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DENURIL 60MG/ML INJECTION
DENURIL 60MG/ML INJECTION
By ALKEM LABORATORIES LIMITED
MRP
₹
8625
₹7500
13.04 % OFF
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Composition
Product Details
About DENURIL 60MG/ML INJECTION
- DENURIL 60MG/ML INJECTION contains the active medicine called Denosumab. This medicine is mainly used to treat weak and brittle bones, a condition known as osteoporosis. It's also given to help prevent serious bone problems like fractures or pain that can happen when certain types of cancer, such as multiple myeloma and other cancers that have spread to the bone, affect the bones. It is usually given as an injection under the skin.
- DENURIL 60MG/ML INJECTION works by targeting a specific protein in the body called RANK ligand. This protein is involved in the process where bone tissue is broken down. By blocking this protein, the injection helps to slow down bone loss and make bones stronger. Studies have clearly shown that it can significantly increase the amount of bone material (bone density), which greatly lowers the chance of broken bones, especially in women after menopause who have osteoporosis, and in patients dealing with bone loss caused by cancer. Doctors will usually keep a close eye on how well your kidneys are working, especially if you have moderate kidney problems.
- Like all medicines, DENURIL 60MG/ML INJECTION is not suitable for everyone. You should not use it if you have ever had an allergic reaction to Denosumab or any of the other ingredients. It's very important to make sure you are getting enough calcium and vitamin D, often through supplements recommended by your doctor, throughout your treatment. These nutrients are essential for bone health and help the medicine work effectively. DENURIL 60MG/ML INJECTION is not approved for use in children and teenagers under 18 years old because we don't have enough information about whether it is safe and works well in this age group. Special care is needed if you have a condition called hypoparathyroidism, where your body doesn't make enough parathyroid hormone, as this can affect calcium levels which need careful monitoring.
- During treatment with DENURIL 60MG/ML INJECTION, some people might experience side effects. Common ones can include pain in your back, arms, legs, or joints. You might also notice some redness, swelling, or bruising at the site where the injection was given. Less common but more serious side effects can occur, such as very low calcium levels in the blood (hypocalcemia), which might cause muscle cramps, spasms, or numbness. Although rare, a severe bone problem in the jaw (osteonecrosis of the jaw) has been reported; maintaining good oral hygiene and informing your dentist about your treatment are important steps to help prevent this. Also, some unusual bone fractures (atypical femur fractures) have been observed in rare cases with long-term use. Always discuss any concerns or unusual symptoms with your healthcare provider immediately. This medication must only be administered by a trained healthcare professional. Regular blood tests, especially to check calcium levels, are typically performed to monitor your health during treatment. Following your doctor's instructions precisely and attending all scheduled appointments are crucial for the best possible outcome and safety while using DENURIL 60MG/ML INJECTION.
Uses of DENURIL 60MG/ML INJECTION
- Management of severe bone thinning (osteoporosis).
- Preventing bone weakening caused by hormonal treatments for breast or prostate cancer.
- Treating multiple myeloma, a bone marrow cancer.
- Managing bone metastases (cancer spread to bones).
Side Effects of DENURIL 60MG/ML INJECTION
Like all medications, DENURIL 60MG/ML INJECTION can cause side effects, although not everyone who takes it will experience them.
Safety Advice for DENURIL 60MG/ML INJECTION
Pregnancy
Consult a DoctorThe safety of using DENURIL 60MG/ML INJECTION during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
Dosage of DENURIL 60MG/ML INJECTION
- DENURIL 60MG/ML INJECTION is a medicine that needs to be given as an injection by qualified healthcare professionals, such as doctors or nurses. You will not administer this injection yourself at home. The way this medicine is given, including the specific amount (dosage) and the total length of your treatment (duration), is not fixed or standard for everyone. It is a decision carefully made by your healthcare provider based on several important factors. These factors include your specific medical condition being treated, how severe your condition is, and how well your body responds to the medication once treatment begins. Your doctor will assess these elements to determine the precise dose that is right for you and how long you will need to receive the injections. It is crucial to follow your healthcare provider's instructions regarding the dosage and schedule exactly. Sometimes, the dosage may need to be adjusted during the course of treatment depending on your response, ensuring the medication is as effective and safe as possible for your individual needs. This personalized approach ensures you receive the optimal treatment.
How to store DENURIL 60MG/ML INJECTION?
- Keep DENURIL 60MG INJ 1ML away from the reach of children and pets.
- Store DENURIL 60MG INJ 1ML in a refrigerator (2 - 8°C). Do not freeze.
Benefits of DENURIL 60MG/ML INJECTION
- DENURIL 60MG/ML INJECTION provides substantial benefits for maintaining and improving bone health. Its primary therapeutic effects are focused on significantly reducing the risk of fractures, substantially increasing bone mineral density, and promoting overall skeletal integrity. The mechanism of action involves a targeted approach: it works by inhibiting bone resorption. This process, where old bone tissue is broken down, is crucial but can become excessive in conditions like osteoporosis. DENURIL 60MG/ML INJECTION specifically acts on RANK ligands, key signaling molecules that drive bone breakdown. By blocking these signals, the medication effectively slows down the removal of bone tissue, allowing bone formation processes to strengthen the existing structure.
- This leads to stronger bones and a significantly decreased likelihood of fractures, particularly important for individuals diagnosed with osteoporosis, both postmenopausal women and men, as well as those at high risk due to other medical conditions or treatments. Increasing bone mineral density is a critical outcome, as it's a direct indicator of bone strength and resilience. These combined therapeutic effects — reduced resorption, increased density, and strengthened structure — contribute profoundly to improved bone health. Ultimately, by preventing debilitating fractures, DENURIL 60MG/ML INJECTION helps patients maintain mobility, reduce pain, and enhance their overall quality of life and independence. It's a vital treatment option for managing severe bone loss and preventing its serious consequences.
How to use DENURIL 60MG/ML INJECTION
- DENURIL 60MG/ML INJECTION is administered directly into the body as an injection. This procedure is strictly carried out by qualified healthcare professionals, such as doctors or nurses, in a clinical setting. You should never attempt to self-administer this medication. The precise amount of DENURIL 60MG/ML INJECTION you receive, along with the length of your treatment course, is carefully determined by your healthcare provider. They will consider your specific medical condition, how well you are responding to the medication, your overall health, and other relevant factors. Following your doctor's prescribed dosage and schedule is crucial for the medication to be effective and to minimize potential risks. Injections are often chosen when a rapid effect is needed or when the medication isn't absorbed effectively when taken orally. Your healthcare provider will monitor your progress throughout the treatment.
FAQs
Can DENURIL 60MG/ML INJECTION be used in patients with a history of cancer?
DENURIL 60MG/ML INJECTION is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.
What Are the Side Effects of DENURIL 60MG/ML INJECTION?
DENURIL 60MG/ML INJECTION can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.
Can DENURIL 60MG/ML INJECTION be used in individuals with dental implants?
DENURIL 60MG/ML INJECTION use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess DENURIL 60MG/ML INJECTION's potential risks and benefits.
Can DENURIL 60MG/ML INJECTION be used in children and adolescents with osteoporosis?
DENURIL 60MG/ML INJECTION is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.
Can DENURIL 60MG/ML INJECTION be used as a treatment for osteoporosis in men?
Yes, DENURIL 60MG/ML INJECTION is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.
Can DENURIL 60MG/ML INJECTION be used in patients with kidney problems?
DENURIL 60MG/ML INJECTION is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.
Does DENURIL 60MG/ML INJECTION interact with other medications?
It is important to inform your doctor or pharmacist about all the medications you are currently taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements, as DENURIL 60MG/ML INJECTION may interact with them.
What important precautions should I take while using DENURIL 60MG/ML INJECTION?
Attend all scheduled appointments to monitor treatment. Inform your doctor about your medical history, including infections, liver or kidney disease, and allergies. Seek immediate medical attention for severe reactions. Calcium levels may be affected, so monitor levels and ensure adequate calcium and vitamin D intake. Pregnant/breastfeeding women should consult a doctor. Avoid vaccines during treatment. Maintain good oral hygiene and have regular dental exams due to the risk of jaw osteonecrosis.
What is the active ingredient in DENURIL 60MG/ML INJECTION?
The active ingredient in DENURIL 60MG/ML INJECTION is DENOSUMAB.
Can DENURIL 60MG/ML INJECTION be used for Arthritis?
DENURIL 60MG/ML INJECTION is primarily used to treat osteoporosis and prevent bone fractures. While bone health is related to conditions like arthritis, its primary approved uses are for bone density issues and certain cancers causing bone loss, not specifically for arthritis inflammation itself. Your doctor will determine if it's appropriate for your condition.
How does DENURIL 60MG/ML INJECTION (Denosumab) help treat osteoporosis?
DENURIL 60MG/ML INJECTION contains Denosumab, which is a monoclonal antibody. It works by targeting a protein called RANKL, which is involved in bone breakdown. By blocking RANKL, Denosumab reduces the activity of cells that break down bone, thus increasing bone density and reducing the risk of fractures in osteoporosis.
References
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Chirag Patel
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Reviewed on 01-02-2024
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Reviewed on 01-04-2024
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Service and prize is good
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Reviewed on 13-04-2024
(5/5)
Marketer / Manufacturer Details
ALKEM LABORATORIES LIMITED
Country of Origin -
India
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