SITANORM DM 500 TABLET 10'S
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SITANORM DM 500 TABLET 10'SSITANORM DM 500 TABLET 10'SSITANORM DM 500 TABLET 10'S
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SITANORM DM 500 TABLET 10'S

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SITANORM DM 500 TABLET 10'S

By MICRO LABS LIMITED

MRP

217.3

₹184.7

15 % OFF

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About SITANORM DM 500 TABLET 10'S

  • SITANORM DM 500 TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. This medication contains two active ingredients: Sitagliptin and Metformin.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the amount of insulin your body releases after a meal and decreasing the amount of sugar your body makes. Metformin, on the other hand, is a biguanide. It works by reducing glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.
  • By combining these two medications, SITANORM DM 500 TABLET 10'S offers a comprehensive approach to managing blood sugar levels. It helps to lower both fasting and post-meal blood sugar, reducing the risk of long-term complications associated with diabetes, such as kidney damage, nerve problems, loss of limbs, sexual function problems, and eye damage. It is important to use SITANORM DM 500 TABLET 10'S exactly as prescribed by your doctor, along with a healthy diet and regular exercise program, to achieve optimal results.
  • Always consult with your healthcare provider for personalized advice and to determine if SITANORM DM 500 TABLET 10'S is right for you. Discuss any existing medical conditions or medications you are currently taking to avoid potential drug interactions. Regular monitoring of blood sugar levels is also essential while taking this medication.

Uses of SITANORM DM 500 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Controls high blood sugar levels
  • Improves insulin sensitivity
  • Lowers post-meal blood sugar levels
  • Management of insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)

How SITANORM DM 500 TABLET 10'S Works

  • SITANORM DM 500 TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It contains two active ingredients: Sitagliptin and Metformin.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the levels of incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1), are released by the intestine throughout the day and especially after meals. These hormones play a crucial role in regulating blood sugar levels. Sitagliptin prevents the breakdown of these incretin hormones, prolonging their activity. By increasing incretin levels, Sitagliptin stimulates the pancreas to release insulin when blood sugar is high (e.g., after a meal) and reduces the amount of glucose produced by the liver when blood sugar is low. This helps to improve blood sugar control without the increased risk of hypoglycemia (low blood sugar) that can occur with some other diabetes medications.
  • Metformin, on the other hand, is a biguanide. It works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Specifically, Metformin reduces hepatic glucose production by inhibiting gluconeogenesis (the process by which the liver makes glucose from non-carbohydrate sources). It also enhances insulin sensitivity in muscle tissue, allowing cells to utilize glucose more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines into the bloodstream. Metformin does not stimulate insulin release; therefore, it carries a lower risk of causing hypoglycemia when used alone.
  • The combination of Sitagliptin and Metformin in SITANORM DM 500 TABLET 10'S offers a dual approach to managing blood sugar levels. Sitagliptin enhances insulin secretion and reduces glucagon secretion in a glucose-dependent manner, while Metformin reduces hepatic glucose production and improves insulin sensitivity. Together, they provide comprehensive glycemic control for individuals with type 2 diabetes.
  • By improving blood sugar control, SITANORM DM 500 TABLET 10'S helps to reduce the risk of long-term complications associated with diabetes, such as heart disease, kidney disease, nerve damage, and vision problems. However, it is important to note that SITANORM DM 500 TABLET 10'S should be used as part of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring of blood sugar levels. Patients should follow their healthcare provider's instructions carefully and report any side effects or concerns promptly.

Side Effects of SITANORM DM 500 TABLET 10'SArrow

SITANORM DM 500 TABLET 10'S, like other medications, can cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, stomach upset, and loss of appetite. Some individuals might experience hypoglycemia (low blood sugar), especially when taken with other diabetes medications like insulin or sulfonylureas. Symptoms of hypoglycemia include sweating, shaking, rapid heartbeat, dizziness, and confusion. Less common but potentially serious side effects can include pancreatitis (inflammation of the pancreas), characterized by severe abdominal pain that may radiate to the back, and allergic reactions, such as rash, itching, swelling, or difficulty breathing. Kidney problems have also been reported rarely. It's important to contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for SITANORM DM 500 TABLET 10'SArrow

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Allergies

Allergies

Do not use SITANORM DM 500 TABLET 10'S if you are allergic to sitagliptin or metformin.

Dosage of SITANORM DM 500 TABLET 10'SArrow

  • The recommended dosage of SITANORM DM 500 TABLET 10'S varies depending on individual patient needs, pre-existing medical conditions, and response to treatment. Your physician will determine the most appropriate dosage for you. Typically, the starting dose is one tablet taken orally, once or twice daily. This may be adjusted by your doctor based on your blood glucose levels and overall health. The maximum daily dose should not exceed the amount prescribed by your doctor.
  • SITANORM DM 500 TABLET 10'S should be swallowed whole with a glass of water and should not be crushed, chewed, or broken. It is generally recommended to take this medication with meals to minimize potential gastrointestinal side effects. Consistency in timing is crucial; try to take it at the same time(s) each day to maintain stable blood glucose levels.
  • It is essential to adhere strictly to the dosage and administration instructions provided by your healthcare provider. Do not alter the dosage or discontinue the medication without consulting your doctor. Regular monitoring of blood glucose levels is necessary to assess the effectiveness of the treatment and to make any necessary dosage adjustments. Your doctor may also recommend periodic blood tests to monitor kidney function and other relevant health parameters while you are taking SITANORM DM 500 TABLET 10'S.
  • If you miss a dose of SITANORM DM 500 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always consult with your healthcare provider if you have any questions or concerns regarding your dosage or medication schedule. Take 'SITANORM DM 500 TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of SITANORM DM 500 TABLET 10'S?Arrow

  • If you miss a dose of SITANORM DM 500 TABLET, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store SITANORM DM 500 TABLET 10'S?Arrow

  • Keep SITANORM DM 500MG TAB 1X10 away from the reach of children and pets.
  • Store SITANORM DM 500MG TAB 1X10 at room temperature.

Benefits of SITANORM DM 500 TABLET 10'SArrow

  • SITANORM DM 500 TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls high blood sugar levels, preventing serious complications such as kidney damage, blindness, nerve problems, loss of limbs, and sexual function issues. By managing blood sugar, it reduces the risk of heart attack or stroke.
  • This medication promotes better blood sugar control by increasing insulin secretion from the pancreas and decreasing glucose production by the liver. Simultaneously, it enhances the body's response to insulin. Consistent use, alongside a healthy diet and regular exercise, dramatically improves overall health and quality of life for individuals with type 2 diabetes.
  • SITANORM DM 500 TABLET 10'S offers several key benefits in managing type 2 diabetes. Firstly, it significantly lowers HbA1c levels, a measure of average blood sugar over the past 2-3 months, indicating improved long-term glycemic control. Secondly, it reduces fasting and post-meal blood sugar spikes, preventing hyperglycemia and its associated symptoms like frequent urination, excessive thirst, and fatigue. Thirdly, the combination of sitagliptin and metformin works synergistically, addressing multiple pathways involved in blood sugar regulation for more comprehensive control.
  • Furthermore, SITANORM DM 500 TABLET 10'S is often well-tolerated, with a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications. It is also available in various strengths, allowing for individualized dosing based on patient needs and tolerance. The convenience of a single tablet combining two medications improves adherence and simplifies the treatment regimen. Finally, by effectively managing blood sugar, SITANORM DM 500 TABLET 10'S contributes to the prevention of long-term complications of diabetes, such as cardiovascular disease, neuropathy, nephropathy, and retinopathy, ultimately enhancing the patient's overall health and well-being. Regular monitoring by a healthcare professional is crucial to ensure optimal dosage and to monitor for any potential side effects.

How to use SITANORM DM 500 TABLET 10'SArrow

  • SITANORM DM 500 TABLET 10'S is an oral medication that combines two active ingredients to help manage blood sugar levels in individuals with type 2 diabetes. To maximize its effectiveness and minimize potential side effects, it's crucial to adhere to your doctor's instructions regarding dosage and timing. Generally, SITANORM DM 500 is taken once or twice daily, usually with meals. Taking it with food can significantly reduce the likelihood of experiencing an upset stomach, a common side effect of metformin, one of the active ingredients.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system and potentially alter its efficacy. Consistency is key when taking SITANORM DM 500. Try to take it at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's important to understand that SITANORM DM 500 is most effective when used in conjunction with a healthy diet and regular exercise. Follow the dietary recommendations provided by your doctor or a registered dietitian. Regular physical activity helps your body use insulin more effectively and can improve blood sugar control. Keep all your scheduled appointments with your doctor and the laboratory. Your doctor may want to perform regular blood tests to monitor your blood sugar levels and kidney function while you are taking SITANORM DM 500. Do not stop taking SITANORM DM 500 without talking to your doctor. Suddenly stopping the medication can cause your blood sugar levels to rise.
  • Inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, as they may interact with SITANORM DM 500. Also, tell your doctor if you have any kidney or liver problems, heart disease, or any other medical conditions. Be aware of the symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, rapid heartbeat, and confusion. If you experience these symptoms, consume a quick source of sugar, such as glucose tablets or fruit juice, and seek medical attention if necessary.

Quick Tips for SITANORM DM 500 TABLET 10'SArrow

  • Take SITANORM DM 500 TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, as this could affect your blood sugar levels and overall health. Consistency is key for effective management of your diabetes.
  • It's best to take SITANORM DM 500 TABLET 10'S with meals to help prevent stomach upset and improve absorption. Try to take it at the same time each day to maintain a steady level of medication in your body. This routine will help in better glucose control throughout the day.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider while taking SITANORM DM 500 TABLET 10'S. Keep a record of your readings and share them with your doctor during your appointments. This helps them assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. Limit your intake of sugary and processed foods, and incorporate exercises like walking, swimming, or cycling into your daily routine. A healthy lifestyle complements the effects of SITANORM DM 500 TABLET 10'S and can improve your overall well-being.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times. If you experience these symptoms, consume the sugar source immediately and inform your doctor. Knowing how to manage hypoglycemia is crucial for your safety while on this medication.

Food Interactions with SITANORM DM 500 TABLET 10'SArrow

  • SITANORM DM 500 TABLET 10'S can be taken with or without food. However, it is advisable to take it at the same time each day to maintain consistent blood sugar levels. If you experience stomach upset, taking it with food might help.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of low blood sugar (hypoglycemia).

FAQs

What is SITANORM DM 500 TABLET 10'S?Arrow

SITANORM DM 500 TABLET 10'S is a combination of two medicines: Sitagliptin and Metformin. It is used to control high blood sugar levels in people with type 2 diabetes mellitus, when diet and exercise alone are not enough to control blood sugar.

How does SITANORM DM 500 TABLET 10'S work?Arrow

Sitagliptin, a DPP-4 inhibitor, works by increasing the release of insulin and decreasing the levels of glucagon. Metformin, a biguanide, works by decreasing the amount of glucose produced by the liver and improving the body's sensitivity to insulin.

What are the common side effects of SITANORM DM 500 TABLET 10'S?Arrow

Common side effects of SITANORM DM 500 TABLET 10'S include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is SITANORM DM 500 TABLET 10'S safe for people with kidney disease?Arrow

SITANORM DM 500 TABLET 10'S should be used with caution in people with kidney disease. The dosage may need to be adjusted based on kidney function. It is not recommended for people with severe kidney disease.

How to store SITANORM DM 500 TABLET 10'S?Arrow

Store SITANORM DM 500 TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children.

Is SITANORM DM 500 TABLET 10'S safe during pregnancy?Arrow

The safety of SITANORM DM 500 TABLET 10'S during pregnancy has not been established. Pregnant women should use it only if clearly needed and as directed by a doctor.

Is SITANORM DM 500 TABLET 10'S safe for breastfeeding women?Arrow

It is not known whether SITANORM DM 500 TABLET 10'S is excreted in breast milk. Breastfeeding women should consult their doctor before using it.

What to do if a dose of SITANORM DM 500 TABLET 10'S is missed?Arrow

If a dose of SITANORM DM 500 TABLET 10'S is missed, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time.

What are the symptoms of an overdose of SITANORM DM 500 TABLET 10'S?Arrow

Symptoms of an overdose of SITANORM DM 500 TABLET 10'S may include nausea, vomiting, abdominal pain, diarrhea, and lactic acidosis (buildup of lactic acid in the blood).

Can SITANORM DM 500 TABLET 10'S be taken with other medications?Arrow

SITANORM DM 500 TABLET 10'S can interact with certain other medications. Tell your doctor about all the medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements.

Does SITANORM DM 500 TABLET 10'S cause weight gain?Arrow

SITANORM DM 500 TABLET 10'S does not usually cause weight gain. However, in some people, it may increase appetite, which can lead to weight gain.

Can SITANORM DM 500 TABLET 10'S cause low blood sugar?Arrow

SITANORM DM 500 TABLET 10'S alone does not usually cause low blood sugar. However, if it is taken with other diabetes medications, such as insulin or sulfonylureas, the risk of low blood sugar may increase.

Can SITANORM DM 500 TABLET 10'S cause vitamin B12 deficiency?Arrow

Metformin, an ingredient in SITANORM DM 500 TABLET 10'S, can cause vitamin B12 deficiency with long-term use.

Should SITANORM DM 500 TABLET 10'S be taken with or without food?Arrow

SITANORM DM 500 TABLET 10'S is recommended to be taken with food to minimize the possibility of stomach upset.

Is it safe to consume alcohol while taking SITANORM DM 500 TABLET 10'S?Arrow

It is not recommended to consume alcohol while taking SITANORM DM 500 TABLET 10'S, as it can increase the risk of low blood sugar and also increase the risk of lactic acidosis.

References

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FDA Prescribing Information for Metformin Hydrochloride and Sitagliptin Tablets. This document provides detailed information on the drug's clinical pharmacology, indications, dosage, contraindications, warnings, precautions, adverse reactions, drug interactions, and use in specific populations.

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DrugBank entry for Sitagliptin. This entry provides comprehensive information on Sitagliptin, including its mechanism of action, pharmacokinetics, drug interactions, and therapeutic uses.

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DrugBank entry for Metformin. This entry provides comprehensive information on Metformin, including its mechanism of action, pharmacokinetics, drug interactions, and therapeutic uses.

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системные эффекты комбинированной терапии ситаглиптином и метформином на функцию β-клеток у пациентов с сахарным диабетом 2 типа: систематический обзор и метаанализ (Systematic effects of combined sitagliptin and metformin therapy on β-cell function in patients with type 2 diabetes: a systematic review and meta-analysis). PMC. [This study may contain relevant information on the combined effects of sitagliptin and metformin.]

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European Medicines Agency (EMA) - Januvia (sitagliptin) EPAR. Provides detailed scientific assessment and regulatory information for sitagliptin.

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National Institute for Health and Care Excellence (NICE) - Type 2 diabetes: management. Contains guidelines on the management of type 2 diabetes, including the use of metformin and sitagliptin.

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