GLYCINORM M 80MG TABLET 15'S

How GLYCINORM M 80MG TABLET 15'S Works

• GLYCINORM M 80MG TABLET is a combination medication containing Gliclazide and Metformin, designed to manage type 2 diabetes mellitus. It works through complementary mechanisms to effectively lower blood glucose levels. Gliclazide, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the bloodstream into cells, where it's used for energy. By increasing insulin secretion, Gliclazide helps reduce blood sugar levels, particularly after meals.
• Metformin, a biguanide, works primarily by decreasing glucose production in the liver. It reduces the amount of glucose released into the bloodstream, preventing excessive blood sugar spikes. Additionally, Metformin improves insulin sensitivity, allowing cells to use insulin more effectively. This means that even the insulin that is already present in the body can work better to lower blood sugar levels.
• The combination of Gliclazide and Metformin provides a dual-pronged approach to managing blood sugar. Gliclazide addresses the issue of insufficient insulin release, while Metformin tackles excessive glucose production and insulin resistance. This synergistic effect helps to achieve better blood sugar control than either medication could achieve on its own. Regular monitoring of blood glucose levels is crucial while taking GLYCINORM M 80MG TABLET to ensure the medication is working effectively and to adjust the dosage as needed. It's important to use this medication in conjunction with diet and exercise as prescribed by your doctor.
• Specifically, Gliclazide binds to sulfonylurea receptors on pancreatic beta cells, leading to the closure of ATP-sensitive potassium channels. This depolarization of the cell membrane triggers an influx of calcium ions, which in turn stimulates the release of insulin-containing granules. Metformin, on the other hand, activates AMP-activated protein kinase (AMPK), a key regulator of glucose metabolism. Activation of AMPK in the liver reduces gluconeogenesis (the production of glucose from non-carbohydrate sources) and increases glucose uptake in peripheral tissues such as muscle. The combined action ensures a comprehensive approach to glycemic control, targeting both insulin secretion and insulin sensitivity.
• Patients taking GLYCINORM M 80MG TABLET should be aware of potential side effects and interactions. Common side effects include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort, particularly at the start of treatment. Hypoglycemia (low blood sugar) is another potential side effect, especially if the medication is taken without food or in conjunction with other diabetes medications. It's crucial to follow the doctor's instructions regarding dosage and timing of meals. Furthermore, patients should inform their healthcare provider about all other medications they are taking, as certain drugs can interact with Gliclazide and Metformin, potentially affecting their efficacy or increasing the risk of side effects. Regular check-ups and blood tests are essential to monitor kidney function and overall health while on this medication.

Possible side effects of GLYCINORM M 80MG TABLET may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness. * **Uncommon:** Skin rash, itching, urticaria (hives), photosensitivity (increased sensitivity to sunlight), abnormal liver function tests. * **Rare:** Lactic acidosis (build-up of lactic acid in the blood), vitamin B12 deficiency, anemia, jaundice, allergic reactions. * **Very Rare:** Severe allergic reactions (anaphylaxis), liver problems (hepatitis, liver failure), blood disorders (thrombocytopenia, leukopenia, agranulocytosis). **Important Note:** This is not an exhaustive list. If you experience any unusual or severe side effects, stop taking GLYCINORM M 80MG TABLET and consult your doctor immediately.

• If you miss a dose of GLYCINORM M 80MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep GLYCINORM M 80MG TAB 1X15 away from the reach of children and pets.
• Store GLYCINORM M 80MG TAB 1X15 at room temperature.

• Take GLYCINORM M 80MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them. Consistent adherence to the prescribed regimen is crucial for managing your blood sugar levels effectively. This ensures the medication works optimally to keep your glucose within the target range and prevents potential complications associated with fluctuating blood sugar.
• GLYCINORM M 80MG TABLET 15'S is most effective when taken with meals. This helps to control the rise in blood sugar that occurs after eating. Taking it at the same time each day, preferably with breakfast or your first main meal, will help you remember to take it regularly and maximize its benefits. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule.
• Monitor your blood sugar levels regularly as directed by your doctor while taking GLYCINORM M 80MG TABLET 15'S. Keeping a log of your readings can help you and your doctor track how well the medication is working and make any necessary adjustments to your treatment plan. Regular monitoring also allows you to identify and address any potential issues, such as hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar), promptly.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting GLYCINORM M 80MG TABLET 15'S. Certain medications can interact with GLYCINORM M, potentially affecting its efficacy or increasing the risk of side effects. It's especially important to discuss any blood thinners, heart medications, or other diabetes medications you are taking. This will help your doctor make informed decisions about your treatment plan and minimize potential drug interactions.
• Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity while taking GLYCINORM M 80MG TABLET 15'S. This medication works best when combined with lifestyle modifications. A balanced diet that is low in sugar and processed foods, along with regular exercise, can help improve your body's response to insulin and lower your blood sugar levels. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Always consult your doctor before starting any new exercise program.