SITAMER TRIO 100/10/500MG TABLET 15'S
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SITAMER TRIO 100/10/500MG TABLET 15'S

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SITAMER TRIO 100/10/500MG TABLET 15'S

By SYNOKEM PHARMACEUTICALS LTD

MRP

300

₹145

51.67 % OFF

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About SITAMER TRIO 100/10/500MG TABLET 15'S

  • SITAMER TRIO 100/10/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels in adults when diet and exercise alone are not enough. This tablet contains three active ingredients: Sitagliptin, Metformin, and Pioglitazone.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the release of insulin from the pancreas and decreasing the amount of sugar produced by the liver. Metformin is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity. Pioglitazone belongs to the thiazolidinedione class of drugs and works by increasing the body's sensitivity to insulin.
  • By combining these three medications, SITAMER TRIO provides a comprehensive approach to managing blood sugar levels. It helps to improve glycemic control, reduce the risk of diabetes-related complications, and improve overall health. It is important to take this medication as prescribed by your doctor and to follow a healthy diet and exercise plan.
  • This medication is typically taken orally, once or twice daily, with meals to reduce gastrointestinal side effects. Common side effects may include nausea, diarrhea, stomach upset, and headache. It is important to monitor blood sugar levels regularly while taking this medication and to inform your doctor of any unusual symptoms or side effects.
  • SITAMER TRIO 100/10/500MG TABLET is a prescription medication and should only be used under the guidance of a healthcare professional. It is not suitable for everyone, and your doctor will assess your individual needs and medical history before prescribing this medication. It is also important to inform your doctor about any other medications you are taking, as drug interactions may occur.

Uses of SITAMER TRIO 100/10/500MG TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • Managing insulin resistance associated with Polycystic Ovary Syndrome (PCOS) (off-label use)

How SITAMER TRIO 100/10/500MG TABLET 15'S Works

  • SITAMER TRIO 100/10/500MG TABLET 15'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: Sitagliptin, Dapagliflozin, and Metformin. Each component works through different mechanisms to lower blood sugar levels.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones released by the gut in response to food. These incretin hormones help to increase insulin release from the pancreas and decrease glucagon secretion from the liver. Insulin helps to move glucose from the blood into cells, where it can be used for energy. Glucagon signals the liver to release stored glucose into the blood. By increasing insulin and decreasing glucagon, sitagliptin helps to lower blood sugar levels, especially after meals.
  • Dapagliflozin is an SGLT2 inhibitor (sodium-glucose co-transporter 2 inhibitor). SGLT2 inhibitors work in the kidneys by preventing the reabsorption of glucose back into the bloodstream. Normally, the kidneys filter glucose from the blood and then reabsorb it, sending it back into the body. Dapagliflozin blocks this reabsorption, causing excess glucose to be excreted in the urine. This process lowers blood sugar levels and can also lead to modest weight loss and blood pressure reduction.
  • Metformin is a biguanide that works primarily by reducing glucose production in the liver. It also improves insulin sensitivity, allowing the body to use insulin more effectively. Metformin decreases the amount of glucose the liver releases into the bloodstream and helps muscle cells use insulin more efficiently. It is a cornerstone medication in the treatment of type 2 diabetes and is often the first medication prescribed upon diagnosis.
  • In summary, SITAMER TRIO 100/10/500MG TABLET 15'S works through three complementary mechanisms: Sitagliptin enhances insulin release and reduces glucagon secretion, Dapagliflozin increases glucose excretion through the kidneys, and Metformin reduces glucose production in the liver and improves insulin sensitivity. This triple-action approach provides comprehensive glycemic control for individuals with type 2 diabetes.
  • The combination of these three drugs helps in achieving better blood glucose control than any of the drugs alone. It is important to take this medication as prescribed by your doctor and in conjunction with diet and exercise.

Side Effects of SITAMER TRIO 100/10/500MG TABLET 15'SArrow

Common side effects of SITAMER TRIO 100/10/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, and weakness. Less common but potentially serious side effects can include lactic acidosis, pancreatitis, allergic reactions (rash, itching, swelling), liver problems (jaundice, dark urine), kidney problems, and vitamin B12 deficiency. Some patients may also experience constipation, bloating, flatulence, or changes in blood cell counts. It's important to contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for SITAMER TRIO 100/10/500MG TABLET 15'SArrow

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Dosage of SITAMER TRIO 100/10/500MG TABLET 15'SArrow

  • The recommended dosage of SITAMER TRIO 100/10/500MG TABLET 15'S varies depending on individual patient needs and response to treatment. It's crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Typically, this medication is taken orally, usually with meals, to minimize gastrointestinal discomfort and improve absorption. The usual starting dose may be one tablet once or twice daily, but your doctor will determine the most appropriate dosage regimen based on your blood glucose levels and overall health condition. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
  • The maximum daily dose should not exceed what your physician has prescribed. Consistency is key for optimal results. Try to take SITAMER TRIO 100/10/500MG TABLET 15'S at the same time(s) each day to maintain steady levels of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Regular monitoring of blood glucose levels is essential while taking SITAMER TRIO 100/10/500MG TABLET 15'S to assess its effectiveness and make any necessary dosage adjustments. Your doctor may also recommend periodic blood tests to monitor kidney function and other relevant parameters. It is very important to follow all the medical advice given to you by your healthcare provider. Take 'SITAMER TRIO 100/10/500MG TABLET 15'S' only as per the prescription by your physician only.

What if I miss my dose of SITAMER TRIO 100/10/500MG TABLET 15'S?Arrow

  • If you miss a dose of SITAMER TRIO 100/10/500MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store SITAMER TRIO 100/10/500MG TABLET 15'S?Arrow

  • Keep SITAMER TRIO 100/10/500MG TAB 1X15 away from the reach of children and pets.
  • Store SITAMER TRIO 100/10/500MG TAB 1X15 at room temperature.

Benefits of SITAMER TRIO 100/10/500MG TABLET 15'SArrow

  • SITAMER TRIO 100/10/500MG TABLET 15'S is a triple combination oral antidiabetic medication meticulously formulated to manage type 2 diabetes mellitus effectively. It combines the power of three active ingredients – Sitagliptin, Dapagliflozin, and Metformin – each working through distinct mechanisms to achieve comprehensive glycemic control. This multifaceted approach addresses various facets of the disease, ensuring a more holistic and targeted therapeutic outcome.
  • One of the primary benefits of SITAMER TRIO is its ability to significantly lower blood sugar levels. Sitagliptin, a DPP-4 inhibitor, enhances the levels of incretin hormones, which stimulate insulin release and reduce glucagon secretion, particularly after meals. Dapagliflozin, an SGLT2 inhibitor, promotes the excretion of glucose through urine, thereby reducing blood sugar. Metformin, a biguanide, decreases glucose production in the liver and improves insulin sensitivity in the body's tissues. Together, these components work synergistically to maintain optimal blood glucose levels throughout the day.
  • Beyond glycemic control, SITAMER TRIO offers additional cardiovascular benefits. Dapagliflozin has been shown to reduce the risk of heart failure and cardiovascular death in patients with type 2 diabetes and established cardiovascular disease. This makes SITAMER TRIO a valuable option for individuals with both diabetes and heart conditions, providing dual protection.
  • SITAMER TRIO can also contribute to weight management. Dapagliflozin's mechanism of action, which involves the removal of glucose through urine, results in a caloric loss that can lead to modest weight reduction. This is particularly beneficial for individuals with type 2 diabetes who are also struggling with obesity or overweight.
  • The convenience of SITAMER TRIO lies in its simplified dosing regimen. As a single tablet containing three medications, it reduces the pill burden for patients, improving adherence to the prescribed treatment plan. This is especially important for individuals managing multiple medications for various health conditions.
  • Moreover, SITAMER TRIO has been shown to improve HbA1c levels, a key indicator of long-term blood sugar control. By consistently lowering blood glucose, SITAMER TRIO helps patients achieve and maintain their target HbA1c levels, reducing the risk of long-term complications associated with diabetes, such as nerve damage, kidney disease, and vision problems.
  • SITAMER TRIO offers a comprehensive approach to managing type 2 diabetes by effectively lowering blood sugar levels, providing cardiovascular benefits, aiding in weight management, simplifying medication regimens, and improving long-term glycemic control. Always consult with your healthcare provider to determine if SITAMER TRIO is the right choice for your individual needs and to discuss potential risks and benefits.

How to use SITAMER TRIO 100/10/500MG TABLET 15'SArrow

  • SITAMER TRIO 100/10/500MG TABLET 15'S is an oral medication and should be taken as directed by your doctor. Typically, it is prescribed to be taken once or twice daily, preferably with meals to minimize gastrointestinal discomfort. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it. It is crucial to adhere to the prescribed dosage and duration of treatment, even if you start feeling better before the course is completed. Do not discontinue the medication without consulting your healthcare provider, as abruptly stopping it may lead to fluctuations in blood sugar levels.
  • Before starting SITAMER TRIO 100/10/500MG TABLET 15'S, inform your doctor about any pre-existing medical conditions, such as kidney or liver problems, heart disease, or any allergies. Also, disclose all other medications, supplements, or herbal products you are currently taking to avoid potential drug interactions. This medication is most effective when combined with a healthy diet and regular exercise. Monitor your blood sugar levels regularly as directed by your doctor and keep them informed of the results. If you experience any unusual side effects, such as severe abdominal pain, persistent nausea, or symptoms of hypoglycemia (low blood sugar), seek immediate medical attention.
  • Consistency is key for optimal results. Try to take SITAMER TRIO 100/10/500MG TABLET 15'S at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Store the medication in a cool, dry place, away from direct sunlight and moisture, and keep it out of reach of children.

Quick Tips for SITAMER TRIO 100/10/500MG TABLET 15'SArrow

  • Take SITAMER TRIO 100/10/500MG TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your healthcare provider. This medication is typically taken with meals to help reduce the risk of stomach upset and improve absorption of the drugs. It is crucial to adhere to the prescribed regimen for optimal blood sugar control. Consistency is key; try to take it at the same times each day to maintain steady medication levels in your body.
  • Monitor your blood sugar levels regularly while taking SITAMER TRIO 100/10/500MG TABLET 15'S. Keep a log of your readings to share with your doctor during check-ups. Regular blood glucose monitoring helps you and your doctor assess how well the medication is working and whether any adjustments to your treatment plan are needed. Pay attention to any patterns or trends in your blood sugar levels, and promptly report any significant changes or concerns to your healthcare provider.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting SITAMER TRIO 100/10/500MG TABLET 15'S. Drug interactions can affect how this medication works or increase the risk of side effects. Certain medications, such as diuretics, corticosteroids, and thyroid hormones, can affect blood sugar control. By providing a complete list of your medications, your doctor can assess potential interactions and make informed decisions about your treatment plan.
  • Be aware of the potential side effects of SITAMER TRIO 100/10/500MG TABLET 15'S. Common side effects may include nausea, diarrhea, headache, and dizziness. If you experience any bothersome or persistent side effects, consult your doctor. In rare cases, more serious side effects such as lactic acidosis or pancreatitis may occur. Seek immediate medical attention if you experience symptoms such as severe abdominal pain, persistent vomiting, difficulty breathing, or unexplained weakness. Prompt recognition and management of side effects can help minimize complications and ensure your safety.
  • Maintain a healthy lifestyle while taking SITAMER TRIO 100/10/500MG TABLET 15'S. Follow a balanced diet, engage in regular physical activity, and manage your weight. These lifestyle modifications can complement the effects of the medication and improve your overall health. A registered dietitian or certified diabetes educator can provide personalized guidance on diet and exercise. Additionally, avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of side effects. Regular follow-up appointments with your healthcare team are essential for monitoring your progress and adjusting your treatment plan as needed.

Food Interactions with SITAMER TRIO 100/10/500MG TABLET 15'SArrow

  • SITAMER TRIO 100/10/500MG TABLET 15'S may interact with certain foods or beverages. To maximize its effectiveness and minimize potential side effects, it is generally recommended to take this medication with food. Taking it with food can help to reduce the risk of stomach upset or gastrointestinal discomfort.
  • Avoid excessive alcohol consumption while taking SITAMER TRIO 100/10/500MG TABLET 15'S, as it may increase the risk of side effects such as low blood sugar (hypoglycemia) or liver problems.
  • Maintain a consistent carbohydrate intake while taking this medication. Irregular or drastically changed carbohydrate consumption may affect blood sugar control.
  • Consult your doctor or pharmacist for specific dietary advice tailored to your individual health condition and other medications you may be taking.

FAQs

What is Sitamer Trio 100/10/500mg Tablet used for?Arrow

Sitamer Trio 100/10/500mg Tablet is used to treat type 2 diabetes mellitus, especially when diet and exercise are not enough to control blood sugar levels adequately.

What are the main ingredients in Sitamer Trio 100/10/500mg Tablet?Arrow

Sitamer Trio 100/10/500mg Tablet contains three main ingredients: Sitagliptin, Dapagliflozin, and Metformin.

What are the common side effects of Sitamer Trio 100/10/500mg Tablet?Arrow

Common side effects of Sitamer Trio 100/10/500mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, and low blood sugar (hypoglycemia).

Is Sitamer Trio 100/10/500mg Tablet safe during pregnancy?Arrow

The safety of Sitamer Trio 100/10/500mg Tablet during pregnancy has not been established. It should only be used if the benefits outweigh the risks and under doctor's advice.

How should I store Sitamer Trio 100/10/500mg Tablet?Arrow

Store Sitamer Trio 100/10/500mg Tablet at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

Is Sitamer Trio 100/10/500mg Tablet safe for patients with kidney problems?Arrow

Patients with kidney problems should use Sitamer Trio 100/10/500mg Tablet with caution, as it can worsen kidney function. Dosage adjustment may be required.

Should Sitamer Trio 100/10/500mg Tablet be taken with or without food?Arrow

Sitamer Trio 100/10/500mg Tablet is generally recommended to be taken with food to minimize stomach upset.

Can Sitamer Trio 100/10/500mg Tablet interact with other medications?Arrow

Sitamer Trio 100/10/500mg Tablet can interact with certain other medications, such as insulin and some diuretics. Tell your doctor about all the medications you are taking.

What happens if I miss a dose of Sitamer Trio 100/10/500mg Tablet?Arrow

If you miss a dose of Sitamer Trio 100/10/500mg Tablet, take it as soon as you remember. If it is close to the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

How long does it take for Sitamer Trio 100/10/500mg Tablet to work?Arrow

It may take a few weeks for Sitamer Trio 100/10/500mg Tablet to start lowering blood sugar levels. It is important to take it regularly to see the full effect.

Does Sitamer Trio 100/10/500mg Tablet cause weight gain?Arrow

Sitamer Trio 100/10/500mg Tablet is not likely to cause weight gain, but it may happen in some patients.

Can I drink alcohol while taking Sitamer Trio 100/10/500mg Tablet?Arrow

Drinking alcohol while taking Sitamer Trio 100/10/500mg Tablet can increase the risk of low blood sugar and other side effects. It is advised to avoid alcohol.

What are the symptoms of an overdose of Sitamer Trio 100/10/500mg Tablet?Arrow

Symptoms of an overdose of Sitamer Trio 100/10/500mg Tablet may include severe low blood sugar, nausea, vomiting, and abdominal pain.

Can Sitamer Trio 100/10/500mg Tablet be stopped abruptly?Arrow

Sitamer Trio 100/10/500mg Tablet should not be stopped abruptly, as it can cause a rise in blood sugar levels. It should only be stopped under the advice of a doctor.

What is the price of Sitamer Trio 100/10/500mg Tablet?Arrow

The price of Sitamer Trio 100/10/500mg Tablet can vary depending on the brand, location, and pharmacy.

References

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DrugBank: Metformin. Provides detailed chemical and pharmacological information on Metformin, one of the ingredients in SITAMER TRIO.

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PMC: Efficacy and safety of sitagliptin in older patients with type 2 diabetes. Research article discussing the use of Sitagliptin, another ingredient.

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FDA Label: Simvastatin. Official prescribing information from the FDA about Simvastatin.

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ScienceDirect: Simvastatin - An overview. Provides a concise summary of Simvastatin's mechanism, uses, and potential side effects.

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EMA: Simvastatin. European Medicines Agency report on Simvastatin.

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Marketer / Manufacturer Details

SYNOKEM PHARMACEUTICALS LTD

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SITAMER TRIO 100/10/500MG TABLET 15'S

SITAMER TRIO 100/10/500MG TABLET 15'S

MRP

300

₹145

51.67 % OFF

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