SITASON DM 1000MG TABLET 10'S

How SITASON DM 1000MG TABLET 10'S Works

• SITASON DM 1000MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines two powerful active ingredients: Sitagliptin and Metformin. Understanding how each component works is crucial to appreciating the overall mechanism of action of this medication.
• **Sitagliptin: The DPP-4 Inhibitor** Sitagliptin belongs to a class of drugs called DPP-4 (dipeptidyl peptidase-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a vital role in regulating blood sugar levels. They are released from the gut in response to food intake and have several beneficial effects: * **Stimulate Insulin Release:** Incretins signal the pancreas to release insulin, but only when blood sugar levels are high. This glucose-dependent action reduces the risk of hypoglycemia (low blood sugar). * **Suppress Glucagon Secretion:** Incretins also suppress the release of glucagon, a hormone that raises blood sugar levels by signaling the liver to release stored glucose. By reducing glucagon secretion, incretins help lower blood sugar levels. Sitagliptin works by inhibiting the DPP-4 enzyme, which prevents the breakdown of incretin hormones. This increases the levels of active incretins in the body, leading to improved blood sugar control.
• **Metformin: The Biguanide** Metformin is a biguanide that works through several mechanisms to lower blood sugar levels: * **Reduces Hepatic Glucose Production:** Metformin primarily works by decreasing the amount of glucose produced by the liver. It inhibits gluconeogenesis, the process by which the liver makes glucose from non-carbohydrate sources. * **Increases Insulin Sensitivity:** Metformin enhances the sensitivity of peripheral tissues (such as muscles) to insulin. This means that cells are better able to take up glucose from the bloodstream in response to insulin. * **Slows Intestinal Glucose Absorption:** Metformin can also slightly reduce the absorption of glucose from the intestines after a meal.
• **Synergistic Action** By combining Sitagliptin and Metformin, SITASON DM 1000MG TABLET 10'S offers a dual approach to managing blood sugar levels. Sitagliptin enhances the body's own incretin system, promoting insulin release and suppressing glucagon secretion in a glucose-dependent manner. Metformin reduces glucose production by the liver and improves insulin sensitivity in peripheral tissues. This combination provides complementary effects, leading to better overall blood sugar control compared to using either medication alone. It is important to take SITASON DM 1000MG TABLET 10'S as prescribed by your doctor and to follow their recommendations for diet and exercise to achieve the best possible results in managing your type 2 diabetes.

Like all medicines, SITASON DM 1000MG TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Hypoglycemia (low blood sugar) when used with other diabetes medications **Uncommon Side Effects (may affect up to 1 in 100 people):** * Skin rash * Itching * Urticaria (hives) * Constipation * Flatulence * Heartburn **Rare Side Effects (may affect up to 1 in 1,000 people):** * Lactic acidosis (a serious metabolic problem) * Vitamin B12 deficiency **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Liver problems * Pancreatitis (inflammation of the pancreas) * Severe allergic reactions (anaphylaxis) **Frequency Not Known (cannot be estimated from the available data):** * Acute kidney injury * Bullous pemphigoid (a skin disorder that causes blisters) **Important Note:** This is not an exhaustive list. If you experience any troublesome or persistent side effects, stop taking SITASON DM 1000MG TABLET 10'S and consult your doctor immediately.

• If you miss a dose of SITASON DM 1000MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITASON DM 1000MG TAB 1X10 away from the reach of children and pets.
• Store SITASON DM 1000MG TAB 1X10 at room temperature.

• Take SITASON DM 1000MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once or twice daily with meals to help reduce gastrointestinal side effects. Consistent timing is crucial for maintaining stable blood sugar levels.
• Follow a balanced diet and exercise regularly while taking SITASON DM 1000MG TABLET 10'S. This medication works best when combined with lifestyle modifications. Focus on incorporating fiber-rich foods, lean proteins, and healthy fats into your diet. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• Monitor your blood sugar levels regularly, as directed by your doctor. Keep a record of your readings and share them with your healthcare provider during your appointments. This helps them to adjust your medication dosage as needed and assess the effectiveness of your treatment plan. Regular monitoring also allows you to identify and manage any potential fluctuations in your blood sugar.
• Be aware of the symptoms of low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia). Hypoglycemia symptoms may include shakiness, sweating, dizziness, and confusion. Hyperglycemia symptoms may include increased thirst, frequent urination, and blurred vision. Know how to manage these conditions and inform your family and friends about what to do in case of an emergency.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Some medications can interact with SITASON DM 1000MG TABLET 10'S, potentially affecting its effectiveness or increasing the risk of side effects. This includes over-the-counter medications, vitamins, and herbal remedies. A comprehensive list will help your doctor make informed decisions about your treatment plan.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration helps your body function properly and can also aid in managing blood sugar levels. Aim for at least eight glasses of water per day, unless your doctor advises otherwise. Avoid sugary drinks and excessive caffeine intake, as these can negatively impact your blood sugar control.
• Store SITASON DM 1000MG TABLET 10'S at room temperature, away from moisture and heat. Keep the medication in its original container and out of reach of children. Proper storage helps maintain the medication's effectiveness and prevents accidental ingestion.
• Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are essential for monitoring your overall health and managing your diabetes effectively. These appointments allow your doctor to assess your progress, make any necessary adjustments to your treatment plan, and address any concerns you may have.
• If you experience any unusual side effects while taking SITASON DM 1000MG TABLET 10'S, contact your doctor immediately. Common side effects may include nausea, diarrhea, and abdominal discomfort. While some side effects may be mild and temporary, it's important to report any persistent or severe symptoms to your healthcare provider.
• Carry a medical identification card or wear a medical alert bracelet indicating that you have diabetes and are taking SITASON DM 1000MG TABLET 10'S. This information can be crucial in case of an emergency, ensuring that you receive appropriate medical care. Make sure the card or bracelet includes emergency contact information.