of DAPLO M 10MG TABLET 10'S?Arrow

  • If you miss a dose of DAPLO M 10MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store DAPLO M 10MG TABLET 10'S?Arrow

  • Keep DAPLO M 10MG TAB 1X10 away from the reach of children and pets.
  • Store DAPLO M 10MG TAB 1X10 at room temperature.

Benefits of DAPLO M 10MG TABLET 10'SArrow

  • DAPLO M 10MG TABLET 10'S is a combination medicine primarily used to manage type 2 diabetes mellitus. Its benefits are multifaceted, targeting various aspects of glucose control and overall metabolic health.
  • One of the primary benefits of DAPLO M is its dual mechanism of action. It combines dapagliflozin, an SGLT2 inhibitor, with metformin, a biguanide. Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood, thus increasing glucose excretion through urine. Metformin, on the other hand, reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues. This synergistic effect helps in achieving better glycemic control compared to using either medication alone.
  • Improved Glycemic Control: By reducing glucose reabsorption and hepatic glucose production, DAPLO M effectively lowers both fasting and postprandial blood glucose levels. This is crucial for preventing long-term complications associated with hyperglycemia, such as neuropathy, nephropathy, and retinopathy.
  • Weight Management: Dapagliflozin's mechanism of action leads to the excretion of excess glucose in the urine, which results in a loss of calories. This can contribute to modest weight loss in some patients, offering an additional benefit for individuals with type 2 diabetes who are often overweight or obese. Weight loss can further improve insulin sensitivity and overall metabolic health.
  • Blood Pressure Reduction: Studies have shown that SGLT2 inhibitors like dapagliflozin can have a mild diuretic effect, which can lead to a reduction in blood pressure. This is particularly beneficial for diabetic patients who often have co-existing hypertension. Lowering blood pressure reduces the risk of cardiovascular events.
  • Cardiovascular Benefits: Emerging evidence suggests that dapagliflozin may offer cardiovascular benefits beyond glucose control. Clinical trials have indicated a potential reduction in the risk of heart failure and major adverse cardiovascular events (MACE) in patients treated with dapagliflozin. This makes DAPLO M a valuable option for diabetic patients with or at high risk of cardiovascular disease.
  • Renal Protection: Some studies suggest that SGLT2 inhibitors like dapagliflozin may have a protective effect on the kidneys, slowing the progression of diabetic kidney disease. This is particularly important for patients with diabetes, as nephropathy is a common and serious complication.
  • Convenience of Combination Therapy: DAPLO M combines two medications into a single tablet, which simplifies the treatment regimen and can improve patient adherence. This is especially important for individuals who may have difficulty managing multiple medications.
  • Reduced Risk of Hypoglycemia: When used as monotherapy, metformin and dapagliflozin have a relatively low risk of causing hypoglycemia (low blood sugar). However, when used in combination with other diabetes medications, such as insulin or sulfonylureas, the risk of hypoglycemia may increase, so careful monitoring is necessary.
  • Improved Lipid Profile: Some studies have shown that dapagliflozin may lead to modest improvements in lipid profiles, such as a reduction in triglycerides and an increase in HDL cholesterol (the 'good' cholesterol). This can contribute to overall cardiovascular health.
  • Overall, DAPLO M 10MG TABLET 10'S offers a comprehensive approach to managing type 2 diabetes by addressing multiple aspects of the disease, including glycemic control, weight management, blood pressure, and cardiovascular risk. Its dual mechanism of action and convenient once-daily dosing make it a valuable tool in the management of type 2 diabetes mellitus, ultimately improving patient outcomes and quality of life.

How to use DAPLO M 10MG TABLET 10'SArrow

  • DAPLO M 10MG TABLET 10'S is an oral medication used to manage blood sugar levels in adults with type 2 diabetes. It is crucial to follow your doctor's instructions precisely regarding dosage and timing. Typically, this medication is taken once daily, preferably in the morning with food to minimize the risk of stomach upset.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. Consistency is key for optimal results; try to take it at the same time each day to maintain a steady level of medication in your bloodstream.
  • Before starting DAPLO M 10MG TABLET 10'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential interactions. Also, let your doctor know if you have any kidney or liver problems.
  • It's important to adhere to a healthy lifestyle while taking this medication. This includes following a balanced diet, engaging in regular physical activity, and monitoring your blood sugar levels as directed by your healthcare provider. Regular check-ups are essential to assess your progress and adjust the treatment plan if needed. If you experience any unusual side effects, such as severe stomach pain, nausea, or signs of an allergic reaction, seek immediate medical attention.
  • If you miss a dose of DAPLO M 10MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Quick Tips for DAPLO M 10MG TABLET 10'SArrow

  • **Prioritize Diet and Exercise:** DAPLO M 10MG TABLET 10'S works best when combined with a healthy diet and regular exercise. Focus on consuming a balanced diet low in processed foods, sugary drinks, and saturated fats. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. This synergistic approach helps improve blood sugar control and overall health more effectively than medication alone.
  • **Monitor Blood Sugar Regularly:** Keep a close watch on your blood sugar levels as directed by your doctor. Regular monitoring helps you understand how DAPLO M 10MG TABLET 10'S and your lifestyle choices are impacting your glucose levels. Share these readings with your healthcare provider, who can then adjust your treatment plan if needed. This proactive approach is vital for managing diabetes effectively and preventing complications.
  • **Stay Hydrated:** Drink plenty of water throughout the day. Adequate hydration helps your kidneys function properly, which is especially important when taking medications like DAPLO M 10MG TABLET 10'S. Staying hydrated also supports overall metabolic function and helps regulate blood sugar levels. Aim for at least 8 glasses of water daily, adjusting for activity levels and climate.
  • **Be Aware of Hypoglycemia Symptoms:** DAPLO M 10MG TABLET 10'S can sometimes cause hypoglycemia (low blood sugar), especially when combined with other diabetes medications or if you skip meals. Learn to recognize the symptoms of hypoglycemia, such as shakiness, sweating, dizziness, and confusion. Always carry a quick source of sugar, like glucose tablets or fruit juice, to treat low blood sugar promptly.
  • **Follow Your Doctor's Instructions Carefully:** Take DAPLO M 10MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Adhering to the prescribed regimen is crucial for achieving optimal blood sugar control and minimizing the risk of side effects. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor or pharmacist.

Food Interactions with DAPLO M 10MG TABLET 10'SArrow

  • DAPLO M 10MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood sugar levels. Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of low blood sugar (hypoglycemia).

FAQs

What is DAPLO M 10MG TABLET 10'S used for?Arrow

DAPLO M 10MG TABLET 10'S is used to control high blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise alone are not effective enough in controlling blood sugar.

What are the active ingredients in DAPLO M 10MG TABLET 10'S?Arrow

DAPLO M 10MG TABLET 10'S contains two active ingredients: Dapagliflozin and Metformin.

What are the common side effects of DAPLO M 10MG TABLET 10'S?Arrow

Common side effects of DAPLO M 10MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is DAPLO M 10MG TABLET 10'S safe to use during pregnancy?Arrow

DAPLO M 10MG TABLET 10'S is not recommended for use during pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.

Should DAPLO M 10MG TABLET 10'S be taken with food?Arrow

It is recommended to take DAPLO M 10MG TABLET 10'S with food to minimize the chance of stomach upset.

What should I do if I miss a dose of DAPLO M 10MG TABLET 10'S?Arrow

If you miss a dose of DAPLO M 10MG TABLET 10'S, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Does DAPLO M 10MG TABLET 10'S cause weight gain?Arrow

DAPLO M 10MG TABLET 10'S is not likely to cause weight gain. Some patients may actually experience weight loss.

How should DAPLO M 10MG TABLET 10'S be stored?Arrow

Store DAPLO M 10MG TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children.

Can DAPLO M 10MG TABLET 10'S be taken with other medications?Arrow

DAPLO M 10MG TABLET 10'S can interact with other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.

What happens if I overdose on DAPLO M 10MG TABLET 10'S?Arrow

Overdosing on DAPLO M 10MG TABLET 10'S can lead to hypoglycemia (low blood sugar). Seek immediate medical attention if you think you have taken too much of the medicine.

Is DAPLO M 10MG TABLET 10'S harmful to the kidneys?Arrow

DAPLO M 10MG TABLET 10'S can affect kidney function. Patients with kidney disease should use it with caution and follow their doctor's advice.

Is DAPLO M 10MG TABLET 10'S harmful to the liver?Arrow

DAPLO M 10MG TABLET 10'S can affect liver function. Patients with liver disease should use it with caution and follow their doctor's advice.

Does DAPLO M 10MG TABLET 10'S cause dizziness?Arrow

DAPLO M 10MG TABLET 10'S can cause dizziness in some patients, especially when they first start taking it.

Is DAPLO M 10MG TABLET 10'S safe for children?Arrow

DAPLO M 10MG TABLET 10'S is not approved for use in children.

What are other brands of Dapagliflozin and Metformin?Arrow

Other brands of Dapagliflozin and Metformin include Xigduo XR, Xigluo, and various generic options.

References

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FDA - FARXIGA (dapagliflozin) tablets, for oral use. This is the official FDA label for Dapagliflozin.

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DrugBank - Dapagliflozin. DrugBank entry providing comprehensive chemical and pharmaceutical information on Dapagliflozin.

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European Medicines Agency (EMA) - Forxiga. European public assessment report (EPAR) for Forxiga, the brand name of dapagliflozin in Europe, providing detailed scientific information.

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PMC - Dapagliflozin: a review of its use in the treatment of type 2 diabetes mellitus. This is a research article on the clinical use of dapagliflozin.

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ScienceDirect - Dapagliflozin. This is a ScienceDirect topic page summarizing research related to dapagliflozin.

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amit sharma

Reviewed on 17-07-2023

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(5/5)

Good and cost effective medicines

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Reviewed on 15-02-2024

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Good pharmacy

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Reviewed on 20-08-2023

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(5/5)

Best medicines, Timing and behaviour is very good for human beings

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Reviewed on 07-08-2023

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(5/5)

वेरी गुड एक्सीलेंट

bhavtosh vyas

Reviewed on 31-01-2024

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(5/5)


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DR REDDY'S LABORATORIES LIMITED

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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