SITAHENZ DM 500MG TABLET 10'S

How SITAHENZ DM 500MG TABLET 10'S Works

• SITAHEANZ DM 500MG TABLET 10'S is a combination medicine containing two active ingredients: Sitagliptin and Metformin. These work together through distinct mechanisms to control blood sugar levels in individuals with type 2 diabetes.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine throughout the day and especially after meals. These hormones increase insulin release from the pancreas and decrease glucagon secretion from the alpha cells of the pancreas. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This results in more insulin being released when blood sugar is high (e.g., after meals) and less glucagon being released, which reduces glucose production by the liver. Therefore, sitagliptin works in a glucose-dependent manner, meaning it primarily affects blood sugar when levels are elevated, reducing the risk of hypoglycemia (low blood sugar).
• Metformin, on the other hand, is a biguanide. It works primarily by decreasing glucose production in the liver (hepatic glucose output). It does this by suppressing gluconeogenesis, the process by which the liver makes glucose from non-carbohydrate sources. Metformin also improves insulin sensitivity in peripheral tissues, such as muscles, allowing cells to use glucose more effectively. This means that cells are better able to take up glucose from the bloodstream, lowering blood sugar levels. Additionally, metformin slows down the absorption of glucose from the intestines after meals. Metformin does not stimulate insulin release, so it doesn't usually cause hypoglycemia when used alone.
• In summary, SITAHEANZ DM 500MG combines the effects of Sitagliptin, which enhances the action of incretin hormones to increase insulin release and reduce glucagon secretion, with Metformin, which reduces glucose production in the liver and improves insulin sensitivity. By addressing multiple pathways involved in blood sugar control, this combination medication provides more effective management of type 2 diabetes than either medication alone. It's important to take this medication as prescribed by your doctor and to follow their recommendations for diet and exercise to achieve optimal blood sugar control.
• The combined action of Sitagliptin and Metformin helps to maintain stable blood sugar levels throughout the day, reducing the risk of both hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Regular monitoring of blood sugar levels is essential to ensure the medication is working effectively and to adjust the dosage if needed, under the guidance of a healthcare professional.

Like all medicines, SITAHENZ DM 500MG TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Diarrhea * Stomach pain * Loss of appetite * Metallic taste * Headache * Hypoglycemia (low blood sugar) - especially when used with other diabetes medications like sulfonylureas or insulin. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Skin rash * Itching **Rare Side Effects (may affect up to 1 in 1,000 people):** * Lactic acidosis (build-up of lactic acid in the blood) – symptoms can include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat. **This is a serious side effect and requires immediate medical attention.** **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Abnormal liver function tests * Hepatitis (liver inflammation) * Urticaria (hives) * Erythema (skin redness) * Pancreatitis (inflammation of the pancreas) – symptoms can include severe pain in the abdomen which may spread to your back. * Vitamin B12 deficiency **Side effects where frequency is not known:** * Upper respiratory tract infection * Sore throat * Runny nose * Constipation * Stevens-Johnson Syndrome (a serious skin reaction)

• If you miss a dose of SITAHENZ DM 500MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITAHENZ DM 500MG TAB 1X10 away from the reach of children and pets.
• Store SITAHENZ DM 500MG TAB 1X10 at room temperature.

• Take SITAHENZ DM 500MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider. Consistency is key to managing your blood sugar levels effectively.
• SITAHENZ DM 500MG TABLET 10'S is most effective when taken with meals. This helps to control the rise in blood sugar that typically occurs after eating. Follow your doctor's instructions regarding the timing of your doses in relation to your meals.
• While taking SITAHENZ DM 500MG TABLET 10'S, it's crucial to maintain a healthy lifestyle. This includes following a balanced diet, engaging in regular physical activity, and managing your weight. These habits work synergistically with the medication to improve blood sugar control and overall health.
• Be aware of the potential side effects of SITAHENZ DM 500MG TABLET 10'S. Common side effects may include nausea, diarrhea, or stomach upset. If you experience persistent or severe side effects, contact your doctor promptly. Do not ignore any unusual symptoms.
• Regularly monitor your blood sugar levels as directed by your doctor. Keeping a record of your blood sugar readings can help you and your healthcare provider assess how well SITAHENZ DM 500MG TABLET 10'S is working for you and make any necessary adjustments to your treatment plan. This will enable you to proactively manage your condition.
• Store SITAHENZ DM 500MG TABLET 10'S at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Proper storage ensures the medication remains effective and safe to use. Don't store in the bathroom where moisture levels can be high.
• If you miss a dose of SITAHENZ DM 500MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one, as this can increase the risk of side effects.
• Before starting SITAHENZ DM 500MG TABLET 10'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Drug interactions can affect how SITAHENZ DM 500MG TABLET 10'S works and increase the risk of side effects. Be transparent with your healthcare provider about your complete medication list.

• SITAHENZ DM 500MG TABLET 10'S is generally safe to take with food. However, it's best to follow your doctor's instructions regarding when and how to take this medication. There are no known specific food items that are contraindicated while taking SITAHENZ DM 500MG TABLET 10'S.