SITABITE M 100/500MG TABLET 10'S

How SITABITE M 100/500MG TABLET 10'S Works

• SITABITE M 100/500MG TABLET 10'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Sitagliptin and Metformin, each working through different mechanisms to achieve optimal glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine throughout the day and especially after meals. These hormones stimulate the pancreas to release insulin and also reduce the secretion of glucagon from the pancreas. Glucagon is a hormone that raises blood sugar levels. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This results in increased insulin release when blood sugar is high and decreased glucagon secretion, ultimately helping to lower blood sugar levels after meals and throughout the day. Sitagliptin's action is glucose-dependent, meaning it primarily works when blood sugar is elevated, reducing the risk of hypoglycemia (low blood sugar).
• Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver. The liver is a major source of glucose in the body, and in individuals with type 2 diabetes, the liver often produces excessive amounts of glucose. Metformin reduces this hepatic glucose production through several mechanisms, including inhibiting gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscle and fat. This means that the body's cells become more responsive to insulin, allowing them to take up glucose from the bloodstream more effectively. Metformin may also slow down the absorption of glucose from the intestines into the bloodstream after a meal.
• In summary, SITABITE M 100/500MG TABLET 10'S works by: 1) Sitagliptin increasing incretin hormone levels, leading to increased insulin release and decreased glucagon secretion in a glucose-dependent manner. 2) Metformin reducing glucose production in the liver and improving insulin sensitivity in peripheral tissues. This dual mechanism of action helps to effectively control blood sugar levels in individuals with type 2 diabetes, leading to improved glycemic control and reduced risk of diabetes-related complications. It is important to take SITABITE M 100/500MG TABLET 10'S as prescribed by your doctor and to follow their recommendations regarding diet and exercise to achieve the best possible results.
• The synergistic action of Sitagliptin and Metformin allows for better blood sugar control than either medication could achieve alone. This combination targets multiple pathways involved in glucose regulation, addressing both insulin deficiency and insulin resistance, which are key features of type 2 diabetes.

Common side effects of Sitabite M 100/500mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, constipation, weakness, and upper respiratory tract infection. Less common but potentially serious side effects include pancreatitis, severe allergic reactions (rash, itching, swelling), liver problems (yellowing of skin/eyes), and lactic acidosis (muscle cramps, difficulty breathing, stomach pain). Contact your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of SITABITE M 100/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep SITABITE M 100/500MG TAB 1X10 away from the reach of children and pets.
• Store SITABITE M 100/500MG TAB 1X10 at room temperature.

• Take SITABITE M 100/500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This ensures optimal blood sugar control and minimizes potential side effects. Consistent adherence to the prescribed regimen is crucial for managing your diabetes effectively.
• Swallow SITABITE M 100/500MG TABLET 10'S whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed into your body. Taking it whole ensures that the medication works as intended over the appropriate duration.
• Take SITABITE M 100/500MG TABLET 10'S with food to minimize the risk of stomach upset. This medication can sometimes cause nausea or discomfort if taken on an empty stomach. Pairing it with a meal or snack helps to reduce these gastrointestinal side effects, making it easier to tolerate the medication regularly.
• Monitor your blood sugar levels regularly as directed by your doctor, especially when starting SITABITE M 100/500MG TABLET 10'S. Keeping track of your blood sugar levels helps you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Regular monitoring is a key part of effective diabetes management.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting SITABITE M 100/500MG TABLET 10'S. Certain medications can interact with this drug, potentially affecting its effectiveness or increasing the risk of side effects. Providing a complete list of your current medications helps your doctor ensure that SITABITE M 100/500MG TABLET 10'S is safe and appropriate for you.

• SITABITE M 100/500MG TABLET 10'S should be taken with food to avoid stomach upset. Consistent timing with meals is recommended to maintain stable blood sugar levels. Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis and interfere with blood sugar control. High-fat meals may delay the absorption of the medication. Consult your doctor or pharmacist for specific dietary advice related to this medication.